Stroke genetics (59 Ergebnisse)

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1st edition. 8vo. xii + 346pp. B/w. illustrations, diagrams. Ownership inkstamp to half title and title page. Original pictorial mauve boards lettered in white. ISBN 0198515863 US$12.

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Zustand: Hervorragend. Zustand: Hervorragend | Seiten: 554 | Sprache: Englisch | Produktart: Bücher | I was thinking about writing a medical story book with a lot of visual arts on the most challenging human diseases, the heart- or brain-attack and the presumed vascular culprit: the platelet thrombus from its initiation, rapid maturation, migration, lodging in the critical, narrowing arteries of heart or brain, choking these hard-working organs to death by blocking the blood supply of vital oxygen and other nutrients. When they are healthy, the proteins, the cells of blood and the composite structure of artery do a great job in maintaining the vascular sanity, called homeostasis. For a variety of reasons from our inherent genetics and our unhealthy lifestyles, the endothelial cells of the inner wall of artery become unhappy, inflamed and become sticky to the white cells of blood, called the monocytes. They open their tightly interlocked junctions and invite the monocytes and let them stay put. However, these monocytes have their own plan and imbibe more protein-cholesterol particles, called low-density lipoprotein-cholesterol (LDL-C) and turned into monsters called macrophages, the big eaters. They also release the protein-fiber cutting enzymes, called matrix metalloproteases (MMPs), where they cut the collagen fibers synthesized by the smooth muscle cells (SMCs) of media.…

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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 554 | Sprache: Englisch | Produktart: Bücher | I was thinking about writing a medical story book with a lot of visual arts on the most challenging human diseases, the heart- or brain-attack and the presumed vascular culprit: the platelet thrombus from its initiation, rapid maturation, migration, lodging in the critical, narrowing arteries of heart or brain, choking these hard-working organs to death by blocking the blood supply of vital oxygen and other nutrients. When they are healthy, the proteins, the cells of blood and the composite structure of artery do a great job in maintaining the vascular sanity, called homeostasis. For a variety of reasons from our inherent genetics and our unhealthy lifestyles, the endothelial cells of the inner wall of artery become unhappy, inflamed and become sticky to the white cells of blood, called the monocytes. They open their tightly interlocked junctions and invite the monocytes and let them stay put. However, these monocytes have their own plan and imbibe more protein-cholesterol particles, called low-density lipoprotein-cholesterol (LDL-C) and turned into monsters called macrophages, the big eaters. They also release the protein-fiber cutting enzymes, called matrix metalloproteases (MMPs), where they cut the collagen fibers synthesized by the smooth muscle cells (SMCs) of media.…

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Zustand: Wie Neu. Zustandsbeschreibung: leichte Lagerspuren/minor shelfwear. Edited by Pankaj Sharma & James F. Meschia. This revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined inthe field of inherited stroke. Third Edition. XII,624 Seiten mit 32 Farb- und 18 s/w-Abb., gebunden (Springer 2024). Statt EUR 151,47. Gewicht: 1113 g - Gebunden/Gebundene Ausgabe.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined inthe field of inherited stroke.Additional questions via app: Download theSpringer Nature Flashcards app forfree and use exclusive additional material totest your knowledge.…

Zustand: new. This revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined inthe field of inherited stroke.Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge. This revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…