Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists - Softcover

Kwon, Younggil

Softcover

ISBN 10: 147578693X ISBN 13: 9781475786934

Verlag: Springer, 2013

Über diesen Titel

Reseña del editor:

In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization. During discovery phases, the identifi- tion of the critical PK/PD/DM issues of new compounds plays an essential role in understanding their pharmacological profiles and structure-activity relationships. Owing to recent progress in analytical chemistry, a large number of compounds can be screened for their PK/PD/DM properties within a relatively short period of time. During development phases as well, the toxicology and clinical study designs and trials of a compound should be based on a thorough understanding of its PK/PD/DM properties. During my time as an industrial scientist, I realized that a reference work designed for practical industrial applications of PK/PD/DM could be a very valuable tool for researchers not only in the pharmacokinetics and drug metabolism departments, but also for other discovery and development groups in pharmaceutical companies. This book is designed specifically for industrial scientists, laboratory assistants, and managers who are involved in PK/PD/DM-related areas. It consists of thirteen chapters, each of which deals with a particular PK/PD/DM issue and its industrial applications. Chapters 3 and 12 in particular address recent topics on higher throughput in vivo exposure screening and the prediction of pharmacokinetics in humans, respectively. Chapter 8 covers essential information on drug metabolism for industrial scientists.

Reseña del editor:

This volume is a handbook primarily designed for scientists andtechnicians without formal pharmacokinetics/pharmacodynamics (PK/PD)training, who work in an industrial setting. The book is a primarydesktop reference and contains easy-to-understand guidance for PK/PDissues, study design, and data interpretation. PK/PD are integralaspects for investigating the disposition and pharmacological efficacyof drugs under various experimental and clinical conditions.

Über diese Auflage

• Verlag: Springer
• Erscheinungsdatum: 2013
• ISBN 10: 147578693X
• ISBN 13: 9781475786934
• Einband: Tapa blanda
• Anzahl der Seiten: 316