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Fluorouracil: Synthesis, Health Effects and Role in Chemotherapy: Synthesis, Health Effects & Role in Chemotherapy (Pharmacology Research Safety Testing and Regulation) - Hardcover

 
9781620819708: Fluorouracil: Synthesis, Health Effects and Role in Chemotherapy: Synthesis, Health Effects & Role in Chemotherapy (Pharmacology Research Safety Testing and Regulation)
Hardcover
ISBN 10: 1620819708 ISBN 13: 9781620819708
Verlag: Nova Science Publishers Inc, 2012

Inhaltsangabe

The fluoropyrimidine 5-fluorouracil (5-FU), an antimetabolite drug, works by being incorporated in the RNA and DNA and by the inhibition of the nucleotide synthetic enzyme thymidylate synthase. It is widely used in the treatment of a range of cancers, including gastrointestinal, head and neck, and breast cancers. In this book, the authors present current research in the study of the synthesis, health effects and role in chemotherapy of fluorouracil. Topics discussed include the antiproliferative activities, cell-cycle regulation, apoptosis and cellular differentiation of acyclic 5-fluorouracil O, N-Acetals; 5-fluorouracil and its immunotoxicity and side effects; 5-fluorouracil application in the management of bleb failure; and cisplatin and 5-fluorouracil for the treatment of ovarian adenocarcinoma.

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Verlag
Nova Science Publishers Inc
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
1620819708
ISBN 13 
9781620819708
Einband
Gebundene Ausgabe
Auflage
1
Anzahl der Seiten
148
Herausgeber
Longinho Alberto C. Dario, Dobreiro Sebastiao E. Britto
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Easy Access System Europe
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