Beschreibung
Paris, 1907 ; 1 fascicule gr. in-8 (24.5 x 16 cm), 14 pp. ; broché, couverture verte imprimée, un peu défraîchie avec rousseurs et manque minime dans deux angles ; intérieur en très bon état. Tirage à part très rare de cette publication novatrice. Les auteurs montrent qu'à côté des ictères hémolytiques congénitaux, il existe des formes acquises, révélées à l'âge adulte, et qui diffèrent par un ensemble de caractères. Ils étudient les signes cliniques et hématologiques. En utilisant des hématies déplasmatisées, ils mettent en évidence une fragilité capillaire et notent l'existence d'hématies granuleuses ; ils estiment qu'il s'agit d'altérations communes aux ictères congénitaux, aux ictères acquis d'étiologies différentes et aux ictères expérimentaux. Ils notent aussi chez leurs trois malades une auto-agglutination "des plus nettes". Fernand Widal (1862-1929) et Pierre Léon Abrami (1879-1945) deviendront professeur de pathologie médicale à la Faculté de médecine de Paris ; Marcel Brulé (1883-1946) deviendra professeur agrégé de médecine. REFERENCES : Wintrobe MM: Blood, pure and eloquent, p. 232: "It was Widal, Abrami, and Brulé, and their collaborators, in a series of papers published from 1908 onwards who first established 'l'ictère hémolytique acquis' as a definitive entity."; Garrison & Morton, 3783 (citant le compte-rendu [d'une demi-page] de la communication préliminaire du 8 novembre 1907 à la Société Médicale des Hôpitaux de Paris paru dans la Presse Médicale du 16 novembre 1907 : Presse Med, 1907, 15, 749) : "Widal-Abrami disease (Hayem-Widal disease), acquired hemolytic anemia."; Jablonski S: Illustrated dictionary of eponymic syndromes and diseases, pp. 140, 327; Packman CH : The spherocytic haemolytic anemias, Br J Haematol, 2001, 112(4), 888-99: ?At about the same time as Chauffard reported his cases of congenital haemolytic icterus, his colleagues Widal et al (1907a, b, c, 1909) published a series of papers on a haemolytic icterus that was apparently neither congenital nor familial, that could appear gradually or suddenly during the course of various diseases or could be unassociated with any underlying disease. These cases were considered similar to those described by Hayem 10 years earlier. In contrast to Chauffard's patients, whom he described as more icteric than ill (icterique plutôt que vraiment malade), Widal's patients were severely anaemic and ill. They were all adults who lacked a family history or past history of icterus. The patients exhibited reticulocytosis, but the alterations in the fragility test were less marked than in the congenital form. Autoagglutination was observed in some of these patients."; Lichtman MA, Boxer LA & Spivak JL: Hematology: Landmark Papers of the Twentieth Century, p. 869: "In their paper, Boorman, Dodd, and Loutit [1945] commented on the insightful work of the French physician Widal, Abrami, and Brulé (1912), who from 1907 to 912 described cases of acquired hemolytic jaundice. They recognized an acquired form of hemolytic anemia in which autoagglutination was evident and stressed that it was a characteristic and defining finding. Controversy surround led these early reports, and, ironically, their descriptions were challenged and dismissed by prominent physicians in England. Subsequent sporadic reports lent credence to the occurrence of acquired acute hemolytic with autoagglutination (Greenwald, 1938). Boorman and colleagues, however, were the first to establish the concept of acquired immune hemolytic anemia using the newly available Coombs test."; Bernard J et al.: Histoire illustrée de l'hématologie, p. 229. Bestandsnummer des Verkäufers 1298-3
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