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Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493901281ISBN 13: 9781493901289
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For over three decades, this best-selling classic has been used by thousands of students in the United States and abroad as a must-have textbook for a transitional course from calculus to analysis. It has proven to be very useful for mathematics majors who have no previous experience with rigorous proofs. Its friendly style unlocks the mystery of writing proofs, while carefully examining the theoretical basis for calculus. Proofs are given in full, and the large number of well-chosen examples and exercises range from routine to challenging.The second edition preserves the book's clear and concise style, illuminating discussions, and simple, well-motivated proofs. New topics include material on the irrationality of pi, the Baire category theorem, Newton's method and the secant method, and continuous nowhere-differentiable functions. 424 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493925458ISBN 13: 9781493925452
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In creating interpretive strategies for maritime sites, archaeologists and resource managers often are required to think creatively to overcome challenges and problems. These issues include interpreting sites in inaccessible locations and extremely deep water, enabling and controlling access to fragile sites and restricted areas, monitoring visitor behavior, making information interesting to a wide audience, and creating opportunities for public engagement, among other concerns. Meeting Challenges presents cutting-edge interpretation and public education strategies for maritime resources, both on land and underwater, with emphasis on solving the unique problems often associated with presenting these fragile, limited-access sites as heritage attractions and on developing effective visitation and civic engagement opportunities. The examples presented ideally can serve as models for resource managers, archaeologists engaged in interpretation, and site administrators. This volume brings together a diverse group of heritage professionals to discuss issues they've encountered and to present ideas and case studies for adapting, improvising, and overcoming them. 228 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493923730ISBN 13: 9781493923731
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is the most up-to-date text available on diffuse malignant mesothelioma and includes all the newest imaging modalities, immunohistochemical features, and ever-expanding information on the molecular characteristics of the cancer. In-depth chapters contain fully referenced text as well as detailed tables and images. While the primary audiences for this book are pathologists and pathology residents, the broad examination of diffuse malignant mesothelioma, including its epidemiology, makes this book valuable to radiologists, surgeons, oncologists, and other clinical physicians and their residents as well.Written by experts in the field, Diffuse Malignant Mesothelioma is a concise yet comprehensive resource for clinicians involved in the management of one of the most widely recognized and feared cancers in the world. 156 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493901990ISBN 13: 9781493901999
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The goal of this book is to show how to build and manage a food safety department that is tasked with ensuring food safety within a food retail business. The experiences of the author as the head of Food and Product Safety at Chick-fil-A will be used as the model. Specifically, the book will discuss the specific components of a food safety program, the tactics needed to establish these components (forming the majority of the chapters), how to measure the success of each component, and how to influence the organization to ensure resources to support the program. The book will also focus on how to choose and work with the appropriate partners, validate the value to the business, and initiate the new component throughout the organization, including how to sustain the component within the program. Five features of this book that make it distinctive are: Most current 'How to' book on leading a food safety department from the perspective of a respected national brandProvides the proper organization and methods to manage the work necessary to ensure food safety within the organization Provides the means to utilize risk-based decisions linked to business practices that accommodate a business analysis model Demonstrates step-by-step examples that can be used for continuous improvement in sustaining food safety responsibilities Provides examples on how to gain influence and obtain resources to support food safety responsibilities 144 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489998942ISBN 13: 9781489998941
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since 1978, the opening up and reform in China has brought tremendous economic and social changes. While China's economic progress has been commendable, the social problems that go with economic changes have raised serious concerns. Some of those concerns are related to gender, ethnic, labor, and environmental issues. This book is about what has happened in these arenas in China since the opening up and reform in 1978. The study of gender, ethnicity, labor, and environment touches on some of the fundamental problems of modernization, especially the development of individuals and groups. So even though gender, ethnicity, labor, and environment seem to be separate issues, they are in fact related in some fundamental ways. That's what this book will explore as well. To understand is one thing and to do is another. This book also incorporates studies of NGO practices to see how NGOs have helped in transforming gender, ethnic, labor, and environment interplay. Our study of NGOs in helping improve such interplay sheds light on how specifically civil society can prod the state to transform social relations for the better. This book is an attempt to assess the changes, both positive and negative, in gender, ethnic, ethnic, and environmental relations in China especially in the past 30 years of opening up and reform, especially regarding national identity formation. 344 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489998136ISBN 13: 9781489998132
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is designed as an introductory course in Tropical Meteorology for the graduate or advanced level undergraduate student. The material within can be covered in a one-semester course program. The text starts from the global scale-view of the Tropics, addressing the zonally symmetric and asymmetric features of the tropical circulation. It then goes on to progressively smaller spatial and time scales - from the El Niño Southern Oscillation and the Asian Monsoon, down to tropical waves, hurricanes, sea breezes, and tropical squall lines. The emphasis in most chapters is on the observational aspects of the phenomenon in question, the theories regarding its nature and maintenance, and the approaches to its numerical modeling. The concept of scale interactions is also presented as a way of gaining insight into the generation and redistribution of energy for the maintenance of oscillations of a variety of spatial and temporal scales. 440 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 148998710XISBN 13: 9781489987105
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Signals and Transforms in Linear Systems Analysis covers the subject of signals and transforms, particularly in the context of linear systems theory. Chapter 2 provides the theoretical background for the remainder of the text. Chapter 3 treats Fourier series and integrals. Particular attention is paid to convergence properties at step discontinuities. This includes the Gibbs phenomenon and its amelioration via the Fejer summation techniques. Special topics include modulation and analytic signal representation, Fourier transforms and analytic function theory, time-frequency analysis and frequency dispersion. Fundamentals of linear system theory for LTI analogue systems, with a brief account of time-varying systems, are covered in Chapter 4 . Discrete systems are covered in Chapters 6 and 7. The Laplace transform treatment in Chapter 5 relies heavily on analytic function theory as does Chapter 8 on Z -transforms. The necessary background on complex variables is provided in Appendix A. This book is intended to serve as a text on signals and transforms for a first year one semester graduate course, primarily for electrical engineers. 392 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493915584ISBN 13: 9781493915583
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a theoretical background of branching processes and discusses their biological applications. Branching processes are a well-developed and powerful set of tools in the field of applied probability. The range of applications considered includes molecular biology, cellular biology, human evolution and medicine. The branching processes discussed include Galton-Watson, Markov, Bellman-Harris, Multitype, and General Processes. As an aid to understanding specific examples, two introductory chapters, and two glossaries are included that provide background material in mathematics and in biology. The book will be of interest to scientists who work in quantitative modeling of biological systems, particularly probabilists, mathematical biologists, biostatisticians, cell biologists, molecular biologists, and bioinformaticians. The authors are a mathematician and cell biologist who have collaborated for more than a decade in the field of branching processes in biology for this new edition.This second expanded edition adds new material published during the last decade, with nearly 200 new references. More material has been added on infinitely-dimensional multitype processes, including the infinitely-dimensional linear-fractional case. Hypergeometric function treatment of the special case of the Griffiths-Pakes infinite allele branching process has also been added. There are additional applications of recent molecular processes and connections with systems biology are explored, and a new chapter on genealogies of branching processes and their applications.Reviews of First Edition:'This is a significant book on applications of branching processes in biology, and it is highly recommended for those readers who are interested in the application and development of stochastic models, particularly those with interests in cellular and molecular biology.' (Siam Review, Vol. 45 (2), 2003)'This book will be very interesting and useful for mathematicians, statisticians and biologists as well, and especially for researchers developing mathematical methods in biology, medicine and other natural sciences.' (Short Book Reviews of the ISI, Vol. 23 (2), 2003) 300 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489996907ISBN 13: 9781489996909
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book was written to provide resource materials for teachers to use in their introductory or intermediate statistics class. The chapter content is ordered along the lines of many popular statistics books so it should be easy to supplement the content and exercises with class lecture materials.The book contains R script programs to demonstrate important topics and concepts covered in a statistics course, including probability, random sampling, population distribution types, role of the Central Limit Theorem, creation of sampling distributions for statistics, and more. The chapters contain T/F quizzes to test basic knowledge of the topics covered. In addition, the book chapters contain numerous exercises with answers or solutions to the exercises provided. The chapter exercises reinforce an understanding of the statistical concepts presented in the chapters. An instructor can select any of the supplemental materials to enhance lectures and/or provide additional coverage of concepts and topics in their statistics book. 308 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493921339ISBN 13: 9781493921331
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since the publication of the first edition,Biostatistics and Epidemiologyhas attracted loyal readers from across specialty areas in the biomedical community. Not only does this textbook teach foundations of epidemiological design and statistical methods, but it also includes topics applicable to new areas of research. Areas covered in the fourth edition include a new chapter on risk prediction, risk reclassification and evaluation of biomarkers, new material on propensity analyses, and a vastly expanded chapter on genetic epidemiology, which is particularly relevant to those who wish to understand the epidemiological and statistical aspectsof scientific articles in this rapidly advancing field. Biostatistics and Epidemiologywas written to be accessible for readers without backgrounds in mathematics. It provides clear explanations of underlying principles, as well as practical guidelines of 'how to do it' and 'how to interpret it.' Key features include a philosophical and logical explanation at the beginning of the book, subsections that can stand alone or serve as reference, cross-referencing, recommended reading, and appendices covering sample calculations for various statistics in the text. 280 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489990305ISBN 13: 9781489990303
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Statistical Methods for Dynamic Treatment Regimes shares state of the art of statistical methods developed to address questions of estimation and inference for dynamic treatment regimes, a branch of personalized medicine. This volume demonstrates these methods with their conceptual underpinnings and illustration through analysis of real and simulated data. These methods are immediately applicable to the practice of personalized medicine, which is a medical paradigm that emphasizes the systematic use of individual patient information to optimize patient health care. This is the first single source to provide an overview of methodology and results gathered from journals, proceedings, and technical reports with the goal of orienting researchers to the field. The first chapter establishes context for the statistical reader in the landscape of personalized medicine. Readers need only have familiarity with elementary calculus, linear algebra, and basic large-sample theory to use this text. Throughout the text, authors direct readers to available code or packages in different statistical languages to facilitate implementation. In cases where code does not already exist, the authors provide analytic approaches in sufficient detail that any researcher with knowledge of statistical programming could implement the methods from scratch. This will be an important volume for a wide range of researchers, including statisticians, epidemiologists, medical researchers, and machine learning researchers interested in medical applications. Advanced graduate students in statistics and biostatistics will also find material in Statistical Methods for Dynamic Treatment Regimes to be a critical part of their studies. 220 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489986936ISBN 13: 9781489986931
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -New data have come to light through the Solution Focused Brief Therapy Association Archive (hereafter, the Archive). This information is drawn from manuscripts and video featuring one of the SF founders, Insoo Kim Berg, MSW. Archive video examples of Ms. Berg conductingsupervision, therapy teams, and case consultation as well as unpublishedmanuscripts written by her provide unique opportunities to illustrate specific assumptions and techniques rarely seen before. The documents outline Ms. Berg's philosophy, assumptions, and techniquesto conduct supervision, and the videos offer in vivo examples of her supervision and team/case consultation style. Together, the Archive materials offer a rich resource for a book that both informs and illustrates SFS . 376 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493924370ISBN 13: 9781493924370
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume aims to describe a variety of techniques that reflects the wide range of research currently performed in the field of coronavirology, and begins with an overview of current understandings of coronavirus replication and pathogenesis to introduce specialists and non-specialists to the field. The rest of the book is divided into several sections of chapters beginning with those that describe identification, diagnosis, and study of the evolution of coronaviruses. The next few chapters discuss the preparation of cells and organ cultures useful in propagating coronaviruses and titration techniques, as well as techniques for analyzing virus functions that require purification of the viruses. The next chapters describe two commonly used reverse genetics techniques for coronaviruses, and techniques detailing identification of cellular receptors, binding profiles of viral attachment proteins, and virus-cell fusion. The final chapters cover a broad spectrum of techniques to identify virus-host protein-protein interactions, confirm the functional role of these proteins in virus replication, study host cell responses through genome-wide or pathway-specific approaches, and visualize virus replication complexes. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.Authoritative and practical, Coronaviruses: Methods and Protocols appeals to a wide variety of scientists because it highlights techniques that are currently used in the coronovirology field, while also discussing practices applicable to other virology fields. 300 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489990925ISBN 13: 9781489990921
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book contains a detailed account of the result of the author's recent Annals paper and JAMS paper on arithmetic invariant, including mi-invariant, L-invariant, and similar topics. This book can be regarded as an introductory text to the author's previous book p-Adic Automorphic Forms on Shimura Varieties. Written as a down-to-earth introduction to Shimura varieties, this text includes many examples and applications of the theory that provide motivation for the reader. Since it is limited to modular curves and the corresponding Shimura varieties, this book is not only a great resource for experts in the field, but it is also accessible to advanced graduate students studying number theory. Key topics include non-triviality of arithmetic invariants and special values of L-functions; elliptic curves over complex and p-adic fields; Hecke algebras; scheme theory; elliptic and modular curves over rings; and Shimura curves. 468 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493920340ISBN 13: 9781493920341
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume reviews the evolution of information regarding the epidemiology of DCIS and its modes of detection, as well as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing 'true' DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer.Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer. 184 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493924346ISBN 13: 9781493924349
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume collects a series of protocols describing the kinds of infrastructures, training, and standard operating procedures currently available to actualize the potential of stem cells for regenerative therapies. Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations pulls together key GMP techniques from laboratories around the world. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Inclusive and authoritative, Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations will be an invaluable resource to both basic and clinical practitioners in stem cell biology. 232 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493920316ISBN 13: 9781493920310
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This comprehensive treatise on cutting edge tools and research provides a fascinating insight into the rapidly evolving field of diagnostic and therapeutic endoscopy. Accomplished international researchers and clinicians discuss the latest endoscopic advances in diverse areas including obesity and associated metabolic syndromes, management of peripancreatic fluid collections, endoluminal suturing techniques, fistula closure, management of Barrett's epithelium, cholangioscopy, chromoendoscopy, high resolution manometry and endoscopic ultrasonography. Gastrointestinal Endoscopy: New Technologies and Changing Paradigms is a valuable resource on the evolving role of endoscopic management of gastrointestinal diseases and is a tremendous resource for gastroenterologists, endoscopists, GI surgeons, and medical residents. 232 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493921622ISBN 13: 9781493921621
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a comprehensive overview of key technologies being used to address challenges raised by continued device scaling and the extending gap between memory and central processing unit performance. Authors discuss in detail what are known commonly as 'More than Moore' (MtM), technologies, which add value to devices by incorporating functionalities that do not necessarily scale according to 'Moore's Law'. Coverage focuses on three key technologies needed for efficient power management and cost per performance: novel memories, 3D integration and photonic on-chip interconnect. 228 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493923129ISBN 13: 9781493923120
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents a collection of protocols for immunocytochemical analysis of neurons and neural networks. Chapters focus on immunocytochemical localization at light and electronic levels, biochemical characterization, and functional analysis in vivo or ex vivo by novel types of microscopy, as well as protocols for development and production of genetic probes. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.Essential and authoritative, Immunocytochemistry and Related Techniques is intended for a large audience of scientists, including histologists, biochemists, cellular and molecular biologists, electrophysiologists that are currently active in the field or are willing to enter the exciting area of neuroscience research. 488 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493923056ISBN 13: 9781493923052
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume aims to explore the latest developments in adeno-associated viral and lentiviral vectors as well as the gene therapy strategies for the most common neurological disorders, followed by chapters that include step-by-step guides to viral vector-based gene delivery in animal models used in the authors' laboratories. Although safe gene manipulation in neural cells can be achieved, it may still be years away from efficacious gene-based treatment of neurological disorders such as Parkinson's and Alzheimer's diseases due to the complexity of the underlying genetic/molecular mechanisms and the difficulty of developing reliable animal models. Gene Delivery and Therapy for Neurological Disorders seeks to aid researchers in this vital work. Written in the popular Neuromethods series format, chapters include the kind of detailed description and expert implementation advice that leads to success in the lab.Meticulous and authoritative, Gene Delivery and Therapy for Neurological Disorders serves as an ideal guide for researchers attempting to explore the potentials of gene therapy for neurological disorders. 376 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493922165ISBN 13: 9781493922161
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a state-of-the-art review of the role of radiation therapy in various pelvic malignancies as well as the consequences of the radiation in the pelvic tissues. With sections covering the role of radiation therapy in the various pelvic malignancies, the pathophysiology of radiation related injury and the risk factors that increase the possibility of such an injury, and the latest in medical, endoscopic and surgical therapies for these radiation related complications the text offers a concise yet comprehensive overview of radiation therapy in the human pelvis, its role and the adverse effects on the pelvic organs. Written by experts in the field with readers in mind, Radiation Therapy for Pelvic Malignancy and its Consequences is the first of its kind standalone reference on the subject. Radiation Therapy for Pelvic Malignancy and its Consequences is of great value to urologists, medical radiation and gynecological oncologists, and gastroenterologists. 244 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493923528ISBN 13: 9781493923526
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this volume expert researchers in the field detail the operations of microchip capillary electrophoresis. Chapters focus on small molecule, biomolecule applications, various detection modes, and sample preparation approaches are described. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Microchip Capillary Electrophoresis Protocol aids scientists in continuing to study microchip capillary electrophoresis. 212 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493923919ISBN 13: 9781493923915
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is designed to be a resource of proven techniques and approaches for probing the activities of bacterial, eukaryotic, and archaeal RNA polymerases. This book features a collection of in vitro and in vivo technologies that will permit researchers to purify and probe the position and stability of RNA polymerase complexes at different points of the transcription cycle, analyze the various translocations and intermolecular movements associated with catalysis, define recruitment strategies, probe the roles of transcription factors in each stage of the cycle, highlight conserved and disparate fidelity mechanisms, analyze the resultant transcripts, and study coordination of the nascent mRNA synthesis by the RNA polymerase and mRNA translation by the ribosome. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubles troubleshooting and avoiding known pitfalls. Practical and timely, Bacterial Transcriptional Controls: Methods and Protocols highlights the breadth and depth of techniques that are likely to continue shaping the transcription community in the future. 356 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493923765ISBN 13: 9781493923762
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). Chapters focus on technologies and chemometrics, generation of metabonomics data, extraction of meaningful information from data, drug development, toxicology, diagnostics, and describing metabonomics as an essential part of systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 272 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493900641ISBN 13: 9781493900640
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book develops voltage-to-frequency converter (VFC) solutions integrated in standard CMOS technology to be used as a part of a microcontroller-based, multisensor interface in the environment of portable applications, particularly within a WSN node. Coverage includes the total design flow of monolithic VFCs, according to the target application, as well as the analysis, design and implementation of the main VFC blocks, revealing the main challenges and solutions encountered during the design of such high performance cells. Four complete VFCs, each temperature compensated, are fully designed and evaluated: a programmable VFC that includes an offset frequency and a sleep/mode enable terminal; a low power rail-to-rail VFC; and two rail-to-rail differential VFCs. 160 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493923293ISBN 13: 9781493923298
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume explores the technological improvements in protein engineering, expression, purification, and crystallization of several rhodopsin photoactive intermediates, thus increasing our understanding of rhodopsin activation. The first chapters of the book focus on methods developed to study fundamentals of rhodopsin structure and function, starting with improved purification protocols of native and mutated rhodopsin, followed by methods used for rhodopsin reconstitution into lipid bilayers stabilizing rhodopsin function properties, and finally describing recently developed methods to study structural dynamics of rhodopsin activation and its mechanistic properties. Subsequently, chapters underline various techniques that have been developed to visualize the rhodopsin dimer and to study its functional significance. The next few chapters highlight cutting-edge imaging techniques of photoreceptors, rhodopsin trafficking, and its diffusion within signaling membranes. Finally the book concludes with recent developments that could be potentially beneficial in patient treatments, and treatment strategies for retinal degenerative diseases. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.Timely and practical, Rhodopsin: Methods and Protocols reaches out to researchers and health practitioners, and provides timely protocol useful for studying structural and functional properties of rhodopsin. 428 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489990852ISBN 13: 9781489990853
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This thesis represents the first wide-field photometric and spectroscopic survey of star clusters in the nearby late-spiral galaxy M33. This system is the nearest example of a dwarf spiral galaxy, which may have a unique role in the process of galaxy formation and evolution. The cold dark matter paradigm of galaxy formation envisions large spiral galaxies, such as the Milky Way, being formed from the merger and accretion of many smaller dwarf galaxies. The role that dwarf spiral galaxies play in this process is largely unclear. One of the goals of this thesis is to use the star cluster population of M33 to study its formation and evolution from its early stages to the present. The thesis presents a new comprehensive catalog of M33 star clusters, which includes magnitudes, colors, structural parameters, and several preliminary velocity measurements. Based on an analysis of these data, the thesis concludes that, among other things, the evolution of M33 has likely been influenced by its nearby massive neighbor M31. 148 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489995722ISBN 13: 9781489995728
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Why has the clean, limitless energy promised by fusion always seemed just out of reach Search for the Ultimate Energy Source: A History of the U.S. Fusion Energy Program, explains the fundamentals and concepts behind fusion power, and traces the development of fusion historically by decade-covering its history as dictated by US government policies, its major successes, and its prognosis for the future. The reader will gain an understanding of how the development of fusion has been shaped by changing government priorities as well as other hurdles currently facing realization of fusion power. Advance Praise for Search for the Ultimate Energy Source:'Dr. Dean has been uniquely involved in world fusion research for decades and, in this book, describes the complicated realities like few others possibly could.'-Robert L. Hirsch, a former director of the US fusion program, an Assistant Administrator of the US Energy Research and Development Administration (ERDA); an executive at Exxon, Arco, and the Electric Power Research Institute (EPRI); and lead author of the book The Impending World Energy Mess (Apogee Prime Books, 2009).'In this book, Dr. Dean provides the many reasons why fusion has progressed more slowly than many had hoped. Budget is usually cited as the culprit, but policy is equally to blame. Facilities have been closed down before their jobs were done-or in some cases, even started. It seems this situation has become endemic in fusion, and if one thinks about it, in other nationally important Science and Technology initiatives as well.'-William R. Ellis, a former scientist at Los Alamos National Laboratory, Associate Director of Research at the US Naval Research Laboratory, a vice president at Ebasco Services and at Raytheon, and chair of the US ITER Industry Council and the US ITER Industrial Consortium. 280 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1493924850ISBN 13: 9781493924851
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume covers the techniques necessary for a successful fragment-based drug design project, beginning from defining the problem in terms of preparing the protein model, identifying potential binding sites, and the consideration of various candidate fragments for simulation. The second part discusses the technical aspects that various methods have used to simulate fragment binding to a target protein by using Monte Carlo, molecular dynamics, and docking algorithms. After simulations, fragments are assembled into molecules using a variety of approaches, which are explored next. A discussion of design strategies and consideration of drug-like properties is included as part of the design process at this stage. Finally, several examples of successful fragment-based drug design projects are presented. Written for the Methods in Molecular Biology series, this work contains the kind of detailed description and implementation advice to encourage success in the lab.Practical and cutting-edge, Fragment-Based Methods in Drug Discovery takes into account the great accomplishments in the field to provide an ideal guide for researchers continuing to investigate this exciting area of pharmacological study. 240 pp. Englisch.
Verlag: Springer New York Feb 2015, 2015
ISBN 10: 1489996192ISBN 13: 9781489996190
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes model-based development of adaptive embedded systems, which enable improved functionality using the same resources. The techniques presented facilitate design from a higher level of abstraction, focusing on the problem domain rather than on the solution domain, thereby increasing development efficiency. Models are used to capture system specifications and to implement (manually or automatically) system functionality. The authors demonstrate the real impact of adaptivity on engineering of embedded systems by providing several industrial examples of the models used in the development of adaptive embedded systems. 320 pp. Englisch.