A comparative evaluation of memory enhancing ability of Ocimum species - Softcover

Singh, Varinder; Kahol, Aditi; Shri, Richa

 
9783330652552: A comparative evaluation of memory enhancing ability of Ocimum species
Softcover
ISBN 10: 3330652551 ISBN 13: 9783330652552
Verlag: Scholars' Press, 2018

Inhaltsangabe

Plants are valued greatly as enhancers of cognitive functions. Plants rich in polyphenols hold great promise for management of neurodegenerative diseases. In this study, some common polyphenol-rich Ocimum species i.e. O. basilicum, O. gratissimum and O. sanctum were examined for their anti-amnesic potential. The extracts of the three selected species were examined employing in-vitro tests to determine their antioxidant and acetylcholinesterase capacity. On the basis of in-vitro results, the most active extract was further investigated for the memory enhancing activity using a mouse model of dementia. Ocimum basilicum extract had the highest total phenol content and demonstrated the most significant in-vitro antioxidant and acetylcholinesterase inhibitory potential. In the in-vivo studies, treatment with O. basilicum extract for 7 days improved memory impairment induced by scopolamine in animals along with significant reduction in AChE activity and oxidative stress parameters (reduced TBARS levels and increased GSH activity) in hippocampus and cortex region of brain. This may be developed as a cognition enhancer after detailed testing.

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Über die Autorin bzw. den Autor

Dr. Varinder Singh (from Department of Pharmaceutical Sciences and Drug Research, Punjabi University, India) is exploring natural medicine for the management of neurological disorders. Dr. Richa Shri, a professor of Pharmacognosy, believes that nature has an answer to all human needs and ailments; we only have to understand what nature is saying.

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Verlag
Scholars' Press
Erscheinungsdatum
2018
Sprache
Englisch
ISBN 10 
3330652551
ISBN 13 
9783330652552
Einband
Taschenbuch
Anzahl der Seiten
60
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Editions Vie
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
1039
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