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Taschenbuch. Zustand: Neu. Neuware -Cassini At Saturn ¿ Huygens Results brings the story of the Cassini-Huygens mission and their joint exploration of the Saturnian system right up to date. Cassini entered orbit around Saturn June 2004 so this update includes 8 months of scientific data available for review, including the most spectacular images of Saturn, its rings and satellites ever obtained by a space mission. As the Cassini spacecraft approached its destination in spring 2004, the quality of the images already being returned by the spacecraft clearly demonstrated the spectacular nature of the close-range views that will be obtained. The book contains a 16-page colour section, comprising a carefully chosen selection of the most stunning images to be released during the spacecraft¿s initial period of operation.The Huygens craft, released by Cassini, parachuted through the clouds of Saturn¿s largest moon, Titan, in January 2005. David Harland tells the exciting story of the this craft¿s journey to the surface of one of the most enigmatic bodies on the Solar System, the only moon to have a dense atmosphere and possibly lakes of liquid gas at -190ºC on its surface. Titan is considered to be an early Earth in deep freeze, possibly with the building blocks of life in its atmosphere. There will undoubtedly be enormous interest in the first results and images of Titan¿s surface, and this book is the first incisive summary of this groundbreaking material.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 452 pp. Englisch.

Buch. Zustand: Neu. Neuware -Paperback features updated introductions and post-scriptFor more than twenty years globalization has been a prominent topic in the social sciences and humanities because it deals with processes that impact all societies at the international, national, and local levels. Controversies and conflicting approaches have dominated this field of studies. To understand the variety and strength of different approaches, the editor asked many of their leading exponents to outline their own ¿research framework¿.The book's contributors are world renowned experts in their field, including G. John Ikenberry, Michael Doyle, Layna Mosley, Alex Callinicos, Anthony McGrew, Thomas Risse, Roland Robertson, John Tomlinson, Saskia Sassen, David Held, Thomas Pogge, Chris Brown and Andrew Kuper.These writings have been organized into four sections: theoretical perspectives and cultural globalization, economic globalization, political globalization, and methodological approaches. The extensive coverage and the interdisciplinary flavor of the volume makes it suitable for a large interdisciplinary audience.¿Ino Rossi has assembled a stimulating collection of insightful essays by many of the world¿s leading analysts of globalization. The essays more than live up to the book¿s title, and the critical commentaries included in the volume, by the editor and other widely renowned contemporary social theorists, add a welcome dialogical dimension to the work. This is first-rate scholarship that merits careful reading by a wide audience.¿John Boli, Professor and Chair, Department of Sociology, Emory University, Atlanta, GA¿Many of the scholars in this volume were writing about political, social, and economic change from a global perspective long before the term ¿globalization¿ became so widely used. It is very useful to have their recent thoughts as well as that of some younger experts about where the world is going, and how tostudy this, all combined in a single, fascinating book.¿Daniel Chirot, University of Washington, Seattle, WA¿Rossi has assembled an array of leading experts to dissect globalization¿s realities and myths. Globalization emerges as a multi-dimensional process, structurally uneven, with deep measures of continuity and discontinuity from what went before. The global frontier has rarely been so penetratingly explored.¿Randall Collins, University of Pennsylvania¿In a compelling volume, pioneers who shaped globalization studies now take a fresh look at the field. This series of reflections deepens analysis and will help map research for many years to come.¿James H. Mittelman, Professor of International Relations, American University, Washington, DC, and Vice President of the International Studies AssociationSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 464 pp. Englisch.

Buch. Zustand: Neu. Neuware -Beautifully illustrated and engagingly written, Twelve Lectures in Quantum Mechanics presents theoretical physics with a breathtaking array of examples and anecdotes. Basdevant¿s style is clear and stimulating, in the manner of a brisk classroom lecture that students can follow with ease and enjoyment. Here is a sample of the book¿s style, from the opening of Chapter 1: 'If one were to ask a passer-by to quote a great formula of physics, chances are that the answer would be ¿E = mc2¿. In fact, of the three watershed years for physics toward the beginning of the 20th century ¿ 1905: the Special Relativity of Einstein, Lorentz and Poincaré; 1915: the General Relativity of Einstein, with its extraordinary reflections on gravitation, space and time; and 1925: the development of Quantum Mechanics ¿ it is surely the last which has the most profound implications for the development of science and technology. There is no way around it: all physics is quantum, from elementary particles, to stellar physics and the Big Bang, not to mention semiconductors and solar cells.'A graduate of the Ecole Normale Superieure, Jean-Louis Basdevant is Professor and Chair of the Department of Physics at the Ecole Polytechnique, and Director of Research for the CNRS. Specializing in the theoretical physics of elementary particles, quantum field theory and astrophysics, Prof. Basdevant works in the Leprince-Ringuet Laboratory at the Ecole Polytechnique.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 324 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Cerebral palsy is a lifelong condition that affects the individual, family, and immediate community. Therefore, the goal of allowing the individual with cerebral palsy to live life with the least impact of the disability requires c- plex attention to the individual and the family. Furthermore, society needs to be sensitive and to accommodate individuals with disabilities by limiting architectural impediments and providing accessible public transportation and communication. The educational system provides the key means for helping the individual prepare to function in society to his or her maximum ability. In many ways, the medical care system probably has the least sign- icant role in preparing the child with cerebral palsy to function optimally in society. However, the medical care system is the place where parents first learn that their child has developmental issues outside the expected norm. It is almost universally the place where parents also expect the child to be made normal in our modern society. In earlier times, the parents would expect healing to possibly come from the doctor, but also they would place hope for healing in religion. As this belief in spiritual or miraculous healing has - creased, a significant font of hope has decreased for parents of young ch- dren with disabilities.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 432 pp. Englisch.

Buch. Zustand: Neu. Neuware -Systemic Governance addresses accounting and accountability and develops conceptual tools to enhance the capacity of policy makers and managers. The structures and processes of international relations and governance need to be re-considered to allow diversity to the extent that is does not undermine the freedoms of others. The book makes a plea for systemic governance. Policy makers and managers need to work with rather than within theoretical and methodological frameworks to achieve multidimensional and multilayered policy decisions. Conceptual tools can be used to enhance systemic governance. The closest we can get to truth is through compassionate dialogue that explores paradoxes and considers the rights and responsibilities of caretakers. Case studies and conceptual tools enliven the text.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 488 pp. Englisch.

Buch. Zustand: Neu. Neuware -Except for one area of gene expression control, plant research has significantly fallen behind studies in insects and vertebrates. The advances made in animal gene expression control have benefited plant research, as we continue to find that much of the machinery and mechanisms controlling gene expression have been preserved in all eukaryotes. Through comparison, we have learned that certain aspects of gene regulation are shared by plants and animals, i.e. both contain introns separating the coding regions of most genes and both utilize similar machinery to process the introns to form mature mRNAs. Yet there are some interesting differences in gene structure and regulation between plants and animals. For example, unlike animal genes, plant genes are generally much smaller with fewer and smaller introns.Regulation of Gene Expression in Plants presents some of the most recent, novel and fascinating examples of transcriptional and posttranscriptional control of gene expression in plants and, where appropriate, provides comparison to notable examples of animal gene regulation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 220 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume begins with a tribute to Dr. Brian E. Conway by Dr. John O'M. Bockris, which is followed by six chapters. The topics covered are state of the art Polymer Electrolyte Membrane (PEM) fuel cell bipolar plates; use of graphs in electrochemical reaction networks; nano materials in lithium ion batteries; direct methanol fuel cells (two chapters); and the last chapter presents simulation of polymer electrolyte fuel cell catalyst layers. David and Valerie Bloomfield begin the first chapter with a discussion of the difficulties encountered when confronting bipolar plate development and state that the problems stem from the high corrosive nature of phosphoric acid. The water problems are mitigated but the oxidation problems increase. Bipolar plates are still not cheap, reliable or durable. In Chapter 2, Thomas Z. Fahidy reviews analysis of variance (ANOVA) and includes one way, two way, three way classification, and Latin squares observation methods. He moves on to a discussion of the applications of the analysis of covariance (ANCOVA) and goes over certain variables such as velocity, velocity and pressure drop, and product yields in a batch and flow electrolyzer. His conclusion is that proper statistical techniques are time savers which can save the experimenter and the process analyst considerable time and effort in trying to optimize the size ofstatistically meaningful experiments.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 376 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Forested landscapes have provided many important testing grounds for the devel- ment and application of landscape ecological principles and methods in North America. This central role of forests in landscape ecology emerged for several reasons. Forest cover is prominent in many regions of North America, from the temperate deciduous forests of the east to the coniferous forests of the north and west. Changes in forest spatial patterns are readily apparent to the human eye¿natural disturbances and timber harvests alter the arrangement of forest age classes across the landscape and this, in turn, influences many species and ecosystem processes; land-use changes have produced profound fluctuations in forest cover over several centuries; increasing re- dential development in rural areas is often concentrated within forests; and public lands include many forested landscapes. Management actions, such as varying the amount, size, and location of harvests, also represent landscape-scale ¿experiments¿ that provide valuable opportunities for study. Finally, forest patterns are readily detectable from remote imagery, and are thus amenable to study at broad scales. For these reasons, forests have provided motivation and many opportunities for studying the complex relationships between patterns and processes in many areas. The importance of landscape-level considerations in the management and c- servation of forested landscapes has become increasingly important, and a variety of stakeholders are involved.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Buch. Zustand: Neu. Neuware -The central goal of this book is to contribute to the timely discussion and understanding of Maya sacrifice and related posthumous body manipulation.Most school children in the US learn about the Maya and their practices based on their cultural and religious beliefs in their Social Studies classes. But a number of new sites have been discovered, giving an interdisciplinary group of researchers a channel to discuss these acts and their meaning.The editors bring together not only archaeologists but anthropologists, forensic anthropologists, art historians and bioarchaeologists, giving the volume a more complete perspective on these sites and the material culture and biological evidence found there.The field of archaeology is growing to include the physical remains of ritual practice along with the material remains and this book can be seen as an example of who the study of ancient civilizations can be more comprehensive. Additionally, this is an international volume with scholars from the area studied which is becoming more and more important in archaeological research. This will be of interest to students studying Mayan and Mesoamerican culture as well as those interested in bioarchaeology and human sacrifice.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 332 pp. Englisch.

Buch. Zustand: Neu. Neuware - Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Buch. Zustand: Neu. Neuware - Dr. Nina Persak's work addresses the criteria for criminalisation - that is, the criteria that should be employed in determinations whether to prohibit conduct through the criminal law. It is explicitly normative in approach, examining what should be the proper basis for criminalisation, rather than what factors legislatures actually tend to consider in adopting criminal prohibitions. Its focus is on the Harm Principle, that has been developed in Anglo-American philosophy of criminal law and on how this principal might illuminate the Continental debate on criminalisation. As such, this is a work on normative criminal law theory. Hitherto, there has existed no extended English-language treatment, comparing Anglo-American and Continental theories of criminalisation. An important strength of Dr. Persak's analysis lies in success in integrating themes from the two bodies of theory, the Anglo-American and the Con- nental. She begins with the Harm Principle and scrutinises its main criterion: the conduct's intrusion into the interests of other persons. She undertakes a careful dissection of this criterion: e.g., what constitutes 'harm' and what is the scope of 'others' (and whether and to what extent the latter includes collective interests). This discussion provides not only a thoughtful analysis of the Harm Principle itself; it also provides her with the basis of her critique, later in the volume, of Continental criminalisation theories.

Taschenbuch. Zustand: Neu. Neuware - Jugular vein and carotid artery cannulations are among the most widely used surgeries in research labs around the world. These cannulations are extremely important for confirmed intravenous delivery of test substances and arterial blood collection. Cannulation reduces the stress of multiple sampling as observed in association with tail vein or orbital sinus techniques (Ling, 2003; Flynn, 1988; Cocchetto, 1983). Very few adverse effects, including a possible rise of corticosterones and a decrease in platelets, are associated with indwelling catheters except under chronic conditions (Fagin, 1983; Richman, 1980).Typically, technicians teach these skills to incoming employees and move on to graduate studies or other fields. A resulting 'oral history' of cannulation has been passed down from technician to technician. I have endeavored to capture these techniques on paper. Through the years, I have searched for and collected a number of training materials and guides for teaching purposes. This is my attempt to compile all the necessary information in one source.The contents of this manual include two cannulation procedures detailed in a format of materials, instruction, and pictorial for each step. In addition, the manual is rounded out with information regarding procedures for anesthesia, pre- and post- operatives, anatomy, bleeding techniques using catheters implanted, and rat biodata compiled from numerous sources. The content is thoroughly researched and reported based on over 80 references and 7 reviewers' suggestions.

Buch. Zustand: Neu. Neuware - Over the past decade there has been an explosion of developments in mixed e ects models and their applications. This book concentrates on two major classes of mixed e ects models, linear mixed models and generalized linear mixed models, with the intention of o ering an up-to-date account of theory and methods in the analysis of these models as well as their applications in various elds. The rst two chapters are devoted to linear mixed models. We classify l- ear mixed models as Gaussian (linear) mixed models and non-Gaussian linear mixed models. There have been extensive studies in estimation in Gaussian mixed models as well as tests and con dence intervals. On the other hand, the literature on non-Gaussian linear mixed models is much less extensive, partially because of the di culties in inference about these models. However, non-Gaussian linear mixed models are important because, in practice, one is never certain that normality holds. This book o ers a systematic approach to inference about non-Gaussian linear mixed models. In particular, it has included recently developed methods, such as partially observed information, iterative weighted least squares, and jackknife in the context of mixed models. Other new methods introduced in this book include goodness-of- t tests, p- diction intervals, and mixed model selection. These are, of course, in addition to traditional topics such as maximum likelihood and restricted maximum likelihood in Gaussian mixed models.

Buch. Zustand: Neu. Neuware -REGULATION OF PROTEIN METABOLISM - M. Salinas and J. Burda.- CELL ADHESION MOLECULES OF THE IMMUNOGLOBULIN SUPERFAMILY IN THE NERVOUS SYSTEM - P. S. Walmod, M. V. Pedersen, V. Berezin, and E. Bock.- NEUROSECRETORY PROTEIN TRAFFICKING AND DENSE-CORE GRANULE BIOGENESIS IN NEUROENDOCRINE CELLS - T. Kim, M. Gondré-Lewis, I. Arnaoutova, N. Cawley, Y. Peng Loh.- PROTEIN SYNTHESIS AT SYNAPTIC SITES ON DENDRITES - O. Steward.- EMERGING FUNCTIONS OF THE 'CA2+ BUFFERS' PARVALBUMIN, CALBINDIN D-28k AND CALRETININ IN THE BRAIN - B. Schwaller.- ACTIN, ACTIN-BINDING PROTEINS AND MYOSINS IN NERVOUS SYSTEM - R. Ishikawa.- TRANSGLUTAMINASE - A. J. L. Cooper, S.-Y. Kim.- PROTEIN ALTERATION IN MENTAL RETARDATION - M. A. Junaid, W. T. Brown.- PROTEIN SULFATION - S. Hemmerich.- PROTEIN FOLDING - A. Szilágyi, J. Kardos, S. Osváth, L. Barna, and P. Závodszky.- NEURODEGENERATIVE DEMENTIAS INVOLVING ABERRANT PROTEIN AGGREGATION - T. Kudo and M. Takeda.- POLYGLUTAMINE DISEASES - H. Okazawa.- THE PROTEASOME, PROTEIN AGGREGATION, AND NEURODEGENERATION - S. Wilk.- SERINE PROTEASES - J. Tóth, P. Medveczky, L. Szilágyi, and L. Gráf.- CALPAIN AS A TARGET FOR PREVENTION OF NEURONAL DEATH IN INJURIES AND DISEASES OF THE CENTRAL NERVOUS SYSTEM - S. K. Ray, M. K. Guyton, E. A. Sribnick, and N. L. Banik.- SECRETASE PROCESSING OF AMYLOID PRECURSOR PROTEIN (APP) AND NEURODEGENERATION (APP) - N. Marks and M. J. Berg.- THE BIOLOGY OF CASPASES IN CENTRAL NERVOUS SYSTEM TRAUMA - M. L. McEwen, J. E. Springer.- MICROGLIAL PROTEASES - H. Nakanishi.- MMPs AND OTHER MATRIX-DEGRADING METALLOPROTEINASES IN NEUROLOGICAL DISEASE - P. E. Gottschall and K. Conant.- PROTEASE INHIBITORS AND THEIR INVOLVEMENT IN NEUROLOGICAL DISORDERS - B. Tizon and E. Levy.- NEUROPEPTIDASES - K.-S. Hui.- UBIQUITINATION AND PROTEASOMAL PROTEIN DEGRADATION IN NEURONS - L. Klimaschewski.- PROTEASE ACTIVITY IN THE AGING BRAIN - D. A. Gray.- FROM CONCEPT TO POTENTIAL THERAPEUTICS: NEUROPROTECTIVE PEPTIDES - I. Gozes and J. TiongSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 716 pp. Englisch.

Buch. Zustand: Neu. Neuware - Gene mapping is used in experimental genetics to improve the hardiness or productivity of animals or plants of agricultural value, to explore basic mechanisms of inheritance, or to study animal models of human inheritance. In human populations it is used as a first step to identify genes associated with human health and disease. This book presents a unified discussion of the statistical concepts applied in gene mapping, first in the experimental context of crosses of inbred lines and then in outbred populations, primarily humans. The development involves elementary principles of probability and statistics, which are implemented by computational tools based on the R programming language to simulate genetic experiments and evaluate statistical analyses. The viewpoint reflects the modern approach of using anonymous DNA markers distributed throughout the genome to identify regions likely to contain genes of interest. The reader is assumed to have some familiarity with probability/statistics and with elementary genetics. Important topics are reviewed in the first three chapters. The R programming language is developed in the text. Each chapter contains exercises, both theoretical and computational, some routine and others that are more challenging. The book is suitable for upper level undergraduate students or graduate students of genetics or statistics.

Buch. Zustand: Neu. Neuware - Ultra-wideband (UWB), short-pulse (SP) electromagnetics are now being used for an increasingly wide variety of applications, including collision avoidance radar, concealed object detection, and communications. Notable progress in UWB and SP technologies has been achieved by investigations of their theoretical bases and improvements in solid-state manufacturing, computers, and digitizers. UWB radar systems are also being used for mine clearing, oil pipeline inspections, archeology, geology, and electronic effects testing. Ultra-Wideband Short-Pulse Electromagnetics 7 presents selected papers of deep technical content and high scientific quality from the UWB-SP7 Conference, including wide-ranging contributions on electromagnetic theory, scattering, UWB antennas, UWB systems, ground penetrating radar (GPR), UWB communications, pulsed-power generation, time-domain computational electromagnetics, UWB compatibility, target detection and discrimination, propagation through dispersive media, and wavelet and multi-resolution techniques. This book serves as an essential for scientists and engineers working in these applications areas.

Buch. Zustand: Neu. Neuware -Prodrugs are substances administered in an inactive form that is then metabolized in the body in vivo into the active compound. The rationale behind administering prodrugs is to optimize absorption, distribution, metabolism, and excretion of these drugs. Since first described in the 1950s, prodrugs continue to be a fertile area of research. There are a number of small pharmaceutical/biotech companies dedicated to using prodrugs for the delivery of older but problematic drugs as well as to developing broad-based prodrug technologies for application to new and future drugs. These volumes represent a comprehensive guide to prodrugs and will guide the reader through the current status of the prodrug concept and its many applications and to highlight its many successes in overcoming formulation and delivery of problematic drugs.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1488 pp. Englisch.

Buch. Zustand: Neu. Neuware - In a very comprehensive way this book covers all aspects of high power diode laser technology for materials processing. Basics as well as new application oriented results obtained in a government funded national German research project are described in detail. Along the technological chain after a short introduction in the second chapter diode laser bar technology is discussed regarding structure, manufacturing technology and metrology. The third chapter illuminates all aspects of mounting and cooling, whereas chapter four gives wide spanning details on beam forming, beam guiding and beam combination, which are essential topics for incoherently coupled multi-emitter based high power diode lasers. Metrology, standards and safety aspects are the theme of chapter five. As an outcome of all the knowledge from chapter two to four various system configurations of high power diode lasers are described in chapter six; not only systems focussed on best available beam quality but especially also so called 'modular' set-ups are considered, where assemblies adapted to special applications are chosen. Finally, a wide field of applications, performed with the systems described in chapter six is described in chapter seven.