springer us dez 2008 (101 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware -The First Soviet Cosmonaut Team will relate who these men were and offer far more extensive background stories, in addition to those of the more familiar names of early Soviet space explorers from that group. Many previously-unpublished photographs of these ¿missing¿ candidates will also be included for the first time in this book. It will be a detailed, but highly readable and balanced account of the history, training and experiences of the first group of twenty cosmonauts of the USSR. A covert recruitment and selection process was set in motion throughout the Soviet military in August 1959, just prior to the naming of Americäs Mercury astronauts. Those selected were ordered to report for training at a special camp outside of Moscow in the spring of 1960. Just a year later, Senior Lieutenant Yuri Gagarin of the Soviet Air Force (promoted in flight to the rank of major) was launched aboard a Vostok spacecraft and became the first person ever to achieve space flight and orbit the Earth.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 436 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Molecular Pathology in Clinical Practice: Infectious Diseases is an authoritative and comprehensive guide that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular infectious disease testing. The book integrates the latest advancements in the field with the basic principles and practical applications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 180 pp. Englisch.

Buch. Zustand: Neu. Neuware -Historically, for metric spaces the quest for universal spaces in dimension theory spanned approximately a century of mathematical research. The history breaks naturally into two periods - the classical (separable metric) and the modern (not-necessarily separable metric).The classical theory is now well documented in several books. This monograph is the first book to unify the modern theory from 1960-2007. Like the classical theory, the modern theory fundamentally involves the unit interval.Unique features include:\* The use of graphics to illustrate the fractal view of these spaces;\* Lucid coverage of a range of topics including point-set topology and mapping theory, fractal geometry, and algebraic topology;\* A final chapter contains surveys and provides historical context for related research that includes other imbedding theorems, graph theory, and closed imbeddings;\* Each chapter contains a comment section that provides historical context with references that serve as a bridge to the literature.This monograph will be useful to topologists, to mathematicians working in fractal geometry, and to historians of mathematics. Being the first monograph to focus on the connection between generalized fractals and universal spaces in dimension theory, it will be a natural text for graduate seminars or self-study - the interested reader will find many relevant open problems which will create further research into these topics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 272 pp. Englisch.

Buch. Zustand: Neu. Neuware -The literature of the behavioural and social sciences is full of theory and research on learning and memory. Teaching is comparatively a stepchild, neglected by those who have built a formidable body of theories of learning and memory. However, teaching is where learning and memory theory should pay off.'A Conception of Teaching' dedicates a chapter to each of the following important components: the need for a theory; the possibility of a theory; the evolution of a paradigm for the study of teaching; a conception of the process of teaching; a conception of the content of teaching; a conception of students¿ cognitive capabilities and motivations; a conception of classroom management; and the integration of these conceptions.Written in a highly accessible style, while maintaining a base in research, Dr. Nathaniel L. Gage presents 'A Conception of Teaching' with clarity and well situated within current educational debates.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 196 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Oscar Zariski¿s work in mathematics permanently altered the foundations of algebraic geometry. The powerful tools he forged from the ideas of modern algebra allowed him to penetrate classical problems with an unaccustomed depth, and brought new rigor to the intuitive proofs of the Italian School. The students he trained at Hopkins, and later at Harvard, are among the foremost mathematicians of our time.While what he called his ¿real life¿ is recorded in almost a hundred books and papers, this story of his ¿unreal life¿ is based upon Parikh¿s interviews with his family, colleagues, and students, and on his own memories from a series of tape-recorded interviews made a few years before his death in 1986.First published in 1991, The Unreal Life of Oscar Zariski was highly successful and widely praised, but has been out of print for many years. Springer is proud to make this book available again, introducing Oscar Zariski to a new generation of mathematicians.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 216 pp. Englisch.

Buch. Zustand: Neu. Neuware -Proportional Optimization and Fairness is a long-needed attempt to reconcile optimization with apportionment in just-in-time (JIT) sequences and find the common ground in solving problems ranging from sequencing mixed-model just-in-time assembly lines through just-in-time batch production, balancing workloads in event graphs to bandwidth allocation internet gateways and resource allocation in computer operating systems. The book argues that apportionment theory and optimization based on deviation functions provide natural benchmarks for a process, and then looks at the recent research and developments in the field.Individual chapters look at the theory of apportionment and just-in-time sequences; minimization of just-in-time sequence deviation; optimality of cyclic sequences and the oneness; bottleneck minimization; competition-free instances, Fraenkel¿s Conjecture, and optimal admission sequences; response time variability; applications to the Liu-Layland Problem and pinwheel scheduling; temporal capacity constraints and supply chain balancing; fair queuing and stride scheduling; and smoothing and batching.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 312 pp. Englisch.

Buch. Zustand: Neu. Neuware -In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected.The aim of this book is to provide one of the first (if not the first) detailed views of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

Buch. Zustand: Neu. Neuware -The present volume is a collective monograph devoted to applications of the optimal design theory in optimization and statistics. The chapters re ect the topics discussed at the workshop ¿W-Optimum Design and Related Statistical Issues¿ that took place in Juan-les-Pins, France, in May 2005. The title of the workshop was chosen as a light-hearted celebration of the work of Henry Wynn. It was supported by the Laboratoire I3S (CNRS/Universit¿ e de Nice, Sophia Antipolis), to which Henry is a frequent visitor. The topics covered partly re ect the wide spectrum of Henry¿s research - terests. Algorithms for constructing optimal designs are discussed in Chap. 1, where Henry¿s contribution to the eld is acknowledged. Steepest-ascent - gorithms used to construct optimal designs are very much related to general gradientalgorithmsforconvexoptimization. Inthelasttenyears,asigni cant part of Henry¿s research was devoted to the study of the asymptotic prop- ties of such algorithms. This topic is covered by Chaps. 2 and 3. The work by Alessandra Giovagnoli concentrates on the use of majorization and stoch- tic ordering, and Chap. 4 is a hopeful renewal of their collaboration. One of Henry¿s major recent interests is what is now called algebraic statistics, the application of computational commutative algebra to statistics, and he was partly responsible for introducing the experimental design sub-area, reviewed in Chap. 5. One other sub-area is the application to Bayesian networks and Chap. 6 covers this, with Chap. 7 being strongly related.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Molecular Pathology Testing in Clinical Practice: Genetics is an authoritative and comprehensive guide that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular genetic testing. The book integrates the latest advancements in the field with the basic principles and practical applications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 328 pp. Englisch.

Buch. Zustand: Neu. Neuware -. . . . . . . . . . . . . . . . . 25 2. 9 Analytic De nition for Quasiconformality. . . . . . . . . . . . . . . . . . . . . . 31 n 2. 10 R as a Loewner Space . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 2. 11 Quasisymmetry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 3 Moduli and Domains . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 3. 1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 3. 2 QED Exceptional Sets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 3. 3 QED Domains and Their Properties . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 3. 4 UniformandQuasicircleDomains . . . . . . . . . . . . . . . . . . . . . . . . . . . .Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 380 pp. Englisch.

Buch. Zustand: Neu. Neuware -Research on Secure Key Establishment has become very active within the last few years. Secure Key Establishment discusses the problems encountered in this field. This book also introduces several improved protocols with new proofs of security.Secure Key Establishment identifies several variants of the key sharing requirement. Several variants of the widely accepted Bellare and Rogaway (1993) model are covered. A comparative study of the relative strengths of security notions between these variants of the Bellare¿Rogaway model and the Canetti¿Krawczyk model is included. An integrative framework is proposed that allows protocols to be analyzed in a modified version of the Bellare¿Rogaway model using the automated model checker tool.Secure Key Establishment is designed for advanced level students in computer science and mathematics, as a secondary text or reference book. This book is also suitable for practitioners and researchers working for defense agencies or security companies.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 236 pp. Englisch.

Buch. Zustand: Neu. Neuware -Machining of Polymer Matrix Composites will serve as an indispensable reference/source book for process design, tool and production engineers in composite manufacturing. This book provides the reader with a comprehensive scientific treatment of the theory of machining as it applies to fiber reinforced polymer composites, covers the latest technical advances in the area of machining and tooling and discusses the applications of fiber reinforced polymer composites as they are used in the aircraft and automotive manufacturing industries.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 328 pp. Englisch.

Buch. Zustand: Neu. Neuware -Genetic Programming Theory and Practice VI was developed from the sixth workshop at the University of Michigan¿s Center for the Study of Complex Systems to facilitate the exchange of ideas and information related to the rapidly advancing field of Genetic Programming (GP). Contributions from the foremost international researchers and practitioners in the GP arena examine the similarities and differences between theoretical and empirical results on real-world problems. The text explores the synergy between theory and practice, producing a comprehensive view of the state of the art in GP application.These contributions address several significant interdependent themes which emerged from this year¿s workshop, including: (1) Making efficient and effective use of test data. (2) Sustaining the long-term evolvability of our GP systems. (3) Exploiting discovered subsolutions for reuse. (4) Increasing the role of a Domain Expert.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.

Buch. Zustand: Neu. Neuware -The principal chapters of this book form a collection of technical articles sp- ning many areas of research in robotics, these are followed by a set of short r- iniscences and tributes written by former students of Professor George A. Bekey. Professor Bekey, a pioneer in robotics, retired from the University of Southern C- ifornia (USC) in 2002 after serving on its faculty for forty years. He maintains an association with USC as University Professor Emeritus. Professor Bekey turned 80 in June 2008 - this is his Festschrift. As one of Professor Bekey¿s former students, it has been my privilege to know him for many years. This book represents the collective warm feelings of his former students, who remember their association with him in the fondest terms. Part I of this book is composed of technical chapters representing threads of active robotics research knitted loosely together. In many cases the themes of the chapters have their origins in the work the authors did when they were graduate students with Professor Bekey. These chapters are written for the reader interested in a sampling of modern research in Autonomous Robots. It is my hope that, for the serious reader, these chapters will serve as invitations to explore the eld via further reading and research.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 196 pp. Englisch.

Buch. Zustand: Neu. Neuware -Grids are a crucial enabling technology for scientific and industrial development. Grid and Services Evolution, the 11th edited volume of the CoreGRID series, was based on The CoreGRID Middleware Workshop, held in Barcelona, Spain, June 5-6, 2008.Grid and Services Evolution provides a bridge between the application community and the developers of middleware services, especially in terms of parallel computing. This edited volume brings together a critical mass of well-established researchers worldwide, from forty-two institutions active in the fields of distributed systems and middleware, programming models, algorithms, tools and environments.Grid and Services Evolution is designed for a professional audience composed of researchers and practitioners within the Grid community industry. This volume is also suitable for advanced-level students in computer science.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

Buch. Zustand: Neu. Neuware -As cyberspace continues to rapidly expand, its infrastructure is now an in- gral part of the world's economy and social structure. Given this increasing int- connectivity and interdependence, what progress has been made in developing an ecosystem of safety and security This study is the second phase of an initial - tempt to survey and catalog the multitude of emerging organizations promoting global initiatives to secure cyberspace. The authors provide a breakdown and analysis of organizations by type, - cluding international, regional, private-public, and non-governmental organi- tions. Concluding with a discussion of the progress made in recent years, the study explores current trends regarding the effectiveness and scope of coverage provided by these organizations and addresses several questions concerning the overall state of international cyber security. The authors would like to thank Mr. Anthony Rutkowski for generously p- viding his time, guidance, and support. The authors would also like to thank the International Telecommunication Union (ITU) Telecommunication Development Sector (ITU-D) and the United States National Science Foundation (NSF Grant R3772) for partially supporting the research conducted in this study. In addition, the authors would like to thank the Georgia Institute of Technology¿s Center for International Strategy, Technology, and Policy (CISTP) for assistance in hosting the Cyber Security Organization Catalog, and the Georgia Tech Information Se- rity Center (GTISC) for cooperation and promotion of this study. Table of Contents 1 The International Landscape of Cyber Security . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2 A Brief History of Global Responses to Cyber Threats . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 176 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Procedure and Techniques The aortic valve in these patients is most often The dilation can be approached from either a myxomatous and bicuspid with a single, fused retrograde or antegrade direction. Remember commissure and an eccentrically placed orifice, that critical AS is a case of millimeters¿so you or unicuspid (dome-shaped). The valve annulus need to be meticulous. may be small for age, but there is evidence that following dilation even quite small annuli may grow to a normal or near normal dimension (1). Retrograde Approach Myxomatous valves may mature, as Myxo- tous pulmonary valves. Because there is a spec- This is the more common approach at Children¿s trum to left-sided obstructive lesions, often the Hospital Boston since the production of l- first decision in many of these patients is whether profile balloons. Often the umbilical artery and they should have a valvotomy or a staged o- vein already have been cannulated, and may be ventricle repair.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -Molecular Pathology in Clinical Practice: Oncology is an authoritative and comprehensive guide that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular oncology testing. It addresses all areas of molecular oncology testing including: molecular biology basics, inherited cancers, solid tumors, neoplastic hematopathology, identity testing and laboratory management. The book integrates the latest advancements in the field with the basic principles and practical applications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 300 pp. Englisch.

Buch. Zustand: Neu. Neuware -Mechanical engineering,and engineering discipline born of the needs of the industrial revolution, is once again asked to do its substantial share in the call for industrial renewal. The general call is urgent as we face p- found issues of productivity and competitiveness that require engineering solutions, among others. The Mechanical Engineering Series is a series f- turing graduate texts and research monographs intended to address the need for information in contemporary areas of mechanical engineering. The series is conceived as a comprehensive one that covers a broad range of concentrations important to mechanical engineering graduate - ucation and research. We are fortunate to have a distinguished roster of series editors, each an expert in one of the areas of concentration. The names of the series editors are listed on page vi of this volume. The areas of concentration are applied mechanics, biomechanics, computational - chanics, dynamic systems and control, energetics, mechanics of materials, processing, thermal science, and tribology. Preface After15yearssincethepublicationofVibrationofStructuresandMachine s and three subsequent editions a deep reorganization and updating of the material was felt necessary. This new book on the subject of Vibration dynamics and control is organized in a larger number of shorter chapters, hoping that this can be helpful to the reader. New materialhas been added and many points have been updated. A larger number of examples and of exercises have been included.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 884 pp. Englisch.

Buch. Zustand: Neu. Neuware - This is a book about the ambitious reform strategy known as mayoral control ini- ated to transform the dysfunctional system of urban education in the United States. I use the term dysfunctional to refer to the inability of urban school districts over the past 50 years to reduce the learning gap between poor students and their middle class peers, despite a host of reform efforts including desegregation, compensatory programs, and decentralization. Since the mid-1990s, the idea of mayoral control has generated considerable interest. Several large cities have introduced it such as Boston, Chicago, Cleveland, Detroit, Baltimore, and Washington (Henig and Rich 2004; Wong et al. 2007). Although the latter have completed a quantitative study of mayoral control's impact on student performance in over 100 cities, a case study of the New York experience nevertheless illuminates the capacity of this tool for transforming urban education. Because of the size of the NYC system - roughly 1.2 million students - and its economic, social, and ethnic diversity, it faces the myriad problems of urban edu- tion writ large that impede efforts to implement change in these schools.

Buch. Zustand: Neu. Neuware -Course covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections.This conference is being supported by several societies and is sponsored by several pharmaceutical companies, such as Aventis, Baxter, Chiron Vaccines, Wyeth, etc.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 280 pp. Englisch.

Buch. Zustand: Neu. Neuware -Game Theoretic Risk Analysis of Security Threats introduces reliability and risk analysis in the face of threats by intelligent agents. More specifically, game-theoretic models are developed for identifying optimal and/or equilibrium defense and attack strategies in systems of varying degrees of complexity. The book covers applications to networks, including problems in both telecommunications and transportation. However, the book¿s primary focus is to integrate game theory and reliability methodologies into a set of techniques to predict, detect, diminish, and stop intentional attacks at targets that vary in complexity. In this book, Bier and Azaiez highlight work by researchers who combine reliability and risk analysis with game theory methods to create a set of functional tools that can be used to offset intentional, intelligent threats (including threats of terrorism and war). These tools will help to address problems of global security and facilitate more cost-effective defensive investments.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 248 pp. Englisch.

Buch. Zustand: Neu. Neuware -Information Systems Development (ISD) progresses rapidly, continually creating new challenges for the professionals involved. New concepts, approaches and techniques of systems development emerge constantly in this field. Progress in ISD comes from research as well as from practice.This conference will discuss issues pertaining to information systems development (ISD) in the inter-networked digital economy. Participants will include researchers, both experienced and novice, from industry and academia, as well as students and practitioners. Themes will include methods and approaches for ISD; ISD education; philosophical, ethical, and sociological aspects of ISD; as well as specialized tracks such as: distributed software development, ISD and knowledge management, ISD and electronic business / electronic government, ISD in public sector organizations, IOS.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 624 pp. Englisch.

Buch. Zustand: Neu. Neuware -The major problem facing new energy conversion and storage technologies remains device ef ciency. Projects based on nanostructured materials can yield improved performance in devices involving electrochemical reactions and heterogeneous catalysis, such as fuel and solar cells, batteries, etc. Nanoscale structures drama- cally alter the surface reaction rates and electrical transport throughout the material, causing a dramatic improvement in energy storage, conversion, and generation. Furthermore, the design of nanoscale materials to be applied in alternative energy devices is a predictable way to develop a wide range of new technologies for a more sustainable future. Therefore, the goal of this book is to present basic fundamentals and the most relevant properties of nanostructured materials in order to improve alternative energy devices. This book begins with a chapter by Gratzel ¿ summarizing the use of mesoscopic thin lms and hybrid materials in the development of new kinds of regenerative photoelectrochemical devices. Applications include high-ef ciency solar cells. In chapter two, Ribeiro and Leite describe assembly and properties of nanop- ticles. The chapter presents a review on the properties and main features of nanoscale materials, emphasizing the dependence of key properties on size for energy purposes. A general description is also given of nanoparticle synthesi- tion methods (mainly oxides), focusing on advances in tailoring controlled shape nanostructures.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

Buch. Zustand: Neu. Neuware -Service-Oriented Computing is one of the most promising software engineering trends for future distributed systems. Currently there are many different approaches to semantic web service descriptions and many frameworks built around them. Yet a common understanding, evaluation scheme, and test bed to compare and classify these frameworks in terms of their abilities and shortcomings, is still missing.Semantic Web Services Challenge is an edited volume that develops this common understanding of the various technologies intended to facilitate the automation of mediation, choreography and discovery for Web Services using semantic annotations.Semantic Web Services Challenge is designed for a professional audience composed of practitioners and researchers in industry. Professionals can use this book to evaluate SWS technology for their potential practical use. The book is also suitable for advanced-level students in computer science.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 312 pp. Englisch.

Buch. Zustand: Neu. Neuware -Dale's Principle postulated that a neuron functions as a metabolic unit, whereby a process occurring in the cell can influence all of the compartments of that given neuron. This was unfortunately transformed in the literature to a principle stating that ¿a single cell releases only one neurotransmitter¿. Until recently, this has influenced many neuroscientists to consider with skepticism the idea that classical neurotransmitters could be co-released from neurons.It is now clear that the ¿one neuron, one neurotransmitter¿ postulate is the exception rather than the rule. The aim of this book is to gather the available evidence, provided by the authors that have discovered and studied the co-existence or co-release of several pairs of neurotransmitters, in several neural networks. It will provide a timely overview of a mechanism of neural communication that is likely to attract increasing attention of the neuroscientific community.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 304 pp. Englisch.

Buch. Zustand: Neu. Neuware -The Primality Testing Problem (PTP) has now proved to be solvable in deterministic polynomial-time (P) by the AKS (Agrawal-Kayal-Saxena) algorithm, whereas the Integer Factorization Problem (IFP) still remains unsolvable in (P). There is still no polynomial-time algorithm for IFP. Many practical public-key cryptosystems and protocols such as RSA (Rivest-Shamir-Adleman) rely their security on computational intractability of IFP.Primality Testing and Integer Factorization in Public Key Cryptography, Second Edition, provides a survey of recent progress in primality testing and integer factorization, with implications to factoring based public key cryptography. Notable new features are the comparison of Rabin-Miller probabilistic test in RP, Atkin-Morain elliptic curve test in ZPP and AKS deterministic test.This volume is designed for advanced level students in computer science and mathematics, and as a secondary text or reference book; suitable for practitioners and researchers in industry.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

Buch. Zustand: Neu. Neuware -Handbook of Optimization in Medicine is devoted to examining the dramatic increase in the application of effective optimization techniques to the delivery of health care. The articles, written by experts from the areas of operations research, computer science, and medicine, focus on models and algorithms that have led to more efficient and sophisticated treatments of patients.Topics covered include: optimization in medical imaging, classification and data mining with medical applications, treatment of epilepsy and other brain disorders, treatment of head-and-neck, prostate, and other cancers using conventional conformal and intensity-modulated radiation therapy as well as proton therapy, treatment selection for breast cancer based on new classification schemes, optimization for the genome project, optimal timing of organ transplants.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 460 pp. Englisch.

Buch. Zustand: Neu. Neuware -Hormone Receptors in Breast Cancer provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist. Advances in basic science of molecular endocrinology have undoubtedly been translated into clinical practice, and clinicians caring for this disease need to be knowledgeable about these developments. The molecular basis of hormone action has been elucidated, and the relative significance of the different estrogen and progesterone receptor isoforms has been explored. This explosion of information has lead to exciting new areas of gene specific targeting of the disease, and breast cancer prevention. Paradigm shifts in treatment options and sequencing have recently occurred in breast cancer management, necessitating close cooperation and communication between translational scientists and physicians. This book is focused on providing this communication.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 292 pp. Englisch.

Buch. Zustand: Neu. Neuware -The dogmas of the quiet past are inadequate to the stormy present. The occasion is piled high with difficulty, and we must rise with the occasion. As our case is new, so we must think anew and act anew. Abraham Lincoln, 1862 When I came across this quote, it made me recall my first participation at an international meeting on bone marrow transplantation, at a time when this was the only term that was used to describe the field. During a particular session there was a presentation on the use of peripheral blood as the sole source of stem cells for transplantation, and a member of the audience rose to state that it was medically unethical to consider such treatment, as it certainly could not contain stem cells. Now nearly twenty years later, peripheral blood is the predominant source of stem cells used for hematopoietic stem cell transplantation. In the same period of time there have been several other dogmatic opinions, which permeate all of medicine, that have come and gone in the field of hematopoietic stem cell transplantation, and will continue to do so with advancements from basic and clinical research. It is within this context that the format of this book was devised. Traditionally reviews on specific topics related to hematopoietic stem cell transplantation reflect the views of a single author or a research group.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 608 pp. Englisch.