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Taschenbuch. Zustand: Neu. Evaluation of CNS potential of Hedychium spicatum | Rhizome Extract | Versha Parcha (u. a.) | Taschenbuch | 76 S. | Englisch | 2012 | LAP LAMBERT Academic Publishing | EAN 9783659227196 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. …

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The medicinal value of different species of Hedychium spicatum has been known for a long time. There are various reports of this plant indicating tranquilizing, analgesic, anti-inflammatory, pediculicidal, antimicrobial, antioxidant, antifungal, antimalarial, cytotoxic, hypocholesterolemic & anthelmintic activity. No information about it s CNS potential is been observed in the literature. In the present study rhizomes of Hedychium spicatum were extracted with ethanol. Then total ethanolic extract was fractionated with pet ether, chloroform, ethyl acetate and butanol. All the fractions were qualitatively analyzed for their phytoconstituents & for CNS activity based on locomotor activity of Wister rats using actophotometer. The results strongly favour the significant antidepressant activity of the ethyl acetate fraction and significant CNS stimulant activity of butanol fraction of Hedychium spicatum rhizomes. It was also observed that the ethyl acetate fraction was rich in alkaloids & carbohydrates & butanol extract was rich in carbohydrates. The TLC study of the ethyl acetate fraction also supports the presence of 4 & butanol fraction supports the presence of 7 major compounds. 76 pp. Englisch. …

Zustand: New. Print on Demand pp. 84 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.

Zustand: New. PRINT ON DEMAND pp. 84.

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: KAUSHIK VICHITRADr. Vichitra kaushik has completed his B.Pharm from HNBGU, Srinagar, M.Pharm (Pharmacognosy) from BIT, Ranchi with GATE scholarship & PhD (Pharmacy) from GBTU, Lucknow. He has 1 national & 4 international publicati.…

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: KAUSHIK VICHITRADr. Vichitra Kaushik presently working as Associate Prof. in MM College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India. Dr. Versha Parcha as Prof. (Natural Products) in DOPS, SBSPGI, Balaw. …

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: KAUSHIK VICHITRADr. Vichitra Kaushik currently working as Associate Prof in M.M.College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India, Dr. R L Khosa, formerly Prof and HOD Pharmacy, IT, BHU, India, Curr.…

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: KAUSHIK VICHITRADr. Vichitra Kaushik currently working as Associate Prof (Pharmacognosy) & Dr. Versha Parcha as Prof (Natural Products) in Dept. of Pharm. Sciences, S.B.S.P.G.I., Balawala, Dehradun, Uttarakhand, India. Dr. R L Khosa.. …

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. &Uumlber den AutorrnrnDr. Vichitra Kaushik currently working as Associate Prof in M.M.College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India, Dr. R L Khosa, formerly Prof and HOD Pharmacy, IT, BHU, India, Currently. …

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Parcha VershaDr. Versha Parcha currently working as HOD chemistry, S.B.S.P.G. Inst. of Biomed. Scs. & Research, Balawala, Dehradun, Uttarakhand (India). Dr. Vichitra Kaushik as Associate Prof. & HOD Pharmacognosy, MM College of Pharm.…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A novel Pentamethoxy Flavonol 'Cordiofolinol' (P3) has been isolated from anti-inflammatory activity guided fractionation of methanol extract of Haldina cordifolia stem Bark with a gradient of methanol in chloroform. Further P3 was screened for anti-inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P3 has showed significant reduction in inflammation caused by carrageenan (P0.01) and dextran (P0.05). Hence P3 can be considered as the principle component responsable for the anti-inflammatory activity for Haldina cordifolia bark. The characterization of P3 was done by spectral studies like IR, 1H-NMR, 13C-NMR & mass spectroscopy. On the basis of spectral studies the structure of P3 has been elucidated as 5, 7, 3', 4', 5' Pentamethoxy Flavonol. This is a novel Flavonol isolated from the bark of H. cordifolia for the first time and given a trival name Cordiofolinol.…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A novel bicyclic lactone 'Michelianone' (P4) has been isolated from anti-inflammatory activity guided fractionation of chloroform extract of Michelia oblonga leaf with a gradient of ethyl acetate in petroleum ether. Further P4 was screened for anti- inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P4 has showed significant reduction in inflammation caused by carrageenan (P<0.01) and dextran (P<0.05). Hence P4 can be considered as the principle component responsible for the anti- inflammatory activity for Michelia oblonga leaf. The characterization of P4 was done by spectral studies like IR, 1H-NMR, 13C-NMR & Mass Spectroscopy. On the basis of spectral studies the structure of P4 has been elucidated as bicyclic lactone. This is a novel bicyclic lactone isolated from the leaf of M. oblonga for the first time and given a trivial name Michelianone.…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Une nouvelle lactone bicyclique, la 'Michelianone' (P4), a été isolée à partir du fractionnement guidé par l'activité anti-inflammatoire de l'extrait de chloroforme de la feuille de Michelia oblonga avec un gradient d'acétate d'éthyle dans l'éther de pétrole. D'autres P4 ont été analysés pour leur activité anti-inflammatoire sur des modèles d'inflammation induite par la carraghénine et le dextran chez le rat à la dose de 50 mg/kg de poids corporel. Le traitement de rats inflammés avec du P4 a montré une réduction significative de l'inflammation causée par le carraghénane (P<0,01) et le dextrane (P<0,05). Le P4 peut donc être considéré comme le principal composant responsable de l'activité anti-inflammatoire de la feuille de Michelia oblonga. La caractérisation du P4 a été faite par des études spectrales comme l'IR, la RMN 1H, la RMN 13C et la spectroscopie de masse. Sur la base d'études spectrales, la structure du P4 a été élucidée en tant que lactone bicyclique. Il s'agit d'une nouvelle lactone bicyclique isolée de la feuille de M. oblonga pour la première fois et à laquelle on a donné un nom trivial de Michelianone.…

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. &Uumlber den AutorrnrnDr. Vichitra Kaushik currently working as Associate Prof in M.M.College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India, Dr. R L Khosa, formerly Prof and HOD Pharmacy, IT, BHU, India, Currently. …

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Z frakcjonowania ekstraktu chloroformu z li¿ci Michelia oblonga o gradiencie octanu etylu w eterze naftowym wyizolowano nowy dwucykliczny lakton 'Michelianone' (P4). Nast¿pnie P4 by¿ badany pod k¿tem aktywno¿ci przeciwzapalnej na modelu zapalenia wywo¿anego karagenem i dekstranem u szczurów w dawce 50 mg/kg masy ciäa. Leczenie szczurów zapalonych P4 wykazäo istotne zmniejszenie zapalenia wywo¿anego przez karagen (P<0,01) i dekstran (P<0,05). Dlatego te¿ P4 mo¿na uznä za g¿ówny sk¿adnik odpowiedzialny za dziäanie przeciwzapalne li¿cia Michelia oblonga. Charakterystyk¿ P4 wykonano za pomoc¿ badä spektralnych, takich jak IR, 1H-NMR, 13C-NMR i spektroskopii masowej. Na podstawie badä spektralnych struktura P4 zostäa wyjäniona jako dwucykliczny lakton. Jest to nowy dwucykliczny lakton wyizolowany z li¿cia M. oblonga po raz pierwszy i nazwany trywialn¿ nazw¿ Michelianone.…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Uma nova lactona bicíclica 'Michelianona' (P4) foi isolada da actividade anti-inflamatória guiada pelo fraccionamento do extracto de clorofórmio de folha de Michelia oblonga com um gradiente de acetato de etilo em éter de petróleo. Além disso, o P4 foi submetido a um rastreio da actividade anti-inflamatória na carragenina e no modelo de inflamação induzida por dextrano em ratos ao nível da dose de 50 mg/kg de peso corporal. O tratamento de ratos inflamados com P4 mostrou uma redução significativa da inflamação causada pela carragenina (P<0,01) e pelo dextrano (P<0,05). Assim, o P4 pode ser considerado como o principal componente responsável pela actividade anti-inflamatória da folha de Michelia oblonga. A caracterização de P4 foi feita por estudos espectrais como IR, 1H-NMR, 13C-NMR & Espectroscopia de Massa. Com base em estudos espectrais, a estrutura do P4 foi elucidada como lactona bicíclica. Trata-se de uma nova lactona bicíclica isolada da folha de M. oblonga pela primeira vez e que recebeu um nome trivial Michelianone.…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Un nuovo lattone ciclico 'Michelianone' (P4) è stato isolato dal frazionamento guidato da attività antinfiammatoria dell'estratto di cloroformio della foglia di Michelia oblonga con un gradiente di acetato di etile in etere di petrolio. Ulteriore P4 è stato sottoposto a screening per l'attività anti-infiammatoria su carragenina e destrano modello di infiammazione indotta da destrano nei ratti al livello di dose di 50 mg / kg di peso corporeo. Il trattamento dei ratti infiammati con P4 ha mostrato una significativa riduzione dell'infiammazione causata da carragenina (P<0,01) e destrano (P<0,05). Quindi il P4 può essere considerato come il principale componente responsabile dell'attività antinfiammatoria della foglia di Michelia oblonga. La caratterizzazione di P4 è stata fatta da studi spettrali come IR, 1H-NMR, 13C-NMR e spettroscopia di massa. Sulla base di studi spettrali la struttura di P4 è stata chiarita come lattone ciclico. Si tratta di un nuovo lattone ciclico isolato dalla foglia di M. oblonga per la prima volta e dato un nome banale Michelianone.…

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. &Uumlber den AutorrnrnDr. Vichitra Kaushik currently working as Associate Prof in M.M.College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India, Dr. R L Khosa, formerly Prof and HOD Pharmacy, IT, BHU, India, Currently. …

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. &Uumlber den AutorrnrnDr. Vichitra Kaushik currently working as Associate Prof in M.M.College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India, Dr. R L Khosa, formerly Prof and HOD Pharmacy, IT, BHU, India, Currently. …

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. &Uumlber den AutorrnrnDr. Vichitra Kaushik currently working as Associate Prof in M.M.College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India, Dr. R L Khosa, formerly Prof and HOD Pharmacy, IT, BHU, India, Currently. …

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Ein neuartiges bicyclisches Lacton Michelianone (P4) wurde durch entzuendungshemmende aktivitaetsgesteuerte Fraktionierung eines Chloroformextraktes aus Michelia oblonga-Blatt mit einem Gradienten von Ethylacetat in Petrolether isoliert. Darueber hinaus wurd.…