Sex and Gender Differences in Cardiovascular-Renal Diseases and Hypertension (Colloquium Series on Integrated Systems Physiology: From Molecule to Function) - Softcover

Reckelhoff, Jane

Softcover

ISBN 10: 1615045783 ISBN 13: 9781615045785

Verlag: Morgan & Claypool Life Sciences, 2014

Inhaltsangabe

Páginas:98Géneros:12:MFG:PhysiologySinopsis:Manyofthemechanismsresponsibleforcardiovasculardiseaseandhypertensionarewellknown,andgenderisanindependentriskfactorinmanycohorts.Howgendercontributestocardiovasculardiseasehasnotbeencompletelyelucidated.Eveninnormotensivepopulations,bloodpressureishigherinmenthanwomen,althoughwhythisoccursisunclear.Whilebothmenandwomensufferfromhighincidencesofcardiovasculardisease,womenaretypicallyprotectedagainstcardiovasculardiseaseuntilaftermenopause,sothatonaveragetheyareabout10yearsolderthanmenwhenthesediseasesdevelop,makingagingaconfoundingproblemcontributingtoincreasedmorbidity.Becausehypertensionisoneoftheleadingcausesofcardiovasculardiseaseinbothmenandwomen,thisreviewwillfocusonhypertension,andthemechanismsthathavebeenfoundtoplayaroleinmediatingbloodpressurecontrolandhowtheydifferinmenandwomen._,

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Reseña del editor:

Many of the mechanisms responsible for cardiovascular disease and hypertension are well known, and gender is an independent risk factor in many cohorts. How gender contributes to cardiovascular disease has not been completely elucidated. Even in normotensive populations, blood pressure is higher in men than women, although why this occurs is unclear. While both men and women suffer from high incidences of cardiovascular disease, women are typically protected against cardiovascular disease until after menopause, so that on average they are about 10 years older than men when these diseases develop, making aging a confounding problem contributing to increased morbidity. Because hypertension is one of the leading causes of cardiovascular disease in both men and women, this review will focus on hypertension, and the mechanisms that have been found to play a role in mediating blood pressure control and how they differ in men and women.

Table of Contents: Overview and Epidemiology / Genetic and Non-Genetic Models of Hypertension / Hypertension and Sympathetic Nervous System Activation / Renin Angiotensin System / Oxidative Stress / Endothelin / Aging and Hypertension / Developmental Programming of Cardiovascular Disease / T Cells and Hypertension / Genetics / Sex Steroids and Receptors / Summary / References / Author Biography

Biografía del autor:

University of Mississippi Medical Center, Jackson, Mississippi

Über diese Auflage

• Verlag: Morgan & Claypool Life Sciences
• Erscheinungsdatum: 2014
• ISBN 10: 1615045783
• ISBN 13: 9781615045785
• Einband: Tapa blanda
• Anzahl der Seiten: 98