Protein Lipidation Protocols (Methods in Molecular Biology, 116, Band 116) - Hardcover

 
9780896035348: Protein Lipidation Protocols (Methods in Molecular Biology, 116, Band 116)
Hardcover
ISBN 10: 0896035344 ISBN 13: 9780896035348
Verlag: Humana, 1999

Inhaltsangabe

In Protein Lipidation Protocols, Michael Gelb brings together a collection of readily reproducible techniques for studying protein lipidation, the covalent attachment of lipids to proteins. These cutting-edge methods-many never published before in a "hands-on" format-deal with glycosyl phosphatidylinositol (GPI)-containing compounds, protein fatty acylation, and protein prenylation. Included are novel techniques for determining the chemical structure of GPI-anchors, for radiolabeling the prenyl groups of protein in eukaryotic cells, a tool for developing inhibitors of the protein farnesyltransferase, and for an exciting lysosomal enzyme that cleaves fatty acyl groups from proteins, the first fatty acylase discovered.
Protein Lipidation Protocols offers biochemists, cell and molecular biologists, medicinal chemists, and pharmaceutical researchers state-of-the-art tools for understanding the complex biochemistry of protein lipidation, as well as catalyzing the development of many important new biopharmaceuticals, including anticancer drugs.





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In Protein Lipidation Protocols, Michael Gelb brings together a collection of readily reproducible techniques for studying protein lipidation, the covalent attachment of lipids to proteins. These cutting-edge methods-many never published before in a "hands-on" format-deal with glycosyl phosphatidylinositol (GPI)-containing compounds, protein fatty acylation, and protein prenylation. Included are novel techniques for determining the chemical structure of GPI-anchors, for radiolabeling the prenyl groups of protein in eukaryotic cells, a tool for developing inhibitors of the protein farnesyltransferase, and for an exciting lysosomal enzyme that cleaves fatty acyl groups from proteins, the first fatty acylase discovered.
Protein Lipidation Protocols offers biochemists, cell and molecular biologists, medicinal chemists, and pharmaceutical researchers state-of-the-art tools for understanding the complex biochemistry of protein lipidation, as well as catalyzing the development of many important new biopharmaceuticals, including anticancer drugs.





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Verlag
Humana
Erscheinungsdatum
1999
Sprache
Englisch
ISBN 10 
0896035344
ISBN 13 
9780896035348
Einband
Gebundene Ausgabe
Anzahl der Seiten
250
Herausgeber
Gelb Michael H.
Kontakt zum Hersteller
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Europaplatz 3
Heidelberg
69115
Deutschland

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9781489943309: Protein Lipidation Protocols (Methods in Molecular Biology, Band 116)

Vorgestellte Ausgabe

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Verlag: Humana, 2013
Softcover