springer us mai 1993 (30 Ergebnisse)

Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Bacterial plasmids originating in a wide range of genera are being studied from a variety of perspectives in hundreds of laboratories around the globe. These elements are well known for carrying 'special' genes that confer important survival properties, frequently neces sary under atypical conditions. Classic examples of plasmid-borne genes are those provid ing bacterial resistance to toxic substances such as antibiotics, metal ions, and bacte riophage. Often included are those determining bacteriocins, which may give the bacterium an advantage in a highly competitive environment. Genes offering metabolic alternatives to the cell under nutritionally stressed conditions are also commonly found on plasmids, as are determinants important to colonization and pathogenesis. It is likely that in many, if not most, cases plasmids and their passenger determinants represent DNA acquired recently by their bacterial hosts, and it is the characteristic mobility of these elements that enables their efficient establishment in new bacterial cells by the process known as conjugation. Whereas many plasmids are fully capable of promoting their own conjugal transfer, others move only with help from coresident elements. The ability of a plasmid to establish itself in a variety of different species is com mon, and recent studies have shown that transfer can in some cases occur from bacterial cells to eukaryotes such as yeast.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 432 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book presents a thorough description of the acoustics of the sounds used in American English. It presents the subject from the points of view of both linguistics and physics and is intended for students and professionals interested in acoustic phonetics, linguistics, physics, electrical engineering, and computer science.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 412 pp. Englisch.

Buch. Zustand: Neu. Neuware -Mathematics is playing an ever more important role in the physical and biological sciences, provoking a blurring of boundaries between scientific disciplines and a resurgence of interest in the modern as weil as the clas sical techniques of applied mathematics. This renewal of interest, bothin research and teaching, has led to the establishment of the series: Texts in Applied Mathematics (TAM). The development of new courses is a natural consequence of a high Ievel of excitement on the research frontier as newer techniques, such as numerical and symbolic computer systems, dynamical systems, and chaos, mix with and reinforce the traditional methods of applied mathematics. Thus, the purpose of this textbook series is to meet the current and future needs of these advances and encourage the teaching of new courses. TAM will publish textbooks suitable for use in advanced undergraduate and beginning graduate courses, and will complement the Applied Mathematical Seiences (AMS) series, whichwill focus on advanced textbooks and research Ievel monographs. Preface This book is based on a one-term coursein fluid mechanics originally taught in the Department of Mathematics of the U niversity of California, Berkeley, during the spring of 1978. The goal of the course was not to provide an exhaustive account of fluid mechanics, nor to assess the engineering value of various approximation procedures.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 192 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -To produce a comprehensive overview of macrophages and related cell types in a short review volume is an impossible task. When I selected the topics to be included, some equally important areas were omitted by necessity, and for this I apologize. My choices have been somewhat eclectic, touching subjects of personal interest (such as osteoclast biology and macrophage electrophysiology) or of current fashion (apopto sis, antigen processing, cell adhesion molecules). The book has also had to encompass areas of a more general flavor to provide balance for the general reader (such as reviews of macrophage development, heterogeneity, and function, and of the surface molecules expressed by macrophages). I thank all the authors for their prompt sub missions; all have been of high quality, and my editorial tasks, thankfully, have been minimal. Michael A. Horton London, United Kingdom ix Contents Chapter J An Overview of Receptors of MPS Cells lain Fraser and Siam on Gordon 1. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. The Mononuclear Phagocyte System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 3. Diversity of Macrophage Plasma Membrane Receptors. . . . . . . . . . . . . . . . 6 3. 1 A Structural Approach to Classification . . . . . . . . . . . . . . . . . . . . . . . . . . 6 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 3. 2 Multisubunit Receptors 3. 3 Soluble Receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 3. 4 Lectins and Lectin-Like Receptors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 4. Functions and Selected Examples. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 4. 1 Growth, Differentiation, and Modulation . . . . . . . . . . . . . . . . . . . . . . . . 14 4. 2 Cell-Cell and Cell-Matrix Interactions. . . . . . . . . . . . . . . . . . . . . . . . . . . 16 4. 3 Endocytosis and Scavenger Receptors. . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 4. 4 Secretory Responses and Biosynthesis of Effector Molecules . . . . . . 17 5. Concluding Remarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 6. References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 . . . . . . . . . . . . . . . . . . . .Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 460 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This text attempts to introduce the molecular biology of cell membranes to students and professionals of diverse backgrounds. Although several membrane biology books are available, they do not integrate recent knowledge gained using modern molecular tools with more traditional membrane topics. Molecular techniques, such as cDNA cloning and x-ray diffraction, have provided fresh insights into cell membrane structure and function. The great excitement today, which I attempt to convey in this book, is that molecular details are beginning to merge with physiological responses. In other words, we are beginning to understand precisely how membranes work. This textbook is appropriate for upper-level undergraduate or beginning graduate students. Readers should have previous or concurrent coursework in biochemistry; prior studies in elementary physiology would be helpful. I have found that the presentation of topics in this book is appropriate for students of biology, biochemistry, biophysics and physiology, chemistry, and medicine. This book will be useful in courses focusing on membranes and as a supplementary text in biochemistry courses. Professionals will also find this to be a useful resource book for their personal libraries.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 428 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -b Gene Expression . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 Joanne Chory, Lothar Altschmied, Hector Cabrera, Hsou-min Li, and Ronald Susek The Role of KNI in Plant Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 196 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Computer-Aided Design of Analog Circuits and Systems brings together in one place important contributions and state-of-the-art research results in the rapidly advancing area of computer-aided design of analog circuits and systems.This book serves as an excellent reference, providing insights into some of the most important issues in the field.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 116 pp. Englisch.

Buch. Zustand: Neu. Neuware - Due to the progress in VLSI technology, integrated circuit chips are now available that allow video/image signal processing to be performed with a single VLSI chip or small sets of VLSI chips. Recent standardization on bandwidth compression schemes for still images (JPEG) and motion pictures (H.261, R723, MPEG) also encourage the development of VLSI video/image processors for cost-effective solutions. Furthermore, recent trends suggest that the standardization on HDTB bandwidth compression for broadcasting and storage purposes is just around the corner. In terms of device technology, however, the progress achieved in increasing speed is not as high as that achieved by integration. The development of high speed systems is due to architectural effort, rather than device technology. This is why high speed architectures, such as those for special wired logic realization and for multi-processors are of great interest to VLSI system designers. VLSI Video/Image Signal Processing is an edited volume of original research comprising invited contributions by leading researchers.

Buch. Zustand: Neu. Neuware - The text Modern Electrochemistry (authored by J. O'M. Bockris and A. K. N. Reddy and published by Plenum Press in 1970) was written between 1967 and 1969. The concept for it arose in 1962 in the Energy Conversion Center at the University of Pennsylvania, and it was intended to act as a base for interdisciplinary students and mature scientists~hemists, physicists, biologists, metallurgists, and engineers-who wanted to know about electrochemical energy conversion and storage. In writing the book, the stress, therefore, was placed above all on lucidity in teaching physical electrochemistry from the beginning. Although this fundamentally undergraduate text continues to find purchasers 20 years after its birth, it has long been clear that a modernized edition should be written, and the plans to do so were the origin of the present book. However, if a new Bockris and Reddy was to be prepared and include the advances of the last 20 years, with the same degree of lucidity as characterized thefirst one, the depth of the development would have to be well short of that needed by professional electrochemists.

Taschenbuch. Zustand: Neu. Neuware -The text Modern Electrochemistry (authored by J. O'M. Bockris and A. K. N. Reddy and published by Plenum Press in 1970) was written between 1967 and 1969. The concept for it arose in 1962 in the Energy Conversion Center at the University of Pennsylvania, and it was intended to act as a base for interdisciplinary students and mature scientists~hemists, physicists, biologists, metallurgists, and engineers-who wanted to know about electrochemical energy conversion and storage. In writing the book, the stress, therefore, was placed above all on lucidity in teaching physical electrochemistry from the beginning. Although this fundamentally undergraduate text continues to find purchasers 20 years after its birth, it has long been clear that a modernized edition should be written, and the plans to do so were the origin of the present book. However, if a new Bockris and Reddy was to be prepared and include the advances of the last 20 years, with the same degree of lucidity as characterized thefirst one, the depth of the development would have to be well short of that needed by professional electrochemists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1080 pp. Englisch.

Buch. Zustand: Neu. Neuware -Instruction-Level Parallelism presents a collection of papers that attempts to capture the most significant work that took place during the 1980s in the area of instruction-level (ILP) parallel processing. The papers in this book discuss both compiler techniques and actual implementation experience on very long instruction word (VLIW) and superscalar architectures.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.

Buch. Zustand: Neu. Neuware -There are many different types of organisms in the world: they differ in size, physiology, appearance, and life history. The challenge for evolutionary biology is to explain how such diversity arises. The Evolution of Life Histories does this by showing that natural selection is the principal underlying force molding life history variation. The book describes in particular the ways in which variation can be analyzed and predicted. It covers both the genetic and optimization approaches to life history analysis and gives an overview of the general framework of life history theory and the mathematical tools by which predictions can be made and tested. Factors affecting the age schedule of birth and death and the costs of reproduction are discussed. The Evolution of Life Histories concentrates on those theoretical developments that have been tested experimentally. It will interest both students and professionals in evolution, evolutionary ecology, mathematical and theoretical biology, and zoology and entomology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 548 pp. Englisch.

Buch. Zustand: Neu. Neuware -In the area of computer-integrated manufacturing, concurrent engineering is recognized as the manufacturing philosophy for the next decade.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 512 pp. Englisch.

Buch. Zustand: Neu. Neuware -This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar keted or are under clinical testing. In previous volumes of this series,funda mental theories and principles ofprotein characterization and stability were presented in depth by researchers in their fieldsofexpertise. The way from theory to practice isnot alwaysobvious and straightforward. There isa need for practical examples of how the principles and theories are put into use, specificallyin the development of a pharmaceutical product. It is our hope that this volume will fulfillsuch a need. Itisnot asimple task to choose a panel ofproteinsand peptides from the over 200 agents in human clinical trials. We have tried to collect a wide representation of molecules of different sizes-from 10 amino acids (Leu prolide) to 1020 amino acids (Muromonab CD3). The examples include agents derived from various sources including monoclonal antibodies (Mur omonab CD3), recombinant DNA (human and bovine growth hormones), natural source (fibrolase), and chemical synthesis (Leuprolide). Clearly this list is not intended to be encyclopedic. It isthe first time a collection of this sort has been made accessibleto the formulation scientists involved in devel oping protein and peptide products. Although each chapter in this volume focuses primarily on the charac terization and stability of a specific molecule, each has unique aspects.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 380 pp. Englisch.

Buch. Zustand: Neu. Neuware -Leon N. Moses In June 1991, the Transportation Center at Northwestern University sponsored Hazmat Transport '91: A National Conference on the Transportation of Hazardous Materials and Wastes. The faculty associated with the center were aware that there had been many professional, industrial and government conferences and meetings on the subject. However, they believed that the unique capacity of the Transportation Center to bring together leaders from industry and government, as well as leading scholars from economics, law, engineering, psychology and sociology who have done research on the problems associated with the transportation of hazardous materials and wastes (hazmats), could produce a set of integrated insights and understandings that would go well beyond those of previous conferences. The papers that make up this volume were all delivered at Hazmat Transport '91. From a legislative point of view, they tend to deal with issues associated with the Hazardous Materials Transportation Act of 1975 (HMTA), the original act passed to regulate the transportation of hazardous materials, and the Hazardous Materials Transportation Uniform Safety Act of 1990 (HMTVSA). There were talks and papers presented at the conference that focused on other recent legislation and transportation issues with which HMTUSA does not deal. The conference proceedings volume also had discussions and papers on significant managerial and regulatory issues that could not be included in this volume because of constraints on its size. Therefore, this essay is made up of three parts.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 372 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -''Intended mainly for physicists and mathematicians.its high quality will definitely attract a wider audience.'' ---Computational Mathematics and Mathematical Physics This work acquaints the physicist with the mathematical principles of algebraic topology, group theory, and differential geometry, as applicable to research in field theory and the theory of condensed matter. Emphasis is placed on the topological structure of monopole and instanton solution to the Yang-Mills equations, the description of phases in superfluid 3He, and the topology of singular solutions in 3He and liquid crystals. 372 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Leon N. Moses In June 1991, the Transportation Center at Northwestern University sponsored Hazmat Transport '91: A National Conference on the Transportation of Hazardous Materials and Wastes. The faculty associated with the center were aware that there had been many professional, industrial and government conferences and meetings on the subject. However, they believed that the unique capacity of the Transportation Center to bring together leaders from industry and government, as well as leading scholars from economics, law, engineering, psychology and sociology who have done research on the problems associated with the transportation of hazardous materials and wastes (hazmats), could produce a set of integrated insights and understandings that would go well beyond those of previous conferences. The papers that make up this volume were all delivered at Hazmat Transport '91. From a legislative point of view, they tend to deal with issues associated with the Hazardous Materials Transportation Act of 1975 (HMTA), the original act passed to regulate the transportation of hazardous materials, and the Hazardous Materials Transportation Uniform Safety Act of 1990 (HMTVSA). There were talks and papers presented at the conference that focused on other recent legislation and transportation issues with which HMTUSA does not deal. The conference proceedings volume also had discussions and papers on significant managerial and regulatory issues that could not be included in this volume because of constraints on its size. Therefore, this essay is made up of three parts. 372 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -High-Performance CMOS Continuous-Time Filters is devoted to the design of CMOS continuous-time filters. CMOS is employed because the most complex integrated circuits have been realized with this technology for two decades. The most important advantages and drawbacks of continuous-time filters are clearly shown. The transfer function is one of the most important filter parameters but several others (like intermodulation distortion, power-supply rejection ratio, noise level and dynamic range) are fundamental in the design of high-performance systems. Special attention is paid to the practical aspects of the design, which shows the difference between an academic design and an industrial design. A clear understanding of the behavior of the circuits and techniques is preferred over complex equations or interpretation of simulated results. Step-by-step design procedures are very often used to clarify the use of the techniques and topologies. The organization of this text is hierarchical, starting with the design consideration of the basic building blocks and ending with the design of several high-performance continuous-time filters. Most of the circuits have been fabricated, theoretically analyzed and simulated, and silicon measurement results are compared with each other. High-Performance CMOS Continuous-Time Filters can be used as a text book for senior or graduate courses on this topic and can also be useful for industrial engineers as a reference book. 244 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Computer-Aided Design of Analog Circuits and Systems brings together in one place important contributions and state-of-the-art research results in the rapidly advancing area of computer-aided design of analog circuits and systems. This book serves as an excellent reference, providing insights into some of the most important issues in the field. 116 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is an exciting period in plant biology as many disciplines, such as genetics and biochemistry, are merging to provide a more detailed understanding of plant growth and development. The purpose of this meeting was to provide a sampling of some of this exciting work in the area of cellular communication and signal transduction. R. M. Amasino vii CONTENTS Auxin-Binding Proteins and their Possible Role in Cell Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Alan M. Jones Signal Perception in Plants: Hepta-B-Glucoside Elicitor Binding Proteins in Soybean . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Michael G. Hahn, Jong-Joo Cheong, Robert M. Alba, and Franfois Cote The Role of Salicylic Acid as a Plant Signal Molecule . . . . . . . . . . . . . . . . . . . . . . 15 Paul Silverman, Rebecca A. Linzer, and Ilya Raskin Blue-Light Regulated Gene Expression . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Lon S. Kaufman, Kathleen A. Marrs, Katherine M. F. Warpeha, Jie Gao, Keshab Bhattacharya, Judi TIlghman, and John F. Marsh III Role of the Maize Viviparous-l Gene in Regulation of Seed Maturation . . . . . . . . . 27 Donald R. McCarty Lovastatin Induces Cytokinin Dependence in Tobacco Cultures . . . . . . . . . . . . . . . . 37 Dring N. Crowell and Michael S. Salaz Molecular Genetic Approaches to Elucidating the Role of Hormones in Plant Development . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Harry Klee and Charles Romano Reversible Inhibition of Tomato Fruit Ripening by Antisense ACC Synthase RNA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Athanasios Theologis, Paul W. Oeller and Lu Min-Wong Genetic Dissection of Signal Transduction Pathways that Regulate cab Gene Expression . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 Joanne Chory, Lothar Altschmied, Hector Cabrera, Hsou-min Li, and Ronald Susek The Role of KNI in Plant Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196 pp. Englisch.

Taschenbuch. Zustand: Neu. Neuware -One of the liveliest areas of research in the social sciences is reading. Scholarly activity is currently proceeding along a number of different disciplinary lines, addressing a multitude of questions and issues about reading. A short list of disciplines involved in the study of reading would include linguistics, psychology, education, history, and gerontology. Among the important questions being ad dressed are some long-standing concerns: How are reading skills acquired What are the basic components of reading skill How do skilled readers differ from less skilled ones What are the best ways to approach instruction for different groups of readers-young beginning readers, poor readers with learning problems, and teenage and adult illiterates How can reading skill best be measured-what standardized instruments and observational techniques are most useful The large volume of textbooks and scholarly books that issue forth each year is clear evidence of the dynamic nature of the field. The purpose of this volume is to survey some of the best work going on in the field today and reflect what we know about reading as it unfolds across the life span. Reading is clearly an activity that spans each of our lives. Yet most accounts of it focus on some narrow period of development and fail to consider the range of questions that serious scholarship needs to address for us to have a richer under standing of reading. The book is divided into four parts.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text attempts to introduce the molecular biology of cell membranes to students and professionals of diverse backgrounds. Although several membrane biology books are available, they do not integrate recent knowledge gained using modern molecular tools with more traditional membrane topics. Molecular techniques, such as cDNA cloning and x-ray diffraction, have provided fresh insights into cell membrane structure and function. The great excitement today, which I attempt to convey in this book, is that molecular details are beginning to merge with physiological responses. In other words, we are beginning to understand precisely how membranes work. This textbook is appropriate for upper-level undergraduate or beginning graduate students. Readers should have previous or concurrent coursework in biochemistry; prior studies in elementary physiology would be helpful. I have found that the presentation of topics in this book is appropriate for students of biology, biochemistry, biophysics and physiology, chemistry, and medicine. This book will be useful in courses focusing on membranes and as a supplementary text in biochemistry courses. Professionals will also find this to be a useful resource book for their personal libraries. 428 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There are many different types of organisms in the world: they differ in size, physiology, appearance, and life history. The challenge for evolutionary biology is to explain how such diversity arises. The Evolution of Life Histories does this by showing that natural selection is the principal underlying force molding life history variation. The book describes in particular the ways in which variation can be analyzed and predicted. It covers both the genetic and optimization approaches to life history analysis and gives an overview of the general framework of life history theory and the mathematical tools by which predictions can be made and tested. Factors affecting the age schedule of birth and death and the costs of reproduction are discussed. The Evolution of Life Histories concentrates on those theoretical developments that have been tested experimentally. It will interest both students and professionals in evolution, evolutionary ecology, mathematical and theoretical biology, and zoology and entomology. 548 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Instruction-Level Parallelism presents a collection of papers that attempts to capture the most significant work that took place during the 1980s in the area of instruction-level (ILP) parallel processing. The papers in this book discuss both compiler techniques and actual implementation experience on very long instruction word (VLIW) and superscalar architectures. 288 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the area of computer-integrated manufacturing, concurrent engineering is recognized as the manufacturing philosophy for the next decade. 512 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar keted or are under clinical testing. In previous volumes of this series,funda mental theories and principles ofprotein characterization and stability were presented in depth by researchers in their fieldsofexpertise. The way from theory to practice isnot alwaysobvious and straightforward. There isa need for practical examples of how the principles and theories are put into use, specificallyin the development of a pharmaceutical product. It is our hope that this volume will fulfillsuch a need. Itisnot asimple task to choose a panel ofproteinsand peptides from the over 200 agents in human clinical trials. We have tried to collect a wide representation of molecules of different sizes-from 10 amino acids (Leu prolide) to 1020 amino acids (Muromonab CD3). The examples include agents derived from various sources including monoclonal antibodies (Mur omonab CD3), recombinant DNA (human and bovine growth hormones), natural source (fibrolase), and chemical synthesis (Leuprolide). Clearly this list is not intended to be encyclopedic. It isthe first time a collection of this sort has been made accessibleto the formulation scientists involved in devel oping protein and peptide products. Although each chapter in this volume focuses primarily on the charac terization and stability of a specific molecule, each has unique aspects. 380 pp. Englisch.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The text Modern Electrochemistry (authored by J. O'M. Bockris and A. K. N. Reddy and published by Plenum Press in 1970) was written between 1967 and 1969. The concept for it arose in 1962 in the Energy Conversion Center at the University of Pennsylvania, and it was intended to act as a base for interdisciplinary students and mature scientists~hemists, physicists, biologists, metallurgists, and engineers-who wanted to know about electrochemical energy conversion and storage. In writing the book, the stress, therefore, was placed above all on lucidity in teaching physical electrochemistry from the beginning. Although this fundamentally undergraduate text continues to find purchasers 20 years after its birth, it has long been clear that a modernized edition should be written, and the plans to do so were the origin of the present book. However, if a new Bockris and Reddy was to be prepared and include the advances of the last 20 years, with the same degree of lucidity as characterized thefirst one, the depth of the development would have to be well short of that needed by professional electrochemists. 1080 pp. Englisch.

Buch. Zustand: Neu. Neuware -High-Performance CMOS Continuous-Time Filters is devoted to the design of CMOS continuous-time filters. CMOS is employed because the most complex integrated circuits have been realized with this technology for two decades. The most important advantages and drawbacks of continuous-time filters are clearly shown. The transfer function is one of the most important filter parameters but several others (like intermodulation distortion, power-supply rejection ratio, noise level and dynamic range) are fundamental in the design of high-performance systems. Special attention is paid to the practical aspects of the design, which shows the difference between an academic design and an industrial design. A clear understanding of the behavior of the circuits and techniques is preferred over complex equations or interpretation of simulated results. Step-by-step design procedures are very often used to clarify the use of the techniques and topologies.The organization of this text is hierarchical, starting with the design consideration of the basic building blocks and ending with the design of several high-performance continuous-time filters. Most of the circuits have been fabricated, theoretically analyzed and simulated, and silicon measurement results are compared with each other.High-Performance CMOS Continuous-Time Filters can be used as a text book for senior or graduate courses on this topic and can also be useful for industrial engineers as a reference book.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

Buch. Zustand: Neu. Neuware -''Intended mainly for physicists and mathematicians.its high quality will definitely attract a wider audience.'' ---Computational Mathematics and Mathematical Physics This work acquaints the physicist with the mathematical principles of algebraic topology, group theory, and differential geometry, as applicable to research in field theory and the theory of condensed matter. Emphasis is placed on the topological structure of monopole and instanton solution to the Yang-Mills equations, the description of phases in superfluid 3He, and the topology of singular solutions in 3He and liquid crystals.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 376 pp. Englisch.

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -To produce a comprehensive overview of macrophages and related cell types in a short review volume is an impossible task. When I selected the topics to be included, some equally important areas were omitted by necessity, and for this I apologize. My choices have been somewhat eclectic, touching subjects of personal interest (such as osteoclast biology and macrophage electrophysiology) or of current fashion (apopto sis, antigen processing, cell adhesion molecules). The book has also had to encompass areas of a more general flavor to provide balance for the general reader (such as reviews of macrophage development, heterogeneity, and function, and of the surface molecules expressed by macrophages). I thank all the authors for their prompt sub missions; all have been of high quality, and my editorial tasks, thankfully, have been minimal. Michael A. Horton London, United Kingdom ix Contents Chapter J An Overview of Receptors of MPS Cells lain Fraser and Siam on Gordon 1. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. The Mononuclear Phagocyte System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 3. Diversity of Macrophage Plasma Membrane Receptors. . . . . . . . . . . . . . . . 6 3. 1 A Structural Approach to Classification . . . . . . . . . . . . . . . . . . . . . . . . . . 6 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 3. 2 Multisubunit Receptors 3. 3 Soluble Receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 3. 4 Lectins and Lectin-Like Receptors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 4. Functions and Selected Examples. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 4. 1 Growth, Differentiation, and Modulation . . . . . . . . . . . . . . . . . . . . . . . . 14 4. 2 Cell-Cell and Cell-Matrix Interactions. . . . . . . . . . . . . . . . . . . . . . . . . . . 16 4. 3 Endocytosis and Scavenger Receptors. . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 4. 4 Secretory Responses and Biosynthesis of Effector Molecules . . . . . . 17 5. Concluding Remarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 6. References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 . . . . . . . . . . . . . . . . . . . . 460 pp. Englisch.