cationic polymers based non viral von pathak atul (8 Ergebnisse)

Zustand: New. pp. 156.

Taschenbuch. Zustand: Neu. Neuware -Nucleic acids-based next generation biopharmaceuticals (i.e., oligonucleotides, siRNA) are potential therapeutic agents have ability to cope with various incurable diseases. However, several biological barriers present a challenge for efficient gene delivery. Inception of nanotechnology now offer numerous non-viral vectors that have been fabricated and found capable of transmitting the biopharmaceuticals into the cell and even into specific subcellular compartments like mitochondria. This book illustrates novel chemically modified polyallylamine and polyethylenimine based nano- vectors for enhanced gene delivery. Modification of these polymers using imidazolyl and polysaccharides such as hyaluronic acid, chondroitin sulfate and heparin not only improve cytotoxicity index but also provides site-specificity for cell-type specific gene delivery. Incorporation of targeting moiety minimizes the chance of potential adverse effects and also reduces the amount the amount of dose required to achieve desired therapeutic effects. Recent developments in formulation of efficient drug carriers showed potential to develop gene therapy again diseases like cancer.Books on Demand GmbH, Überseering 33, 22297 Hamburg 156 pp. Englisch.

Paperback. Zustand: Like New. Like New. book.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nucleic acids-based next generation biopharmaceuticals (i.e., oligonucleotides, siRNA) are potential therapeutic agents have ability to cope with various incurable diseases. However, several biological barriers present a challenge for efficient gene delivery. Inception of nanotechnology now offer numerous non-viral vectors that have been fabricated and found capable of transmitting the biopharmaceuticals into the cell and even into specific subcellular compartments like mitochondria. This book illustrates novel chemically modified polyallylamine and polyethylenimine based nano- vectors for enhanced gene delivery. Modification of these polymers using imidazolyl and polysaccharides such as hyaluronic acid, chondroitin sulfate and heparin not only improve cytotoxicity index but also provides site-specificity for cell-type specific gene delivery. Incorporation of targeting moiety minimizes the chance of potential adverse effects and also reduces the amount the amount of dose required to achieve desired therapeutic effects. Recent developments in formulation of efficient drug carriers showed potential to develop gene therapy again diseases like cancer. 156 pp. Englisch.

Zustand: New. Print on Demand pp. 156 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Pathak AtulDr. Atul Pathak is a Research Fellow at Immune Disease Institute, Program and Cellular and Molecular Medicine at Children Hospital, Harvard Medical School, Boston, USA. He earned his Ph.D. in Pharmaceutical Science. D.

Zustand: New. PRINT ON DEMAND pp. 156.

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Nucleic acids-based next generation biopharmaceuticals (i.e., oligonucleotides, siRNA) are potential therapeutic agents have ability to cope with various incurable diseases. However, several biological barriers present a challenge for efficient gene delivery. Inception of nanotechnology now offer numerous non-viral vectors that have been fabricated and found capable of transmitting the biopharmaceuticals into the cell and even into specific subcellular compartments like mitochondria. This book illustrates novel chemically modified polyallylamine and polyethylenimine based nano- vectors for enhanced gene delivery. Modification of these polymers using imidazolyl and polysaccharides such as hyaluronic acid, chondroitin sulfate and heparin not only improve cytotoxicity index but also provides site-specificity for cell-type specific gene delivery. Incorporation of targeting moiety minimizes the chance of potential adverse effects and also reduces the amount the amount of dose required to achieve desired therapeutic effects. Recent developments in formulation of efficient drug carriers showed potential to develop gene therapy again diseases like cancer.