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Zustand: New. KlappentextThis Scientific Publication reviews the information on cancer sites and mechanistic events for the more than 100 agents classified in Group 1 (carcinogenic to humans) by the IARC Monographs Program. This category of agents is .

Taschenbuch. Zustand: Neu. Neuware - This Scientific Publication reviews the information on cancer sites and mechanistic events for the more than 100 agents classified in Group 1 (carcinogenic to humans) by the IARC Monographs Program. This category of agents is diverse and includes chemicals and chemical mixtures; occupations; metals, dusts, and fibres; radiation; viruses and other biological agents; personal habits; and pharmaceuticals. For the Group 1 agents, there were cross-cutting questions about the relevance to humans of certain cancer sites or mechanistic pathways in animals. This publication is based on a systematic identification and comparison of the cancer sites observed in humans and those observed in experimental animals, and a compilation of mechanistic events for agents known to cause cancer in humans. Relevant information was analyzed on all the agents classified in Group 1 in Monographs up to and including Volume 109, most of which are reviewed in Volume 100A-F. A database of tumor sites seen in humans and animals was used to examine the degree of concordance by use of an anatomically based tumor classification scheme. The analysis of mechanistic aspects of the IARC Group 1 agents focused on 10 key characteristics of human carcinogens developed during the course of this work. Genotoxicity was the most prevalent mechanistic characteristic, consistent with the process of carcinogenesis necessarily involving genomic changes. The IARC concordance database represents a useful source of information for comparing animal and human data with respect to the tumors caused in different species. The results of the mechanistic analysis can provide a basis for future efforts to categorize mechanistic data for carcinogens through a systematic review process. These reviews and analyses were discussed during a two-part Workshop on Tumour Site Concordance and Mechanisms of Carcinogenesis convened by IARC. This Scientific Publication is the report of that Workshop and of subsequent work by the participants, both individually and collectively. This publication also presents a statement of consensus among the Workshop participants, which summarizes the main findings and their implications for human cancer risk assessment.…

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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. &Uumlber den AutorAndrea Vicini, SJ, is Chairperson, Michael P. Walsh Professor of Bioethics, and Professor of Theological Ethics in the Theology Department at Boston College. He also holds a M.D. from the University of Bologna and a S.…

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Buch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The Global Theological Ethics book series focuses on works that feature authors from around the world, draw on resources from the traditions of Catholic theological ethics, and attend to concrete issues facing the world today. It advances the Journal of Moral Theology's mission of fostering scholarship deeply rooted in traditions of inquiry about the moral life, engaged with contemporary issues, and exploring the interface of Catholic moral theology, philosophy, economics, political philosophy, psychology, and more.…

Buch. Zustand: Neu. The Rising Global Cancer Pandemic | Andrea S. J. Vicini (u. a.) | Buch | Global Theological Ethics | Gebunden | Englisch | 2023 | Pickwick Publications | EAN 9781666753363 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.…