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Regulation of Multidrug Resistance in Human Pathogen Candida albicans: Cellular Iron Homeostasis as a Novel Regulatory Mechansism of Multidrug Resistance (MDR) - Softcover

HAMEED, SAIF

 
9783844327960: Regulation of Multidrug Resistance in Human Pathogen Candida albicans: Cellular Iron Homeostasis as a Novel Regulatory Mechansism of Multidrug Resistance (MDR)
Softcover
ISBN 10: 3844327967 ISBN 13: 9783844327960
Verlag: LAP LAMBERT Academic Publishing, 2011

Inhaltsangabe

The dimorphic opportunistic pathogen,Candida albicans is normally a commensal organism in humans, but in immunocompromised individual,as in AIDS,organ transplant,diabetes,cancer patients,it results in systemic or invasive mycoses.Continuous exposure to antifungals has led to the emergence of drug resistance by a phenomenon termed as Multidrug Resistance (MDR).Much progress has been accomplished towards identification and understanding of drug resistance mechansisms that could make better antifungal agents. However,the need for understanding novel molecular mechanisms for MDR is indisputable in these clinically challenging infections by C.albicans. Although the importance of iron during C.albicans infection is known, mechanisms correlating about the influence of iron availability on MDR in this fungus are not reported yet. Since, MDR is a multifactorial phenomenon, iron mediated novel MDR mechanisms described in this book for pathogenic fungi clearly hold promise to be new potential drug regulatory mechanism so that it may facilitate the development of better antifungal strategies and thereby efficiently control the human infectious diseases.

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Über die Autorin bzw. den Autor

Research Associate, 2011: Jawaharlal Nehru University, New Delhi. Ph.D.(Life Sciences),2010: Jawaharlal Nehru University, New Delhi.Visiting Scholar,2008: Heinrich-Heine University, Dusseldorf, Germany. Masters (Biotechnology),2005: Dept of Biotechnology, Jamia Hamdard, New Delhi. Bachelors (Biomedical Sciences),2003: University of Delhi.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2011
Sprache
Englisch
ISBN 10 
3844327967
ISBN 13 
9783844327960
Einband
Taschenbuch
Anzahl der Seiten
248
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
SIA OmniScriptum Publishing
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
1039
Lettland