Drug dna interaction protocols (32 Ergebnisse)

Titel: 
Mit der Detailsuche verfeinern

Optimieren Sie Ihre Suche

  • Bücher (32)

bis

Benutzerdefinierte Preisspanne (EUR)

bis

  • Sprache: Englisch

    Verlag: Humana Press, Totowa, NJ., 1997

    089603447X / 9780896034471

    • Hardcover

    Anbieter: Tiber Books, Cockeysville, MD, USATiber Books

    Verkäufer/-in mit 4 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Gut

    EUR 28,44

    EUR 4,89 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    Hardcover. Zustand: Very Good. 8vo, hardcover. No dj. Vg condition. Non-circulating ex-lib copy w/ light markings to opening pgs; contents bright, crisp & clean, virtually unopened. x, 278 p., illus.

  • Sprache: Englisch

    Verlag: Humana Press, 1997

    089603447X / 9780896034471

    • Hardcover

    Anbieter: Anybook.com, Lincoln, Vereinigtes KönigreichAnybook.com

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Befriedigend

    EUR 45,40

    EUR 15,53 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: 1 verfügbar

    Zustand: Good. Volume 90. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,750grams, ISBN:9780896034471. …

  • Sprache: Englisch

    Verlag: Humana Press, Totowa, N.J., 2010

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Research Ink, Takoma Park, MD, USAResearch Ink

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Gut

    EUR 59,64

    EUR 3,56 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    Hardback. Zustand: Very Good. xi + 318 pp. Methods in Molecular Biology. Rubber-stamped on front free endpaper. book.

  • Sprache: Englisch

    Verlag: Humana, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Basi6 International, Irving, TX, USABasi6 International

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 67,57

     Versand gratis 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    Zustand: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

  • Sprache: Englisch

    Verlag: Humana Press, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Books Puddle, Woodside, NY, USABooks Puddle

    Verkäufer/-in mit 4 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 86,57

    EUR 3,55 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    Zustand: New. pp. 332.

  • Sprache: Englisch

    Verlag: Humana Press, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Majestic Books, Hounslow, Vereinigtes KönigreichMajestic Books

    Verkäufer/-in mit 4 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 85,16

    EUR 7,74 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: 1 verfügbar

    Zustand: New. pp. 332 103 Illus. (1 Col.).

  • Sprache: Deutsch

    Verlag: HUMANA PRESS, 1997

    089603447X / 9780896034471

    • Hardcover

    Anbieter: Martin Preuß / Akademische Buchhandlung Woetzel, Kerzenheim, DeutschlandMartin Preuß / Akademische Buchhandlung Woetzel

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Verbandsmitglied: BOEV

    Zustand: Gebraucht - Wie neu

    EUR 34,90

    EUR 15,90 Versand 
    Versand von Deutschland nach USA

    Anzahl: 5 verfügbar

    32. Zustand: Wie neu. 1997. 274 pp., numerous figs., hardcover Cookbook-style instructions describe techniques developed to explore the interaction of drugs and ligands with DNA. The methods involve sequence recognition properties, as well as the physical approaches for measuring both the strength of interaction and Sprache: Deutsch.…

  • Sprache: Englisch

    Verlag: Humana, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 118,68

    EUR 2,35 Versand 
    Versand innerhalb von USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: New.

  • Sprache: Englisch

    Verlag: Humana, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: California Books, Miami, FL, USACalifornia Books

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 121,11

     Versand gratis 
    Versand innerhalb von USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: New.

  • Sprache: Englisch

    Verlag: Humana, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Wie neu

    EUR 127,17

    EUR 2,35 Versand 
    Versand innerhalb von USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: As New. Unread book in perfect condition.

  • Sprache: Englisch

    Verlag: Humana, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: GreatBookPricesUK, Woodford Green, Vereinigtes KönigreichGreatBookPricesUK

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 121,54

    EUR 17,87 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: New.

  • Sprache: Englisch

    Verlag: Humana, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes KönigreichRia Christie Collections

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 130,92

    EUR 13,45 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: New. In English.

  • Sprache: Englisch

    Verlag: Humana Press Inc., 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Kennys Bookshop and Art Galleries Ltd., Galway, GY, IrlandKennys Bookshop and Art Galleries Ltd.

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 132,41

    EUR 9,50 Versand 
    Versand von Irland nach USA

    Anzahl: 15 verfügbar

    Zustand: New. The last few years have witnessed the creation of new generations of sequence reading compounds, which have incredible potential for targeting specific DNA sequences. In this authoritative and current book, expert researchers explore these compounds. Editor(s): Fox, K. R. Series: Methods in Molecular Biology. Num Pages: 311 pages, 102 black & white illustrations, 1 colour illustrations, 11 black & white tables, biograp. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 25. Weight in Grams: 894. . 2009. 2nd ed. 2010. Hardback. . . . . …

  • Sprache: Englisch

    Verlag: Humana, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: GreatBookPricesUK, Woodford Green, Vereinigtes KönigreichGreatBookPricesUK

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Wie neu

    EUR 132,44

    EUR 17,87 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: As New. Unread book in perfect condition.

  • Sprache: Englisch

    Verlag: Humana Press, 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Buchpark, Trebbin, DeutschlandBuchpark

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Sehr gut

    EUR 55,00

    EUR 105,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 332 | Sprache: Englisch | Produktart: Bücher | DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases. Each of these advances has required the availability and development of an arsenal of techniques for probing the interactions in both qualitative and quantitative terms. This v- ume of Methods in Molecular Biology brings together several techniques that are currently useful for examining these interactions. Some of these are updates on ones that were included in the earlier volume (Methods in Molecular Biology 90), published 12 years ago, while others are new.…

  • Sprache: Englisch

    Verlag: Springer Verlag, 2010

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Revaluation Books, Exeter, Vereinigtes KönigreichRevaluation Books

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 161,38

    EUR 14,89 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: 2 verfügbar

    Hardcover. Zustand: Brand New. 2nd edition. 318 pages. 10.25x7.25x1.00 inches. In Stock.

  • Sprache: Englisch

    Verlag: Humana Press Inc., 2009

    1603274170 / 9781603274173

    • Hardcover

    Anbieter: Kennys Bookstore, Olney, MD, USAKennys Bookstore

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 170,33

    EUR 9,35 Versand 
    Versand innerhalb von USA

    Anzahl: 15 verfügbar

    Zustand: New. The last few years have witnessed the creation of new generations of sequence reading compounds, which have incredible potential for targeting specific DNA sequences. In this authoritative and current book, expert researchers explore these compounds. Editor(s): Fox, K. R. Series: Methods in Molecular Biology. Num Pages: 311 pages, 102 black & white illustrations, 1 colour illustrations, 11 black & white tables, biograp. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 25. Weight in Grams: 894. . 2009. 2nd ed. 2010. Hardback. . . . . Books ship from the US and Ireland. …

  • Sprache: Englisch

    Verlag: Humana, 2012

    1617796743 / 9781617796746

    • Softcover

    Anbieter: preigu, Osnabrück, Deutschlandpreigu

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 140,10

    EUR 70,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 5 verfügbar

    Taschenbuch. Zustand: Neu. Drug-DNA Interaction Protocols | Keith R. Fox | Taschenbuch | ix | Englisch | 2012 | Humana | EAN 9781617796746 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

  • Sprache: Englisch

    Verlag: Humana Press, 2012

    1617796743 / 9781617796746

    • Softcover

    Anbieter: Books Puddle, Woodside, NY, USABooks Puddle

    Verkäufer/-in mit 4 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 234,93

    EUR 3,55 Versand 
    Versand innerhalb von USA

    Anzahl: 4 verfügbar

    Zustand: New. pp. ix + 311 2nd Edition.

  • Sprache: Englisch

    Verlag: Humana Pr Inc, 2012

    1617796743 / 9781617796746

    • Softcover

    Anbieter: Revaluation Books, Exeter, Vereinigtes KönigreichRevaluation Books

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 232,06

    EUR 14,89 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: 1 verfügbar

    Paperback. Zustand: Brand New. 2nd edition. 320 pages. 10.00x7.01x0.78 inches. In Stock.

  • Sprache: Englisch

    Verlag: Humana Press Dez 2009, 2009

    1603274170 / 9781603274173

    • Hardcover
    • Print-on-Demand

    Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, DeutschlandBuchWeltWeit Ludwig Meier e.K.

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 106,99

    EUR 23,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 2 verfügbar

    Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases. Each of these advances has required the availability and development of an arsenal of techniques for probing the interactions in both qualitative and quantitative terms. This v- ume of Methods in Molecular Biology brings together several techniques that are currently useful for examining these interactions. Some of these are updates on ones that were included in the earlier volume (Methods in Molecular Biology 90), published 12 years ago, while others are new. 332 pp. Englisch.…

  • Sprache: Englisch

    Verlag: Humana, 2012

    1617796743 / 9781617796746

    • Softcover
    • Print-on-Demand

    Anbieter: Brook Bookstore On Demand, Napoli, NA, ItalienBrook Bookstore On Demand

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 126,26

    EUR 6,80 Versand 
    Versand von Italien nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: new. Questo è un articolo print on demand.

  • Sprache: Englisch

    Verlag: Humana Press, 2009

    1603274170 / 9781603274173

    • Hardcover
    • Print-on-Demand

    Anbieter: moluna, Greven, Deutschlandmoluna

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 89,99

    EUR 48,99 Versand 
    Versand von Deutschland nach USA

    Anzahl: Mehr als 20 verfügbar

    Gebunden. Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Fully updated from the first edition to include up-to-date methods for studying drug-DNA interactionsWritten by experts with hands-on experience of the techniquesCombines a wide range of approaches for analyzing drug-DNA interactions, from .…

  • Sprache: Englisch

    Verlag: Humana Press, 2009

    1603274170 / 9781603274173

    • Hardcover
    • Print-on-Demand

    Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 121,81

    EUR 35,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    Buch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases. Each of these advances has required the availability and development of an arsenal of techniques for probing the interactions in both qualitative and quantitative terms. This v- ume of Methods in Molecular Biology brings together several techniques that are currently useful for examining these interactions. Some of these are updates on ones that were included in the earlier volume (Methods in Molecular Biology 90), published 12 years ago, while others are new.…

  • Sprache: Englisch

    Verlag: Humana Dez 2009, 2009

    1603274170 / 9781603274173

    • Hardcover
    • Print-on-Demand

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschlandbuchversandmimpf2000

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 106,99

    EUR 60,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases. Each of these advances has required the availability and development of an arsenal of techniques for probing the interactions in both qualitative and quantitative terms. This v- ume of Methods in Molecular Biology brings together several techniques that are currently useful for examining these interactions. Some of these are updates on ones that were included in the earlier volume (Methods in Molecular Biology 90), published 12 years ago, while others are new.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 332 pp. Englisch.…

  • Sprache: Englisch

    Verlag: Humana Press, 2012

    1617796743 / 9781617796746

    • Softcover
    • Print-on-Demand

    Anbieter: moluna, Greven, Deutschlandmoluna

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 132,75

    EUR 48,99 Versand 
    Versand von Deutschland nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Fully updated from the first edition to include up-to-date methods for studying drug-DNA interactionsWritten by experts with hands-on experience of the techniquesCombines a wide range of approaches for analyzing drug-DNA interactions, from .…

  • Sprache: Englisch

    Verlag: Humana Press, Humana Press Mär 2012, 2012

    1617796743 / 9781617796746

    • Softcover
    • Print-on-Demand

    Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, DeutschlandBuchWeltWeit Ludwig Meier e.K.

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 160,49

    EUR 23,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 2 verfügbar

    Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases. Each of these advances has required the availability and development of an arsenal of techniques for probing the interactions in both qualitative and quantitative terms. This v- ume of Methods in Molecular Biology brings together several techniques that are currently useful for examining these interactions. Some of these are updates on ones that were included in the earlier volume (Methods in Molecular Biology 90), published 12 years ago, while others are new. 332 pp. Englisch.…

  • Sprache: Englisch

    Verlag: Humana Press, 2009

    1603274170 / 9781603274173

    • Hardcover
    • Print-on-Demand

    Anbieter: Biblios, frankfurt am main, HESSE, DeutschlandBiblios

    Verkäufer/-in mit 4 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 182,19

    EUR 9,95 Versand 
    Versand von Deutschland nach USA

    Anzahl: 4 verfügbar

    Zustand: New. PRINT ON DEMAND pp. 332.

  • Sprache: Englisch

    Verlag: Humana, 2012

    1617796743 / 9781617796746

    • Softcover
    • Print-on-Demand

    Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 178,75

    EUR 35,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases. Each of these advances has required the availability and development of an arsenal of techniques for probing the interactions in both qualitative and quantitative terms. This v- ume of Methods in Molecular Biology brings together several techniques that are currently useful for examining these interactions. Some of these are updates on ones that were included in the earlier volume (Methods in Molecular Biology 90), published 12 years ago, while others are new.…

  • Sprache: Englisch

    Verlag: Humana Mär 2012, 2012

    1617796743 / 9781617796746

    • Softcover
    • Print-on-Demand

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschlandbuchversandmimpf2000

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 160,49

    EUR 60,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases. Each of these advances has required the availability and development of an arsenal of techniques for probing the interactions in both qualitative and quantitative terms. This v- ume of Methods in Molecular Biology brings together several techniques that are currently useful for examining these interactions. Some of these are updates on ones that were included in the earlier volume (Methods in Molecular Biology 90), published 12 years ago, while others are new.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 332 pp. Englisch.…