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Short-Term Bioassays in the Analysis of Complex Environmental Mixtures (volume II)
Symposium on the Application of Short-Term Bioassays in the Fractionat;Waters, Michael
Sprache: Englisch
Verlag: Plenum Pub Corp, New York, New York, U.S.A., 1981
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Short-Term Bioassays In the Analysis of Complex Environmental Mixtures, Pt. 2 (Environmental Science Research Ser., Vol. 22)
Waters, Michael D. (editor); Sandhu, Shahbeg S. (editor); Huisingh, Joellen L. (editor); Claxton, Larry (editor); Nesnow, Stephen (editor)
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Hardcover. Zustand: Good. . . . . 8vo, hardcover. No dj. Good condition. Non-circulating ex-lib copy w/ stamping to endpapers & text-block edges, spine label removed, leaving outline; spine & cover edge moderately sunned (spine lettering fully legible); interior bright, crisp & clean. ix, 693 p., illus. Proceedings of a Symposiu…m on Organ and Species Specificity in Chemical Carcinogenesis, held during March 1981, in Raleigh, North Carolina.
Organ and Species Specificity in Chemical Carcinogenesis (Basic Life Scienc Es, Volume 24)
Langenbach, Robert, Stephen Nesnow, And Jerry M. Rice, Editors
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Short-Term Bioassays in the Analysis of Complex Environmental Mixtures II
Michael Waters, Stephen Nesnow, Joellen L. Huisingh, Shahbeg S. Sandhu, Larry Claxton
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Contained in this volume are the proceedings of the international conference on the 'Genetic Toxicology of Complex Mixtures,' held from July 4-7, 1989, in Washington, DC. This meeting was a satellite of the 'Fifth International Conference on Environm…ental Mutagens' and the seventh in a biennial series of conferences on 'Short-term Bioassays in the Analysis of Complex Environmental Mixtures. ' Our central objective in calling together key researchers from around the world was to extend our knowledge of the application of the methods of genetic toxicology and analytical chemistry in the evaluation of chemical mixtures as they exist in the environment. This conference emphasized the study of genotoxicants in air and water, and the assessment of human exposure and cancer risk. The latest strategies and methodologies for biomonitoring of genotoxicants (including transformation products) were described in the context of the ambient environment. Source character ization and source apportionment were discussed as an aid to understand ing the origin and relative contribution of various kinds of complex mix tures to the ambient environment. Similarly, investigations of genotoxi cants found in the indoor environment (sidestream cigarette smoke) and in drinking water (chlorohydroxyfuranones) were given special attention in terms of their potential health impacts. New molecular techniques were described to enable more precise quantitation of internal dose and dose to-target tissues. The emphasis of presentations on exposures/effects assessment was on integrated quantitative evaluation of human exposure and potential health effects.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - More than one hundred short-term bioassays are now available for detecting the toxicity, mutagenicity, and potential carcinogenicity of chemicals. These bioassays were developed and validated with individual compounds, and their principal application… was perceived to be in evaluating the health hazard of such materials. However, man is rarely exposed to single chemicals; his exposure to hazardous chemicals is more commonly a multifactorial phenomenon. Although chemical analysis can be used to detect known hazardous compounds, it would be a staggering and expensive task to analyze large numbers of samples for all known or suspected hazardous constituents. Furthermore, the biological activity of a complex mixture cannot be reliably predicted from knowledge of its components. On the other hand, bioassays alone cannot tell us which components of complex mixtures are responsible for the biological activity detected. Thus, cost effectiveness and technical feasibility dictate stepwise and perhaps iterative application -of both chemical and biological methods in evaluating the health effects of complex environmental mixtures. Through the coupling of reliable biological detection systems with methods of chemical fractionation and analysis, it is frequently possible to isolate the individual chemical species that show biological activity. Initially, complex mixtures may be separated and bioassayed in carefully defined chemical fractions. The results of such short-term screening bioassays then may be used td guide the course of further fractionation and to determine the need for more stringent and comprehensive biological testing.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Contained in this volume are the proceedings of the international conference on the 'Genetic Toxicology of Complex Mixtures,' held from July 4-7, 1989, in Washington, DC. This meeting was a satellite of the 'Fifth International Confer…ence on Environmental Mutagens' and the seventh in a biennial series of conferences on 'Short-term Bioassays in the Analysis of Complex Environmental Mixtures. ' Our central objective in calling together key researchers from around the world was to extend our knowledge of the application of the methods of genetic toxicology and analytical chemistry in the evaluation of chemical mixtures as they exist in the environment. This conference emphasized the study of genotoxicants in air and water, and the assessment of human exposure and cancer risk. The latest strategies and methodologies for biomonitoring of genotoxicants (including transformation products) were described in the context of the ambient environment. Source character ization and source apportionment were discussed as an aid to understand ing the origin and relative contribution of various kinds of complex mix tures to the ambient environment. Similarly, investigations of genotoxi cants found in the indoor environment (sidestream cigarette smoke) and in drinking water (chlorohydroxyfuranones) were given special attention in terms of their potential health impacts. New molecular techniques were described to enable more precise quantitation of internal dose and dose to-target tissues. The emphasis of presentations on exposures/effects assessment was on integrated quantitative evaluation of human exposure and potential health effects. 388 pp. Englisch.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -More than one hundred short-term bioassays are now available for detecting the toxicity, mutagenicity, and potential carcinogenicity of chemicals. These bioassays were developed and validated with individual compounds, and their princ…ipal application was perceived to be in evaluating the health hazard of such materials. However, man is rarely exposed to single chemicals; his exposure to hazardous chemicals is more commonly a multifactorial phenomenon. Although chemical analysis can be used to detect known hazardous compounds, it would be a staggering and expensive task to analyze large numbers of samples for all known or suspected hazardous constituents. Furthermore, the biological activity of a complex mixture cannot be reliably predicted from knowledge of its components. On the other hand, bioassays alone cannot tell us which components of complex mixtures are responsible for the biological activity detected. Thus, cost effectiveness and technical feasibility dictate stepwise and perhaps iterative application -of both chemical and biological methods in evaluating the health effects of complex environmental mixtures. Through the coupling of reliable biological detection systems with methods of chemical fractionation and analysis, it is frequently possible to isolate the individual chemical species that show biological activity. Initially, complex mixtures may be separated and bioassayed in carefully defined chemical fractions. The results of such short-term screening bioassays then may be used td guide the course of further fractionation and to determine the need for more stringent and comprehensive biological testing. 544 pp. Englisch.
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Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III
Nesnow Stephen Chernoff Neil Claxton Larry Lewtas Joellen Sandhu Shahbeg S. Waters Michael D.
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Genetic Toxicology of Complex Mixtures
Waters, Michael D.|Daniel, F.Bernhard|Lewtas, Joellen|Moore, Martha M.|Nesnow, Stephen
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of a symposium held in Washington, DC, July 4-7, 1989 Contained in this volume are the proceedings of the international conference on the Genetic Toxicology of Complex Mixtures, held from July 4-7, 1989, in…Washington, DC. This meeting wa.
Short-Term Bioassays in the Analysis of Complex Environmental Mixtures II
Waters, Michael|Nesnow, Stephen|Huisingh, Joellen L.|Sandhu, Shahbeg S.|Claxton, Larry
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. More than one hundred short-term bioassays are now available for detecting the toxicity, mutagenicity, and potential carcinogenicity of chemicals. These bioassays were developed and validated with individual compounds,…and their principal application was pe.
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Contained in this volume are the proceedings of the international conference on the 'Genetic Toxicology of Complex Mixtures,' held from July 4-7, 1989, in Washington, DC. This meeting was a satellite of the 'Fifth International Conference… on Environmental Mutagens' and the seventh in a biennial series of conferences on 'Short-term Bioassays in the Analysis of Complex Environmental Mixtures. ' Our central objective in calling together key researchers from around the world was to extend our knowledge of the application of the methods of genetic toxicology and analytical chemistry in the evaluation of chemical mixtures as they exist in the environment. This conference emphasized the study of genotoxicants in air and water, and the assessment of human exposure and cancer risk. The latest strategies and methodologies for biomonitoring of genotoxicants (including transformation products) were described in the context of the ambient environment. Source character ization and source apportionment were discussed as an aid to understand ing the origin and relative contribution of various kinds of complex mix tures to the ambient environment. Similarly, investigations of genotoxi cants found in the indoor environment (sidestream cigarette smoke) and in drinking water (chlorohydroxyfuranones) were given special attention in terms of their potential health impacts. New molecular techniques were described to enable more precise quantitation of internal dose and dose to-target tissues. The emphasis of presentations on exposures/effects assessment was on integrated quantitative evaluation of human exposure and potential health effects.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 388 pp. Englisch.
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -More than one hundred short-term bioassays are now available for detecting the toxicity, mutagenicity, and potential carcinogenicity of chemicals. These bioassays were developed and validated with individual compounds, and their principal… application was perceived to be in evaluating the health hazard of such materials. However, man is rarely exposed to single chemicals; his exposure to hazardous chemicals is more commonly a multifactorial phenomenon. Although chemical analysis can be used to detect known hazardous compounds, it would be a staggering and expensive task to analyze large numbers of samples for all known or suspected hazardous constituents. Furthermore, the biological activity of a complex mixture cannot be reliably predicted from knowledge of its components. On the other hand, bioassays alone cannot tell us which components of complex mixtures are responsible for the biological activity detected. Thus, cost effectiveness and technical feasibility dictate stepwise and perhaps iterative application -of both chemical and biological methods in evaluating the health effects of complex environmental mixtures. Through the coupling of reliable biological detection systems with methods of chemical fractionation and analysis, it is frequently possible to isolate the individual chemical species that show biological activity. Initially, complex mixtures may be separated and bioassayed in carefully defined chemical fractions. The results of such short-term screening bioassays then may be used td guide the course of further fractionation and to determine the need for more stringent and comprehensive biological testing.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 544 pp. Englisch.
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Taschenbuch. Zustand: Neu. Short-Term Bioassays in the Analysis of Complex Environmental Mixtures II | Michael Waters (u. a.) | Taschenbuch | 524 S. | Englisch | 2012 | Springer US | EAN 9781468441239 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[…dot]com | Anbieter: preigu Print on Demand.
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Taschenbuch. Zustand: Neu. Genetic Toxicology of Complex Mixtures | Michael D. Waters (u. a.) | Taschenbuch | 384 S. | Englisch | 2012 | Springer | EAN 9781468458527 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on… Demand.
