Optimieren Sie Ihre Suche

bis

Benutzerdefinierte Preisspanne (EUR)

bis

Fox brian w (27 Ergebnisse)

Autor: 
Mit der Detailsuche verfeinern
  • Weitere Bilder

    Sprache: Englisch

    Verlag: W. Paul Ganley, Buffalo, NY, 1987

    • Softcover
    • Erstausgabe
    • Magazin / Zeitschrift

    Anbieter: biblioboy, North Providence, RI, USAbiblioboy

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Sehr gut

    EUR 9,23

    EUR 6,27 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Single Issue Magazine. Zustand: Fine. 1st Edition. W. Paul Ganley , NY , 1987 First Edition 62 page Vintage Fantasy Magazine Contents page in Photos . Front Cover Art by Stephen Fabian, Rear Cover art by Allen Koszowski A fine copy. See Photos mag 34. Cover Art by Stephen Fabian (illustrator).

  • Sprache: Englisch

    Verlag: North-Holland, 1978

    • Softcover

    Anbieter: BookDepart, Shepherdstown, WV, USABookDepart

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Befriedigend

    EUR 17,57

    EUR 7,57 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Soft cover. Zustand: UsedGood. Softcover; North-Holland; surplus library copy with the usual stampings; re ference numbers taped to spine; binding cocked; tears at ends of spine; oth erwise in good condition with clean text.

  • Verlag: W. Paul Ganley, Buffalo, NY, 1991

    • Softcover
    • Magazin / Zeitschrift

    Anbieter: Books from the Crypt, N. Potomac, MD, USABooks from the Crypt

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Verbandsmitglied: IOBA

    Zustand: Gebraucht - Gut bis sehr gut

    EUR 13,85

    EUR 4,93 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Wraps. Zustand: Near Fine. Very Good+ to Near Fine. Stapled wraps with dj. Cover art, dj is same as front cover, by Stepen E. Fabian. Includes "Dagon's Bell" by Brian Lumley; "Vacation Dreams" by Joseph Payne Brennan; "Devil God" by Lee Barwood; "The Santa" by Jessica Amanda Salmonson; "Shards of Midnight' by Steven G. Mitchell; "Three Brothers" by Darrell Schweitzer; "Her New Parents" by Steve Rasnic Tem; "The Stolen Prince" by Robert D. San Souci; "The Following" by John Brizzolara; "vendriel and Vendreela" by Brian McNaughton; "Too Much Night' by Gerald W. Page; "The Man Who Loved the Wizard's Son" by Janet Fox; "The Red Wind" by Al Sarrantonio; "Weaver of Mars" by Adrian Cole; "The Tower in the Jungle" by R. E. Klein; "As Blood Is It Red" by Delia Sherman; "Godfall" by John Gregory Betancourt; "Worm of Urakhu" by Richard L. Tierney. Poems by joseph payne Brennan, R. R. metcalf, Jr., and more. Illustrated by M. Kimes, Duane Allen, Greg keller, Rodolfo Ferraresi, Adrien Rain, Rodge Gerberging, A. Koszowski, A. G. Farnell, Mark bell, D. Plamondeon, Jon Bush, Jean Corbin, Tony Patrick, Ole Petterson, J. D. Garrison, J. K. Potter, Chris Friend, Larry Nadolsjy, Dallas Goffin, R. Lumley, and Tarkas. Edgewear to dj with small tear at spine panel head. Magazine.…

  • Sprache: Englisch

    Verlag: Springer, 1984

    3540130691 / 9783540130697

    • Hardcover

    Anbieter: Anybook.com, Lincoln, Vereinigtes KönigreichAnybook.com

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Befriedigend

    EUR 15,40

    EUR 18,59 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: 1 verfügbar

    Zustand: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1600grams, ISBN:3540130691.…

  • Zustand: Gebraucht - Gut

    EUR 13,80

    EUR 8,92 Versand 
    Versand von Kanada nach USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Soft cover. Zustand: Very Good. First Paperback Printings. (xii, viii) 338, 296 pp. Both books have light edge and corner wear with uncreased spines; no interior markings. Covers by Karel Thole. These anthologies contain: VOLUME ONE: Been a Long, Long Time by R. A. Lafferty; The Possessed by Arthur C. Clarke; Protected Species by H. B. Fyfe; All the Way Back by Michael Shaara; The Star Plunderer - a novelette by Poul Anderson; Foundation - a novelette by Isaac Asimov; We're Civilized by Alex Apostolides and Mark Clifton; The Crime and Glory of Commander Suzdal by Cordwainer Smith; The Rebel of Valkyr - a novella by Alfred Coppel; Brightness Falls from the Air by Margaret St. Clair writing as Idris Seabright; Immigrant - a novella by Clifford D. Simak; Resident Physician - a novelette by James White; Age of Retirement by Hal Lynch; and Planting Time by Pete Adams and Charles Nightingale. VOLUME TWO: Escape to Chaos - a novella by John D. MacDonald; Concealment by A. E. van Vogt; To Civilize by Algis Budrys; Beep - a novelette by James Blish; Down the River by Mack Reynolds; The Bounty Hunter by Avram Davidson; Not Yet the End by Fredric Brown; Tonight the Stars Revolt - a novella by Gardner F. Fox; Final Encounter by Harry Harrison; Lord of a Thousand Suns - a novelette by Poul Anderson; Big Ancestor - a novelette by F. L. Wallace; and The Interlopers by Roger Dee. Both volumes contain an assortment of essays by Brian W. Aldiss. Karel Thole; (illustrator). Book.…

  • Zustand: Gebraucht - Gut

    EUR 18,42

    EUR 8,92 Versand 
    Versand von Kanada nach USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Hardcover. Zustand: Very Good. Zustand des Schutzumschlags: Very Good. Book Club Editions. (xii, viii) 305, 278 pp. Book One has black boards lettered in gray on the spine; Book Two is quarter-bound in dark blue on light blue boards; lettered in lavender on the spine. Both dustjackets have light wear at the corners. Dj art by Karel Thole. These anthologies contain: VOLUME ONE: Been a Long, Long Time by R. A. Lafferty; The Possessed by Arthur C. Clarke; Protected Species by H. B. Fyfe; All the Way Back by Michael Shaara; The Star Plunderer - a novelette by Poul Anderson; Foundation - a novelette by Isaac Asimov; We're Civilized by Alex Apostolides and Mark Clifton; The Crime and Glory of Commander Suzdal by Cordwainer Smith; The Rebel of Valkyr - a novella by Alfred Coppel; Brightness Falls from the Air by Margaret St. Clair writing as Idris Seabright; Immigrant - a novella by Clifford D. Simak; Resident Physician - a novelette by James White; Age of Retirement by Hal Lynch; and Planting Time by Pete Adams and Charles Nightingale. VOLUME TWO: Escape to Chaos - a novella by John D. MacDonald; Concealment by A. E. van Vogt; To Civilize by Algis Budrys; Beep - a novelette by James Blish; Down the River by Mack Reynolds; The Bounty Hunter by Avram Davidson; Not Yet the End by Fredric Brown; Tonight the Stars Revolt - a novella by Gardner F. Fox; Final Encounter by Harry Harrison; Lord of a Thousand Suns - a novelette by Poul Anderson; Big Ancestor - a novelette by F. L. Wallace; and The Interlopers by Roger Dee. Both volumes contain an assortment of essays by Brian W. Aldiss. Size: 8vo. Karel Thole; (illustrator). Book.…

  • Zustand: Gebraucht - Gut

    EUR 18,42

    EUR 8,92 Versand 
    Versand von Kanada nach USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Hardcover. Zustand: Very Good. Zustand des Schutzumschlags: Very Good. Book Club Editions. (xii, viii) 305, 278 pp. Book One has black boards; Book Two is quarter-bound in dark blue on light blue boards; both are lettered in lavender on the spine. Both dustjackets have some wear at the corners; no interior markings. Dj art by Karel Thole. These anthologies contain: VOLUME ONE: Been a Long, Long Time by R. A. Lafferty; The Possessed by Arthur C. Clarke; Protected Species by H. B. Fyfe; All the Way Back by Michael Shaara; The Star Plunderer - a novelette by Poul Anderson; Foundation - a novelette by Isaac Asimov; We're Civilized by Alex Apostolides and Mark Clifton; The Crime and Glory of Commander Suzdal by Cordwainer Smith; The Rebel of Valkyr - a novella by Alfred Coppel; Brightness Falls from the Air by Margaret St. Clair writing as Idris Seabright; Immigrant - a novella by Clifford D. Simak; Resident Physician - a novelette by James White; Age of Retirement by Hal Lynch; and Planting Time by Pete Adams and Charles Nightingale. VOLUME TWO: Escape to Chaos - a novella by John D. MacDonald; Concealment by A. E. van Vogt; To Civilize by Algis Budrys; Beep - a novelette by James Blish; Down the River by Mack Reynolds; The Bounty Hunter by Avram Davidson; Not Yet the End by Fredric Brown; Tonight the Stars Revolt - a novella by Gardner F. Fox; Final Encounter by Harry Harrison; Lord of a Thousand Suns - a novelette by Poul Anderson; Big Ancestor - a novelette by F. L. Wallace; and The Interlopers by Roger Dee. Both volumes contain an assortment of essays by Brian W. Aldiss. Size: 8vo. Karel Thole; (illustrator). Book.…

  • Zustand: Gebraucht - Gut bis sehr gut

    EUR 23,08

    EUR 4,93 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Softcover. Zustand: Near Fine. First Edition. Magazine. Octavo. 92pp. Printed wrappers. Rubbing with small marks on the front wrapper, near fine. This issue features Thom Gunn, D.M. Thomas, Peter Scupham, Gavin Bantock, Patience Tuckwell, John Cotton, Roy MacGregor-Hastie, David H.W. Grubb, and Adam Fox. Additional contributors include David Lambourne, George Herbert, Stefane Mallarme, Stefan Themerson, Paula Claire,Christopher Hampton, May Ivimy, Brenda La Rosa, Brian Peters, G.W. Ashby, Martin Booth, Donald Ward, Odette Tchernine, John Smith, Ronald Bottrall, Paul Lester, James Bernardin, Walter Bennett, Vashti Tyrrell, and Robert Garioch.…

  • Sprache: Englisch

    Verlag: Springer, Berlin, 1984

    0387130691 / 9780387130699

    • Hardcover

    Anbieter: Mike's Library LLC, Plymouth, PA, USAMike's Library LLC

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Gut

    EUR 46,12

     Versand gratis 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    Hardcover. Zustand: Very Good. No Dust Jacket. Library stamps/marks/labels/slip, otherwise light wear. Solid hardcover.; "It appears that the phenomenon of true resistance to a drug, as the biochemist would recognise it, is an important cause of the failure which clinicians experience in treating the disease. The extent of the contribution of this phenomenon to the failure of treatment cannot easily be evaluated at the present time, but it is hoped that the development and application of new and more sophisticated techniques for the analysis of cellular subpopulations may help to give a more exact estimate and to shed some light on the causes of failure of many of the present therapeutic techniques." - Preface ; Handbook Of Experimental Pharmacology; Ex-Library; Vol. 72; 745 pages.…

  • Sprache: Englisch

    Verlag: Springer Verlag;, 1984

    3540130691 / 9783540130697

    • Hardcover

    Anbieter: books4less (Versandantiquariat Petra Gros GmbH & Co. KG), Welling, Deutschlandbooks4less (Versandantiquariat Petra Gros GmbH & Co. KG)

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Gut

    EUR 12,99

    EUR 34,95 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    gebundene Ausgabe. Zustand: Gut. 738 Seiten Der Erhaltungszustand des hier angebotenen Werks ist trotz seiner Bibliotheksnutzung sehr sauber und kann entsprechende Merkmale aufweisen (Rückenschild, Instituts-Stempel.). In ENGLISCHER Sprache. Sprache: Englisch Gewicht in Gramm: 1570.

  • Sprache: Englisch

    Verlag: Insight Editions, 2024

    9798886636451

    • Hardcover

    Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 49,03

    EUR 2,37 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    Zustand: New.

  • Sprache: Englisch

    Verlag: Insight Editions, 2024

    9798886636451

    • Hardcover

    Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Wie neu

    EUR 54,77

    EUR 2,37 Versand 
    Versand innerhalb von USA

    Anzahl: 1 verfügbar

    Zustand: As New. Unread book in perfect condition.

  • Sprache: Englisch

    Verlag: Insight Editions, 2024

    9798886636451

    • Hardcover

    Anbieter: GreatBookPricesUK, Woodford Green, Vereinigtes KönigreichGreatBookPricesUK

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 42,83

    EUR 17,92 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: New.

  • Sprache: Englisch

    Verlag: Insight Editions, 2024

    9798886636451

    • Hardcover

    Anbieter: GreatBookPricesUK, Woodford Green, Vereinigtes KönigreichGreatBookPricesUK

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Wie neu

    EUR 49,89

    EUR 17,92 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: As New. Unread book in perfect condition.

  • Weitere Bilder

    Zustand: Gebraucht - Gut

    EUR 45,24

    EUR 7,08 Versand 
    Versand von Kanada nach USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Soft cover. Zustand: Very Good +. First Edition By This Publisher. The WILD BUNCH ( Movie Tie-in for the Sam Peckinpah directed film, Starring; William Holden, Robert Ryan, Ernest Borgnine, Edmond O'Brien & Warren Oates); SCARCE Title; >>> Minor cover creasing; Size: 12mo - over 6¾" - 7¾" tall. PHOTO Cover (illustrator). Book. …

  • Weitere Bilder

    Zustand: Gebraucht - Gut

    EUR 55,37

    EUR 29,87 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: 1 verfügbar

    Hardcover. Zustand: Very Good. 2005 John & Erica Hedges large format hardcover edition. Light reading wear else very good condition.

  • Sprache: Englisch

    Verlag: Springer Nature, 1984

    0387130691 / 9780387130699

    • Hardcover

    Anbieter: Phatpocket Limited, Waltham Abbey, HERTS, Vereinigtes KönigreichPhatpocket Limited

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Gebraucht - Befriedigend

    EUR 82,85

    EUR 12,71 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: 2 verfügbar

    Zustand: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.…

  • Weitere Bilder

    Zustand: Gebraucht

    EUR 54,47

    EUR 7,08 Versand 
    Versand von Kanada nach USA

    Anzahl: 1 verfügbar

    In den Warenkorb

    Soft cover. Zustand: Very Good to Fine. First Edition By This Publisher. The WILD BUNCH ( Movie Tie-in for the Sam Peckinpah directed film, Starring; William Holden, Robert Ryan, Ernest Borgnine, Edmond O'Brien & Warren Oates); SCARCE Title; >>> Minor staing to right edge of spine. minor scuffing to covers. Size: 12mo - over 6¾" - 7¾" tall. PHOTO Cover (illustrator). Book.…

  • Sprache: Englisch

    Verlag: Springer, 2011

    3642694926 / 9783642694929

    • Softcover

    Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes KönigreichRia Christie Collections

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 131,30

    EUR 17,85 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: New. In English.

  • Sprache: Englisch

    Verlag: Springer, 2011

    3642694926 / 9783642694929

    • Softcover

    Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 124,85

    EUR 44,14 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The study of tumour resistance to anticancer drugs has been the subject of many publications since the initial discovery of the phenomenon by J. H. Burchenal and colleagues in 1950. Many papers have been published since then reporting development of resistance to most of the well-known anticancer agents in many different animal tumour systems, both in vivo and in vitro. Many different mechanisms of resistance have been described, and it is clear that the tumour cell has a wide diversity of options in overcoming the cell-killing activity of these agents. Definition of the magnitude of the phenomenon in the clinic is, however, much more problematical, and it is with this in mind that the initial chapter, seeks to out line the problem as the clinicians see it. It appears that the phenomenon of true resistance to a drug, as the biochemist would recognise it, is an important cause of the failure which clinicians experience in treating the disease. The extent of the contribution of this phenomenon to the failure of treatment cannot easily be evaluated at the present time, but it is hoped that the development and application of new and more sophisticated techniques for the analysis of cellular sub populations may help to give a more exact estimate and to shed some light on the causes of failure of many of the present therapeutic techniques.…

  • Zustand: Neu

    EUR 167,60

    EUR 17,92 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: 2 verfügbar

    Paperback. Zustand: Brand New. reprint edition. 763 pages. 9.25x6.75x1.75 inches. In Stock.

  • Zustand: Gebraucht - Gut

    EUR 179,99

    EUR 39,95 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    Hardcover. Zustand: gut. 1984. Antitumor Drug Resistance (Handbook of Experimental Pharmacology. Continuation of Handbuch der experimentellen Pharmakologie, Vol. 72) In deutscher Sprache. pages.

  • Sprache: Englisch

    Verlag: Createspace Independent Publishing Platform, 2012

    1478397810 / 9781478397816

    • Softcover
    • Print-on-Demand

    Anbieter: THE SAINT BOOKSTORE, Southport, Vereinigtes KönigreichTHE SAINT BOOKSTORE

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 13,20

    EUR 15,59 Versand 
    Versand von Vereinigtes Königreich nach USA

    Anzahl: Mehr als 20 verfügbar

    Paperback / softback. Zustand: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days. Armstrong, Helen (illustrator).

  • Sprache: Englisch

    Verlag: Springer, 2011

    3642694926 / 9783642694929

    • Softcover
    • Print-on-Demand

    Anbieter: Brook Bookstore On Demand, Napoli, NA, ItalienBrook Bookstore On Demand

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 86,24

    EUR 11,00 Versand 
    Versand von Italien nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: new. Questo è un articolo print on demand.

  • Sprache: Englisch

    Verlag: Springer, Springer Dez 2011, 2011

    3642694926 / 9783642694929

    • Softcover
    • Print-on-Demand

    Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, DeutschlandBuchWeltWeit Ludwig Meier e.K.

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 106,99

    EUR 23,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 2 verfügbar

    Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study of tumour resistance to anticancer drugs has been the subject of many publications since the initial discovery of the phenomenon by J. H. Burchenal and colleagues in 1950. Many papers have been published since then reporting development of resistance to most of the well-known anticancer agents in many different animal tumour systems, both in vivo and in vitro. Many different mechanisms of resistance have been described, and it is clear that the tumour cell has a wide diversity of options in overcoming the cell-killing activity of these agents. Definition of the magnitude of the phenomenon in the clinic is, however, much more problematical, and it is with this in mind that the initial chapter, seeks to out line the problem as the clinicians see it. It appears that the phenomenon of true resistance to a drug, as the biochemist would recognise it, is an important cause of the failure which clinicians experience in treating the disease. The extent of the contribution of this phenomenon to the failure of treatment cannot easily be evaluated at the present time, but it is hoped that the development and application of new and more sophisticated techniques for the analysis of cellular sub populations may help to give a more exact estimate and to shed some light on the causes of failure of many of the present therapeutic techniques. 772 pp. Englisch.…

  • Zustand: Neu

    EUR 92,27

    EUR 48,99 Versand 
    Versand von Deutschland nach USA

    Anzahl: Mehr als 20 verfügbar

    Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. With contributions by numerous expertsThe study of tumour resistance to anticancer drugs has been the subject of many publications since the initial discovery of the phenomenon by J. H. Burchenal and colleagues in 1950. Many papers have been published . …

  • Sprache: Englisch

    Verlag: Springer, Springer Dez 2011, 2011

    3642694926 / 9783642694929

    • Softcover
    • Print-on-Demand

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschlandbuchversandmimpf2000

    Verkäufer/-in mit 5 Sternen
    Verkäufer/-in kontaktieren

    Zustand: Neu

    EUR 106,99

    EUR 60,00 Versand 
    Versand von Deutschland nach USA

    Anzahl: 1 verfügbar

    Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The study of tumour resistance to anticancer drugs has been the subject of many publications since the initial discovery of the phenomenon by J. H. Burchenal and colleagues in 1950. Many papers have been published since then reporting development of resistance to most of the well-known anticancer agents in many different animal tumour systems, both in vivo and in vitro. Many different mechanisms of resistance have been described, and it is clear that the tumour cell has a wide diversity of options in overcoming the cell-killing activity of these agents. Definition of the magnitude of the phenomenon in the clinic is, however, much more problematical, and it is with this in mind that the initial chapter, seeks to out line the problem as the clinicians see it. It appears that the phenomenon of true resistance to a drug, as the biochemist would recognise it, is an important cause of the failure which clinicians experience in treating the disease. The extent of the contribution of this phenomenon to the failure of treatment cannot easily be evaluated at the present time, but it is hoped that the development and application of new and more sophisticated techniques for the analysis of cellular sub populations may help to give a more exact estimate and to shed some light on the causes of failure of many of the present therapeutic techniques.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 772 pp. Englisch.…