springer chapman and hall crc okt 2011 (182 Ergebnisse)

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book originates from the NATO Advanced Study Institute on Synthesis and Analysis Methods for Safety and Reliability Studies held at Sogesta Conference Centre, Urbino, Italy, 3-14 July 1978. The Institute, co-directed by Prof. E.J. Henley and Dr. G. Volta, was attended by 67 persons from twelve countries. The focus of the Institute was on theoretical and applied aspects of reliability and risk analysis methodologies. The Institute was composed of lectures, workshops and gu~ded discussions. From the large quantity of written material that was used and produced during the Institute, a number of papers introducing the most relevant research results and trends in the field have been selected. The papers have been edited, partly rewritten and rearranged in order to obtain in the end an integrat ed exposition of methods and techniques for reliability analysis and computation of complex systems. The book is divided into four sections which correspond to fairly homogeneous areas from a methodological point of view. Each section is preceded by an introduction prepared by the Editors which aims at helping the readers to put in perspective and appre ciate the contribution of each paper to the subject of the section. 476 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume constitutes the proceedings of the 1983 Denver Conference on Applications of X-ray Analysis and is the 27th in the series. The conference was held jointly with the American Crystal lographic Association at Snowmass Resort, Colorado, from August 1 to 5, 1983. The papers appearing in this volume are only from pre dominantly Denver Conference (DC) sessions and from joint DC/ACA sessions. The early plans for holding a joint conference were initiated some three years ago by Q. C. Johnson of Lawrence Livermore Lab, J. B. Cohen of Northwestern University and P. K. Predecki of the University of Denver and were eventually brought to fruition by a jOint organizing committee consisting of: O. P. Anderson, Colorado State University (ACA) , D. E. Leyden, Colorado State University (DC), R. D. Witters, Colorado School of Mines (ACA) and P. K. Predecki (DC). We take this opportunity to thank the committee members and the early planners for their vision, ingenuity and hard work without which the conference would not have materialized. There was no plenary session in 1983, instead a number of special sessions were organized and chaired by various individuals. 600 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Historically, the development of biological science has proceeded from the anatomy to the physiology of particular systems. Knowledge about neurotransmitters in the brain has evolved from the discovery of the compounds per set through the elucidation of their biosynthetic and degradative pathways, and finally to the current focus, the regulation of these processes. Regulation in a biological system implies the capacity to respond to perturbations. The introduction of standard and speci fiable disturbances in a biological system followed by examination of the mechanisms involved in response, i.e. that dampen and/or cancel the induced changes, has proved to be a successful way to elucidate regulatory mechanisms. Psychotropic drugs have been most useful to students of regula tory mechanisms in that calvarial prisoner, the brain, for they allow prospective manipulation of variables like dosage and time. Those of us interested in the biological substrata of behavior are especially excited that disturbance induced by drugs leaves the organism intact and behaving, and we can observe behavioral correlates. The pharmacological strategy is, of course, not unique to brain scientists. The relationship between psychotropic drugs and our emerging knowledge of neurotransmitter regulation is, for example, akin to the development of anticancer agents in company with the uncovering of many mysteries of molecular biology. 332 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume of Molecular Biology of Hematopoiesis is dedicated to John W. Adam son, M. D. , Tadamitsu Kishimoto, M. D. , Robert C. Gallo, M. D. , Arthur W. Nienhuis, M. D. , and Franco Mandelli, M. D. , for their contributions in developing an overall view of the state-of-the-art knowledge in the field of hematopoiesis. Richard Champlin, among other renowned clinicians, presented updated information on stem cells and T-cell depletion for bone marrow transplant. A clinical update on thrombopoietin was presented by Pamela Hunt of Amgen and by Kenneth Kaushansky. Arthur Nienhuis' and Katherine Turner's contribu tions to our current knowledge and advances in the fields of growth factors and gene transfer were also recognized during the 9th Symposium on Molecular Biology of Hematopoiesis in Genoa. The chapters cover such diverse areas as preclinical and clinical updates on growth factors and positive and negative regulatory molecules. 'Advances in Leukemia: Mechanism and Treatment by Interferon' was presented by Professor Sante Tura. Readers will find presentation of exciting advances that have occurred in the area of hematopoiesis. The elucidation of gene structures of key growth factor proteins such as IL-12 and IL-II will lead to new insights and new approaches in understanding the regulation of hematopoiesis, as well as application of new growth factors. 736 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Eleventh Biennial Polymer Symposium of the Division of Polymer Chemistry, Incorporated of the American Chemical Society was held November 20-24, 1982 at -the Cerromar Beach Hotel, Dorado Beach, Puerto Rico. The theme of the meeting was 'High Performance Polymers. ' On this occasion Professor Herman F. Mark received the Fourth Division of Polymer Chemistry Award for his outstanding achievements and his unique missionary role in the development of Polymer Chemistry. Professor Mark was the premier organizer of many important firsts in polymer chemistry, to name just a few - the first polymer journal, the pre-eminent Journal of Polymer Science; the first U. S. academic center of Polymer Science at the Brooklyn Polytechnic Institute which led to a long procession of eminent polymer scientists; the 'High Polymer' Monograph series. In the Division of Polymer Chemistry, he was the first secretary-treasurer and chairman in 1955 -- A detailed biography follows along with Professor Mark's reminiscences on the Early Days of Polymer Science, the topic of his Award lecture. It was indeed a pleasure and ultimate honor to be the Chairman and organizer of the technical program of this Symposium. The fourteen invited lectures are given herein. I have tried and believe succeeded in presenting important current research by leading workers on High Performance Polymers. 476 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -reached full definition in the 1940s by Kempner diet. The important role of adrenal aldosterone and associates in demonstrating the beneficial ef secretion in supporting human hypertension is now fects of a low salt rice diet for treating hypertensive well recognized as are the beneficial effects of patients. It became apparent that the value of rice blockade, especially in low-renin patients who ex was wholly related to its sodium content. A rice hibit inappropriate or absolute excesses of aldoste diet, or any other stringent low sodium diet, rone secretion. Further definition of the more sub greatly improves or completely corrects the hyper tle participation of aldosterone and of the factors tension of about ~ or so of all patients with essen that control aldosterone secretion in hypertensive subjects are promising areas for further research. tial hypertension. However, what is often forgotten is that little or no benefit accrues to the remaining THE NERVOUS SYSTEM majority of patients. Parallel studies of animal models has demon Besides the endocrine and excretory functions of strated the amplifying effect of a high sodium diet the kidney and the influence of dietary sodium on blood pressure and vice versa. Strains of rats and of aldosterone secretion, there has been long were developed which are especially sensitive to standing agreement about the important role of the pressor effects of a high sodium diet. In a way, the nervous system in blood pressure control. 672 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Tension' is an internationally recognized word. Its omnI presence in our public media--in our newspapers, on TV, in magazines, and on radio--as well as in our everyday conversations indicate that we are well aware of the problems of over-tenseness. Pulp news papers and magazines increase their sales with promises of quick relief for tension problems. Business executives complain at the end of the day of being 'uptight', and often accept a hotel chain's invitation to 'unwind' at their bar. Soap operas attract large audiences, in part capitalizing on tension problems--irritable ar guments between husband_ and wife seem interminable! Indeed, the entire world is aware of the need to control ten sions. Such widespread needs invite varied 'solutions', with the most attractive appearing ones offering promises of quick and easy cures. The market for tension reduction has been exploited in numer ous ingenious ways for centuries but I think never more than today. People with serious tension disorders often eagerly seize promises of easy relief, regardless of cost. Those who suffer headaches, spastic colon, essential hypertension, back pains, phobias and general anxiety are especially sensitized to tension disorders and potential cures. The American Association for the Advancement of Tension Control is dedicated to the elimination of tension problems through a two pronged attack: through the immediate technological application of tension control principles that now exist, and by encouraging scientific research to further develop our methods. 336 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The magnitude of the threat to the human genetic material posed by environmental agents has not as yet been fully determined. Never theless, the potential hazards of many chemicals have been identi fied by studies on lower organisms. However, too little is known regarding the comparability or lack of it between the metabolic pathways available in such organisms and those in man. Although at present there is great public concern for what is considered by some as the excessive use of laboratory animals in toxicological testing, it seems clear that the usage of mammalian systems may be deemed necessary. It has been proposed that cell culture systems might suffice to meet this need, however, such approaches cannot match the complexity of physiological occurances that are present in the intact animal. For studies of genetic effects, some non-invasive human test systems are presently available. These do not, however, meet the re quirements for extensive laboratory studies. In order to assess the risks to humans of environmental factors such laboratory investiga tions are essential. Therefore, for the forseeable future reliance on experiments using laboratory animals will be necessary. This Volume, which contains the proceedings of a workshop which was held at the National Institute of Environmental Health Sciences, March 29-31, 1982, explores the existing methodologies and their utility for risk estimations. It covers the most well developed human systems, as well as the most widely used animal tests. 352 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book records the proceedings of a joint U.S.-Japan symposium on the chem istry, biochemistry, and biology of bleomycin, an antitumor antibiotic shown to be effective therapeutically against, eg, squamous cell carcinomas, Hodgkin's lymphoma, and testicular tumors. Several important and previously unreported observations were presented and the status of experimental work in the United States and Japan was reviewed; a summary and interpretation of the scientific presentations at the meeting has been prepared by the editor and is included as the first contribution in this volume. In addition to the symposium contributions, an experimental section has been included at the end of the book dealing with practical methods for the fractiona tion, modification, and assay of bleomycin. It is hoped that this section will facilitate progress in this area of scientific endeavor. The symposium from which this book is derived was organized by Drs. Umezawa, Takita, and Hecht and supported financially by the National Science Foundation, the National Cancer Institute, and the Japan Society for the Promotion of Science. S. M. Hecht v Contents Status Reports Summary of the Bleomycin Symposium. S. M. HECHT . 1 Advances in Bleomycin Studies. H. UMEZAWA . , 24 Review of the Structural Studies on Bleomycin. T. TAKITA . . . . . . . . . . 37 . Synthetic and Biosynthetic Studies Studies on the Total Synthesis of Bleomycin. S. M. HECHT, D. 1. BURLETT, Y. MUSHIKA, Y. KURODA, and M. D. LEVIN . 48 A Synthetic Approach to the Pyrimidine Moiety of Bleomycin. 368 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book contains the cm1'1plete set of papers pres- ted at the Third United States-Japan Science Cooperation SeITlinar on the Subj ect of Holographic IITlaging and Infor ITlation Processing, held at Hawaii, January 8 to 13, 1973, under the joint sponsorship of the National Science Foun dation and the Japan Society for the ProITlotion of Science. The papers present the latest advances and state of the art in areas ranging froITl ultrasonic holography, radar and sonar to ultrasonic pulse-echo iITlaging, acoustic ITlicro scopy and iITlage proces sing in bioITledical engineering. COITlputer proces sing of ultrasonic iITlages is extensively discussed. Several papers describe the reITlarkable appli cations of ultrasonics in ITledical diagnostics. One describes new features in R&D ITlanageITlent that are particularly rele vant to the field as a result of recent changes in national science and technology policies. We also present the ITlost recent advances in the powerful ITlethods of iITlage iITlprove ITlent (sharpening, deblurring) which have been ITlade poss ible with the aid of holograITls used as cOITlputing eleITlents; the holographic iITlage deblurring ITlethod is capable of an astonishing iITlproveITlent of iITlages that are still unattainable with even the ITlost powerful digital cOITlputer ITlethods. The book follows the 1971 PlenuITl Publishing COITlpany book, 'Applications of Holography', which cOITlprised the papers presented at the Second U. S. -Japan SeITlinar held in Wash ington, D. C. , October 13 to 18, 1969. 660 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The fields of X-Ray Spectroscopy in Atomic and Solid State Physics have undergone spectacular growth, sometimes rather anarchic, during the past decade. The old mold of X-ray spectroscopy has been burst, and this ASI provided an in-depth exploration of theory and recently developed techniques; however, some work still needs to be done to create a new frame and reduce anarchy in the field. The purpose of this Institute was to gather atomic and solid state physicists working in theoretical and new experimental techniques recently developed. The lectures were concerned with, among others, the following fields: theory of X-ray near-edge structure, XPS and AES with conventional and synchrotron radiation sources, PIXE, EXAFS, SEXAFS, XRF, SXS, and molecular spectroscopy. The Institute considered in detail some of these experimental tech niques and the pertinent theoretical interpretations by selecting an important list of lectures which summarize the scientific contents of the ASI. The truly international character of this NATO ASI, its size, and the high quality of the lecturers contributed to make this school a very fruitful scientific meeting. Two to four general lectures were given each working day and three afternoons were reserved for presentation of current work in the form of posters. We think that these poster presentations reflect the current research work of the participants. 436 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since the 1950s shock compression research contributed greatly to scientific knowledge and industrial technology. As a result, for example, our understanding of meteorite impacts has substantially improved, and shock processes have become standard industrial methods in materials synthesis and processing. Investigations of shock-compressed matter involve physics,electrical engineering, solid mechanics, metallurgy, geophysics and materials science. The description of shock-compressed matter presented here, which is derived from physical and chemical observations, differs significantly from the classical descriptions derived from strictly mechanical characteristics. This volume, with over 900 references, provides an introduction for scientists and engineers interested in the present state of shock compression science. 236 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents an account of the NATO Advanced Study Institute on 'Energy Transfer Processes in Condensed Matter', held in Erice, Italy, from June 16 to June 30, 1983. This meeting was organized by the International School of Atomic and Molecular Spectroscopy of the 'Ettore Majorana' Centre for Scientific Culture. The objective of the Institute was to present a comprehensive treatment of the basic mechanisms by which electronic excitation energy, initially localized in a particular constituent or region of a condensed material, transfers itself to the other parts of the system. Energy transfer processes are important to such varied .fields as spectroscopy, lasers, phosphor technology, artificial solar energy conversion, and photobiology. This meeting was the first encounter of this sort entirely dedicated to this important topic. A total of 65 participants came from 47 laboratories and 16 nations (Belgium, Czechoslovakia, F.R. of Germany, France, Greece, India, Ireland, Israel, Italy, The Netherlands, Poland, Portugal, Switzerland, Turkey, United Kingdom, and the United States of A America). The secretaries of the course were: Ms. Aliki Karipidou for the scientific aspects and Mr. Massimo Minella for the admini strative aspects of the meeting. 728 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The very first international working discussion on slow infections of the nervous system was entitled 'Slow, Latent, and Temperate Virus Infec tions' and was held at the National Institutes of Health (NIH) in December 1964. The primary impetus was the discovery and investigation of kuru in New Guinea by D. Carleton Gajdusek, M. D. This working discussion brought together investigators in human and veterinary medicine, virolo gists, microbiologists, and neuropathologists actively engaged in laboratory work with viruses that illustrated properties of latency, masking, slowness, or temperateness, with emphasis on subacute and chronic neurologic dis eases of unknown etiology. In the Preface to the monograph of published papers presented at the working discussion, Gajdusek and Gibbs wrote the following: After microbiology had given solution to the etiology of most acute infections of the central nervous system and after fungi and bacteria had been incriminated in impor tant chronic disorders of the nervous system such as torula and tuberculosis men ingitis, we have been left, in neurology, with a wide range of subacute and chronic affections of the central nervous systems of unknown etiology. Some of these diseases, still listed as idiopathic, are among the most prevalent afflictions of the central nervous system. Many others with familial patterns of occurrence do not yet have their basic pathogenesis or underlying metabolic defect elucidated, although we tend to think of them as genetically mediated. 444 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is a compilation of papers presented at the International Workshop on the Theory and Applications of the Cluster Variation and Path Probability Methods, held in the city of San Juan, Teotihuacan, Mexico, during June 18-22, 1995. The presentations at the workshop provided a state of the art review of the fundamental aspects of the CVM and PPM and their application to a wide range of problems in statistical mechanics and alloy theory. The volume begins with several articles dealing with the study of the kinetics of ordering in Ising sytems and alloys using the PPM and other classical techniques. These articles are followed by the contribution of Professor Masuo Suzuki on the Coherent Anomaly Method which has added a new dimension to mean field theory, and the CVM in particular, in the study of critical phenomena. The remaining of the volume is dedicated to fundamental aspects and specific applications of the CVM in a wide range of subjects ranging from bulk and surface studies to new areas of inquiry such as the problem of image reconstruction. Since the inception by Prof. Ryoichi Kikuchi of the CVM in 1950 and of the PPM in 1966, the latter after a gestation period of approximately six years, the tech niques have found wide acceptance in the physics and materials science communities. Both methods are properly regarded as seminal contributions to equilibrium and non equilibrium statistical mechanics. 440 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The science ofparasitology is particularlyrelevantto the health ofhumans and animals throughout the world. As such, it provides the core of the Rockefeller Foundation program ofbiomedical research called The Great Neglected Diseases of Mankind. While some bacterial, viral, and fungal diseases are included in this program, the parasiticdiseases caused bypro tozoa and helminths almost uniformly fit into this category. Many ofthem infect vast numbers of people and animals (of the order of hundreds of millions), but theyare greatlyneglected bythe scientific establishmentof the modern world. The principal reason for this neglect, both scientific and financial, is the fact that these diseases are primarily problems ofthe developing world. Hence, no vaccines exist for anyofthe human parasitic diseases; for many, treatment is either nonexistent or highly toxic; and diagnosis still relies largely on the visual examination ofbiopsies, blood, and excreta. In contrast, the discovery ofa spate ofantibiotics has revolu tionized treatment of bacterial diseases, and vaccines have been devel opedfor manybacterial andviral diseases. Furthermore, the field ofmicro biology, which deals largely with bacteriology and virology, has sparked the scientific revolutions ofimmunology and molecular biology. In order to examine the present status of parasitology and the reasons for its putative neglect, as well as to develop means of remedying the sit uation, aseries ofconferences has been convened, bringing together clas sical parasitologists and a new and complementary breed of parasite-ori ented immunologists, biochemists, molecular biologists, and population ecologists. 308 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The field of reactive intermediates has been blossoming at a rapid rate in recent years and its impact on chemistry, both 'pure' and 'applied,' as well as on biology, astronomy, and other areas of science, is enormous. Several books have been published which cover the area; one, edited by McManus, \* surveys the subject in general at the senior undergraduate or beginning graduate level. In addition, a number of monographs have appeared which deal with individual topics such as carbenes, nitrenes, free radicals, carbanions, carbenium ions, and so on, in great depth. Our objective is somewhat different. We hope that these Advances in . . . type of volumes will appear at irregular intervals of a year to 18 months each. We intend to publish up-to-date reviews in relatively new areas of the chemistry of reactive intermediates. These will be written by world authorities in the field, each one of whom will give the reader a current in-depth review of all aspects of the chemistry of each of these species. It is our plan that the subjects to be reviewed will cover not only organic chemistry but also inorganic, physical, bio-, industrial, and atmospheric chemistry. The volumes themselves, we hope, will end up being reasonably interdisciplinary, though this need not and probably will not be the case for the individual reviews. 616 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over the last several decades, the remarkable success of science and medical technology has allowed many children with chronic illness and handicapping conditions to live longer and healthier lives. But this suc cess is not without toll. The human cost of chronic illness or a handicap ping condition can be enormous for the child and the family. For the family, there is often the stressful daily burden of care, fatigue, marital stress, low family morale, financial burdens, and reduced career mobili ty. For the child, there are often arduous and painful treatment regimes, frequent school absences, low energy periods, and uncertainties with respect to future education and vocation. The course of many diseases is unpredictable, and the very fact of chronicity implies ongoing coping problems for the family and the child. The impact of a chronic illness or handicapping condition on a family system is usually more disintegrative than integrative, disrupting the lives of all family members and exacerbating the developmental risks to the child. It is not surprising that a recent comprehensive study for establish ing public policies for children with chronic illness at Vanderbilt Univer sity has called attention to these factors and produced, as a primary recommendation, increased attention to the psychological impact of dis ease on the family and the child. In this context there is an important need for adequate assessment of psychological and behavioral problems in these children to plan for appropriate services. 388 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Psychology of the Dentist-Patient Relationship acquaints dentists with the underlying interpersonal dynamics of their professional work. The author has reviewed the dental and psychological literature about the behavior of dentists and their patients, and used this evidence to evaluate critically the various theoretical models of the dentist-patient relationship. A major aim of this book is to show how the application of soundly based psychological theory and practice can improve patient management, reduce the stress of practicing dentistry, and contribute to the design of effective community dental health campaigns. 200 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -vitro methodology for the cultivation of erythroid The purpose of In Vitro Aspects of Erythropoiesis is to broaden our understanding of the regulation of stem cells. The second series of papers treats cellular normal and neoplastic hematopoietic cells by means and soluble factors which affect erythroid stem cell of a synthesis of different techniques, divergent no differentiation. Hormonal modulation of in vitro menclature as well as a closer standardization of re erythropoiesis is the theme of the third session fol agents and methods which had heretofore produced lowed by a series of papers in the fourth which fo vagaries of results among different laboratories. cuses on erythropoiesis after transformation by ei Hence the papers, discussions and appendices pre ther Friend or Rauscher viruses. The fifth session deals with serum inhibitors to erythropoiesis and the sented in this volume will be of value and interest to investigators and clinicians as well as to students and role of the macrophage in red blood cell production. teachers of hematology. Finally, the sixth session concentrates on the biogen In Vitro Aspects of Erythropoiesis is comprised of esis of erythropoietin in vivo and in vitro. thirty papers delivered by twenty invited contribu Each of the six sections is followed by a discus tors at a three day conference which was held in sion which was transcribed and initially edited at the Capri, Italy in October of 1977. The contributors meeting. 304 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is a study of how a bureaucracy allocates a commodity or a service in this case, public housing. In the broadest sense, it seeks to understand how bureaucrats try to resolve two often conflicting goals of regulatory justice: equity (treating like cases alike on the basis of rules) and respon siveness (making exceptions for persons whose needs require that rules be stretched). It analyzes the extent to which such factors as bureaucratic norms, the task orientation of workers, third-party pressure, and outside intervention affect staff members' use of discretion. Many of the rules under consideration were intended by federal officials to achieve such programmatic objectives as racial desegregation and housing for the neediest; in this regard, the study is also an examination of federal-local relationships. Finally, the study examines how the use of discretion changes over time as an agency's mission shifts and reforms are attempted. This book is directed at the audience of administrators of programs who offer services to the public and struggle with how to allocate them. The book is also intended for those concerned with housing policy, partic ularly the difficult problems of whom to house. Finally, it is hoped that students of public management, social welfare, government, and urban planning, who are interested in how public policy is administered through a bureaucracy, will find the book insightful. The case chosen for study is the Boston Housing Authority. 244 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the two decades before the mid-1970s, macroeconomic policies in Western Europe were frequently accompanied by policies of direct wage restraint in the pursuit of acceptable levels of employment, inflation, and international competitiveness. The same period witnessed a proliferation of social welfare programs, elements of which were sometimes commingled with demand management and pay policies in trilateral bargaining processes involving gov ernments, unions, and employers. In the wake of such subsequent develop ments as the oil price shocks, sharply intensified international competition, and slowing of growth rates in productivity, however, governments resorted more frequently to deflationist macroeconomic policies and also to policies aimed directly at increasing IIflexibility' in wage determination and the de ployment of labor by the firm. It is a major theme of this very interesting book that these labor market policies have not been demonstrably (or at least sufficiently) effective in com bating the high rates of unemployment which have been prevalent in most of the countries of Western Europe since the late 1970s. This theme emerges from the chapters on labor market developments and policies in six countries of Western Europe, the United States, and Hungary (a welcome addition to this type of scholarship), as well as another set of chapters'devoted to specific policy areas. In effect, Samuel Rosenberg and his colleagues-an interna tional team of nineteen economists and sociologists-are repeating in con crete terms a sermon preached by Keynes over a half century ago. 280 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Somehow it surprises me that this book wasn't written earlier, but I'm glad it wasn't. If it had been, Frank Koch probably wouldn't have sensed the vacuum that has existed, and this practical book wouldn't have come to be. I'd like to stress practical. The book describes in a comprehensive and-more importantly-practical way how every corporation can mar shal its financial support, employee talents, and other resources to make a meaningful impact on society. I happen to be one of those corporate executives who believes that a business has a responsibility to make such an impact. My brother Peter agrees. Our father and uncle set an example for us, and the tradition goes back to our great uncles and their uncle, Levi Strauss himself. For more than 125 years Levi Strauss & Co. has shown that social responsibil ity is good business and, in recent years, that it is also compatible with dynamic growth. We are proud of that tradition and what it produced, but 1 think the modern era of social responsibility or corporate citizenship at Levi's got its impetus in 1968 with my association with the National Alliance of Businessmen. It was there that I saw what other companies were doing: innovative ways to train, to transport, to provide jobs. It opened my eyes to areas in which business could become involved, areas I never before thought of as business responsibilities-even areas where it could have an impact. 316 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This report originated in a request to me from the Board of Trustees of the Ford Foundation in the summer of 1975. The trustees, aware that there would be a change of leadership at the Foundation be fore 1980, wanted to make a running start in the process of plan ning for the future. Their first step was to make a study of the great national and international needs that might lie ahead in the next decade and a half, and where and how the Foundation might ad dress them. They sought advice both within the Foundation and outside it, and they engaged in long discussions of their own. Although the exercise was directed toward planning for the future, the trustees also wished to review our past, not exhaus tively but at least well enough to have a clear sense of what the Foundation had been up to in the quarter century of its existence as a national and international institution. In this connection, the chairman of our board, Alexander Heard, asked for /I a canvass of the Ford Foundation's experiences, successes, and failures during the last twenty-five years . . . [focused] on the broad objectives sought, the means pursued to achieve them, and the results. 228 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Intercellular communication in multicellular organisms enables cells to respond to environmental changes. Intercellular signal transduction transmitters include hormones, peptide growth factors, neurotransmitters as well as some lipid-soluble mediators. Once signalling molecules are bound to their cell surface receptors, one or more intracellular signals are generated which alter the Qehavior of the target cell. The IXth International Washington Spring Symposium at the George Washington University in Washington, D.C. was organized to assess the current status of the field of signal transduction processes and regulatory mechanisms. The symposium was held on May 8-'.2, 1989 and was attended by more than 1000 scientists from 30 countries. Most of the papers presented at the plenary sessions have been collected in this volume. The first section of this book details the action and regulation of receptors such as ,B-pdr.'nergic receptors and receptors for EGF, insulin, leukotrienes, phosphoinositides and prostaglandins. Section two focuses on the family of guanine nucleotide regulatory proteins (G proteins). These G proteins are known to mediate the coupling of receptor-mediated signals to several intracellular effector systems. Papers are presented describing the intracellular localization of G proteins, the utilization of G protein antibodies, the interaction of G proteins with tubulin and the involvement of G proteins in the regulation of ion channels, adenylate cy~lase and in the activation of neutrophils and T cells. In the third section, several papers describe the second messenger role of phosphoinositides as well as the regulation of phosphoinositide production. 432 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is generally accepted that. fused BZ03 is composed of B0 3 triangles. These triangles are joined togetner randomly, forming l the glass network. I.R. studies and x-ray diffraction studies on pure BZ03 glass indicated clearly that these triangles are joined together forming boroxole groups. These groups are joined together forming the random network. It is also accepted that addition of alkali oxides to boron oxide results in a glassy network in 468 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume represents the findings of the six-year NATO CCMS pilot study on the use of remote sensing for the control of marine pollution, a joint study conducted by countries confronted by the problems that arise from the prevention of, and the fight against, deliberate and accidental oil spills. In 1976, when I submitted to the Committee on the Challenges of Modern Society the draft of this pilot study, the use of remote sensing in the area covered by the project was still at the experimental research stage. Two years later, the Amoco Cadiz disaster occurring on the Brittany Coast gave ~he opportunity to demonstrate the important role that remote sensing could play in the fight against major oil spills. At the same time, many countries engaged in the fight against the deliberate discharge of oil from ships became aware of the po tential of remote sensing to help combat this type of illegal activity. Compiling this volume has afforded me the opportunity to re-read the papers that were presented at the workshops in Washington, D.C. and Paris, which were held April 1979 and October 1982, respectively. Not only is the material still of current interest, but also some recommendations expressed by the experts have already received international recognition. This applies, in particular, to the Isowake experiments, which were originated by the United States (U.S. Coast Guard) and the United Kingdom (Warren Spring Laboratory). 484 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thermoelectric and related transport properties of metals have been a source of information and, also, exasperation to physicists for over a century. Perhaps the principal reasons for interest in these phenomena are their sensitivity to composition, structure and external fields and, until fairly recently, the distressing fact that often even gross experimental features such as the sign of the thermopower eluded theoretical understanding. During the past two decades many of the previously perplexing aspects of thermoelectricity have yielded to more sophisticated theoretical treat ment. As a result of this effort and concomitant experimental work using advanced measurement techniques, there is now good reason to believe that thermoelectric phenomena can shed much light on the interactions between electrons and phonons, impurities, and other defects. The last few years have witnessed new and fascinating developments that promise to stimulate new activity in this field. In contrast to the more conventional transport properties, second-and high-order contributions in electron scattering theory appear to play a profound role in thermoelectricity-the controversy surrounding ordinary and 'phony' phonon drag is far from resolved; the startlingly large effect of magnetic fields on the thermopower of metals appears to be linked intimately to scattering anisotropy; quantum oscillations of thermopower are orders of magnitude larger than corresponding oscillations of the magnetoresistance; a new approach to thermoelectric studies allows extension of thermopower measurements into the millikelvin region of temperature; finally, the advent of superconducting detection devices permits the precise measurement of extremely small voltages, an essential requirement in this field. 284 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents plenary lectures and invited papers that Were delivered during the Fourth Australian Conference on Electro chemistry held at The Flinders University of South Australia, 16-20th February 1976. EZeat~oahemi8try fo~ a Futu~e Soaiety was selected as the Conference theme since the organising committee were mindful of the rapid change in technological perspective which the world now faces. We no longer have a prospect of uncontrolled spontaneous expansion and change as the result of technological enterprise. Rather, we face the task of attempting to reach a state of very restricted growth. In the next few decades special accent must be placed on minimizing pollution and maximizing the efficient utilization of all available energy sources. With this in mind, the Conference organisers considered that a conventional electrochemistry symposium, with its divisions into the various academic aspects, would be less relevant than a meeting devoted to aspects of electrochemistry which may underlie parts of the new and necessary technology for the future state of affairs. What has actually been achieved by the Conference organisers is a balance between the ideals expressed and the resulting response from electrochemists. This response has a bias which reflects the dominance of certain resources, e.g. metallic minerals, within Australia. Consequently, the papers included in T~ends in EZeat~o ahemist~ cover subjects which are of both global and local concern. 424 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -At the present time there are renewed global efforts to control the major tropical infections and to stem the tide of malnutrition, the two serious, often intertwined, problems that contribute to much of the morbidity and mortality in under privileged populations. Many international organizations have joined hands with national governments and with the private sector to search for new approaches to problems that beset much of the developing world, including countries in the tropical region. This volume continues the tradition of the previous publication in the Series. A variety of fare is offered to readers: explanations of the activities and achievements of the UNDP/World Bank/WHO Special Programme for Re search and Training in Tropical Diseases; and studies of infant mortality, schistosomiasis, trypanosomiasis, helminths, lactase deficiency, oral rehydration therapy, functional consequences of iron deficiency, and fertility control. Au thoritative state-of-the-art reviews provide a critical analysis of recent data. I hope the Series will continue to prove useful to all those working in the tropics and to those in the industrialized countries whose awareness of physical health problems of the Third World is relatively limited. R. K. Chandra St. John's, Newfoundland VlI Contents Chapter 1. The Special Programme for Research and Training in Tropical Diseases . . . . . . . . . . . . . . . . . . . DAVID S. ROWE 1. Origins, Objectives, and Diseases. . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. The Modus Operandi of the Programme. . . . . . . . . . . . . . . . . . . . . . 3 2. 1. Scientific Working Groups. . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. 2. Research Strengthening Group. . . . . . . . . . . . . . . . . . . . . . . . . 7 2. 3. TheScientific and Technical Advisory Committee. . . . . . . . . 7 2. 4. Joint Coordinating Board. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292 pp. Englisch.