Epigenetics protocols (181 Ergebnisse)

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Zustand: Good. Volume 631. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,750grams, ISBN:9781607616450. …

Hardback. Zustand: As new. 492 pp. Methods in Molecular Biology, volume 863. book.

Hardcover. Zustand: gut. 2012 | 2012 ed. The epigenetic regulation plays an important role in normal development and maintenance of tissue specific genes expression in humans and the disturbance of these patterns lead to changes involved in tumor formation. More recently, epigenetic changes have been observed in early stages of tumor development and together with the genetic alterations have been defined as abnormalities, necessary for cancer initiation and progression. In, Cancer Epigenetics: Methods and Protocols, expert researchers reviewed these epigenetics changes in different tumor types and described several technologies that are currently available to detect epigenetic changes. These technologies have lead to a better understanding of the processes in normal and cancerous cells. Written in the highly successful Methods in Molecular Biology (TM) series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Cancer Epigenetics: Methods and Protocols aids scientists in continuing to study epigenetic alterations used in clinical practice as biomarkers of early cancerous lesions or markers of progression and prognosis. Content: Part I: Early Epigenetic Events in Cancer 1. Epigenetic Markers of Early Tumor Development Ramona G. Dumitrescu 2. Epigenetics of Solid Cancer Stem Cells Alok Mishra and Mukesh Verma Part II: Cancer Specific Type Epigenetic Changes 3. DNA Methylation and Histone Modifications in Breast Cancer Ramona G. Dumitrescu 4. DNA Methylation Changes in Prostate Cancer Wolfgang Goering, Michael Kloth, Wolfgang A. Schulz 5. DNA Methylation in Promoter Region as Biomarkers in Prostate Cancer Mihi Yang and Jong Y. Park 6. Epigenetics of Bladder Cancer Wun-Jae Kim and Yong-June Kim 7. Epigenetics in Myeloid Malignancies Stefan Deneberg 8. The Epigenetics of Brain Tumors Adrian M. Dubuc, Stephen Mack, Alexander Unterberger, Paul A. Northcott and Michael D. Taylor 9. DNA Methylation Changes in Cervical Cancers Qiang Lu, Dehua Ma, Shuping Zhao 10. Epigenetics of Colon Cancer Sharad Khare and Mukesh Verma 11. Promoter Methylation in Head and Neck Tumorigenesis Josena K. Stephen, Kang Mei Chen, Shaleta Havard, Glynis Harris, Maria J. Worsham 12. Epigenome and DNA Methylation in Oral Squamous Cell Carcinoma Mario Perez-Sayans Garcia and Abel Garcia-Garcia 13. Clinical Implications of Epigenetic Alterations in Human Thoracic Malignancies: Epigenetic Alterations in Lung Cancer Keiko Shinjo and Yutaka Kondo 14. The Role of microRNAs in the Management of Liver Cancer Krishna K Banaudha and Mukesh Verma 15. Epigenetics in Ovarian Cancer L.M.S. Seeber, P.J. van Diest Part III: Methods and Technologies used for Epigenetic Changes Detection 16. DNA Methylation in Pancreatic Cancer: Protocols for the Isolation of DNA and Bisulfite Modification Katja Biewusch, Marie Heyne, Robert Grutzmann, Christian Pilarsky 17.Detection and Analysis of DNA Methylation by Pyrosequencing Hilary A. A. Colyer, Richard N. Armstrong, Dr. Daniel J. Sharpe and Ken I. Mills 18. Screening for miRNA Experssion Changes using Quantitative PCR (Q-PCR) Richard N. Armstrong, Hilary A. A. Colyer, Ken. I. Mills 19. Genome-wide Methylation Analysis Alexander Unterberger, Adrian M. Dubuc and Michael D. Taylor 20. Microarray for Epigenetic Changes: Gene Expression Arrays Hilary A. A. Colyer, Richard N. Armstrong and Ken I. Mills 21. Detecting DNA Methylation using the Methylated CpG Island Amplification and Microarray Technique Hiliary A. A. Colyer, Margaret Dellett and Ken I. Mills Part IV. Factors that Influence the Epigenetic Changes in Cancer 22. Nutrigenomics-Implications for Breast and Colon Cancer Prevention Gabriela Riscuta and Ramona G. Dumitrescu 23. Dietary and Lifestyle Factors of DNA Methylation Unhee Lim and Min-Ae Song 24. Diet, Epigenetics and Cancer Joseph L. Su 25. Role of Epigenetics in Cancer Health Disparities Sulma I. Mohammed, Sanya Springfield, and Rina Das 26. Multifactorial Etiology of Gastric Cancer Rosa A. Sierra, Jovanny Zabaleta Part V. Epigenetic Epidemiology 27. Epigenetic Epidemiology for Cancer Risk: Harnessing Germline Epigenetic Variation Kevin Brennan and James M. Flanagan 28. Epigenetic Biomarkers in Cancer Epidemiology Mukesh Verma Reihe/Serie Methods in Molecular Biology ; 863 Zusatzinfo 19 Tables, black and white; 32 Illustrations, color; 10 Illustrations, black and white; XIII, 492 p. 42 illus., 32 illus. in color. Verlagsort Totowa, NJ Sprache englisch Maße 178 x 254 mm Medizin Pharmazie Medizinische Fachgebiete Onkologie Studium 2. Studienabschnitt Klinik Humangenetik ISBN-10 1-61779-611-5 1617796115 ISBN-13 978-1-61779-611-1 9781617796111 In englischer Sprache. 492 pages. 178 x 254 mm.…

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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 284 | Sprache: Englisch | Produktart: Bücher | The discovery of DNA as the genetic material brought great hope to scientists all over the world. It was believed that many of the lingering questions in genetics and the mechanisms of heredity would fnally be answered. However, as often is the case in science, more qu- tions arose out of this discovery. What defnes a gene? What are the mechanisms of gene regulation? Further discovery and technological innovations brought about sequencing techniques that allowed the study of complete genomes from many organisms, including Arabidopsis and humans. Despite all the excitement surrounding these technologies, many features of the genome remained unclear. Peculiar characteristics in genome composition such as signifcant redundancy consisting of many repetitive elements and noncoding sequences, active transcriptional units with no protein product, and unusual sequences in promoter regions added to the mysteries of genetic make-up and gene regulation. Indeed, the more we discovered about the genome, the more diffcult it became to understand the complexity of cellular function and regulation. Out of the study of the intricacies of the genome and gene regulation, arose a new science that was independent of actual DNA changes, but critical in maintaining gene regulation and genetic stability. Epigenetics, literally translated as ¿above genetics,¿ is the science that describes the mechanisms of heritable changes in gene regulation that does not involve modifcations of DNA sequence. These changes may last through somatic cell division and, in some cases, throughout multiple generations.…

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