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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Five years ago, a new system of classification of the various types of diabetes was proposed. This publication provides an inte grated picture of the latest information on the similarities and dissimilarites of two types of diabetes. It contains contributions from morphologists, physiologists, biochemists, immunologists, pathologists, geneticists, clinicians and epidemiologists. In the first section, the basis for the present classification and its limitations are discussed. In addition, there is a discussion of gestational diabetes and heterogeneity of some sub-classes of diabetes. The next section deals with genetics and immunology. The third section discusses abnormalities of insulin secretion and act ion on both the receptor and post . . . receptor levels. The role of gastrointestinal peptides in Type I and Type II diabetes is also considered. In the last section, both types of diabetes are compared with respect to diabetic complications. The closing sec tion summarizes the present status and offers a stimulating view of future development. We hope that this book will be a useful source of information for both researchers and practicing clinicians. M. Vranic G. steiner C. H. Hollenberg v ACKNOWLEDGEMENTS The symposium from which this volume arose (June 28-29, 1984) was organized by the Banting and Best Diabetes Centre, University of Toronto. We would like to express our appreciation to the following sponsors: Ames Educational Institute, Ayerst Laboratories, Becton Dickinson Canada Inc. , Canadian Soft Drink Association, Connaught Laboratories Limited, Connaught Novo Ltd. , Eli Lilly Canada Inc. 364 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -How are we to understand the complex forces that shape human behavior A variety of diverse perspectives, drawing upon studies of human behavioral ontogeny, as well as humanity's evolutionary herit age seem to provide the best likelihood of success. It is in the attempt to synthesize such potentially disparate approaches to human develop ment into an integrated whole that we undertake this series on the Genesis of Behavior. In many respects, the incredible burgeoning of research in child development the last or like a lines over decade two seems thousand of inquiry spreading outward in an incoherent starburst of effort. The need exists to provide, on an ongoing basis, an arena of discourse within which the threads of continuity between those diverse lines of research on human development can be woven into a fabric of meaning and understanding. Scientists, scholars, and those who attempt to translate their efforts into the practical realities of the care and guidance of infants and children are the audience that we seek to reach. Each requires the opportunity to see-to the degree that our knowledge in given areas permits-various aspects of development in a coherent, integrated fashion. It is hoped that this series-by bringing together research on infant biology; developing infant capacities; animal models, the impact of social, cultural, and familial forces on development, and the distorted products of such forces under certain circumstances-will serve these important social and scientific needs. 444 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Throughout the last decade, the field of clinical psychology has expanded dramatically. Clinical psychologists are involved in the treatment and research of a wider range of problems and disorders than they have ever been before. Evidence has been rapidly ac cumulating regarding the role of psychological variables and stress in the etiology and maintenance of a range of medical and psychiatric disorders. New models of psy chotherapy have been developed and refined, and the specific efficacy of psychother apeutic interventions for an increasing number of disorders (or sUbtypes of disorders) has been documented. However, concurrent with research that demonstrates the impact of psychosomatic factors in various disorders and the efficacy of psychological or psychosocial interven tions, dramatic progress has been made with regard to the investigation of biological factors that may mediate certain disorders. That physical factors may underlie many in stances of psychiatric illness has been repeatedly demonstrated. Also, the efficacy of so matic treatments for different disorders, or for subtypes of disorders, has been reported with increasing methodological rigor. 396 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In Number 20 of Modern Aspects of Electrochemistry, we present chapters whose organization is typical for the series: They start with the most fundamental aspects and then work to the more complex. Thus, Jerry Goodisman gives us an interesting contribution on a subject in which he is one of the pioneers, the electron overlap contribution to the double layer potential difference. Closely related to this theme, but not always imbued with knowledge ofit, is the electron transfertheory, treated in this volume by the experienced author A. M. Kuznetsov ofthe Frumkin Institute. H. P. Agarwal is a well-known figure in the field of faradaic rectification, which he originated, and he now teils us about the more recent thinking in the field. On the other hand, Hector D. Abruna comes relatively new to us, and his field, that of X-ray interactions with electrodes, is new, too, but probably augers the trend for the future. The photoelectrochemical reduction of CO2 , described here by Isao Taniguchi from Kumamoto University, is a subject which will have much practical importance as the greenhouse effect continues. Finally, alu mi nu m in aqueous solutions and the physics of its anodic oxide is a subject which seems ever with us, and is described in its latest guise by Aleksandar Despie and Vitaly P. Parkhutik. 536 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Whenever the coronary flow is inadequate to provide enough oxygen to meet the energy demands of the tissue, the heart becomes ischemic. Manifestations of myocardial ischemia include depression in contractile activity, changes in metabolic pattern, abnormalities in ultrastructure, and alterations in membrane potential. Ischemic changes during the early phase are reversible but as the period of ischemia is extended, the injury becomes irreversible. The transition from reversible to irreversible ischemic injury is usually associated with some membrane defects. It is worthwhile to consider that the irreversible damage to the ischemic myocardium occurs when the sarcolemmal membrane is altered in suoh a way that it would promote 2 a net gain of ca + in the cardiac cell upon reinstitution of blood flow. Suoh a lesion could result when mechanisms for the entry as well as removal 2 of ca + from the myocardial oell become defective. In this regard, 2 depression of the sarcolemmal ca + pump would favour the oocurrenoe of 2 intracellular ca + overload. Furthermore, inhibition of the Na+-K+ pump would lead to elevation of myoplasmic Na+ which oould then increase the 2 2 intracellular concentration of ca + through the sarcolemmal Na+-ca + exchange mechanism. In faot recent studies have revealed an inhibition of 2 the sarcolemmal Na+-ca + exchange mechanism in the ischemic heart and this 2 change could also contribute towards the occurrence of intracellular ca + 2 overload. 372 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It was seven years ago this month when I had the pleasure of writing the Foreword to the Proceedings of the Eighth Conference on Thermal Conductivity hosted by TPRC/ Purdue University in 1968. Since then this Conference has developed to the point where one can say it has just entered a new phase. At its meeting in June 1975, the Board of Governors of the International Thermal Conductivity Conferences passed a resolution which formalizes two main policies that were felt to be desirable for a number of years, A key item of the resolution was for CINDAS/Purdue University to become the permanent Sponsor of the Conferences and in this capacity assist the Conferences in all matters which will result in the effective implementation of its goals and mission. In short, CINDAS will serve as a home base for the Conferences thus providing continuity and a permanent point of contact. CINDAS/Purdue University is pleased to accept this respons ibility as it is well within its mission to promote the advancement and dissemination of knowledge on thermophysica! properties of matter. A second important aspect of the Conference resolution was the establishment of a policy to publish the Proceedings of future conferences on a continuing and uniform basis effective with this, the Fourteenth Conference. 584 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The techniques of tissue culture were introduced at the beginning of this century. They have become more and more popular as it is realized that they are not as difficult or as esoteric as some early protagonists liked to maintain. Most of the work performed with culture methods has simply concerned cell growth and survival. Biologists have long used culture approaches to provide a simple system in which to study cell division and multiplication. Any pharmacology done on cultured tissue was largely toxicological or as part of a screening programme for poten tial anti-cancer drugs. In the last decade there has been a great increase in the use of excitable cells in tissue culture. Nerves and muscles from a wide variety of sources can maintain their highly differentiated properties in culture. Such cultures offer an attractive preparation for use in physiological and pharmacological investigations. Consequently, a vast amount of work has been produced, and this book is an attempt to review it. It is hoped that this will introduce physiologists and pharmacologists to the potential of culture methods for their experiments and also indicate to more traditional tissue culture users further possible areas of interest. By being more comprehensive in scope and by trying to concentrate largely on drug actions, I hope that the present volume usefully extends the treatment of the subject begun earlier in the excellent works by Crain (1976) and Nelson and Lieberman (1981). 268 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Gastric secretions contain hydrogen ions at a concentration that is more than one million times higher than their intracellular concentration. This phenomenal gradient as well as the demonstrated ability of gastric juice to digest tissues has motivated clinicians and investigators alike to emphasize acid secretion and acid ablation in studying the pathogenesis and therapy of peptic ulcer disease. Conse quently, over the past 150 years, we have made considerable progress in under standing the mechanisms and regulation of acid secretion by the stomach. Not surprisingly, therapy for both peptic disease and mucosal injury has also been predominantly directed at either neutralizing acid or suppressing its production. During the past 10 years, attention has been focused on factors other than acid in the genesis and therapy of ulcer disease. Work done worldwide demon strated that acid hypersecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas troduodenal mucosa is normally protected by a complex series of events includ ing mucus and bicarbonate secretion, cell renewal, surface mucosal restitution, and preservation of the microvasculature and mucosal proliferative zone. 244 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -What are plant growth regulators In the title, and throughout the text, we have adopted this expression to describe a population of endogenous molecules and synthetic compounds of similar structure that are be lieved to play important roles in the regulation of plant differentiation and development. For many years, plant scientists have endeavoured to understand the nature and action of plant growth regulators and, as a result, an awesome quantity of written material now exists describing these chemicals and their effects. In this book we have aimed to distil this wealth of information into a more digestible form, and in particular we have focused our attention on a critical appraisal of the literature. The past few years have witnessed a change of emphasis in plant growth regulator research, which has been fuelled by powerful new techniques in molecular and cell biology. Today we can do more than just apply a plant growth regulator and quantify its effects; we have reached an exciting crossroads where plant scientists, molecular bio logists and chemists can pool their expertise and apply it to the out standing problems in this area. The combination of these three disciplines within the book is clear evidence of this. In keeping with a volume of this size, we have assumed that the reader has a sound knowledge of plant physiology and biochemistry. However, wherever possible, we have highlighted useful reviews which provide background information, along with recent publications that have contributed significantly to the literature. 204 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -to the Second Edition RESEARCH INTO MEMBRANE-ASSOCIATED PHENOMENA HAS EXPANDED VERY greatly in the five years that have elapsed since the first edition of Biological Membranes was published. It is to take account of rapid advances in the field that we have written the present edition. There is now general acceptance of the fluid mosaic model of membrane structure and of the chemiosmotic interpretation of energetic processes, and our attention has shifted from justifying these ideas to explaining membrane functions in their terms. Much more information has become available concerning the role of the plasma membrane in the cell's recognition of and response to external signals, and this is reflected in the increased coverage of these topics in the book. The general form of the book remains the same. As before, a list of suggested reading, sub-divided by chapter, is provided and this has been expanded to include a greater proportion of original papers. The book is still primarily designedas an advanced undergraduate text and also to serve as an introduction for post-graduate workers entering the field of membrane research. We have taken cognizance of the comments of many reviewers, colleagues and students on the first edition and thank them for their contributions. In particular we wish to acknowledge our colleagues R. Eisenthal, G. D. Holman, D. W. Hough, and A. H. Rose. Dr. C. R. 300 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains fifteen papers by invited participants delivered at the NATO International Workshop on Coping and Health held March 26 through March 30, 1979, at the Rockefeller Foundation's Bellagio study and Conference Center, Bellagio, Italy. The editors of the book were co-directors of the workshop as well as participants. The conference was a small conference consisting of only 20 scientists and was designed to be an intensive period of exchange of ideas dealing with a range of topics varying from experimental models of coping through coping and its psychosomatic implications. The exceptional beauty of the Bellagio Study and Conference Center, the hospitality of the staff at the Conference Center as well as the support of the administrative staff of the Rockefeller Foundation, combined with the intensity and enthusiasm of the participants made the conference a most memorable one for those who attended it. A special thanks is in order for the help and assistance of Dr. B. A. Bayraktar, Executive Officer of Human Factors Program, Scientific Affairs Division, NATO, and Miss Susan Garfield, Program Director of the Rockefeller Foundation. Needless to say, without their participation and help at all points in the organization and planning of this conference, the conference would not have occurred. 376 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book outlines many of the techniques involved in materials development and characterization for photoelectrochemical (PEC) - for example, proper metrics for describing material performance, how to assemble testing cells and prepare materials for assessment of their properties, and how to perform the experimental measurements needed to achieve reliable results towards better scientific understanding. For each technique, proper procedure, benefits, limitations, and data interpretation are discussed. Consolidating this information in a short, accessible, and easy to read reference guide will allow researchers to more rapidly immerse themselves into PEC research and also better compare their results against those of other researchers to better advance materials development.This book serves as a 'how-to' guide for researchers engaged in or interested in engaging in the field of photoelectrochemical (PEC) water splitting. PEC water splitting is a rapidly growing field of research in which the goal is to develop materials which can absorb the energy from sunlight to drive electrochemical hydrogen production from the splitting of water. The substantial complexity in the scientific understanding and experimental protocols needed to sufficiently pursue accurate and reliable materials development means that a large need exists to consolidate and standardize the most common methods utilized by researchers in this field. 136 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is derived from a Symposium held at the 190th National American Chemical Society Meeting, which was held in the Fall of 1985, in Chicago, and was sponsored by the Division of Polymeric Materials: Science & Engineering. This Symposium was, in turn, a follow-up on an earlier one held in Houston, TX, in the Spring of 1980, which was pub lished as the book Biomedical and Dental Applications of Polymers [Plenum Press, New York, 1981]. In that earlier book, our opening Preface passage quoted King David, 1 will praise Thee; for I am fearfully and made . -- - (Psalm 139:14). As we noted five years ago, sickness wonderfully of many types does occur in our wonderfully made bodies, but much human suffering can be aided by biomedical polymers. That earlier book con sidered much of the fantastic progress that had been made in biomedical polymers during the previous quarter century and brought many of these topics up to date. That Symposium, and book, noted that much help was available for the varied afflictions and problems that sometimes beset, and upset, our God-given bodies, and the promise of new and important advances was held out as a shining ray of hope amidst the gloom of sickness and affliction. The present volume is an update on the advances that have occurred since the 1981 book and sets the stage for even greater advances in the future. 420 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is the most comprehensive survey of the mathematical life of the legendary Paul Erdös (1913-1996), one of the most versatile and prolific mathematicians of our time. For the first time, all the main areas of Erdös' research are covered in a single project. Because of overwhelming response from the mathematical community, the project now occupies over 1000 pages, arranged into two volumes. These volumes contain both high level research articles as well as key articles that survey some of the cornerstones of Erdös' work, each written by a leading world specialist in the field. A special chapter 'Early Days', rare photographs, and art related to Erdös complement this striking collection. A unique contribution is the bibliography on Erdös' publications: the most comprehensive ever published. This new edition, dedicated to the 100th anniversary of Paul Erdös' birth, contains updates on many of the articles from the two volumes of the first edition, several new articles from prominent mathematicians, a new introduction, more biographical information about Paul Erdös, and an updated list of publications.The first volume contains the unique chapter 'Early Days', which features personal memories of Paul Erdös by a number of his colleagues. The other three chapters cover number theory, random methods, and geometry. All of these chapters are essentially updated, most notably the geometry chapter that covers the recent solution of the problem on the number of distinct distances in finite planar sets, which was the most popular of Erdös' favorite geometry problems. 584 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is the most comprehensive survey of the mathematical life of the legendary Paul Erdös (1913-1996), one of the most versatile and prolific mathematicians of our time. For the first time, all the main areas of Erdös' research are covered in a single project. Because of overwhelming response from the mathematical community, the project now occupies over 1000 pages, arranged into two volumes. These volumes contain both high level research articles as well as key articles that survey some of the cornerstones of Erdös' work, each written by a leading world specialist in the field. A special chapter 'Early Days', rare photographs, and art related to Erdös complement this striking collection. A unique contribution is the bibliography on Erdös' publications: the most comprehensive ever published. This new edition, dedicated to the 100th anniversary of Paul Erdös' birth, contains updates on many of the articles from the two volumes of the first edition, several new articles from prominent mathematicians, a new introduction, and more biographical information about Paul Erdös with an updated list of publications.The second volume contains chapters on graph theory and combinatorics, extremal and Ramsey theory, and a section on infinity that covers Erdös' research on set theory. All of these chapters are essentially updated, particularly the extremal theory chapter that contains a survey of flag algebras, a new technique for solving extremal problems. 628 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Hyatt Regency Hotel, Columbus, Ohio was the venue for the 1995 Cryogenic Engineering Conference. The meeting was held jointly with the International Cryogenic Materials Conference. Jim Peeples, of CVI, Inc., was conference chairman. Columbus is the home of the Battelle Memorial Institute, a pioneer in cryogenic materials development; the home of CVI, Inc., and Lake Shore Cryotronics, Inc., two leading manufacturers of cryogenic equipment; and it is the home of Ohio State University, where research on liquid helium has long been conducted. The program consisted of 315 CEC papers, nearly the same number as for CEC-91. This was the second largest number of papers ever submitted to the CEC. Of these, 252 papers are published here, in Volume 41 of Advances in Cryogenic Engineering. Once again the volume is published in two books. This volume includes a number of photographs taken during the awards lunch on July 20, 1995. Photographs have often been taken during the conferences, but they have never been used. The pictures are of the awardees, the conference chairs, and the organizers. They are distributed through out the books on pages that would otherwise have been blank. The pictures can be found on the following pages: 28, 232, 334, 536, 640, 826, 990, 1032, 1202, 1462,1682,1888, and 1994. 1072 pp. Englisch.