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Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627038922ISBN 13: 9781627038928
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book focuses on a marvel approach that blends chemistry with forensic science and is used for the examination of controlled substances and clandestine operations. The book will particularly interest forensic chemists, forensic scientists, criminologists, and biochemists. 376 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1489941193ISBN 13: 9781489941190
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The development of neurophysiology, the study of the activity of living nervous tissue, has relied heavily on the techniques of electrophysiology. This emphasis is revealed in volumes 14 and 15 of this series, which show how electrophysiological techniques can be applied to research topics ranging from ion channels to human behavior. Kitai and Park show how cellular neurophysiology can be related to classical neuroanatomy, an important basis for any type of functional analysis. Wonderlin, French, Arispe, and Jones describe new (single channel) and more traditional (whole cell) techniques for studying the role of ion channels in cellular pr- esses, a field that is currently developing very rapidly. An exciting nontraditional approach to the study of cellular electrophysiology is discussed by Hopp, Wu, Xiao, Rioult, London, Zecevic, and Cohen in their paper on optic measurement of membrane pot- tials. Humphrey and Schmidt offer a thoughtful review of the uses and limitations of the technique of recording extracellular unit potentials in the brain. Hoffer presents an introduction to a field that is of great interest but is technically very difficult-the reco- ing from cells and axons in the spinal cord and peripheral nervous system in freely moving animals. An electrophysiological approach to the analysis of the neural mechanisms of normal behavior is presented by Halgren in a wide-ranging review of the field of evoked potentials in humans. 412 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627037721ISBN 13: 9781627037723
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performed in plants. In Plant Epigenetics and Epigenomics: Methods and Protocols, leading scientists in the epigenetics field describe comprehensive techniques that have been developed to understand the plant epigenetic landscape. These include recently developed methods and techniques for analysis of epigenetically regulated traits, such as flowering time, transposon activation, genomic imprinting and genome dosage effects. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoidance of known pitfalls.Authoritative and practical, Plant Epigenetics and Epigenomics: Methods and Protocols seek to aid scientists in the further study of plant epigenetic phenomena using advanced contemporary methods. 256 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1489943609ISBN 13: 9781489943606
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Robert Hall and a panel of expert researchers present a comprehensive collection of the most frequently used and broadly applicable techniques for plant cell and tissue culture. Readily reproducible and extensively annotated, the methods cover culture initiation, maintenance, manipulation, application, and long-term storage, with emphasis on techniques for genetic modification and micropropagation. Many of these protocols are currently used in major projects designed to produce improved varieties of important crop plants. Plant Cell Culture Protocols's state-of-the-art techniques are certain to make the book today's reference of choice, an indispensable tool in the development of new transgenic plants and full-scale commercial applications. 452 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 162703885XISBN 13: 9781627038850
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Blood has long been viewed as a conduit for therapy, stemming from the ancient days of phlebotomy to remove evil humors to the development of successful blood transfusions to replace missing blood components. The identification and characterization of hematopoietic stem cells by Drs. Till and McCulloch revolutionized the field and soon after, non-hematopoietic stem and progenitor cells were characterized from the blood and bone marrow. Some of these cell types and various blood-derived cell lineages are involved in the repair of various types of tissue damage that span the spectrum of medical disorders. The goal of this book is to provide an up-to-date review of the various types of blood-derived cells with regenerative capacity, identify opportunities for intervention by examining specific clinical applications, and recognize the regulatory environment that will encompass future therapies in regenerative medicine. 232 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627039503ISBN 13: 9781627039505
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With a focus on practical patient related issues, Autoimmune Hepatitis: A Guide for Practicing Clinicians serves as a useful practical, and much needed, resource for all those physicians presented with managing patients diagnosed with autoimmune hepatitis, both acutely and over the long term. It provides a basis for clinicians to understand the etiology of the disease, as well as special circumstances where management dilemmas often arise. Emphasis is given to providing management advice of immediate use to clinicians, something not presently offered by other larger general texts. The chapters are written by those with an expertise and training in this field and include the most up to date information. The book will be of great value to Gastroenterologists, Hepatologists, and Internists at all levels who see patients presenting with autoimmune hepatitis. 256 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627039457ISBN 13: 9781627039451
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide. By 2020, COPD is expected to be the fifth leading cause of disability and the third leading cause of death. COPD is associated with significant co-morbid illnesses including cardiovascular disease, pulmonary vascular disease, osteoporosis, depression and thoracic malignancies. In addition, COPD patients often have systemic manifestations of their disease, including peripheral muscle dysfunction, decreased activity levels and nutritional abnormalities, all of which contribute to poor functional status, decreased quality of life and increased health care utilization. Lack of recognition and understanding of the complex interactions of these common co-morbid conditions and systemic effects often contributes to sub-optimal care for patients with COPD. Comprehensive in covering the range of co-morbidities that often accompany COPD, Chronic Obstructive Pulmonary Disease: Co-Morbidities and Systemic Consequences provides a concise, evidence-based review of the problem and its systemic manifestations. All physicians interested in this growing disorder - from subspecialists to primary care providers -will find in this timely and informative title the practical, state-of-the art approaches needed to provide targeted, integrated care for patients with COPD. 300 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1489941231ISBN 13: 9781489941237
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Techniques in the neurosciences are evolving rapidly. There are currently very few volumes dedicated to the methodology - ployed by neuroscientists, and those that are available often seem either out of date or limited in scope. This series IS about the methods most widely used by modern-day neuroscientists and is written by their colleagues who are practicing experts. Volume 1 will be useful to all neuroscientists since it concerns those procedures used routmely across the widest range of s- disciplines. Collecting these general techniques together in a s- gle volume strikes us not only as a service, but will no doubt prove of exceptional utilitarian value as well. Volumes 2 and 3 - scribe current procedures for the analyses of amines and their - tabolites and of amino acids, respectively. These collections will clearly be of value to all neuroscientists working in or contempl- ing research in these fields. Similar reasons exist for Volume 4 on receptor binding techniques since experimental details are p- vided for many types of ligand-receptor binding, including ch- ters on general principles, drug discovery and development, and a most useful appendix on computer programs for Scatchard, nonlinear and competitive displacement analyses. Volume 5 p- vides procedures for the assessment of enzymes involved in biogenic amine synthesis and catabolism. Volumes in the NEUROMETHODS series will be useful to neuro-chemists, -pharmacologists, -physiologists, -anatomists, psychopharmacologists, psychiatrists, neurologists, and chemists (organic, analytical, pharmaceutical, medicinal); in fact, everyone involved in the neurosciences, both basic and clinical. 580 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627037632ISBN 13: 9781627037631
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In DNA Cloning and Assembly Methods, expert researchers in the field detail many of the methods which are now commonly used for DNA cloning and make cloning procedures faster, more reliable and also suitable for high-throughput handling. These include methods and protocols that are based on several mechanisms including type II and IIS restriction enzymes, single stranded annealing, sequence overlap, and recombination.With additional chapters on software programs that are suitable for primer design, a feature crucial for the functionality of the described methods. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, DNA Cloning and Assembly Methods seeks to provide scientist with a valuable and useful resource for wet lab researchers within life sciences. 316 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627037810ISBN 13: 9781627037815
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cell-free protein expression promises to narrow the technological gap between DNA and protein technologies and provide a platform for broad application of synthetic biology principles in the Life Sciences. It is a rapid and high throughput methodology for the conversion of DNA encoded genetic information into protein-mediated biochemical activities. Cell-Free Protein Synthesis: Methods and Protocols brings together the key opinion leaders of cell-free technology development and provides case studies and detailed protocols for the application of cell-free methodology. Chapters cover the main directions in the development of cell-free technologies including several recently developed cell-free systems, as well as a number of applications of cell-free systems ranging from discovery of biofuel enzymes to in vitro assembly of viruses. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Cell-Free Protein Synthesis: Methods and Protocols seeks to serve a wide variety of scientists with its well-honed methodologies. 332 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627037845ISBN 13: 9781627037846
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The application of optical methods for investigating neocortical circuit dynamics has greatly expanded in recent years, providing novel insights into the fascinating world of brain function. Optical Imaging of Neocortical Dynamics presents a guide to these indispensible tools, which cover a broad range of spatiotemporal scales and a large variety of signaling aspects, ranging from voltage changes to metabolic states. This detailed volume specifically explores methods that are applied in experiments on living brains (in vivo) and that relate to functional properties on the spatial scale of cortical circuits. Beginning with an introductory section that focuses on physical fundamentals of optical imaging as well as molecular tools used for in vivo optical imaging and optogenetic control, the book continues with the most relevant methods and their applications to investigate changes in neuronal and glial activity states as well as optical imaging methods probing metabolic states. Written for the Neuromethods series, this volume contains the kind of detail and key implementation advice that ensures successful results in the lab.Practical and easy to use, Optical Imaging of Neocortical Dynamics serves as an ideal guide for researchers who aim to apply these highly valuable tools to their own neuroscientific studies. 308 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627037667ISBN 13: 9781627037662
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Plant taxonomy is an ancient discipline facing new challenges with the current availability of a vast array of molecular approaches which allow reliable genealogy-based classifications. Although the primary focus of plant taxonomy is on the delimitation of species, molecular approaches also provide a better understanding of evolutionary processes, a particularly important issue for some taxonomic complex groups. Molecular Plant Taxonomy: Methods and Protocols describes laboratory protocols based on the use of nucleic acids and chromosomes for plant taxonomy, as well as guidelines for phylogenetic analysis of molecular data. Experts in the field also contribute review and application chapters that will encourage the reader to develop an integrative taxonomy approach, combining nucleic acid and cytogenetic data together with other crucial information (taxonomy, morphology, anatomy, ecology, reproductive biology, biogeography, paleobotany), which will help not only to best circumvent species delimitation but also to resolve the evolutionary processes in play. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Molecular Plant Taxonomy: Methods and Protocols seeks to provide conceptual as well as technical guidelines to plant taxonomists and geneticists. 416 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 162703790XISBN 13: 9781627037907
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Featuring experimental approaches that shed light on the complexity of Ras GTPase biological functions, Ras Signaling: Methods and Protocols contains general overviews and detailed applications of both well-established and recently developed research techniques, including biochemical, biophysical, molecular biology, genetic and behavioral approaches, advanced high resolution fluorescence and electron microscopy imaging and 'omics' technologies. Through this, the detailed volume provides information on expression, post-translational modifications, subcellular localization and dynamics, regulatory mechanisms of upstream and downstream signaling pathways and ultimately, biological activities and functions of Ras GTPases in different model systems, including high and low eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Wide-ranging and authoritative, Ras Signaling: Methods and Protocols serves as an aid for investigators of different backgrounds and interests related to the multiple physiological and pathological functions of the large superfamily of Ras GTPases. 440 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627037780ISBN 13: 9781627037785
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field. From powerful bioinformatic tools tracing the evolution of GPCRs, to methods for the cellular transfection of engineered viruses containing GPCRs, to optogenetic techniques that produce light-activated GPCRs in live mice, what was once science fiction is now science fact. This detailed volume includes sections covering genetic mechanisms, a genetic toolbox for GPCR discovery, as well as genetic aspects of G protein-coupled receptors in health and medicine. Written for the Methods in Pharmacology and Toxicology series, this book contains the kind of key implementation advice that encourages successful results in the lab.Authoritative and easy to use, G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era serves as an ideal guide for researchers aiming to continue our progress in this dynamic and exciting area of study. 436 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627038809ISBN 13: 9781627038805
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Sleep disorders represent a major portion of the chief complaints seen by pulmonologists and other physicians. Sleep apnea and hypopnea syndrome for example, are common disorders with significant adverse health consequences. Sleep apnea is associated with increased cardiovascular mortality, impaired quality of life and increased motor vehicle accidents. In addition, sleep apnea often co-exists with other chronic conditions including obesity, the metabolic syndrome, and tobacco use disorder. Patients with sleep-related conditions often present with non-specific complaints that require a broad and detailed knowledge of the wide range of sleep disorders. In Essentials of Sleep Medicine: An Approach for Clinical Pulmonology, a concise, evidence-based review of sleep medicine for the pulmonologist is presented. Providing a focused, scientific basis for the effects of sleep on human physiology, especially cardiac and respiratory physiology, chapters also outline a differential diagnosis for common sleep complaints and an evidence-based approach to diagnosis and management. This includes a review of the current standards of practice and of emerging technology and unresolved issues awaiting further research. Each chapter includes a summary of current research and outlines future research directions and issues. In all, Essentials of Sleep Medicine: An Approach for Clinical Pulmonology provides a clear diagnostic and management program for all the different sleep disorders, with a major focus on respiratory disorders of sleep, and includes key points and summaries. Developed by an international group of renowned authors, Essentials of Sleep Medicine: An Approach for Clinical Pulmonology is an invaluable resource for pulmonologists, respiratory care practitioners, polysomnographic technologists, graduate students, clinical researchers, and other health professionals seeking an in-depth review of sleep medicine. 428 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 162703594XISBN 13: 9781627035941
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Handbook of Environmental Engineering series is an incredible collection of methodologies that study the effects of pollution and waste in their three basic forms: gas, solid, and liquid. This exciting new addition to the series, Volume 15: Modern Water Resources Engineering , has been designed to serve as a water resources engineering reference book as well as a supplemental textbook. We hope and expect it will prove of equal high value to advanced undergraduate and graduate students, to designers of water resources systems, and to scientists and researchers. A critical volume in the Handbook of Environmental Engineering series, chapters employ methods of practical design and calculation illustrated by numerical examples, include pertinent cost data whenever possible, and explore in great detail the fundamental principles of the field. Volume 15: Modern Water Resources Engineering, provides information on some of the most innovative and ground-breaking advances in the field today from a panel of esteemed experts. 888 pp. Englisch.
Verlag: Humana Press Jan 2014, 2014
ISBN 10: 1627039171ISBN 13: 9781627039178
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the last 30 years it has become clearly evident that oxidative stress and free radical biology play key roles in carcinogenesis, cancer progression, cancer therapy, and normal tissue damage that limits treatment efficacy during cancer therapy. These mechanistic observations have led to the realization that free radical biology and cancer biology are two integrally related fields of investigation that can greatly benefit from cross fertilization of theoretical constructs. The current volume of scientific papers was assembled under the heading of Oxidative Stress in Cancer Biology and Therapy in order to stimulate the discussion of how the knowledge gained in the emerging field of oxidative stress in cancer biology can be utilized to more effectively design interventions to enhance therapeutic responses while causing fewer treatment limiting complications. The chapters contained in this volume provide highly informative emerging perspectives on how that selective enhancement of oxidative stress in cancerous tissues can be used as a target for enhancing therapeutic outcomes as well as how selective inhibition of oxidative stress could spare normal tissue damage and inhibit carcinogenesis. In this regard, the book represents an outstanding resource for both basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy. 480 pp. Englisch.