Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Pr, 2020
ISBN 10: 162182358X ISBN 13: 9781621823582
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Verlag: Cold Spring Harbor Laboratory Press, 2020
ISBN 10: 162182358X ISBN 13: 9781621823582
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Hardcover. Zustand: new. Hardcover. During embryonic development, amorphous cardiac precursor cells are organized into a rhythmically contracting, multi-chambered muscular structure, complete with valves, vessels, and a conduction system. This structure--the heart--is the first organ to form in vertebrate embryos, and all subsequent life processes depend on its proper function. But a range of genetic and environmental factors can disrupt proper heart development and lead to congenital heart disease, the most common birth defect. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology describes recent progress in our understanding of early heart development and the various cell lineages involved, as well as mechanisms and models of congenital heart disease. The contributors discuss early cardiac morphogenesis and anatomy, the origins of contractile activity, the control of cardiac growth and size, and the signaling pathways and transcription programs that underpin these processes. Specific chapters are devoted to various muscle and non-muscle cell lineages involved in heart development, including those of the neural crest, endo- and epicardium, fibroblasts, coronary vessels, and cardiac conduction and lymphatic systems. Insights from chickens, frogs, and reptiles--model organisms that support research in this area--are also covered. In addition, the authors examine congenital heart disease, genetic variants and environmental risk factors (e.g., teratogens and nutritional deficiencies) that disrupt normal heart development and cause various malformations, and the use of cell and animal model systems to study disease pathogenesis and test therapeutic interventions. This volume is therefore a valuable reference for all cell and developmental biologists, geneticists, and cardiologists who are interested in the early development and abnormalities of this complex, vital organ "A subject collection from Cold Spring Harbor Perspectives in Biology." Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press,U.S., US, 2020
ISBN 10: 162182358X ISBN 13: 9781621823582
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Verlag: Cold Spring Harbor Laboratory Pr, 2020
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ISBN 10: 162182358X ISBN 13: 9781621823582
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ISBN 10: 162182358X ISBN 13: 9781621823582
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Buch. Zustand: Neu. Neuware - Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology describes recent progress in our understanding of early heart development and the various cell lineages involved, as well as mechanisms and models of congenital heart disease. The contributors discuss early cardiac morphogenesis and anatomy, the origins of contractile activity, the control of cardiac growth and size, and the signaling pathways and transcription programs that underpin these processes. Specific chapters are devoted to various muscle and non-muscle cell lineages involved in heart development, including those of the neural crest, endo- and epicardium, fibroblasts, coronary vessels, and cardiac conduction and lymphatic systems.
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press,U.S., US, 2020
ISBN 10: 162182358X ISBN 13: 9781621823582
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Verlag: Belin, coll. « Géographie universelle », 1999
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Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press,U.S., New York, 2020
ISBN 10: 162182358X ISBN 13: 9781621823582
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Hardcover. Zustand: new. Hardcover. During embryonic development, amorphous cardiac precursor cells are organized into a rhythmically contracting, multi-chambered muscular structure, complete with valves, vessels, and a conduction system. This structure--the heart--is the first organ to form in vertebrate embryos, and all subsequent life processes depend on its proper function. But a range of genetic and environmental factors can disrupt proper heart development and lead to congenital heart disease, the most common birth defect. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology describes recent progress in our understanding of early heart development and the various cell lineages involved, as well as mechanisms and models of congenital heart disease. The contributors discuss early cardiac morphogenesis and anatomy, the origins of contractile activity, the control of cardiac growth and size, and the signaling pathways and transcription programs that underpin these processes. Specific chapters are devoted to various muscle and non-muscle cell lineages involved in heart development, including those of the neural crest, endo- and epicardium, fibroblasts, coronary vessels, and cardiac conduction and lymphatic systems. Insights from chickens, frogs, and reptiles--model organisms that support research in this area--are also covered. In addition, the authors examine congenital heart disease, genetic variants and environmental risk factors (e.g., teratogens and nutritional deficiencies) that disrupt normal heart development and cause various malformations, and the use of cell and animal model systems to study disease pathogenesis and test therapeutic interventions. This volume is therefore a valuable reference for all cell and developmental biologists, geneticists, and cardiologists who are interested in the early development and abnormalities of this complex, vital organ "A subject collection from Cold Spring Harbor Perspectives in Biology." Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Englisch.
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Buch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews.