ISBN: 9786630160284 - formulation and in-vitro assessment of chlorzoxazone buccal tablets (4 Ergebnisse)

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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Chlorzoxazone is a centrally acting skeletal muscle relaxant widely used for the treatment of painful musculoskeletal conditions such as muscle spasms, sprains, and strains. Although it is effective, its conventional oral dosage forms are associated with certain limitations, including rapid absorption and short biological half-life, which necessitate frequent dosing. Moreover, extensive first-pass hepatic metabolism reduces its overall bioavailability. To overcome these challenges, buccal drug delivery systems have gained significant attention. The buccal route, involving drug administration through the oral mucosa, offers several advantages such as avoidance of first-pass metabolism, improved bioavailability, ease of administration, and the possibility of controlled or sustained drug release. Buccal tablets are particularly useful as they can adhere to the mucosal surface and release the drug gradually over an extended period. The present formulation work focuses on the development of Chlorzoxazone buccal tablets designed for sustained drug release, aiming to improve therapeutic efficacy, reduce dosing frequency, and enhance patient compliance.…

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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Chlorzoxazone is a centrally acting skeletal muscle relaxant widely used for the treatment of painful musculoskeletal conditions such as muscle spasms, sprains, and strains. Although it is effective, its conventional oral dosage forms are associated with certain limitations, including rapid absorption and short biological half-life, which necessitate frequent dosing. Moreover, extensive first-pass hepatic metabolism reduces its overall bioavailability. To overcome these challenges, buccal drug delivery systems have gained significant attention. The buccal route, involving drug administration through the oral mucosa, offers several advantages such as avoidance of first-pass metabolism, improved bioavailability, ease of administration, and the possibility of controlled or sustained drug release. Buccal tablets are particularly useful as they can adhere to the mucosal surface and release the drug gradually over an extended period. The present formulation work focuses on the development of Chlorzoxazone buccal tablets designed for sustained drug release, aiming to improve therapeutic efficacy, reduce dosing frequency, and enhance patient compliance. 52 pp. Englisch.…

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Taschenbuch. Zustand: Neu. Formulation and In-Vitro Assessment of Chlorzoxazone Buccal Tablets | Vinod Kumar Dhote (u. a.) | Taschenbuch | Englisch | 2026 | LAP LAMBERT Academic Publishing | EAN 9786630160284 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu Print on Demand.…