Elsevier science aug 2021 (10 Ergebnisse)

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Health Insurance Systems: An International Comparison offers united and synthesized information currently available only in scattered locations - if at all - to students, researchers, and policymakers. The book provides helpful contexts, so people worldwide can understand various healthcare systems. By using it as a guide to the mechanics of different healthcare systems, readers can examine existing systems as frameworks for developing their own. Case examples of countries adopting insurance characteristics from other countries enhance the critical insights offered in the book. If more information about health insurance alternatives can lead to better decisions, this guide can provide an essential service. 336 pp. Englisch. …

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. 280 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -New Horizons in Evolution is a compendium of the latest research, analyses, and theories of evolutionary biology. Chapters are collected from the international symposium held by the Board of Governors of the University of Haifa to honor Dr. Eviatar Nevo, founder and director of the Institute of Evolution. This book includes material written by top global scientists. Such detailed summaries and recent advances include topics like genomics, epigenetics, evolutionary theory, and the evolution of cancer. This book analyzes evolutionary biology of animals, such as lizards and subterranean mammals. It also discusses agricultural evolution, specifically the vital wheat crop in various climates and locations. Each chapter contributes the most up-to-date knowledge of evolution's role in speciation, adaptation, and regulation. New Horizons in Evolution is a valuable resource for researchers involved in evolution, evolutionary biology, and evolutionary theory. Advanced undergraduate and graduate students in evolutionary biology courses will also find this useful due to the high expertise level and latest knowledge available through this resource. 382 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The rapid increase in microbial resources along with the development of biotechnological methods has revolutionized the field of microbial biotechnology. Genome characterization methods and metagenomic approaches further illustrate the role of microorganisms in various fields of research. Recent Advancement in Microbial Biotechnology: Agricultural and Industrial Approach provides an overview on the recent application of the microorganisms in agricultural and industrial improvements. The purpose of this book is to integrate all these diverse areas of research in a common platform. Recent advancement in Microbial Biotechnology targets researchers from both academia and industry, professors and graduate students working in molecular biology, microbiology and biotechnology. 478 pp. Englisch.…

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Retinal Computation summarizes current progress in defining the computations performed by the retina, also including the synaptic and circuit mechanisms by which they are implemented. Each chapter focuses on a single retinal computation that includes the definition of the computation and its neuroethological purpose, along with the available information on its known and unknown neuronal mechanisms. All chapters contain end-of-chapter questions associated with a landmark paper, as well as programming exercises. This book is written for advanced graduate students, researchers and ophthalmologists interested in vision science or computational neuroscience of sensory systems. While the typical textbook's description of the retina is akin to a biological video camera, the real retina is actually the world's most complex image processing machine. As part of the central nervous system, the retina converts patterns of light at the input into a rich palette of representations at the output. The parallel streams of information in the optic nerve encode features like color, contrast, orientation of edges, and direction of motion. Image processing in the retina is undeniably complex, but as one of the most accessible parts of the central nervous system, the tools to study retinal circuits with unprecedented precision are up to the task. This book provides a practical guide and resource about the current state of the field of retinal computation. 340 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -High-strength materials offer alternatives to frequently used materials for high-rise construction. A material of higher strength means a smaller member size is required to resist the design load. However, high-strength concrete is brittle, and high-strength thin steel plates are prone to local buckling. A solution to overcome such problems is to adopt a steel-concrete composite design in which concrete provides lateral restraint to steel plates against local buckling, and steel plates provide confinement to high-strength concrete. Design of Steel-Concrete Composite Structures Using High Strength Materials provides guidance on the design of composite steel-concrete structures using combined high-strength concretes and steels. The book includes a database of over 2,500 test results on composite columns to evaluate design methods, and presents calculations to determine critical parameters affecting the strength and ductility of high-strength composite columns. Finally, the book proposes design methods for axial-moment interaction curves in composite columns. This allows a unified approach to the design of columns with normal- and high-strength steel concrete materials. This book offers civil engineers, structural engineers, and researchers studying the mechanical performance of composite structures in the use of high-strength materials to design and construct advanced tall buildings. 254 pp. Englisch. …

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Monoclonal antibodies (mAbs) are naturally occurring complex biomolecules. New engineering methods have turned mAbs into a leading therapeutic modality for addressing immunotherapeutic challenges and led to the rise of mAbs as the dominant class of protein therapeutics. mAbs have already demonstrated a great potential in developing safe and reliable treatments for complex diseases and creating more affordable healthcare alternatives. Developing mAbs into well-characterized antibody therapeutics that meet regulatory expectations, however, is extremely challenging. Obstacles to overcome include the determination and development of physiochemical characteristics such as aggregation, fragmentation, charge variants, identity, carbohydrate structure, and higher-order structure (HOS). This book dives deep into mAbs structure and the array of physiochemical testing and characterization methods that need to be developed and validated to establish a mAb as a therapeutic molecule. The main focus of this book is on physiochemical aspects, including the importance of establishing quality attributes such as glycosylation, primary sequence, purity, and HOS and elucidating the structure of new antibody formats by mass spectrometry. Each of the aforementioned quality attributes has been discussed in detail; this will help scientists in researching and developing biopharmaceuticals and biosimilars to find practical solutions to physicochemical testing and characterization. 258 pp. Englisch.…

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and ovarian cancer, immunotherapy to overcome drug resistance, and genetic polymorphisms in gynecologic cancers. Additionally, it discusses ethnic and racial health disparity perspectives and future developments in chemosensitizing activities to reverse drug resistance in gynecologic cancers. It is a valuable resource for cancer researchers, oncologists, clinicians and other biomedical field members who are interested in new approaches to improve chemotherapy outcome in patients with gynecologic cancers. 388 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences. As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis. 736 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. 484 pp. Englisch.…