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Taschenbuch. Zustand: Neu. Neuware -Der Erhaltung vorhandener Bausubstanz und ihre Anpassung an neue Bedürfnisse kommt heute eine steigende Bedeutung zu. Das gilt auch für Tragkonstruktionen. Während Tragwerke in Stahl von vornherein anpassungfähiger sind, mussten entsprechende Möglichkeiten bei Betontragwerken erst geschaffen und entwickelt werden. Das nachträgliche Anbringen äußerer Bewehrung ist ein solches Verfahren. Mit diesem Verfahren ist es möglich, Mängel an bestehenden Konstruktionen zu beheben oder ihre Tragsicherheit und Gebrauchstauglichkeit neuen Einwirkungen - wie erhöhter Nutzlast oder veränderter Art der Beanspruchung - anzupassen.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 180 pp. Deutsch.

Taschenbuch. Zustand: Neu. Neuware -Die Bauwerksvermessung bildet die Grundlage für jede gründliche Bestandserfassung eines Gebäudes, seiner konstruktiven Zusammenhänge, des Bauzustandes und zu planende Baumaßnahmen. Sie erfasst das Bauwerk in seiner komplexen Form in einer angemessenen Detaillierung und bei Bedarf auch verformungsgetreu. Sie ist ein wesentlicher Bestandteil der Bauaufnahme im Rahmen von Sanierung, Modernisierung bzw. Umnutzung eines Gebäudes, aber auch bei Bauuntersuchungen für wissenschaftliche Zwecke der Haus- und Bauforschung und bei denkmalpflegerischen Maßnahmen.Die Bauwerksvermessung vereint methodisch das Handaufmaß mit Geodäsie, Photogrammetrie und Laserscanning. Der Autor bietet einen umfassenden Überblick und Anwenderwissen zum Thema Bauwerksvermessung. Die grundlegenden Verfahren Handaufmaß, Geodäsie, Photogrammetrie und Laserscanning bilden neben dem Management von Messprodukten an Bauwerken den Schwerpunkt des Buches. Das Buch ist ebenso geeignet als Nachschlagewerk über die derzeit aktuellen Verfahren und Methoden.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 336 pp. Deutsch.

Taschenbuch. Zustand: Neu. Neuware -Die nach Inhalt, Methode und sozialer Relevanz durchgreifenden Umwälzungen in Mathematik, Astronomie, Physik, Chemie, Biologie und Geographie sowie in Naturphilosophie und wissenschaftlichen Organisationsformen während des 16./17. und des beginnenden 18. Jahrhunderts werden in der Historiographie der Wissenschaften mit dem Sammelbegriff Wissenschaftliche Revolution schlechthin bezeichnet. Der Autor beschreibt in seinem Buch markante Höhepunkte jenes Prozesses, auf denen ganz wesentlich unsere heutige Wissenschaft gegründet ist. Um die geistigen Wendungen und die Persönlichkeiten hervortreten zu lassen, wurde großer Wert auf authentische Äußerungen jener Wissenschaftler gelegt.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 236 pp. Deutsch.

Taschenbuch. Zustand: Neu. Neuware -Eigenschaften von Singularitäten . . . . . . . . . . . . . . . . . . 49 4. 1 Der Umgebungsrand . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 4. 2 Gute Repräsentanten von Abbildungskeimen . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60 4. 3 Monodromie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 4. 4 Die Monodromie einer quadratischen Singularität (lokaler Fall) . . . . . . . . . . 65 5 Die U ntersuchung von Milnorfasern . . . . . . . . . . . . . . . . . ¿. . . ¿. . ¿¿. ¿ ¿. . . . . . . 73 5. 1 Milnorfasem von ebenen Kurvensingularitäten . . . . . . ¿. . ¿. . . ¿. . ¿. . . . . . . . . 73 5. 2 Milnorfasem von Hyperfiä. chensingularitäten . . . . . . . . . . . . . . ¿. . ¿. . . . . . . . . . 81 6 Die Beec r hnung d er M o n oro d mie . . . . . . . . . . . . . . . . . . . ¿. . . . . . ¿. . ¿ . . . . . . . . . 87 6. 1 Die Morsifikation . . . . , . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ¿. . . . . . . 87 6. 2 Die Monodromie der ebenen Kurvensingularitäten in Cl. . . . . . . . . . 88 6. 3 Dynkin-Dia. gramm und Monodromiegruppe . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 6. 4 Die Monodromie beim Addieren von FUnktionskeimen . . . . . . . . . . . . .Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 152 pp. Deutsch.

Taschenbuch. Zustand: Neu. Neuware -The history of mechanics, and more particularly, the history of mechanics applied to constructions, constitutes a field of research that is relatively recent. This volume, together with the recent publication 'Towards a History of Construction', is intended as an homage to the two eminent scholars who made a determinant contribution to the history of mechanics: Edoardo Benvenuto and Clifford Truesdell.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 260 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Myocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 532 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This book contains the refereed papers which were presented at the interna tional conference on 'Multivariate Approximation and Splines' held in Mannheim, Germany, on September 7-10,1996. Fifty experts from Bulgaria, England, France, Israel, Netherlands, Norway, Poland, Switzerland, Ukraine, USA and Germany participated in the symposium. It was the aim of the conference to give an overview of recent developments in multivariate approximation with special emphasis on spline methods. The field is characterized by rapidly developing branches such as approximation, data fit ting, interpolation, splines, radial basis functions, neural networks, computer aided design methods, subdivision algorithms and wavelets. The research has applications in areas like industrial production, visualization, pattern recognition, image and signal processing, cognitive systems and modeling in geology, physics, biology and medicine. In the following, we briefly describe the contents of the papers. Exact inequalities of Kolmogorov type which estimate the derivatives of mul the paper of BABENKO, KOFANovand tivariate periodic functions are derived in PICHUGOV. These inequalities are applied to the approximation of classes of mul tivariate periodic functions and to the approximation by quasi-polynomials. BAINOV, DISHLIEV and HRISTOVA investigate initial value problems for non linear impulse differential-difference equations which have many applications in simulating real processes. By applying iterative techniques, sequences of lower and upper solutions are constructed which converge to a solution of the initial value problem.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 340 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -to Deep Earth Electrical Conductivity.- Electromagnetic induction in the earth due to stationary and moving sources.- The new approach to global deep sounding.- The effect of the oceans and sedimentary cover on global magnetovariational field distribution.- The magnetospheric disturbance ring current as a source for probing the deep earth electrical conductivity.- The conductosphere depth at equatorial latitudes as determined from geomagnetic daily variations.- A deep geophysical study in the Baikal region.- A new telluric KCl probe using Filloux¿s AgAgCl electrode.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 100 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Arguably, many industrial optimization problems are of the multiobjective type. The present work, after providing a survey of the state of the art in multiobjective optimization, gives new insight into this important mathematical field by consequently taking up the viewpoint of differential geometry. This approach, unprecedented in the literature, very naturally results in a generalized homotopy method for multiobjective optimization which is theoretically well-founded and numerically efficient. The power of the new method is demonstrated by solving two real-life problems of industrial optimization.The book presents recent results obtained by the author and is aimed at mathematicians, scientists, students and practitioners interested in optimization and numerical homotopy methods.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 148 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This volume contains a selection of invited papers, presented to the fourth In Statistical Analysis Based on the L1-Norm and Related ternational Conference on Methods, held in Neuchatel, Switzerland, from August 4-9, 2002. Organized jointly by the University of Illinois at Chicago (Gib Bassett), the Rutgers University (Regina Liu and Yehuda Vardi) and the University of Neuchatel (Yadolah Dodge), the conference brought together experts whose research deals with theory and ap plications involving the L1-Norm. The conference included invited and contributed talks as well as a tutorial on Quantile Regression. This volume includes 36 refereed invited papers under seven headings. Part one deals with Quantiles in all their forms and shapes. It includes papers on quantile functions in non-parametric multivariate analysis, and empirical applications of quantile regression. Much of the development in this direction follows from the fundamental paper by Koenker and Bassett in 1978. Financial and Time Series A nalysis follows the section on quantiles. Part three concerns Estimation, Testing and Characterization. Part four, Deep in the Data, deals with issues related to data depth. Part five addresses Classification questions. The problem of Density Estimation and Image Processing is discussed in Part six, and finally Part seven presents two environmental applications. The contributions represent clear evidence of important research involving theo retical issues and applications associated with the L1-Norm. It is my hope that the articles contained in this volume and its predecessors, published in 1987, 1992, and 1997, will stimulate interest among researchers.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 472 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Gerhard Gentzen (1909-1945) ist der Begründer der modernen mathematischen Beweistheorie. Die nachhaltige Bedeutung der von ihm entwickelten Methoden, Regeln und Strukturen zeigt sich heute in wichtigen Teilgebieten der Informatik, in der Verifikation von Programmen. Die Arbeiten Gentzens über das natürliche Schliessen, der Sequenzenkalkül und die Ordinal-Beweistheorie beeindrucken noch heute durch ihre Einsicht und Eleganz. Der Autor dokumentiert in dieser ersten umfassenden Biografie Leben und Werk Gerhard Gentzens, seinen tragischen Lebensweg, Festnahme 1945 in Prag, Gefangenschaft und Tod. Die Bedingungen wissenschaftlicher Forschung, in diesem Fall der mathematischen Logik, im nationalsozialistischen Deutschland, den ideologischen Kampf um eine 'Deutsche Logik' und deren Protagonisten ist ein weiterer Schwerpunkt des Buches. Zahlreiche, bislang unveröffentlichte Quellen, Fotos und Dokumente aus Korrespondenzen und Nachlass sowie der Abdruck dreier Vorträge von Gerhard Gentzen machen dieses Buch zu einer erstrangigen Informationsquelle über diesen bedeutenden Mathematiker und seine Zeit. Der Band wird ergänzt durch ein Essay von Jan von Plato über Gentzens Beweistheorie und deren Entwicklung bis zur Gegenwart.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 432 pp. Deutsch.

Taschenbuch. Zustand: Neu. Neuware -Bioelectrochemistry of Membranes is the last volume in the book series 'Bioelectrochemistry: Principles and Practice' that provides a comprehensive compilation of physicochemical aspects of different biochemical and physiological processes. This sixth volume introduces basic knowledge and important electrochemical and biophysical aspects of membrane potentials, lipid bilayers and cell membranes.The volumes of this book series serve as source books for advanced students and researchers at all levels of bioelectrochemistry.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 256 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Nevanlinna-Pick interpolation for time-varying input-output maps: The discrete case.- 0. Introduction.- 1. Preliminaries.- 2. J-Unitary operators on 2.- 3. Time-varying Nevanlinna-Pick interpolation.- 4. Solution of the time-varying tangential Nevanlinna-Pick interpolation problem.- 5. An illustrative example.- References.- Nevanlinna-Pick interpolation for time-varying input-output maps: The continuous time case.- 0. Introduction.- 1. Generalized point evaluation.- 2. Bounded input-output maps.- 3. Residue calculus and diagonal expansion.- 4. J-unitary and J-inner operators.- 5. Time-varying Nevanlinna-Pick interpolation.- 6. An example.- References.- Dichotomy of systems and invertibility of linear ordinary differential operators.- 1. Introduction.- 2. Preliminaries.- 3. Invertibility of differential operators on the real line.- 4. Relations between operators on the full line and half line.- 5. Fredholm properties of differential operators on a half line.- 6. Fredholm properties of differential operators on a full line.- 7. Exponentially dichotomous operators.- 8. References.- Inertia theorems for block weighted shifts and applications.- 1. Introduction.- 2. One sided block weighted shifts.- 3. Dichotomies for left systems and two sided systems.- 4. Two sided block weighted shifts.- 5. Asymptotic inertia.- 6. References.- Interpolation for upper triangular operators.- 1. Introduction.- 2. Preliminaries.- 3. Colligations & characteristic functions.- 4. Towards interpolation.- 5. Explicit formulas for .- 6. Admissibility and more on general interpolation.- 7. Nevanlinna-Pick Interpolation.- 8. Carath¿ory-Fej¿interpolation.- 9. Mixed interpolation problems.- 10. Examples.- 11. Block Toeplitz & some implications.- 12. Varying coordinate spaces.- 13. References.- Minimality and realization of discrete time-varying systems.- 1. Preliminaries.- 2. Observability and reachability.- 3. Minimality for time-varying systems.- 4. Proofs of the minimality theorems.- 5. Realizations of infinite lower triangular matrices.- 6. The class of systems with constant state space dimension.- 7. Minimality and realization for periodical systems.- References.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 312 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Antioxidants inhibit the formation and spread of free radicals which can be damaging in biological systems. Free radicals form in biological systems through metabolism, but it is also realized that exogenous environmental sources, such as radiation, food, and drugs, contribute significantly to the generation of free radicals in biological systems. Being reactive species, free radicals are short-lived and do not travel far from cellular targets. Their concentration in biological systems is very low and is difficult to detect directly by electron spin resonance spectroscopy (ESR). Indirect methods of reactions of radicals with specific biomolecules are also sufficiently sensitive to detect quantitatively their presence. Thus the response of antioxidant defenses which react with radical species, can serve as an indirect measure that free radicals have been formed. Redox-based antioxidants change their oxidation state and antioxidants become free radicals themselves. Often, however, the antioxidants give rise to more persistent free radicals, sometimes owing to delocalization of the lone electron around ring structures (in vitamin E, ubiquinones, and certain carotenes). Persistent free radicals react only rarely and the precursors often can be regenerated in biological systems. In recent years, it is becoming clearer from biochemical studies on how the major lipophilic antioxidants work. Particular attention has been given to vitamin E and quinones found in animal and plant membranes and in carotenoids, for the protection of membranes in lipoprotein systems. Flavonoids form another rich and varied source of natural antioxidants.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 656 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This volume of 'Agents and Actions Supplements' provided a challenge to the editors, the authors and the publisher. It was our aim to complete the book in advance of the lectures to be given at the 'International Symposium on Asthma and Allergic Diseases in Childhood', in Berne, Switzerland, on March 25th-27th, 1993. This symposium commemorates the 10th anniversary of the Swiss Association of Parents of Asthmatic and Allergic Children. The incidence of asthma and allergies generally is on the increase and demands everyone's attention, including that of physicians, researchers, allied health professionals and parents. There have been no recent breakthroughs in our understanding of asthma pathogenesis or treatment. However, forms of treatment, pathogenetic insights and public awareness are undergoing rapid changes as our knowledge of atopic diseases increases. For this reason we chose the title 'Update on Childhood Asthma'. The purpose of the papers is to summarize recent research results, to provide an update on the current approach to therapeutic interventions and to alert readers to the psychosomatic aspects of asthma. Whether the state of knowledge has already changed while you are holding this book in your hands is not so much dependent on a delay in publishing but on the speed of appearance of new research results. Fortunately, our ambitious target to edit the proceedings in advance of the conference has been successful. This was only possible because of the timely submission of papers, the speed of publication and the enthusiasm of the editors.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 236 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The international symposium held in October 1984 at the Uni versity of Mannheim was the first with the special aim to expose the connection of the Theory of Delay Eauations and Approximation Theory with the emphasis on constructive methods and applications. Although the separate character of both domains is reflected by their historical development, the latest research shows that the numerical treatment of Delay Equations leads to various appro ximation and optimization problems. An introductory survey of this circle of problems written by the editors is included at the beginning of the book. Delay Equations have their origin in domains of applications, such as physics, engineering, biology, medicine and economics. They appear in connection with the fundamental problem to analyse a retarded process from the real world, to develop a corresponding mathematical model and to determine the future behavior. Thirty mathematicians attended the conference coming from Germany, West- and Eastern Europe and the United States- more than twenty of them presented a research talk. The lectures about Delay Equations were mainly oriented on the following subjects: single-step, multi-step and spline methods; monotonicity methods for error estimations; asymptotic behavior 10 and periodicity of solutions. The topics of the talks on Approxi mation Theory covered different aspects of approximation by poly nomials, splines and rational functions and their numerical rea lization. Additionally included in the scientific program was a special session on Open Problems, where several suggestions were made for further research concerning both fields.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 352 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The fields of boundary integral equations and of inequality problems, or more gen erally, of nonsmooth mechanics, have seen, in a remarkably short time, a considerable development in mathematics and in theoretical and applied mechanics. The engineering sciences have also benefited from these developments in that open problems have been attacked succesfully and entirely new methodologies have been developed. The contact problems of elasticity is a class of problems which has offered many open questions to deal with, both to the research workers working on the theory of boundary integral equations and to those working on the theory of inequality problems. Indeed, the area of static and dynamic contact problems could be considered as the testing workbench of the new developments in both the inequality problems and in the boundary integral equations. This book is a first attempt to formulate and study the boundary integral equations arising in inequality contact problems. The present book is a result of more than two decades of research and teaching activity of the first author on boundary integral equations and, of the second author, on inequality problems, as well as the outgrowth of seminars and courses for a variety of audiences in the Technical University of Aachen, the Aristotle University of Thessa loniki, the Universities of Bochum, of Hamburg and Braunschweig, the Pontificia Univ. Catolica in Rio de Janeiro etc.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 328 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Epidemiological studies of Chronic Bronchitis/ Chronic Obstructive Airway Disease (CB/COAD) have demonstrated that hypersecretory glandular activity, as weIl as infections, are not the most important risk factors determining the serious decline in lung function in this disease. Instead, inflammatory indices are emerging as characteristic features of the pathology and pathophysiology of CB/COAD. It is possible that continuous inflammatory processes cause structural changes and thus provide the anatomical basis for airway obstruction which, once estab lished, is only partly reversible. We feIt it was timely to gather leading international researchers who could provide critical updates on CB/COAD, its pathology and clinical/ experimental assessments. The latter aspect included not only the fundamentals of airway function but also, and in greater detail, cellular and solute indices which can now be used to determine inflammation in CB/COAD. The meeting was made possible by a grant from Draco/Astra (Sweden and Finland). We particularly acknowledge the expert assistance of Mrs. Eva Engberg in all facets of the present work.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 296 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -On June 28-29, 1990 in Noordwijk, The Netherlands, the International Association of Inflammation societies (IAIS) organized their first symposium on Drugs in Inflammation. The symposium was an official satellite of the Ixth International Congress of Pharmacology (IUPHAR). This volume contains the proceedings from this satellite meeting. The IAIS was constituted in 1988 when representatives of the Inflammation Research Association (IRA), European Workshop on Inflammation (EWI) and British Inflammation Research Association (BIRAs) met at White Haven, Pennsylvania during the Fourth International Conference of the IRA and the group decided that improved communication between inflammation societies could be achieved by establishment of a society. The IAIS would encourage and foster collaboration between the many inflammation societies throughout the world and assist in the establishment of new societies whenever possible. The satellite was a major success thanks to the efforts of the planning committee: Wim van den Berg, the local organizer, Mike Bray, the programme chairman, Rodger McMillan, Greg Harper, Mike Parnham and Kay Brune. In addition, the chairman and presenters ensured the scientific content of the meeting was of a very high standard. Most importantly, the 100 participants from 15 countries made the sessions lively and interactive. The IAIS will hopefully organize additional symposiums in the future. Alan J. Lewis, Ph.D.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 264 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Expanding from the classic use of immunosuppressants in transplantation and rejection, this current overview highlights their new roles in clinical medicine. Immunosuppressants are at the forefront of new treatment modalities. Individual chapters focus on their use not only in prevention or treatment of transplant rejection, but also on their use in immune-complex and autoimmune diseases, including rheumatoid arthritis; on combination therapies to achieve synergy in immunosuppression; on new drugs, low molecular weight chemicals, the use of antibodies and gene therapy; on immunological tolerance to prevent or inhibit transplant rejection; and how data derived from transplant studies can be applied to other avenues of immunosuppression. Clinicians and researchers will appreciate the scope of the work and the presentation of new approaches in the rapidly developing field of immunosuppression.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 236 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Massively Parallel Systems (MPSs) with their scalable computation and storage space promises are becoming increasingly important for high-performance computing. The growing acceptance of MPSs in academia is clearly apparent. However, in industrial companies, their usage remains low. The programming of MPSs is still the big obstacle, and solving this software problem is sometimes referred to as one of the most challenging tasks of the 1990's. The 1994 working conference on 'Programming Environments for Massively Parallel Systems' was the latest event of the working group WG 10.3 of the International Federation for Information Processing (IFIP) in this field. It succeeded the 1992 conference in Edinburgh on 'Programming Environments for Parallel Computing'. The research and development work discussed at the conference addresses the entire spectrum of software problems including virtual machines which are less cumbersome to program; more convenient programming models; advanced programming languages, and especially more sophisticated programming tools; but also algorithms and applications.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 440 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Progress in today's high-technology industries is strongly associated with the development of new mathematical tools. A typical illustration of this partnership is the mathematical modelling and numerical simulation of electric circuits and semiconductor devices. At the second Oberwolfach conference devoted to this important and timely field, scientists from around the world, mainly applied mathematicians and electrical engineers from industry and universities, presented their new results. Their contributions, forming the body of this work, cover electric circuit simulation, device simulation and process simulation. Discussions on experiences with standard software packages and improvements of such packages are included. In the semiconductor area special lectures were given on new modelling approaches, numerical techniques and existence and uniqueness results. In this connection, mention is made, for example, of mixed finite element methods, an extension of the Baliga-Patankar technique for a three dimensional simulation, and the connection between semiconductor equations and the Boltzmann equations.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 336 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The book will provide an overview of the roles of vascular adhesion molecules in health and disease, with chapters on their cell biology, followed by chapters reviewing their importance in specific disease processes. Vascular adhesion molecules are vital for the physiological processes of leukocyte trafficking and also critically involved in the enhanced leukocyte emigration that is a key feature of all inflammatory and immune diseases. The book is designed to provide up-to-date, linked reviews of the subject suitable for postgraduate students entering the field or research workers from allied disciplines needing a modern overview.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 276 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -In 1898 Camillo Golgi reported his newly observed intracellular structure, the apparato reticolare interno, now universally known as the Golgi Apparatus. The method he used was an ingenious histological technique (La reazione nera) which brought him fame for the discovery of neuronal networks and culminated in the award of the Nobel Prize for Physiology and Medicine in 1906. This technique, however, was not easily reproducible and led to a long-lasting controversy about the reality of the Golgi apparatus. Its identification as a ubiquitous organelle by electron microscopy turned out to be the breakthrough and incited an enormous wave of interest in this organelle at the end of the sixties. In recent years immunochemical techniques and molecular cloning approaches opened up new avenues and led to an ongoing resurgence of interest. The role of the Golgi apparatus in modifying, broadening and refining the structural information conferred by transcription/translation is now generally accepted but still incompletely understood. During the coming years, this topic certainly will remain center stage in the field of cell biology. The centennial of the discovery of this fascinating organelle prompted us to edit a new comprehensive book on the Golgi apparatus whose complexity necessitated the contributions of leading specialists in this field. This book is aimed at a broad readership of glycobiologists as well as cell and molecular biologists and may also be interesting for advanced students of biology and life sciences.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 320 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The human immune system, despite having its own sophisticated defence mecha nisms, is inferior to bacteria and viruses with respect to adaptability. Furthermore, our immune system is increasingly exposed to detrimental effects, that is immuno suppressive environmental consequences, unhealthy living, and chronic illnesses. Excessive chemotherapy threatens our immune system even further. This situation demands compensatory prophylactic therapeutic regimes. One of these - specific immunostimulation - is more difficult to achieve than the immunosuppression cur rently used in transplantation surgery and the medical treatment of autoimmune dis eases. The earliest attempts to develop suitable medication for immunostimulation were based on traditional remedies which embodied the accumulated experience of several centuries. Medicinal plants are already being used prophylactically as stan dardized and efficacy-optimized preparations for the treatment of various recur rent infections, or in combination with chemotherapeutics in standard medical practice. In order to rationally apply immunostimulants of plant origin, however, it is necessary to search for the active principles of these substances and to produce them in a pure form. Because suitable screening methods have become available only recently, research in this field is in its very beginning. Further progress can be expected from systematic basic research on the mechanisms underlying immunomodulation. This also applies to verification of clinical efficacy, which is a prerequisite for the acceptance of medications with purported immunostimulatory properties.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 388 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Lung cancer is a disease with pandemic public health implications as it is now the leading cause of cancer mortality throughout the world. This book results from two recent International Association for the Study of Lung Cancer (IASLC) Workshops on lung cancer prevention. It strikes a balance between considering public health approaches to tobacco control and population-based screening, advances in clinical evaluation of chemoprevention approaches, and the biology of lung carcinogenesis. Indeed, while the science of smoking cessation is evolving as new pharmacological tools are moving into clinical evaluation, the current impact of molecular diagnostics is profound. The rapidly-evolving diagnostic technologies are revolutionizing basic scientific investigation of cancer, and this trend is expected to soon spill over into the clinical practice of medicine. The evolution of economical diagnostic platforms to allow for direct bronchial epithelial evaluation in high-risk populations promises to improve the diagnostic lead-time for this disease. The hope is that enough progress will occur to permit lung cancer detection in advance of clinical cancer so that the disease can be addressed early on, while it is still confined to the site of origin. Chemoprevention, which is designed to intervene in the early phase of carcinogenesis prior to any subjective clinical manifestation of a cancer, is also generating greater research interest. Moreover, the benefit of aerosolized administration of chemoprevention agents over conventional oral administration has strong appeal and may result in the reduction of the incidence of cancer when combined with new diagnostic technologies.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 348 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 700 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -This volume contains the Proceedings of the International Workshop Variational Methods For Discontinuous Structures, which was jointly organized by the Dipar timento di Matematica Francesco Brioschi of Milano Politecnico and the Interna tional School for Advanced Studies (SISSA) of Trieste. The Conference took place at Villa Erba Antica (Cernobbio) on the Lago di Como on July 4- 6, 2001. In past years the calculus of variations faced mainly the study of continuous structures, say particularly problems with smooth solutions. One of the deepest and more delicate problems was the regularity of weak solutions. More recently, new sophisticated tools have been introduced in order to study discontinuities: in many variational problems solutions develop singularities, and sometimes the most interesting part of a solution is the singularity itself. The conference intended to focus on recent developments in this direction. Some of the talks were devoted to differential or variational modelling of image segmentation, occlusion and textures synthesizing in image analysis, varia tional description of micro-magnetic materials, dimension reduction and structured deformations in elasticity and plasticity, phase transitions, irrigation and drainage, evolution of crystalline shapes; in most cases theoretical and numerical analysis of these models were provided. viii Preface Other talks were dedicated to specific problems of the calculus of variations: variational theory of weak or lower-dimensional structures, optimal transport prob lems with free Dirichlet regions, higher order variational problems, symmetrization in the BV framework.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 204 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -For centuries, TK has been used almost exclusively by its creators, that is, indigenous and local communities. Access to, use of and handing down of TK has been regulated by local laws, customs and tmditions. Some TK has been freely accessible by all members of an indigenous or local community and has been freely exchanged with other communities; other TK has only been known to particular individuals within these communities such as shamans, and has been handed down only to particular individuals of thc next generation. Over many generations, indigenous and local communities have accumulated a great deal of TK which has generally been adapted, developed and improved by the generations that followed. For a long time, Western anthropologists and other scientists have generally been able to freely access TK and have documented it in their works. Still, this TK was only seldom used outside the indigenous and local communities that created it. More recently, however, Western scientists have become aware that TK is neither outdated nor valueless knowledge, but, instead, 1 can be useful to solve some of the problems facing today's world. Modem science, for example, has shown an increased interest in some fornls ofTK as knowledge that can be used in 4 research and development (R&D) activities and be integrated in modem innovations. This holds especially true for TK regarding genetic resources, which has been integrated in modem 6 phannaceuticals,s agro-chemicals and seed.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 196 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Twenty five years ago, Bill Stebbins presented the principles of animal psychophysics in an edited volume (Stebbins, 1970) describing an array of modem, creative methodologies for investigating the range of sensory systems in a variety of vertebrate species. These principles included precise stimulus control, a well defined behavioral response, and a rigorous behavioral procedure appropriate to the organism under study. As a generation of comparative sensory scientists applied these principles, our knowledge of sensory and perceptual function in a wide range of animal species has grown dramatically, especially in the field of hearing. Comparative psychoacoustics, i. e. , the study of the hearing capabilities in animals using behavioral methods, is an area of animal psychophysics that has seen remarkable advances in methodology over the past 25 years. Acoustic stimuli are now routinely generated using digital methods providing the researcher with unprecedented possibilities for stimulus control and experimental design. The strategies and paradigms for data collection and analysis are becoming more refined as well, again due in large part to the widespread use of computers. In this volume, the reader will find a modem array of strategies designed to measure detection and discrimination of both simple and complex acoustic stimuli as well experimental designs to assess how organisms perceive, identify and classify acoustic stimuli. Refinements in modem methodologies now make it possible to compare diverse species tested under similar, if not identical, experimental conditions.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 364 pp. Englisch.