Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves.
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Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves.
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Hardcover. Zustand: Good. Oversized hardcover, xxiii + 1095 pages, colour illustrations in text, NOT ex-library. Yellow highlighting on 40 pages. A short pen line in side margin of one page, two lines on p.857. Other pages are clean. 6 straightened page corner folds. Binding is loosened but secure and stable. Boards show storage wear: scratches, two small areas of surface damage (rear panel), a couple of scuff-marks on lower edges, shelfwear. Published without a dust jacket. -- Contents: Structural Biology of TRP Channels; Functional and Structural Studies of TRP Channels Heterologously Expressed in Budding Yeast; Natural Product Ligands of TRP Channels; Synthetic Modulators of TRP Channel Activity; Study of TRP Channels by Automated Patch Clamp Systems; TRPC2: Of Mice But Not Men; TRPM1: New Trends for an Old TRP; Non-selective Monovalent Cationic Channels TRPm4 and TRPM5; TRPM7, the Mg2+ Inhibited Channel and Kinase; TRPM8 in Health and Disease: Cold Sensing and Beyond; TRPML1; TRPML2 and the Evolution of Mucolipins; TRPML3 Channel: From Gene to Function; TRPV5 and TRPV6 in Transcellular Ca2+ Transport: Regulation, Gene Duplication, and Polymorphisms in African Populations; TRPV5 Promoter as a Tool for Generation of Transgenic Mouse Models; TRPP Channels and Polycystins; TRP Channels in Yeast; C. elegans TRP Channels; Investigations of the In Vivo Requirements of Transient Receptor Potential Ion Channels Using Frog and Zebrafish Model Systems; TRP Channels in Parasites; Receptor Signaling Integration by TRP Channelsomes; Gating Mechanisms of Canonical Transient Receptor Potential Channel Proteins: Role of Phosphoinositols and Diacylglycerol; TRPC Ion Channels: Association with Orail and STIMI1 Proteins and Participation in Capacitative and Non-capacitative Calcium Entry; Contribution of TRPc1 and Orail to Ca2+ Entry Activated by Store Depletion; Primary Thermosensory Events in Cells; Thermo-TRP Channels: Biophysics of Polymodal Receptors; Complex Regulation of TRPv1 and Related Thermo-TRPs: Implications for Therapeutic Intervention; Voltage Sensing in Thermo-TRP Channels; TRP Channels as Mediators of Oxidative Stress; Regulation of TRP Signalling by Ion Channel Translocation Between Cell Compartments; Emerging Roles of Canonical TRP Channels in Neuronal Function; TRP Channels and Neural Persistent Activity; Role of TRP Channels in Pain Sensation; TRPV1: A Therapy Target That Attracts the Pharmaceutical Interests; Expression and Function of TRP Channels in Liver Cells; Expression and Physiological Roles of TRP Channels in Smooth Muscle Cells; TRPM Channels in the Vasculature; Molecular Expression and Functional Role of Canonical Transient Receptor Potential Channels in Airway Smooth Muscle Cells; TRP Channels in Skeletal Muscle: Gene Expression, function and Implications for Disease; TRP Channels in Vascular Endothelial Cells; TRP Channels in the Cardiopulmonary Vasculature; TRP Channels of Islets; Multiple Roles for TRPs in the Taste System: Not Your Typical TRPs; Roles of Transient Receptor Potential Proteins (TRPs) in Epidermal Keratinocytes; TRP Channels in Urinary Bladder Mechanosensation; Role of TRP Ion Channels in Testicular Function; TRP Channels in Female Reproductive Organs and Placenta; Oncogenic TRP Channels; TRPV Channels in Tumor Growth and Progression; Role of Transient Receptor Potential Channels in Respiratory Symptoms and Pathophysiology; TRP Channels and Psychiatric Disorders; Transient Receptor Potential Genes and Human Inherited Disease; Index. Bestandsnummer des Verkäufers 005221
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Hardcover. Zustand: new. Hardcover. Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves. Transient Receptor Potential Channels presents a synthesis of selected topics ranging from the structural biology of this fascinating group of ion channels. TRP channels of yeasts, flies, parasites, fishes, frogs and human are all included in one comprehensive text. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Bestandsnummer des Verkäufers 9789400702646
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves. 1124 pp. Englisch. Bestandsnummer des Verkäufers 9789400702646
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Buch. Zustand: Neu. Neuware -Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1124 pp. Englisch. Bestandsnummer des Verkäufers 9789400702646
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