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Taschenbuch. Zustand: Neu. Neuware -Despite an enormous investment of effort throughout the world, cancer is still a major barrier to human longevity. Cancer deaths are estimated to be more than five million globally. Currently responsible for about 20% of all deaths in developed coun tries, the burden of cancer is steadily incr…easing in the developing world, following the control of malnutrition and infectious and parasitic diseases. Deeply impressed by the report of the Symposium on Geographic Pathology and Demography of Cancer held at Oxford in 1950, and through his preliminary work on cancer mortality statistics in Japan, Professor M. Segi decided to devote his life to the fight against cancer by establishing worldwide comparative cancer statistics-one of the landmarks in cancer studies and in cancer prevention strategies. He and his associates published six volumes of Cancer Mortality in 24 Countries with reliable mortality statistics covering 1950-1967, using the world population which he had derived as a standard. These publications rapidly became standard works of reference on the subject throughout the world. Professor Segi was a pioneer of cancer epidemiology in Japan. He cleaved a path through the jungle of cancer using epidemiological methods. By promoting cancer studies, he overcame the poor understanding of malignant disease which existed after World War II, when cancer mortality rates were still low.
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Taschenbuch. Zustand: Neu. Neuware -This volume of essays grew out of a symposium organized by Judith Hoch-Smith and Anita Spring for the 1974 American Anthropological Association meetings in Mexico City. The two-part symposium was enti tled 'Women in Ritual and Symbolic Systems: I. Midwives, Madonnas, and Mediums; ll. Prostitut…es, Witches, and Androgynes. ' The sym posium participants were asked to explore theological, ritual, and sym bolic aspects-both positive and negative-of the feminine cultural do main, using ethnographic materials with which they were familiar. The resulting papers have been revised, edited, and gathered together in Women in Ritual and Symbolic Roles. The theoretical importance of these papers for the study of women's participation in culture and society rests on the assumption that reli gious ideas are paramount forces in social life, that relationships be tween the sexes, the nature of female sexuality, and the social and cul tural roles of women are in large part defined by religious ideas. That this proposition remains valid long after religion itself has ceased to be a living truth in the lives of many people can be seen from the tenacious ness of Judeo-Christian ideas about women in the contemporary West ern world. Both the expansion of life options for women and the creation of more positive cultural images of the female are intimately related to changes in the my tho-symbolic portraits that people carry around in their heads. These portraits are almost exclusively constructed from mythological and religious conceptions inherent in all facets of culture.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.
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Taschenbuch. Zustand: Neu. Neuware - Despite an enormous investment of effort throughout the world, cancer is still a major barrier to human longevity. Cancer deaths are estimated to be more than five million globally. Currently responsible for about 20% of all deaths in developed coun tries, the burden of cancer is steadily inc…reasing in the developing world, following the control of malnutrition and infectious and parasitic diseases. Deeply impressed by the report of the Symposium on Geographic Pathology and Demography of Cancer held at Oxford in 1950, and through his preliminary work on cancer mortality statistics in Japan, Professor M. Segi decided to devote his life to the fight against cancer by establishing worldwide comparative cancer statistics-one of the landmarks in cancer studies and in cancer prevention strategies. He and his associates published six volumes of Cancer Mortality in 24 Countries with reliable mortality statistics covering 1950-1967, using the world population which he had derived as a standard. These publications rapidly became standard works of reference on the subject throughout the world. Professor Segi was a pioneer of cancer epidemiology in Japan. He cleaved a path through the jungle of cancer using epidemiological methods. By promoting cancer studies, he overcame the poor understanding of malignant disease which existed after World War II, when cancer mortality rates were still low.
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Taschenbuch. Zustand: Neu. Neuware - 1 The Chondrodystrophies.- Classification of the Chondrodystrophies.- Evaluation of the Dwarfed Patient.- Clinical, Radiographic, Genetic, and Pathological Features of the Chondrodystrophies.- Animal Models of the Chondrodystrophies.- Future Trends in Chondrodystrophy Research.- 2 New Techniq…ues in the Study of Human Chromosomes: Methods and Applications.- Fluorescence Microscopy.- Giemsa Staining.- The Usage of Banding Techniques.- Abnormalities Detected by Banding Analysis.- Chemical Properties of the Bands.- Technical Appendix.- 3 The Thalassemias: Models for Analysis of Quantitative Gene Control.- History.- Definition.- Organization of Globin Genes.- Ontogeny of Hemoglobin Production.- Inheritance of Thalassemia.- Frequency of Thalassemia.- Regulation of Hemoglobin Synthesis and Turnover.- Transcription of Hemoglobin Genes.- Intranuclear Processing of the Primary Gene Product.- Transport of Messenger RNA to the Cytoplasm.- Cytoplasmic Metabolism of Messenger RNA.- Balance of Hemin and Globin (Protein) Synthesis in Reticulocytes.- Other Steps in Hemoglobin Synthesis and Degradation.- Pathophysiology of the Thalassemias.- Directions in Therapy.- Note Added in Proof.- 4 Spontaneous Mutation in Man.- 'Classical' Mutation Rates.- Molecular Aspects of Human Mutation.- Spontaneous Mutation in Other Organisms and Its Significance for the Understanding of Human Mutations.- 5 Genetic Screening Legislation.- The Public Health Power.- Legislation Mandating Detection of Genetic Disease.- Legislation Mandating Screening for Genetic Traits.- Future of State-Supported Genetic Screening.
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Taschenbuch. Zustand: Neu. Neuware - Three articles make up Volume 10 of Methods in Membrane Biology. In the first of these, Papahadjopoulos, Poste, and Vail extensively review much of the available data on the fusion of natural membranes, model membranes (liposomes), and natural membranes with liposomes. The authors are led by…their review of the experimental methods and their interpretations of the results obtained to a general theory of membrane fusion which they believe is applicable to all systems that have been studied. Arguing that although protein and carbohydrate may serve, in some cases, to bring membranes into sufficiently close proximity for fusion to occur and, in other cases, to remove peripheral and integral proteins from the regions that are to undergo fusion, the authors conclude that membrane fusion per se is solely a property of the lipid bilayer. In their view, all the experimental observations to date can be subsumed under a unifying hypothesis in which membrane fusion is the result of a phase separation in one-half of the membrane bilayer brought about by the interaction - of calcium ions with acidic phospholipids, mostly phosphatidylserine. Where half-membranes already contain sufficient acidic phospholipids, a local increase in calcium ion concentration may suffice to induce fusion (examples might include exocytosis and fusion of intracellular membrane systems). In other cases, natural or experimentally induced events preceding fusion might be necessary to increase the local concentration of the acidic phospholipids in the half-membrane (virus-or fusogenic agent-induced cell-to-cell fusion, or endocytosis, for example).
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Taschenbuch. Zustand: Neu. Neuware - This is the third volume in the series of books based on the Annual Merseyside Course in Clinical Psychology. In common with its predecessors its aim is to present a number of topics of interest to practitioners, researchers, trainers and trainees in the field, with the intent not only to inf…orm but variously also to question and to guide further enquiry. Selection for this volume has taken a somewhat different stance to the previous two. Whereas in former volumes an attempt has been made to cover standard areas of general and scientific interest to psychologists and others in related professions, such as anorexia nervosa, forensic issues, long term care, mental handicap, community psychology, anxiety and de pression, in this one issues which are of equal relevance but not necessarily of equal prominence in psychological texts, are included. We have not, however, neglected those areas more readily recognized as of major clinical import which are being progressively covered in this series. This year we have the section 'Bereavement and the Care of the Dying'. Although for many this may not be a main focus, it is a subject that few helpers do not encounter either directly or indirectly with their clients. It would be impossible for this subject to not reflect the most human side of the caring professions, and it is perhaps in this field that the objective/subjective dilemma of the clinician can be seen in its most acute form.
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Taschenbuch. Zustand: Neu. Neuware - Volume 9 of Developments in Applied Spectroscopy pr e sents a collection of tventy-three selected papers presented during the 21st Mid-America Symposium on Spectroscopy, held in Chicago, June 2-5, 1970, In general. these papers are those of the symposium type and not papers pertaining to a sp…ecific research topic that one voul~ expect to find in the journals. The 21st Mid-America Symposium vas sponsored by the Chicago Section in cooperation vith Cincinnati, Cleveland, Indiana, Nev England, Nev York, Niagara Frontier and Ohio Vall ey Sections of the Society of Applied Spectroscopy, and the Chicago Gas Chromatography Group. Although the Mid America is stiIl occasionally thought of as a regional meet ing, its attendees and authors come from all parts of the United States and Canada as vell as other countries outside North America. Both theoretieal and applied principles vere presented in sessions on emission, molecular and atomic absorption, x-ray, mass, nuclear, electron, and nuclear magnetic and electron spin resonanee spectroscopy; air and Water pOllution analyses; biomedical technology; polymers and elastomeric materials; and computer applications. The chairmen of the Symposium Committees, Mr. E. Baclavski. Dr. W. K. Baer, Mr. J. E. Burroughs, Dr. C. R. Brundle, Mr. C. Hastings, Mr. J. B. Himes, Mr. R. Isaac, Dr. R. J. Jakobsen, Mr. J. Kinder, Dr. J. L. Koenig, Mr. W. A. Loseke, Dr. R. Mattoon, Miss V. McMahon, Dr. C.E. Moore, Mr. C. S. Naiman, Dr. M. J. Oestmann, Mr. C. R.
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Taschenbuch. Zustand: Neu. Neuware - The Laser Raman Workshop on the r'eas urement of Gas Properti es i sone of aseries of occasional meetings organized in an informal workshop format through the stimulation of Project SQUID, Office of Naval Research. This workshop is the second to be organized on gas-phase applications of Raman… scattering. Both Raman workshops were supported by Project SQUID, ONR, and the Air Force Aero Propulsion Laboratory, Wright-Patterson Air Force Base. The first Raman Workshop was held at the AVCO Everett Research Laboratory, Everett, Massachusetts, with their co-sponsorship in January 1972 under the chairmanship of D. A. Leonard. The present meeting was co-sponsored by the General Electric Research and Development Center, and held at their facility in Schenectady, New York. We are grateful to Project SQUID, AFAPL, and GE for their generous financial support of this Workshop, and to Project SQUID for underwriting the publication costs of the Proceedings. As is always the case for successful meetings, many people contributed substantially to the organization and execution of this workshop. Professor Robert Goulard supported, aided, and encouraged us in the most helpful ways, and we are indebted to him. We received further valuable support and assistance from Dr. Ralph Roberts, Director, and Mr. James R. Patton, Jr., of the Power Branch, Office of Naval Research; from Dr. William H. Heiser, Chief Scientist of the Aero Propulsion Laboratory; and from Dr. James M.
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Taschenbuch. Zustand: Neu. Neuware - This is not a textbook nor an encyclopedia; rather, it is a collection of papers representing a variety of points of view on contemporary is sues, controversies, and questions about female sexual development. The editor has a point of view, not a point of view as to which of the various autho…rs' positions presented in this book is correct, or even the most useful, but a point of view about the format of such a book; namely, that the definitive answers, and the experts who will provide them, are not yet identified. Therefore, many voices should be heard from different areas of expertise, training, experience, and back ground. Inevitably there are contradictions and disagreements. There should be. Several authors who were asked to provide short discus sions for papers found themselves unable to answer in less than an ad ditional paper. The editor welcomed this response. This is an area full of ancient myths, new discoveries, and alternate perspectives. It is hoped that the book reflects these ambiguities and controversies and that it will stimulate as many questions as it provides answers. You will find represented in this volume, and its forthcoming companion volume on women's sexual experience, authors not gener ally found together between the covers. When useful and where pos sible, a discussion or an addendum to a paper has been included by an author who approaches the subject from a different base of infor mation or experience.
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Taschenbuch. Zustand: Neu. Neuware - We are pleased to present Volume 9 of our highly successful series, which now celebrates 12 years of providing the magnetic resonance community with topical, authoritative chapters on new aspects of biological magnetic resonance. As always, we try to present a diversity of topic coverage in e…ach volume, ranging from applications of in vivo magnetic resonance to more fundamental aspects of electron spin resonance and nuclear magnetic resonance. Philip Yeagle presents an eagerly awaited chapter on 31p NMR studies of membranes and membrane protein interactions. Alan Marshall has con tributed two chapters to the volume: one, with Jiejun Wu, describes magnetic resonance studies of 5S-RNA as probes of its structure and conformation; the secon.
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Taschenbuch. Zustand: Neu. Neuware - Volume 4 of Advances in Nutritional Research reflects the increased importance that recently has been attached to nutrition in many fields of clinical medicine. This heightened interest in nutrition stems from the demonstration that the intake of specific nutrients may have far-reaching conse…quences, not only for normal metabolism, but also for metabolic processes affecting clinical or subclinical disease. Conversely, many disease states have been shown to have previously unrecognized effects on nutrient function and metabolism. In addition to topics of obvious relevance to human clinical nutrition, this volume contains chapters dealing with the nutrition of cells grown in culture and of species that may provide insights into nutritional disorders of man. To gether with its predecessors, Volume 4 provides graduate students and estab lished investigators with authoritative accounts of the status of research on a range of topics of current interest in experimental and clinical nutrition. vii Contents Chapter 1. Vitamin-Responsive Genetic Abnormalities . . S. Harvey Mudd 1. Introduction. 1 2. Historical Perspective . 2 3. Genetic Abnormalities Currently Known to Be Vitamin Responsive. 3 4. Mechanisms Underlying Vitamin Responsiveness. . . . . . . . . . . . . . . . 7 4.1. Defects in the Processing of a Vitamin Prior to Its Interaction in Cofactor Form with a Particular Apoenzyme . 7 4.2. Defects in Particular Apoenzymes that Interact with the Cofactor Forms of Vitamins. . . . . . . . . . . . . . . . . . 16 . . . . . .
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Taschenbuch. Zustand: Neu. Neuware - Volume 5 of this series continues its coverage of currently active re search fields in ornithology. Because an editor can never be a disin terested observer of his or her own editorial efforts, any claim for su periority of this volume is not without conflict of interest. Even so, Volume 5 ha…s certain merits that even a parent should acknowledge, and I find the current chapters not merely timely and authoritative but compelling in their demand for a reader's attention. Wolfgang and Roswitha Wiltschko provide a perceptive review of magnetic orientation in birds, a piece dedicated to Fritz Merkel, the pioneer in studies of magnetic orientation. Sergei Kharitonov and Doug las Siegel-Causey are concerned with the behavioral ecology of seabird coloniality, emphasizing their field experiences in the USSR and the United States. Ted Miller examines the application of studies of bird behavior to comparative biology, pursuing the interface of behavior and evolutionary biology adumbrated by Konrad Lorenz in the 1930s. Jeremy Raynor gives us a summary of the work over the past decade on bird flight, which is not, by turns, as complex or as simple as we had formerly believed. Carrol Henderson describes recent develop ments in nongame bird conservation, based on his pioneering work in the State of Minnesota. Alan Kamil discusses optimal experimental design for research in ornithology, a field in which experimental work is frequently difficult to pursue.
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Taschenbuch. Zustand: Neu. Neuware - Identified Neurons and Behavior of Arthropods presents for the larger audience the papers delivered at a symposium of the same title. I organized this symposium so that a few of the many who owe him a great scientific debt could honor Professor C. A. G. (Kees) Wiersma upon his attaining the a…ge of 70 and retiring from the California Institute of Technology. Everyone of the participants publicly acknowledged his debt to Kees Wiersma, but in a sense there was no need to do so, because the research reported spoke for itself. Seldom in a rapidly developing branch of modem science has all of the recent progress so clearly stemmed from the pioneering work of a single figure. But in this subject, the role of identified nerve cells in determining behavior, Wiersma stood virtually alone for 30 years. He it was who first showed that indi vidual nerve cells are recognizable and functionally important and have 'per sonalities' of their own.
Sprache: Englisch
Verlag: Springer Us Dez 2012, 2012
Serie: Advances in Experimental Medicine and Biology, Buch 5 von 544. Buch 5 von 544 - Advances in Experimental Medicine and Biology
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Taschenbuch. Zustand: Neu. Neuware - The ontogeny of lymphoid cells seems the most appropriate place to start. The early events in T and B cell ontogeny are still confusing. There seems to be no agreement on the data and on the semantics of the question of progenitor vs. stem cells. Nevertheless, we are beginning to understand m…ore about progenitor cells which are committed to particular cell lines, and about stem cells in the sense of having almost unlimited capability of giving rise to undifferentiated progeny. An important future development will be to determine the nature of the substances that attract stem cells and which are produced by specialized thymus epithelium, and perhaps by the bursa. The way stem cells recognize these signals is an important question to answer. Not predictable from mammalian models has been the observation that there is a lack of cells called into the bursa even before the signal for entry of stem cells has been shut off. A likely model suggested that after a certain point in development there were no longer any cells capable of migrating into the bursa and becoming B cells. A fascinating possibility is the suggestion that a cell comes into the bursa, is not committed, then can still wander into the thymus. This cell does not appear to have B cell characteris tics; that is, immunoglobulin is not expressed on its surface.
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Taschenbuch. Zustand: Neu. Neuware - We are pleased to present to our readers the proceedings of th~ Third Bari Seminars in Nephrology. The tDpic ~f these proceedi~gs deals with effects of drugs and o.yst el'll C ct i se;'Isc;- an the Id dney. Tho B rj S~~jnar5 in Nephr~logy are bi-annual meetings ~tt~~~Dd k) D large internation…al audience comprised of clinicians-scientist~ in the various displines of ~~phrnlDgy nnrl rQlated fi~ld$. The ne~t Bari S~mjnar5 of Nephrology will take place i' npril 19qn ~nd thp theme of the gathering will be Interstitial Nephritidies and Obstructive Uropathy. We are indc-bted for the goner-ells financial support of the Centro N::I~innalC' ti Pds. :'ll Pds. '', Pichp.rche, Italy. Alberto Amerio Pasquale Coratelli Vito M. Campese Shaul G. Massry vii CONTENTS Lupus Nephritis: Pathogenesis, Course and Management . . . 3 James E. Balow Prognostic Determinants in Lupus Nephritis . . 17 P. Coratelli, R. Rizzi, G. Pannarale, A. Ramunni M. Giannattasio, and G. Passavanti Thrombotic Microangiopathy in Lupus Nephritis . . . 35 . M.T. Porri, M.I. Quarenghi, F. Ferrario G. Colasanti, R. Rossi, E. Schiaffino, G. Toia, and G. D'Amico Vasculitis and the Kidney . . . . . . . . . . 41 .
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Taschenbuch. Zustand: Neu. Neuware - This volume contains most of the papers presented at the First International Symposium on The Effect of Prolonged Drug Usage on Fetal Development held at the Beit-Berl Convention Center, Kfar Saba, Israel, on September 14 - 17, 1971. In order to obtain an overview of the effect of drugs on fe…tal development, it appeared desirable to gather the opinions of noted investigators regarding the goals already achieved and the future potential of prevention of fetal disorders due to drugs. More than one hundred and sixty scientists from fifteen countries participated, and over forty presented data which were collected in extensive laboratory, clinical and field studies. This small, comparatively informal, International Symposium was held in a relaxed environment and provided a suitable forum for scientists in many differing lines of research to evaluate together the recent advances in the role of drugs as teratogenic agents and methods for the rapid uncovering of the teratogenic potential of drugs to mankind.
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Taschenbuch. Zustand: Neu. Neuware - Since the appearance of the first two volumes of Modern Fluorescence Spectroscopy in 1976, important advances continue to be made in both the techniques and applications of molecular luminescence. In terms of 'hardware,' it is only recently that the application of laser excitation to molecula…r fluorometry has become feasible under conditions that are analy tically realistic. The improvements that can be effected in sensitivity, analy tical selectivity, and ability to handle 'difficult' samples by laser fluorometry have only begun to be exploited. Likewise, time-resolved fluorometry has received widespread use in fundamental studies (a sizable number of which deal with biological systems), but has as of yet received relatively little analytical utilization. The use of electronic array detectors offers the promise of obtaining luminescence spectra more rapidly, and perhaps ultimately with greater sensitivity, than is possible by the use of scanning instruments equipped with conventional detectors. The increasing capabilities of microcomputers and the increasing sophistication of 'smart' spectroscopic instrumentation signify that much more efficient acquisition and use can now be achieved of the information contained in the 'excitation-emission matrix' inherent in the luminescence phenomenon.
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Taschenbuch. Zustand: Neu. Neuware - The application of the Fourier transform is being seen to an increasing extent in all branches of chemistry, but it is in the area of chemical analysis that the greatest activity is taking place. Fourier transform infrared and nuclear magnetic resonance spectrometry are already routine method…s for obtaining high-sensitivity IR and NMR spectra. Analogous methods are now being developed for mass spectrometry (Fourier transform ion cyclo tron resonance spectrometry) and microwave spectroscopy, and Fourier transform techniques have been successfully applied in several areas of electrochemistry. In addition the fast Fourier transform algorithm has been used for smoothing, interpolation, and more efficient storage of data, and has been studied as a potential method for more efficient identification of samples using pattern recognition techniques. Linear transforms have also been shown to be useful in analytical chemistry. Probably the most important of these is the Hadamard transform, which has been applied in alternative methods for obtaining IR and NMR data at high sensitivity. Even though measurements involving this algorithm will probably not be applied as universally as their Fourier transform ana logs, in the area of pattern recognition application of the Hadamard trans form will in all probability prove more important than application of the Fourier transform.
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Taschenbuch. Zustand: Neu. Neuware - This book includes the proceedings of a NATO Advanced Study Institute held at Washington State University, Pullman, Washington from July 26 until August 6, 1982. Although genetic engineering in eukaryotes is best developed in yeast and mammalian cells, the reader will find that some emphasis…has been put on plant systems. Indeed, it was our position that the development of plant cell genetic transformation would benefit from the interactions between a comparatively smaller number of fungal and animal cell experts and a larger number of plant cell specialists representing various aspects of plant molecular genetic research. On the other hand, it is clear that the ultimate achievements of plant genetic engineering will have a tremendous ~pact on, among other things, food production without generating the problems of ethics encountered when one contempla-tes the genetic modification of human beings. Therefore, this slight bias in favor of the plant kingdom simply reflects our belief that a 'second green revolution' will benefit mankind to a greater extent than any other kind of genetic engine ering. The keynote lecture of the Institute was delivered by Dr. John Slaughter, Director of the National Science Foundation, whom we deeply thank for his words of encouragement and commitment to the genetic manipulation of plants.
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Taschenbuch. Zustand: Neu. Neuware - Each of the four authors of this book has a particular interest in disorders of porphyrin metabolism and special experience in their management. Their individual involvement in the field varies from 12 to 52 years and, combined, represents more than a century of personal experience. Since it…has been written by both basic scientists and practicing physicians, the book is intended to be of value to all those involved in porphyrin metab olism and the porphyrias. It is hoped that the fascination of porphyrin metabolism and the clinical challenge of the porphyrias experienced by each of the authors will be conveyed to the readers. Michael R. Moore Kenneth E. L. McColl Claude Rimington Abraham Goldberg vii CONTENTS Color Plates . xvii 1. The History, Classification, and Incidence of the Porphyrias 1 1.1. History . 1 1.1.1. Early Chemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.1.2. Early Descriptions of Porphyria . 4 1.1.3. Biochemical Developments . 4 1.1.4. Acute Porphyria . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 1.1.5. A Complete Pathway . 8 1.2. Classification of the Porphyrias . . . . . . . . . . . . . . . . . . . . . 9 1.2.1. The Current Classification. . . . . . . . . . . . . . . 12 . . . .
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Taschenbuch. Zustand: Neu. Neuware - A satellite symposium entitled 'Myelination and Demyelination: Recent Chemical Advances' was held in Helsinki from August 29 to 31, 1977, after the Sixth International Meeting of the International Society for Neurochemistry (ISN) in Copenhagen. Myelin is a nervous tissue structure that is mos…t suitable as a subject of biochemical investigation. It is easy to isolate in a highly purified form, is rather stable even after death, and is af fected by a variety of neurological and other diseases. Its lesions are particularly important in the study of multiple sclerosis, a disease which is relatively prevalent in Finland and has therefore been of interest to a great many Finnish scientists. The first half of this book is concerned with the biochemical composition and molecular organization of myelin, the second half with the experimental and clinical aspects of demyelination. The comments given after each of the presentations at the symposium were not recorded as such, but each author was requested to modify his or her paper accordingly. The editing and publication of this book would not have been possible without the excellent efforts and co-operation of my wife, Mrs. L.-M. Palo, acting as general secretary and later as editorial secretary of the symposium. As Organizing Committee Chairman, I would also like to thank the members of the Committee: Dr. M. Haltia, Dr. E. Kivalo, Dr. T. Kosunen, Dr. M. Panelius, and especially Dr.
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Taschenbuch. Zustand: Neu. Neuware - We are pleased to present to our readers the Proceedings of the Sixth International Workshop on Phosphate and Other Minerals which was held in Verona, Italy, during June 24-26, 1983. It was hosted by Professor Giuseppe Maschio, Professor of Medicine and Chief, Department of Nephrology at the…University of Verona. The Sixth Workshop maintained the tradition of the previous ones. It provided a unique and outstanding opportunity for close interaction between scientist involved in the research of the overall field of Mineral Metabolism. The current Workshop was attended by 250 scientists from 15 countries including Austria, Canada, Denmark, England, France, Germany,Holland, Israel, Italy, Japan, Spain, Sweden,Switzerland, and the United States of America. The topics discussed included the renal handling of phosphate, transport of other minerals, intestinal absorption of calcium and phosphate and phosphate homeostasis in health and disease. Two symposia dealing with the recent developments of the interactions between minerals, parathyroid hormone, and blood pressure and between minerals and myopathies were included. In addition to the 15 State-of-the-Art Lectures, there were 43 oral and 63 poster presentations selected from over 200 abstracts sub mitted to the Program Committee. The Seventh International Workshop on Phosphate and Other Minerals will be held during September, 1985, in Marseille, France. It will be hosted by Professor Michel almer, Chief of the Department of Nephrology at the University of Marseille. The theme of this coming Workshop will focus on the pathophysiology of phosphate homeostasis and the metabolism of other minerals.
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Taschenbuch. Zustand: Neu. Neuware - The International Workshop on human lactation dedicated specifically to the topic of Maternal and Environmental Effects on Lactation repre sents the recent progress of research in human lactation. Only four years ago it was clear that we do not yet have sensitive research techniques specifica…lly adapted to the study of human milk. This need was addressed by an NIH convened workshop in 1982, the concensus being that appropriate methods have to be developed for the study of the composition of human milk. The progress in the development of these techniques was the subject of the second workshop on human lactation, dedicated specifically to 'Milk Components and Methodologies. ' The workshop was held in Colorado in 1984 and resulted in the publication of the first volume in the series of 'Human Lactation. ' At the Colorado meeting it was readily apparent that considerable progress has been made in the development of sensitive techniques able to quantitate the bioactive components of human milk (enzymes, growth factors, immuno-protective agents) as well as the macro, micro and trace elements. At the Colorado workshop it became clear that these workshops greatly benefit the research of human lactation by enhancing communication and collaboration among the investigators in the field. As a result it was decided to have a future workshop about a year later on the topic of 'Maternal-Environmental Effects on Human Lacta tion', and I was charged with chairing it.
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Taschenbuch. Zustand: Neu. Neuware - Many modern geneticists attempt to elucidate the molecular basis of phenotype by utilizing a battery of techniques derived from physical chemistry on subcellular components isolated from various species of organisms. Volume 5 of the Handbook of Genetics provides explanations of the advantages… and shortcomings of some of these revolutionary tech niques, and the nonspecialist is alerted to key research papers, reviews, and reference works. Much of the text deals with the structure and func tioning of the molecules bearing genetic information which reside in the nucleus and with the processing of this information by the ribosomes resid ing in the cytoplasm of eukaryotic cells. The mitochondria, which also live in the cytoplasm of the cells of all eukaryotes, now appear to be separate little creatures. These, as Lynn Margulis pointed out in Volume 1, are the colonial posterity of migrant prokaryotes, probably primitive bacteria that swam into the ancestral precursors of all eukaryotic cells and remained as symbionts. They have maintained themselves and their ways ever since, replicating their own DNA and transcribing an RNA quite different from that of their hosts. In a similar manner, the chloroplasts in all plants are self-replicating organelles presumably derived from the blue-green algae, with their own nucleic acids and ribosomes. Four chapters are devoted to the nucleic acids and the ribosomal components of both classes of these semi-independent lodgers. Finally, data from various sources on genetic variants of enzymes are tabulated for ready reference, and an evaluation of this information is attempted.
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Taschenbuch. Zustand: Neu. Neuware - This is the fourth volume of Ultrasound in Medicine, the Proceedings of the Annual Scientific Meeting of the American Institute of Ultrasound in Medicine. Unless the Executive Board of the Institute change their mind, it may also be the last. Under these circumstances it is somewhat ironical…that some of the deficiencies present in previous volumes appear to have been solved in the present volume. Notably, the Programme Committee, for the first time, exercised a stringent selection procedure by means of which the number of papers selected for presentation was limited with the result that both the quality of papers accepted for presentation and publication was improved and the number of simultaneous sessions at the meeting did not exceed two. The contents of this volume have been divided into the same sections as in previous volumes except that no papers on stan dardization procedures were accepted and a new supplementary section is added consisting of papers given at the Scientific Meeting of the American Society of Ultrasound Technical Specia lists. As in previous editions the readers may consider the engin eering sections at the end of this volume are the most rewarding. Some ingenious new systems are described both in the sections on Doppler techniques and new techniques. Current interest in tissue signatures and characterization are reflected in many of the pap~rs appearing in the Tissue Interactions section.
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Taschenbuch. Zustand: Neu. Neuware - The study of bacterial plasmids has not always been as popular as it is today. For many years, the molecular biology of pro cary otes was focused heavily on bacteriophage and plasmid investigations which were carried out in only a few laboratories. Whatever inter est existed in plasmids conce…rned the role of these extrachromosomal elements in bacterial conjugation, genetic exchanges, and antibiotic resistance, as well as in the structure of plasmids themselves. Gradually, however, it became increasingly evident that many of the special characteristics displayed by bacteria of medical, agricul tural, industrial, and environmental importance are determined by genes carried by plasmids, and this interest in plasmid-encoded functions, such as bacterial virulence properties (exotoxin produc tion, serum resistance, adhesiveness), metabolism of organic com pounds, plant tumor formation, and biological nitrogen fixation, led to increasing study of. the plasmids that carry these genes. Inves tigations of other plasmid-related properties such as replication and recombination have yielded much information about fundamental biological processes; information having implications that extend far beyond the particular plasmids under study. Concurrently, plas mids were playing a key role in the discovery of bacterial transpos able elements and were proving to be increasingly useful in the elu cidation of mechanisms responsible for a variety of chromosomal rearrangement events in bacteria and plants. Their status as 'mini chromosomes' that could be isolated easily from bacterial cells and then reintroduced into other cells by transformation is of fundamen tal importance in this regard.
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Taschenbuch. Zustand: Neu. Neuware - In August 1979 a group of 94 physicists from 60 laboratories in 21 countries met in Erice to attend the 17th Course of the International School of Subnuclear Physics. The countries represented at the School were: Argentina, Australia, Austria, Belgium, Canada, Federal Republic of Germany, Fra…nce, Hungary, India, Italy, Japan, Korea, the Netherlands, Nor way, Poland, Rumania, Spain, Sweden, the United Kingdom, the United States of America, and Yugoslavia. The School was sponsored by the Italian Ministry of Public Education (MPI), the Italian Ministry of Scientific and Techno logical Research (MRST) , the Sicilian Regional Government, and the Weizman Institute of Science. In the theoretical sessions, as expected, Sidney Coleman's (liN) lectures provided a new masterpiece in his Erice series. Andre Martin lectured on the theory of new particles, R.L. Jaffe on the Bag Hodel and Francis E. Low on quark status at low energy. In the more specialized section we were able to reflect on the problem of asymptotic changes in gauge theory, troubles experienced with instantons and finally on the fate of false vacua, thanks to A. Patrascioiu, R. Petronzio, and H. Kleinert. A quite exceptional event this year was the special QCD session wId_ch I leave the reader to enjoy without further introduction.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Despite an enormous investment of effort throughout the world, cancer is still a major barrier to human longevity. Cancer deaths are estimated to be more than five million globally. Currently responsible for about 20% of all deaths in… developed coun tries, the burden of cancer is steadily increasing in the developing world, following the control of malnutrition and infectious and parasitic diseases. Deeply impressed by the report of the Symposium on Geographic Pathology and Demography of Cancer held at Oxford in 1950, and through his preliminary work on cancer mortality statistics in Japan, Professor M. Segi decided to devote his life to the fight against cancer by establishing worldwide comparative cancer statistics-one of the landmarks in cancer studies and in cancer prevention strategies. He and his associates published six volumes of Cancer Mortality in 24 Countries with reliable mortality statistics covering 1950-1967, using the world population which he had derived as a standard. These publications rapidly became standard works of reference on the subject throughout the world. Professor Segi was a pioneer of cancer epidemiology in Japan. He cleaved a path through the jungle of cancer using epidemiological methods. By promoting cancer studies, he overcame the poor understanding of malignant disease which existed after World War II, when cancer mortality rates were still low. 240 pp. Englisch.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We try in this book to provide a detailed but readable, technical but accessible monograph on energy in the United States. We treat energy as a multidisciplinary challenge and apply the standard tools of economists, physicists, engine…ers, policy analysts, and, some might claim, fortune tellers. We hope that it will be used in classrooms of various types, and read by the general reader as well. That increased energy efficiency should be the first priority of energy policymakers is a conclusion, not an assumption, of our analysis. Many analysts have arrived at this conclusion while working separately on energy supply problems. The magnitude and scope of supply problems, primarily problems of high prices and environmental costs, lead one inexorably back to reducing demand growth as the first, most important step in any plausible energy future. We examine, in some depth, why much of the past literature on energy still points, fallaciously in our opinion, to high energy c- v Preface vi sumption futures. This is in Part I (called 'A Short History of the Future'). We devote one-third of the book (Part II) to energy resources, their internal and external costs, and the quantities of energy to be derived from these resources. This analysis provides a context within which the economic and social value of energy conservation options can be assessed. 276 pp. Englisch.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The NATO Science Committee and its subsidiary Programme Panels provide support for Advanced Research Institutes (ARI) in various fields. The idea is to bring together scientists of a chosen field with the hope that they will achieve a… consensus on research direc tions for the future, and make recommendations for the benefit of a wider scientific community. Attendance is therefore limited to those whose experience and expertise make the conclusions significant and acceptable to the wider community. Participants are selected on the basis of substantial track records in research or in the synthesis of research results to serve mankind. The proposal for a one-week ARIon Earth Observation and In formation Systems was initiated by the NATO Special Programme Panel on Systems Science (SPPOSS). In approving the ARI, the senior NATO Science Committee identified the subject as one of universal impor tance, requiring a broad perspective on the development of opera tional systems based on successful experimental systems. The general purpose of this ARI was to address the critical problems of integrating the relatively new science and technology of remote sensing into operational earth observation and manage ment information systems. The main problems of concern were those related to systems design, organization, development of infrastruc ture, and use of information in decision processes. The main empha sis was on problems of transferring technologies and methods from experimental to operational systems. 492 pp. Englisch.
