crc press jun 2018 (6 Ergebnisse)

Buch. Zustand: Neu. Neuware - Big Data in Omics and Imaging: Integrated Analysis and Causal Inference addresses the recent development of integrated genomic, epigenomic and imaging data analysis and causal inference in big data era. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), genome-wide expression studies (GWES), and epigenome-wide association studies (EWAS), the overall contribution of the new identified genetic variants is small and a large fraction of genetic variants is still hidden. Understanding the etiology and causal chain of mechanism underlying complex diseases remains elusive. It is time to bring big data, machine learning and causal revolution to developing a new generation of genetic analysis for shifting the current paradigm of genetic analysis from shallow association analysis to deep causal inference and from genetic analysis alone to integrated omics and imaging data analysis for unraveling the mechanism of complex diseases.FEATURES - Provides a natural extension and companion volume to Big Data in Omic and Imaging: Association Analysis, but can be read independently. - Introduce causal inference theory to genomic, epigenomic and imaging data analysis - Develop novel statistics for genome-wide causation studies and epigenome-wide causation studies. - Bridge the gap between the traditional association analysis and modern causation analysis - Use combinatorial optimization methods and various causal models as a general framework for inferring multilevel omic and image causal networks - Present statistical methods and computational algorithms for searching causal paths from genetic variant to disease - Develop causal machine learning methods integrating causal inference and machine learning - Develop statistics for testing significant difference in directed edge, path, and graphs, and for assessing causal relationships between two networks The book is designed for graduate students and researchers in genomics, epigenomics, medical image, bioinformatics, and data science. Topics covered are: mathematical formulation of causal inference, information geometry for causal inference, topology group and Haar measure, additive noise models, distance correlation, multivariate causal inference and causal networks, dynamic causal networks, multivariate and functional structural equation models, mixed structural equation models, causal inference with confounders, integer programming, deep learning and differential equations for wearable computing, genetic analysis of function-valued traits, RNA-seq data analysis, causal networks for genetic methylation analysis, gene expression and methylation deconvolution, cell -specific causal networks, deep learning for image segmentation and image analysis, imaging and genomic data analysis, integrated multilevel causal genomic, epigenomic and imaging data analysis.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The biggest challenge in any marketplace is uncertainty. The major changes taking place in world economies, politics, and demographics has raised market uncertainty to its highest level in the past 50 years. However, with new markets opening up in emerging and developing economies, the opportunities have never been better. To compete in this challenging atmosphere, product design/redesign and manufacturing must be integrated to produce better quality products faster and cheaper. Design Synthesis: Integrated Product and Manufacturing System Design provides a conceptual framework and methodologies to do just that.The book explains how to integrate innovative product design with the design of a batch manufacturing system. It covers the technical and social aspects of integration, presents research and best practices, and embeds integration within a framework of sustainable development. It covers the two methods for achieving design synthesis: integration and harmonisation. Product, manufacturing system, and social system architectures are integrated (united or combined to form a whole that is greater than the sum of the parts). The concurrent processes to design the architectures are harmonised (made compatible or coincident with one another).Wide in scope, the book supplies a multi-disciplinary perspective and an extensive discussion on how to maintain integrity during the design process. The authors present research and practices that are difficult or almost impossible to find. They describe the different types of system lifecycles and include guidelines on how to select the appropriate lifecycle for a specific design situation. 382 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book explains physical principles, unique benefits, broad categories, implementation aspects, and performance criteria of distributed optical fiber sensors (DOFS). For each kind of sensor, the book highlights industrial applications, which range from oil and gas production to power line monitoring, plant and process engineering, environmental monitoring, industrial fire and leakage detection, and so on. The text also includes a discussion of such key areas as backscattering, launched power limitations, and receiver sensitivity, as well as a concise historical account of the field's development. 472 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Video Game Law is aimed at game developers and industry professionals who want to better understand the industry or are in need of expert legal guidance. Given the rise in international competition, the increasing complexity of video game features, and the explosive growth of the industry in general, game developers can quickly find themselves in serious trouble, becoming vulnerable to copyright infringement claims, piracy, and even security breaches. Not every video game company has the financial resources to retain in-house counsel-which Video Game Law seeks to address by discussing many of the common pitfalls, legal questions, and scenarios facing the industry. S. Gregory Boyd, Brian Pyne, and Sean F. Kane, the most prominent, sought after, and respected video game attorneys in the country, break down the laws and legal concepts that every game developer and industry professional needs to know in order to better protect their game and grow their company.KEY FEATURES:- Provides a solid understanding of intellectual property (IP) concepts and laws, includingcopyright, trademark, trade secret, and other protections that apply to video games andhow each can be employed to protect a company's unique and valuable IP- Explores cutting edge legal issues that affect the gaming industry, including gambling,virtual currency, privacy laws, the Digital Millennium Copyright Act, tax incentives, andrelevant piracy laws- Provides an overview of legal and privacy vocabulary and concepts needed to navigateand succeed in an industry that is constantly growing and evolving- Provides illustrative examples and legal concepts from the video game industry in everychapter 276 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Our future scientists and professionals must be conversant in computational techniques. In order to facilitate integration of computer methods into existing physics courses, this textbook offers a large number of worked examples and problems with fully guided solutions in Python as well as other languages (Mathematica, Java, C, Fortran, and Maple). It's also intended as a self-study guide for learning how to use computer methods in physics. The authors include an introductory chapter on numerical tools and indication of computational and physics difficulty level for each problem. Readers also benefit from the following features:- Detailed explanations and solutions in various coding languages.- Problems are ranked based on computational and physics difficulty.- Basics of numerical methods covered in an introductory chapter.- Programming guidance via flowcharts and pseudocode.Rubin Landau is a Distinguished Professor Emeritus in the Department of Physics at Oregon State University in Corvallis and a Fellow of the American Physical Society (Division of Computational Physics).Manuel Jose Paez-Mejia is a Professor of Physics at Universidad de Antioquia in Medellín, Colombia. 430 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This practical book deals with the technology of small-power wind turbines as opposed to widely diffused industrial wind turbines and wind farms. It covers the most common wind turbine technologies in the small power segment: horizontal axis both for electrical generation and water pumping, vertical axis of the Darrieus type, and vertical axis of the Savonius type. With each chapter following the same didactic scheme-a theoretical explanation and practical examples showing calculation procedures-it allows anybody with basic technical knowledge to design and build a small wind turbine for any site. A set of simple spreadsheets is available for download, each providing further examples of how to solve specific design problems and allowing the reader to play with changing parameters and see what-if. This simple trial-and-error learning process allows beginners to develop the feeling of the orders of magnitude involved in the design of a small wind power system, its potential advantages on other alternative solutions, and its limitations under some special circumstances. 352 pp. Englisch.