Approaches to Gene Mapping in Complex Human Diseases

ISBN 10: 0471171956 / ISBN 13: 9780471171959

Verlag: Wiley & Sons, Incorporated, John, 1998

Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Bestandsnummer des Verkäufers 581157-6

Inhaltsangabe:

By emphasizing concepts and design rather than focusing on technical details, this book prepares the researcher to use all available resources intelligently and efficiently. Introductory chapter puts readers from diverse backgrounds on equal footing. Information about public databases, mapping resources and where to find theoretical information, software, and documentation are all presented.

Von der hinteren Coverseite: Approaches to Gene Mapping in Complex Human Diseases

Edited by Jonathan L. Haines and Margaret A. Pericak-Vance

Recent years have seen a tremendous growth in statistical and laboratory methods for genetic mapping -a process by which we discover genes that contribute to heart disease, hypertension, diabetes, asthma, cancer, and other complex genetic disorders not controlled by a single gene.

Approaches to Gene Mapping in Complex Human Diseases is the first book devoted to the analysis of such common, inherited diseases. This text helps the reader sort through the plethora of available resources, choose the best methodology for a given problem, and design successful gene mapping projects from the ground up. In eighteen chapters, compiled by two of the leading figures in the field, this book covers a wide range of topics -from the process of selecting families to the testing of candidate genes. It provides indispensable information on:
* Genetic concepts and statistics pertaining to mapping genetic disease
* Issues involved in collecting and handling biological samples and data
* Strategies for generating data in the lab
* Methods of analysis such as Lod score, Sib-pair, or Affected Relative-Pair
* Public databases and mapping resources
* Sources of statistical and genetic information, software, and documentation.

Approaches to Gene Mapping in Complex Human Diseases clearly explains concepts and design procedures while keeping technical details to a minimum. For geneticists, clinicians, molecular biologists, epidemiologists, and anyone interested in the pursuit of genes, it provides a solid grounding in the fundamentals and facilitates a firm grasp of the most advanced procedures and techniques available.

Bibliografische Details

Titel: Approaches to Gene Mapping in Complex Human ...
Verlag: Wiley & Sons, Incorporated, John
Erscheinungsdatum: 1998
Einband: Hardcover
Zustand: Very Good
Auflage: 1st Edition.