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Ed. CALASANCIAS; Salamanca. 1977. Castellano. Rustica ilustrada con solapas. 24x17 cms. 413 pags. 1ª Edición. Con láminas al márgen del texto con ilustraciones en monocolor, algunas son reproducciones manuscritas. Etiqueta en lomo de anterior propietario. Muy buen estado. RELIGION. EPISTOLAR. BIOGRAFIA. Ref. 9203.
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In den WarenkorbZustand: New. pp. 468 Illus.
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Zustand: New. pp. 441.
Zustand: New. Editor(s): Lecea, Luis de (The Scripps Research Institute La Jolla); Sutcliffe, J. Gregor (The Scripps Research Institute La Jolla). Num Pages: 465 pages, 11 black & white tables, biography. BIC Classification: MJG; MJN; PSAN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 24. Weight in Grams: 712. . 2014. Paperback. . . . .
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Taschenbuch. Zustand: Neu. Hypocretins | Integrators of Physiological Signals | J. Gregor Sutcliffe (u. a.) | Taschenbuch | xxiv | Englisch | 2014 | Springer US | EAN 9781461498063 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Zustand: New. Editor(s): Lecea, Luis de (The Scripps Research Institute La Jolla); Sutcliffe, J. Gregor (The Scripps Research Institute La Jolla). Num Pages: 465 pages, 11 black & white tables, biography. BIC Classification: MJG; MJN; PSAN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 24. Weight in Grams: 712. . 2014. Paperback. . . . . Books ship from the US and Ireland.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with 'wide awake' EEG patterns and EMG suppression. The first report linking REM sleep to a pathology occurred in 1961 and a clear association of sleep onset REM periods, cataplexy, hypnagogic hallucinations and sleep paralysis was fully established by 1966. When a naïve individual happens to observe a full-blown cataplexy attack, it is both dramatic and unnerving. Usually the observer assumes that the loss of muscle tone represents syncope or seizure. In order to educate health professionals and the general public, Christian Guilleminault and I made movies of full-blown cataplectic episodes (not an easy task). We showed these movies of cataplexy attacks to a number of professional audiences, and were eventually rewarded with the report of a similar abrupt loss of muscle tone in a dog. We were able to bring the dog to Stanford University and with this as the trigger, we were able to develop the Stanford Canine Narcolepsy Colony. Breeding studies revealed the genetic determinants of canine narcolepsy, an autosomal recessive gene we termed canarc1. Emmanuel Mignot took over the colony in 1986 and began sequencing DNA, finally isolating canarc1 in 1999.
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The hypocretins (orexins) are a newly identified (1998) peptide family comprised of two peptides, hypocretin-1 and hypocretin-2. Recent observations suggest an involvement of these peptides, located primarily in the hypothalmus, in the regulation of behavioral state. They are involved in circadian rhythms, metabolism, hormone secretion, body temperature, appetite, cardiovascular functions (e.g., blood pressure), and sleep abnormalities (e.g., narcolepsy and cataplexy).
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Sprache: Englisch
Verlag: Springer International Publishing AG, Cham, 2017
ISBN 10: 3319575341 ISBN 13: 9783319575346
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Erstausgabe
Hardcover. Zustand: new. Hardcover. This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians. This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
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Taschenbuch. Zustand: Neu. Behavioral Neuroscience of Orexin/Hypocretin | Andrew J Lawrence (u. a.) | Taschenbuch | Current Topics in Behavioral Neurosciences | viii | Englisch | 2018 | Springer | EAN 9783319861876 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Anbieter: Mispah books, Redhill, SURRE, Vereinigtes Königreich
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In den WarenkorbHardcover. Zustand: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
Zustand: New. 1st ed. 2017 edition NO-PA16APR2015-KAP.
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Sprache: Englisch
Verlag: Springer International Publishing, 2018
ISBN 10: 3319861875 ISBN 13: 9783319861876
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who willprovide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians.
Sprache: Englisch
Verlag: Springer International Publishing, 2017
ISBN 10: 3319575341 ISBN 13: 9783319575346
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who willprovide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians.