Structure-Based Drug Design

Veerapandian, Pandi (EDT)

ISBN 10: 0824798694 / ISBN 13: 9780824798697

Verlag: Routledge, 1997

Unread book in perfect condition. Bestandsnummer des Verkäufers 765732

Inhaltsangabe:

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more!

Über die Autorin bzw. den Autor: Pandi Veerapandian

Bibliografische Details

Titel: Structure-Based Drug Design
Verlag: Routledge
Erscheinungsdatum: 1997
Einband: Hardcover
Zustand: As New