Springer us aug 2009 (14 Ergebnisse)
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cancer and aging are integrally related. Cancer incidence and mortality increase with age, with most cancer diagnoses and deaths occurring in patients aged 65 and older. The aging of the Baby Boomer population, along with an overall i…ncrease in life expectancy, points to a doubling of the U.S. population over age 65 by the year 2030. This demographic shift, combined with the known association of cancer and aging, is expected to bring about a rapid growth in the older cancer-patient population. It is clear that geriatric principles must become part of oncology care. The evaluation and development of treatment recommen- tions for an older adult with cancer can be challenging for many reasons. Tumor biology and response to therapy are affected by age. In addition, age-related factors may impact treatment patterns, tolerance, and efficacy. These age-related factors include functional status declines, comorbid conditions, changes in cognitive function, weakening of organ function, decreases in physiologic reserve, and faltering social support. 356 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This groundbreaking text has been established as the market leader throughout the world. Profusely illustrated, Transmission Electron Microscopy: A Textbook for Materials Science provides the necessary instructions for successful hands-on ap…plication of this versatile materials characterization technique. For this first new edition in 12 years, many sections have been completely rewritten with all others revised and updated. The new edition also includes an extensive collection of questions for the student, providing approximately 800 self-assessment questions and over 400 questions that are suitable for homework assignment. Four-color illustrations throughout also enhance the new edition. Praise for the first edition: `The best textbook for this audience available.' - American Scientist `Ideally suited to the needs of a graduate level course. It is hard to imagine this book not fulfilling most of the requirements of a text for such a course.' - Microscope `This book is written in such a comprehensive manner that it is understandable to all people who are trained in physical science and it will be useful both for the expert as well as the student.' - Micron `The book answers nearly any question - be it instrumental, practical, or theoretical - either directly or with an appropriate reference.This book provides a basic, clear-cut presentation of how transmission electron microscopes should be used and of how this depends specifically on one's specific undergoing project.' - MRS Bulletin, May 1998 `The only complete text now available which includes all the remarkable advances made in the field of TEM in the past 30-40 years.The authors can be proud of an enormous task, very well done.' - from the Foreword by Professor Gareth Thomas, University of California, Berkeley 840 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Data Mining and Multi agent Integration aims to re ect state of the art research and development of agent mining interaction and integration (for short, agent min ing). The book was motivated by increasing interest and work in the agents dat…a min ing, and vice versa. The interaction and integration comes about from the intrinsic challenges faced by agent technology and data mining respectively; for instance, multi agent systems face the problem of enhancing agent learning capability, and avoiding the uncertainty of self organization and intelligence emergence. Data min ing, if integrated into agent systems, can greatly enhance the learning skills of agents, and assist agents with predication of future states, thus initiating follow up action or intervention. The data mining community is now struggling with mining distributed, interactive and heterogeneous data sources. Agents can be used to man age such data sources for data access, monitoring, integration, and pattern merging from the infrastructure, gateway, message passing and pattern delivery perspectives. These two examples illustrate the potential of agent mining in handling challenges in respective communities. There is an excellent opportunity to create innovative, dual agent mining interac tion and integration technology, tools and systems which will deliver results in one new technology. 348 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -From Combinatorics to Philosophy: The Legacy of G. -C. Rota provides an assessment of G. -C. Rota's legacy to current international research issues in mathematics, philosophy and computer science.This volume includes chapters by leading rese…archers, as well as a number of invited research papers. Rota's legacy connects European and Italian research communities to the USA by providing inspiration to several generations of researchers in combinatorics, philosophy and computer science.From Combinatorics to Philosophy: The Legacy of G. -C. Rota is of valuable interest to research institutions and university libraries worldwide. This book is also designed for advanced-level students in mathematics, computer science, and philosophy. 280 pp. Englisch.
Sprache: Englisch
Verlag: Springer US Aug 2009, 2009
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Late Effects of Treatment for Brain Tumors reviews the development of the medical team's awareness of late effects of brain tumor treatment and an overview of brain tumor survivorship. It reviews the late effects by topic and by organ system…s, educates, and provides guidelines for follow up and interventions for patient survivorship. Advocacy for survivors and models for the importance of coordinated late effects programs are also discussed. 456 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Piezoelectricity has been a steadily growing field, with recent advances made by researchers from applied physics, acoustics, materials science, and engineering. This collective work presents a comprehensive treatment of selected advanced to…pics in the subject. Every chapter is self-contained and written by international experts who elaborate on special topics.Key features include:\* Systematic exposition of topics: from a brief summary of the 3-dimensional theory of linear piezoelectricity to selected topics within the linear theory; and the theory of small fields superposed on a finite bias;\* Provides a broad overview of piezoelectric (or electroelastic) materials such as single crystals and ceramics that play a key role in this innovative field; examples provided throughout;\*Treats new applications to piezoelectric materials and devices in electronics engineering and civil, mechanical, and aerospace engineering structure;\* Examines in detail numerical analysis methods to optimize the design of piezoelectric structures and devices.This book is written for an intermediate graduate level and is intended for researchers, mechanical engineers, and applied mathematicians interested in the advances of piezoelectricity and its new applications, and may be used as a supplemental text to a course where piezoelectricity is a focus.Also by Jiashi Yang: An Introduction to the Theory of Piezoelectricity, 2005 Springer, 978-0-387-23573-8. 344 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book pres…ents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions. 452 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse… perspectives¿basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins andvaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens¿ genomes provides opportunities that never before have been available¿identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated,replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process.The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 284 pp. Englisch.
Sprache: Englisch
Verlag: Springer US, Copernicus Aug 2009, 2009
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Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Late Effects of Treatment for Brain Tumors reviews the development of the medical team's awareness of late effects of brain tumor treatment and an overview of brain tumor survivorship. It reviews the late effects by topic and by organ systems, e…ducates, and provides guidelines for follow up and interventions for patient survivorship. Advocacy for survivors and models for the importance of coordinated late effects programs are also discussed.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 456 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The advances in computer entertainment, multi-player and online games, technology-enabled art, culture and performance have created a new form of entertainment and art. The success of this new field has influenced the development of the digi…tal entertainment industry and related products/services, which has impacted every aspect of our lives.Handbook of Multimedia for Digital Entertainment and Arts is an edited volume contributed by worldwide experts in the field of the new digital and interactive media, and their applications in entertainment and arts. This handbook covers leading edge media technologies, and the latest research applied to digital entertainment and arts. The main focus of Handbook of Multimedia for Digital Entertainment and Artstargets interactive and online games, edutainment, e-performance, personal broadcasting, innovative technologies for digital arts, digital visual and auditory media, augmented reality, moving media, and other advanced topics. The final chapters of this book present future trends and developments within this explosive field.Handbook of Multimedia for Digital Entertainment and Artsserves as a primary reference for advanced-level students, researchers and professors studying computer science and electrical engineering. With the dramatic growth of interactive digital entertainment and art applications, this handbook is also suitable as a reference for practitioners, programmers, and engineers working in this field. 769 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Algebraic Cryptanalysis bridges the gap between a course in cryptography, and being able to read the cryptanalytic literature. This book is divided into three parts: Part One covers the process of turning a cipher into a system of equations;… Part Two covers finite field linear algebra; Part Three covers the solution of Polynomial Systems of Equations, with a survey of the methods used in practice, including SAT-solvers and the methods of Nicolas Courtois.Topics include:Analytic Combinatorics, and its application to cryptanalysisThe equicomplexity of linear algebra operations Graph coloringFactoring integers via the quadratic sieve, with its applications to the cryptanalysis of RSAAlgebraic Cryptanalysis is designed for advanced-level students in computer science and mathematics as a secondary text or reference book for self-guided study. This book is suitable for researchers in Applied Abstract Algebra or Algebraic Geometry who wish to find more applied topics or practitioners working for security and communications companies. 392 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Algebraic Cryptanalysis bridges the gap between a course in cryptography, and being able to read the cryptanalytic literature. This book is divided into three parts: Part One covers the process of turning a cipher into a system of equations; Par…t Two covers finite field linear algebra; Part Three covers the solution of Polynomial Systems of Equations, with a survey of the methods used in practice, including SAT-solvers and the methods of Nicolas Courtois.Topics include:Analytic Combinatorics, and its application to cryptanalysisThe equicomplexity of linear algebra operationsGraph coloringFactoring integers via the quadratic sieve, with its applications to the cryptanalysis of RSAAlgebraic Cryptanalysis is designed for advanced-level students in computer science and mathematics as a secondary text or reference book for self-guided study. This book is suitable for researchers in Applied Abstract Algebra or Algebraic Geometry who wish to find more applied topics or practitioners working for security and communications companies.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Due to its rapid development in recent years, hematopathology has become a very complicated discipline. The current development is mainly in two aspects: the new classification of lymphomas and leukemias and the new techniques.The Revised Eu…ropean-American Classification of Lymphoid Neoplasms (REAL classification) and the World Health Organization (WHO) classification of hematologic neoplasms require not only morphologic criteria but also immunophenotyping and molecular genetics for the diagnosis of hematologic tumors. Immunophenotyping is performed by either flow cytometry or immunohistochemistry. There are many new monoclonal antibodies and new equipments accumulated in recent years that make immunophenotyping more or more accurate and helpful. There are even more new techniques invented in recent years in the field of molecular genetics. In cytogenetics, the conventional karyotype is supplemented and partly replaced by the fluorescence in situ hybridization (FISH) technique. The current development of gene expression profiling is even more powerful in terms of subtyping the hematologic tumors, which may help guiding the treatment and predict the prognosis. In molecular biology, the tedious Southern blotting technique is largely replaced by polymerase chain reaction (PCR). The recent development in reverse-transcriptase PCR and quantitative PCR makes these techniques even more versatile. Because of these new developments, hematopathology has become too complicated to handle by a general pathologist. Many hospitals have to hire a newly trained hematopathologist to oversee peripheral blood, bone marrow and lymph node examinations. These young hematopathologists are geared to the new techniques, but most of them are inexperienced in morphology. No matter how well-trained a hematopathologist is, he or she still needs to see enough cases so that they can recognize the morphology and use the new techniques to substantiate the diagnosis. In other words, morphology is still the basis for the diagnosis of lymphomas and leukemias.Therefore, a good color atlas is the most helpful tool for these young hematopathologists and for the surgical pathologists who may encounter a few cases of hematologic tumors from time to time. In a busy daily practice, it is difficult to refer to a comprehensive hematologic textbook all the time. There are a few hematologic color atlases on the market to show the morphology of the normal blood cells and hematologic tumor cells. These books are helpful but not enough, because tumor cell morphology is variable from case to case and different kinds of tumor cells may look alike and need to be differentiated by other parameters. The best way to learn morphology is through the format of clinical case study. This format is also consistent with the daily practice of hematopathologists and with the pattern in all the specialty board examinations. Therefore, it is a good learning tool for the pathology residents, hematology fellows as well as medical students. This proposed book will present 83 clinical cases with clinical history, morphology of the original specimen and a list of differential diagnoses. This is followed by further testing with pictures to show the test results. At the end, a correct diagnosis is rendered with subsequent brief discussion on how the diagnosis is achieved. A few useful references will be cited and a table will be provided for differential diagnosis in some cases. The major emphasis is the provision of 500 color photos of peripheral blood smears, bone marrow aspirates, core biopsy, lymph node biopsy and biopsies of other solid organs that are involved with lymphomas and leukemias. Pictures of other diagnostic parameters, such as flow cytometric histograms, immunohistochemical stains, cytogenetic karyotypes, fluorescence in situ hybridization and polymerase chain reaction, will also be included.A comprehensive approach.
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EUR 320,99
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Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Due to its rapid development in recent years, hematopathology has become a very complicated discipline. The current development is mainly in two aspects: the new classification of lymphomas and leukemias and the new techniques.The Revised Europe…an-American Classification of Lymphoid Neoplasms (REAL classification) and the World Health Organization (WHO) classification of hematologic neoplasms require not only morphologic criteria but also immunophenotyping and molecular genetics for the diagnosis of hematologic tumors. Immunophenotyping is performed by either flow cytometry or immunohistochemistry. There are many new monoclonal antibodies and new equipments accumulated in recent years that make immunophenotyping more or more accurate and helpful. There are even more new techniques invented in recent years in the field of molecular genetics. In cytogenetics, the conventional karyotype is supplemented and partly replaced by the fluorescence in situ hybridization (FISH) technique. The current development of gene expression profiling is even more powerful in terms of subtyping the hematologic tumors, which may help guiding the treatment and predict the prognosis. In molecular biology, the tedious Southern blotting technique is largely replaced by polymerase chain reaction (PCR). The recent development in reverse-transcriptase PCR and quantitative PCR makes these techniques even more versatile.Because of these new developments, hematopathology has become too complicated to handle by a general pathologist. Many hospitals have to hire a newly trained hematopathologist to oversee peripheral blood, bone marrow and lymph node examinations. These young hematopathologists are geared to the new techniques, but most of them are inexperienced in morphology. No matter how well-trained a hematopathologist is, he or she still needs to see enough cases so that they can recognize the morphology and use the new techniques to substantiate the diagnosis. In other words, morphology is still the basis for the diagnosis of lymphomas and leukemias.Therefore, a good color atlas is the most helpful tool for these young hematopathologists and for the surgical pathologists who may encounter a few cases of hematologic tumors from time to time. In a busy daily practice, it is difficult to refer to a comprehensive hematologic textbook all the time. There are a few hematologic color atlases on the market to show the morphology of the normal blood cells and hematologic tumor cells. These books are helpful but not enough, because tumor cell morphology is variable from case to case and different kinds of tumor cells may look alike and need to be differentiated by other parameters.The best way to learn morphology is through the format of clinical case study. This format is also consistent with the daily practice of hematopathologists and with the pattern in all the specialty board examinations. Therefore, it is a good learning tool for the pathology residents, hematology fellows as well as medical students.This proposed book will present 83 clinical cases with clinical history, morphology of the original specimen and a list of differential diagnoses. This is followed by further testing with pictures to show the test results. At the end, a correct diagnosis is rendered with subsequent brief discussion on how the diagnosis is achieved. A few useful references will be cited and a table will be provided for differential diagnosis in some cases.The major emphasis is the provision of 500 color photos of peripheral blood smears, bone marrow aspirates, core biopsy, lymph node biopsy and biopsies of other solid organs that are involved with lymphomas and leukemias. Pictures of other diagnostic parameters, such as flow cytometric histograms, immunohistochemical stains, cytogenetic karyotypes, fluorescence in situ hybridization and polymerSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 540 pp. Englisch.
