F schmalzl (37 Ergebnisse)

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The origin and function of normal monocytes and macrophages have been clearly defined by extensive investigations in human and in animal models. The central importance ofthis cell system for the biological defense mecha nisms is well established: phagocytosis, inactivation and destruction of organic and inorganic materials, an important role in the initiation ofhumo ral and cell mediated immunological responses, and the secretion of a varie ty of chemical mediator and effector substances are the most important fea tures of this ontogenetically ancient cell system. However, the data on this cellular system are rather recent, and this may explain why relatively little attention has been payed to the pathology of the monocyte-macrophage system (MMS) until now. In addition, this monograph should focus attention on the secondarypa thophysiological implications of the MMS in disorders not primarily origi nating from this system. Several techniques are available to identify even abnormal individuals of this cell system and, therefore, can be employed for the study of severely altered or neoplastic monocytic cells.…

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Clinical hematologists are frequently faced with the intriguing problem of agnogenic myelo dysplastic syndromes; these syndromes are peculiar in their failing or poor response to therapy and in that they frequently terminate in acute leukemia. An international symposium held in Innsbruck in 1978 was dedicated to clinical and pathophysiologic aspects of the preleukemic syndromes. This monograph consists of articles that correspond to the papers presented at the symposium and of the edited discussions. It was the aim of the symposium and of this monograph to outline comprehensively the pathophysiologic background of the preleukemic syndromes and to summarize the present information about their clinical management. The first part of the monograph covers that pathology of these disorders: Disturbed maturation and proliferation of the hemopoietic cells are the causes of cyto penias, of structural and ultrastructural anomalies, and of enzymatic and functional defects. Further articles are concerned with the evaluation of these features and of chromosome anomalies as possible tools for the diagnostic and prognostic classification of myelodysplasias. Pathogenetic data and immunologic considerations form the rationale for therapeutic ap proaches. F. Schmalzl K. -P. Hellriegel v Contents K. -P. Hellriegel and F. Schmalzl Preleukemia: Definition and Classification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . H. Heirnpel Conventional Morphological Examination of Blood and Bone Marrow Cells in the Diagnosis of Preleukemic Syndromes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 C. Peschle Pure Red Cell Aplasia Type III: Progression to Acute Myeloid Leukemia and Absence of the IgG Inhibitor to Erythropoiesis . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Discussion . . . . . . . . . . . . . . . . . . '. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 . . . . I. Fohlmeister, H. E. Schaefer, K. -P. Hellriegel, and R.…

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Die lahrestagung der Deutschen Gesellschaft fUr Hiimatologie fand im Oktober 1976 nach 21 lahren zum erstenmal wieder in Freiburg statt. 1955 war der KongreBprasident unser unvergessener Ludwig Heitmeyer, der besonders auf dem Gebiete des Eisenstoffwechsels maBgebliche methodische und klinische Pionierarbeit geleistet hat. Die 3 Hauptthemen dieser Tagung sind daher teilweise durch den 'genius loci' mitbestimmt (Abb. 1). Abb.1. Ludwig Heilmeyer, 1899-1969 Der Eisenstoffwechsel ist schon seit der Frtihgeschichte ein Problem der Menschheit, dessen Storungen die haufigste Ursache fUr Bluterkrankungen darstellt. Die Phylogenese vom A vertebraten tiber die Vertebraten zum Men schen ware ohne das Auftreten des eisenhaltigen Hamoglobinmolekiils gar nicht moglich gewesen, schaffte es doch die Voraussetzung der reversiblen Oxygena tion und damit der zahlreichen Redox-Reaktionen aller einfachen und kompli zierten Gewebe und Korperorgane. Das so einfach erscheinende Eisenatom kommt in zwei-und dreiwertiger Form vor. Das_zweiwertige Eisen hat an seiner AuBenschale nur 6 d-Elektronen, das dreiwertige Eisen-Ion 5 d-Elektronen. Beide Eisenformen haben gewohnlich eine oktahedrale Koordination, wie aus der Abb. 2 hervorgeht. Vorwort x L, k-_____ -+------::::::==---::~L, L, '''''--=-----+----'~ Abb. 2. Modell des Eisenatoms L, In dieser Form ist das zentrale Metall-Ion umgeben durch vier Liganden-Ato me LI-L4 an den Ecken des Vierecks und hat auBerdem zwei zusatzliche Liganden-Atome L5 und L6.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The origin and function of normal monocytes and macrophages have been clearly defined by extensive investigations in human and in animal models. The central importance ofthis cell system for the biological defense mecha nisms is well established: phagocytosis, inactivation and destruction of organic and inorganic materials, an important role in the initiation ofhumo ral and cell mediated immunological responses, and the secretion of a varie ty of chemical mediator and effector substances are the most important fea tures of this ontogenetically ancient cell system. However, the data on this cellular system are rather recent, and this may explain why relatively little attention has been payed to the pathology of the monocyte-macrophage system (MMS) until now. In addition, this monograph should focus attention on the secondarypa thophysiological implications of the MMS in disorders not primarily origi nating from this system. Several techniques are available to identify even abnormal individuals of this cell system and, therefore, can be employed for the study of severely altered or neoplastic monocytic cells. 276 pp. Englisch.…

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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Pathophysiological Aspects.- Current View of the Mononuclear Phagocyte System.- The Kinetics of Mononuclear Phagocytes in Man.- Biochemical Properties of Human and Murine Mononuclear Phagocytes and Their Changes on Activation.- Macrophages in the Regulation.…

Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The origin and function of normal monocytes and macrophages have been clearly defined by extensive investigations in human and in animal models. The central importance ofthis cell system for the biological defense mecha nisms is well established: phagocytosis, inactivation and destruction of organic and inorganic materials, an important role in the initiation ofhumo ral and cell mediated immunological responses, and the secretion of a varie ty of chemical mediator and effector substances are the most important fea tures of this ontogenetically ancient cell system. However, the data on this cellular system are rather recent, and this may explain why relatively little attention has been payed to the pathology of the monocyte-macrophage system (MMS) until now. In addition, this monograph should focus attention on the secondarypa thophysiological implications of the MMS in disorders not primarily origi nating from this system. Several techniques are available to identify even abnormal individuals of this cell system and, therefore, can be employed for the study of severely altered or neoplastic monocytic cells.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 276 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Clinical hematologists are frequently faced with the intriguing problem of agnogenic myelo dysplastic syndromes; these syndromes are peculiar in their failing or poor response to therapy and in that they frequently terminate in acute leukemia. An international symposium held in Innsbruck in 1978 was dedicated to clinical and pathophysiologic aspects of the preleukemic syndromes. This monograph consists of articles that correspond to the papers presented at the symposium and of the edited discussions. It was the aim of the symposium and of this monograph to outline comprehensively the pathophysiologic background of the preleukemic syndromes and to summarize the present information about their clinical management. The first part of the monograph covers that pathology of these disorders: Disturbed maturation and proliferation of the hemopoietic cells are the causes of cyto penias, of structural and ultrastructural anomalies, and of enzymatic and functional defects. Further articles are concerned with the evaluation of these features and of chromosome anomalies as possible tools for the diagnostic and prognostic classification of myelodysplasias. Pathogenetic data and immunologic considerations form the rationale for therapeutic ap proaches. F. Schmalzl K. -P. Hellriegel v Contents K. -P. Hellriegel and F. Schmalzl Preleukemia: Definition and Classification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . H. Heirnpel Conventional Morphological Examination of Blood and Bone Marrow Cells in the Diagnosis of Preleukemic Syndromes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 C. Peschle Pure Red Cell Aplasia Type III: Progression to Acute Myeloid Leukemia and Absence of the IgG Inhibitor to Erythropoiesis . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Discussion . . . . . . . . . . . . . . . . . . '. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 . . . . I. Fohlmeister, H. E. Schaefer, K. -P. Hellriegel, and R. 212 pp. Englisch.…

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Preleukemia: Definition and Classification.- Conventional Morphological Examination of Blood and Bone Marrow Cells in the Diagnosis of Preleukemic Syndromes.- Pure Red Cell Aplasia Type III: Progression to Acute Myeloid Leukemia and Absence of the IgG Inhib.…

Taschenbuch. Zustand: Neu. Preleukemia | F. Schmalzl (u. a.) | Taschenbuch | xii | Englisch | 1980 | Springer | EAN 9783540096986 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand.…

Zustand: New. Print on Demand pp. 212 64 Figures, 67:B&W 6.69 x 9.61 in or 244 x 170 mm (Pinched Crown) Perfect Bound on White w/Gloss Lam.

Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -. . . . . . . . . 12 Discussion . . . . . . . . . . . . . . . . . . '. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 . . . . I. Fohlmeister, H. E. Schaefer, K. -P. Hellriegel, and R.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 212 pp. Englisch.…