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In den WarenkorbZustand: Good. Volume 68. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,600grams, ISBN:9780127098685.
Verlag: Wageningen. Ponsen & Looijen.
ISBN 10: 906464294X ISBN 13: 9789064642944
Anbieter: Antiquariaat Ovidius, Bredevoort, Niederlande
Zustand: Gebraucht / Used. 2008. Pap. 128pp. 8°. Diss./Thesis. Blibliogr.
Taschenbuch. Zustand: Neu. Transcription Induction Integrated by Nuclear Receptor Coregulators | Chromatin, SF-1, and CtBP Structural and Post- Translational Modifications Induced by ACTH/cAMP Accelerate CYP17 Transcription Rate | Eric Dammer | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783836475327 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
Sprache: Englisch
Verlag: World Scientific Publishing Company, 2008
ISBN 10: 9812705368 ISBN 13: 9789812705365
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Sprache: Englisch
Verlag: World Scientific Publishing Company, 2008
ISBN 10: 9812705368 ISBN 13: 9789812705365
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In den WarenkorbPaperback. Zustand: Brand New. 300 pages. 10.00x7.00x0.68 inches. In Stock.
Sprache: Englisch
Verlag: Elsevier, 2004
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In den WarenkorbKartoniert / Broschiert. Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Dammer EricEric Dammer was raised in Bergen County, New Jersey. He studied nat UC Santa Cruz and later finished undergraduate studies at nFlorida Gulf Coast University in Ft. Myers, Florida in 2003. He nwas an HHMI intern at Georgi.
Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Studies carried out during the past decade have shown that transcription of inducible eukaryotic genes involves sequential chromatin modifications by promoter-specific transcription factors and a class of proteins called transcription coregulators. First, this work identifed important chromatin modifications and modifying complexes at the CYP17 transcription start site and nearby steroidogenic factor-1 (SF-1) binding site. Post translational modifications (PTMs) to SF-1 also occur as this transcription factor interacts with the promoter. In addition, ACTH/cAMP signaling in adrenal cortex alters SF-1-containing chromatin-modifying complexes during the early phase of transcriptional induction of CYP17. Chromatin IP (ChIP) and mammalian two hybrid experiments identified complexes which are cAMP-inducible, but sensitive to the SF-1 antagonist sphingosine. SF-1 PTMs at the ligand binding pocket opening were found to be required for CYP17 transcription. Last, certain corepressors are protein kinase A (PKA) targets and are functionally sensitive to PKA-dependent NADH accumulation. Thus, signaling, metabolism, and transcription are integrated.