Histopathology of Preclinical Toxicity Studies: Interpretation and Relevance in Drug Safety Evaluation - Hardcover

Greaves, Peter

Hardcover

ISBN 10: 0444527710 ISBN 13: 9780444527714

Verlag: Elsevier Science Ltd, 2007

Über diesen Titel

Reseña del editor:

This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.

NEW TO THE THIRD EDITION:
* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies
* General comments to each chapter about the relevance of pathological findings to humans
* Provides essential information that can help decide the relevance of particular lesions for patients

Biografía del autor:

MBChB, FRCPath, Consulting Pathologist and Honorary Senior Lecturer, Department of Cancer Studies and Molecular Medicine, University of Leicester, UK

Über diese Auflage

• Verlag: Elsevier Science Ltd
• Erscheinungsdatum: 2007
• ISBN 10: 0444527710
• ISBN 13: 9780444527714
• Einband: Tapa dura
• Auflage: 3
• Anzahl der Seiten: 960