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PAP. Zustand: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Zustand: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Zustand: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Zustand: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Zustand: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Zustand: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Taschenbuch. Zustand: Neu. Cancer Biology | Molecular Mechanisms, Genomic Evolution, Tumor Heterogeneity, and Therapeutic Response | MD Wiegand Falkner | Taschenbuch | Englisch | 2026 | W.F | EAN 9788091989831 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand. …

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Cancer is not simply uncontrolled cell growth. It is an evolving biological system in which genetic and epigenetic alterations reshape cellular behavior, disrupt tissue organization, alter interactions with the tumor microenvironment, and create populations capable of invasion, metastasis, persistence, and resistance to treatment.Cancer Biology presents cancer through this mechanistic framework, connecting molecular alterations to cellular behavior, tumor evolution, clinical phenotype, and therapeutic response.The book begins with the biological systems that normally regulate cellular growth, survival, differentiation, genomic integrity, and tissue organization. It then examines how these controls become disrupted through cancer genetics, oncogenes, tumor suppressor genes, DNA damage and repair defects, genomic instability, and epigenetic reprogramming.Particular attention is given to the evolutionary nature of cancer. Tumors are composed of genetically and phenotypically diverse populations that compete, adapt, and respond differently to changing conditions. Clonal evolution, tumor heterogeneity, cellular plasticity, cancer metabolism, replicative immortality, and treatment-driven selection are therefore considered as interconnected processes rather than isolated concepts.The biology of the tumor extends beyond the malignant cell. The tumor microenvironment, including cancer-associated fibroblasts, extracellular matrix, blood vessels, immune cells, inflammatory signals, oxygen availability, and metabolic conditions, can influence tumor growth, invasion, metastasis, immune evasion, and therapeutic response.The book also connects fundamental cancer biology with clinical practice, covering:Cancer genetics, genomics, mutations, copy-number alterations, gene fusions, and driver alterationsOncogenes and tumor suppressors, including TP53, RB, RAS-RAF-MEK-ERK, PI3K-AKT-mTOR, and WNT/ß-cateninDNA damage, DNA repair, replication stress, and genomic instabilityEpigenetic regulation, chromatin remodeling, cellular identity, and plasticityClonal evolution, tumor heterogeneity, cancer-cell states, and tumor persistenceCancer metabolism, hypoxia, angiogenesis, inflammation, and the tumor microenvironmentImmune surveillance, immune evasion, immunoediting, and tumor immunologyInvasion, metastasis, organ colonization, dormancy, residual disease, and recurrencePathology, molecular classification, biomarkers, liquid biopsy, staging, and early detectionCancer treatment, including surgery, radiation, cytotoxic, targeted, endocrine, and immune-based therapiesPrecision oncology, single-cell and spatial biology, functional genomics, artificial intelligence, and patient-derived modelsThe emphasis throughout is not merely on what changes in cancer, but on what those changes allow the cancer cell or tumor to do.…

Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Cancer is not simply uncontrolled cell growth. It is an evolving biological system in which genetic and epigenetic alterations reshape cellular behavior, disrupt tissue organization, alter interactions with the tumor microenvironment, and create populations capable of invasion, metastasis, persistence, and resistance to treatment.Cancer Biology presents cancer through this mechanistic framework, connecting molecular alterations to cellular behavior, tumor evolution, clinical phenotype, and therapeutic response.The book begins with the biological systems that normally regulate cellular growth, survival, differentiation, genomic integrity, and tissue organization. It then examines how these controls become disrupted through cancer genetics, oncogenes, tumor suppressor genes, DNA damage and repair defects, genomic instability, and epigenetic reprogramming.Particular attention is given to the evolutionary nature of cancer. Tumors are composed of genetically and phenotypically diverse populations that compete, adapt, and respond differently to changing conditions. Clonal evolution, tumor heterogeneity, cellular plasticity, cancer metabolism, replicative immortality, and treatment-driven selection are therefore considered as interconnected processes rather than isolated concepts.The biology of the tumor extends beyond the malignant cell. The tumor microenvironment, including cancer-associated fibroblasts, extracellular matrix, blood vessels, immune cells, inflammatory signals, oxygen availability, and metabolic conditions, can influence tumor growth, invasion, metastasis, immune evasion, and therapeutic response.The book also connects fundamental cancer biology with clinical practice, covering:Cancer genetics, genomics, mutations, copy-number alterations, gene fusions, and driver alterationsOncogenes and tumor suppressors, including TP53, RB, RAS-RAF-MEK-ERK, PI3K-AKT-mTOR, and WNT/ß-cateninDNA damage, DNA repair, replication stress, and genomic instabilityEpigenetic regulation, chromatin remodeling, cellular identity, and plasticityClonal evolution, tumor heterogeneity, cancer-cell states, and tumor persistenceCancer metabolism, hypoxia, angiogenesis, inflammation, and the tumor microenvironmentImmune surveillance, immune evasion, immunoediting, and tumor immunologyInvasion, metastasis, organ colonization, dormancy, residual disease, and recurrencePathology, molecular classification, biomarkers, liquid biopsy, staging, and early detectionCancer treatment, including surgery, radiation, cytotoxic, targeted, endocrine, and immune-based therapiesPrecision oncology, single-cell and spatial biology, functional genomics, artificial intelligence, and patient-derived modelsThe emphasis throughout is not merely on what changes in cancer, but on what those changes allow the cancer cell or tumor to do. 522 pp. Englisch.…

Taschenbuch. Zustand: Neu. Cellular and Molecular Immunology | Mechanisms of Immune Recognition, Cellular Decision-Making, Tissue Responses, and Disease | MD Wiegand Falkner | Taschenbuch | Englisch | 2026 | W.F | EAN 9782528544495 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand. …

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Immunology is not a catalog of cells, cytokines, receptors, and pathways. It is the study of how biological information is recognized, interpreted, and converted into action.Cellular and Molecular Immunology examines the immune system at precisely that level: how molecular signals become cellular decisions, how those decisions lead to tissue responses, and how their failure or redirection result in disease.The book is built around a mechanistic question that remains central across immunology: what information does an immune cell receive, how is that information integrated, and why does the cell respond in one way rather than another That question provides a consistent framework for understanding innate immune sensing, antigen recognition, signal transduction, lymphocyte development, immune tolerance, inflammation, cellular differentiation, antibody responses, immunological memory, tissue immunity, and immune-mediated pathology.Molecular mechanisms are examined where they determine biological behavior. TCR and BCR signaling, JAK-STAT, NF-¿B, MAPK, PI3K-AKT-mTOR, complement, interferon signaling, inflammasomes, antigen processing, MHC biology, V(D)J recombination, costimulation, inhibitory signaling, and metabolic regulation are treated as functional mechanisms rather than disconnected pathways to memorize.The same logic is carried into disease.Autoimmunity is examined as a failure of tolerance and regulatory control. Immunodeficiency is approached through the specific immune function that has been lost and the phenotype that follows. Infection is analyzed according to the pathogen's location, replication strategy, immune evasion mechanisms, and the balance between microbial control and tissue injury. Cancer is considered within the reciprocal relationship between tumor evolution and immune selection. Transplantation is framed through allorecognition, rejection, tolerance, and the consequences of donor-recipient immune conflict.The final part connects these mechanisms to immune-based medicine: monoclonal and bispecific antibodies, cytokine-targeted therapy, checkpoint blockade, cellular immunotherapies, vaccines, immune biomarkers, immune-repertoire analysis, single-cell technologies, and precision immunology.The objective is not to make immunology simpler by removing its complexity. It is to make that complexity structurally intelligible.…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - What happens when the body's automatic systems stop regulating themselves properly Autonomic Dysfunction provides a clear, medically grounded guide to dysautonomia, autonomic nervous system disorders, and autonomic dysfunction-from how normal autonomic regulation works to what happens when that regulation fails.Explore the mechanisms behind orthostatic intolerance, POTS, orthostatic hypotension, autonomic neuropathy, abnormal sweating, gastrointestinal dysfunction, bladder and sexual dysfunction, and cardiovascular autonomic symptoms.Written for readers who want more than a list of symptoms, this book connects autonomic physiology, clinical patterns, causes, diagnosis, testing, treatment, and everyday management in one accessible framework.Whether you are a patient trying to understand unexplained symptoms, a nursing or allied-health student, a health educator, or simply seeking a deeper understanding of dysautonomia, this book provides a practical foundation for understanding how the autonomic nervous system regulates the body-and what happens when that regulation becomes disrupted.…

Taschenbuch. Zustand: Neu. Autonomic Dysfunction | A Complete Guide to Dysautonomia, POTS, and Autonomic Nervous System Disorders | MD Wiegand Falkner | Taschenbuch | Englisch | 2026 | W.F | EAN 9784952082840 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand. …