9789401780759 - site-directed insertion of transgenes (topics in current genetics, band 23) (8 Ergebnisse)
Sprache: Englisch
Verlag: Springer, 2014
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Sprache: Englisch
Verlag: Springer, 2014
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Sprache: Englisch
Verlag: Springer, 2014
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strateg…ies. Genomic modifications such as knock-in, knock-out, knock-down, sequence replacement or modification can today be routinely performed. However, in front of this large palette of methodologies scientists may experience difficulties to gather useful information's scattered within the literature. This book aims to present the state of this field from basic mechanisms of site-directed modifications to their applications in a wide range of organisms such as bacteria, yeast, plants, insects, mammals. It will discuss the problems encountered when using the random integration strategy and present the recent advances made in targeted genome modification. Technologies based on Zinc Finger nucleases, Meganucleases, TALEN, CRE and FLP recombinase, C31 integrase, transposases and resolvases are fully detailed with their strengths and weaknesses. All these information's will help students and experienced researchers to understand and choose the best technology for their own purposes.
Sprache: Englisch
Verlag: Springer, 2014
- Softcover
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Sprache: Englisch
Verlag: Springer, 2014
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Sprache: Englisch
Verlag: Springer Netherlands Aug 2014, 2014
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene… therapy strategies. Genomic modifications such as knock-in, knock-out, knock-down, sequence replacement or modification can today be routinely performed. However, in front of this large palette of methodologies scientists may experience difficulties to gather useful information's scattered within the literature. This book aims to present the state of this field from basic mechanisms of site-directed modifications to their applications in a wide range of organisms such as bacteria, yeast, plants, insects, mammals. It will discuss the problems encountered when using the random integration strategy and present the recent advances made in targeted genome modification. Technologies based on Zinc Finger nucleases, Meganucleases, TALEN, CRE and FLP recombinase, C31 integrase, transposases and resolvases are fully detailed with their strengths and weaknesses. All these information's will help students and experienced researchers to understand and choose the best technology for their own purposes. 408 pp. Englisch.
Sprache: Englisch
Verlag: Springer Netherlands, 2014
- Softcover
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. No other book published in this field of research Presentation of all the innovative methodologies in genome engineering From basic science to practical applications Concerns a broad range of organisms (from bacteria to… mammals) .
Sprache: Englisch
Verlag: Springer Netherlands, Springer Netherlands Aug 2014, 2014
- Softcover
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene the…rapy strategies. Genomic modifications such as knock-in, knock-out, knock-down, sequence replacement or modification can today be routinely performed. However, in front of this large palette of methodologies scientists may experience difficulties to gather useful information¿s scattered within the literature. This book aims to present the state of this field from basic mechanisms of site-directed modifications to their applications in a wide range of organisms such as bacteria, yeast, plants, insects, mammals. It will discuss the problems encountered when using the random integration strategy and present the recent advances made in targeted genome modification. Technologies based on Zinc Finger nucleases, Meganucleases, TALEN, CRE and FLP recombinase, ¿C31 integrase, transposases and resolvases are fully detailed with their strengths and weaknesses. All these information¿s will help students and experienced researchers to understand and choose the best technology for their own purposes.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 408 pp. Englisch.
