Ramon moliner e (10 Ergebnisse)
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Sprache: Englisch
Verlag: Springer, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
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Sprache: Englisch
Verlag: Springer-Verlag Berlin and Heidelberg GmbH and Co. KG, DE, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
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Paperback. Zustand: New. 1972 ed. The earliest studies on the regional distribution of acetylcholinesterase (AChE) within the central nervous system were based on the determination of the amount of CO liberated by homogenates of selected areas in the presence of an ester of 2 choline and a bicarbonate buffer. Using this biochemi…cal approach, Burgen and Chipman (1951) were able to establish that acetylcholinesterase is not evenly distributed within the central nervous system. They found that the cerebellum, the lateral geniculate body, and the striatum contained a high concentration of AChE. The high concentration of AChE in the striatum could be correlated with a higher rate of acetylcholine synthesis. However, this was not the case for the cerebellum, where acetylcholine synthesis was very low. Other in vitro studies have been aimed at establishing the regional distribution of the other two components of the cholinergic system, cholinacetylase (ChA) and acetylcholine (ACh).An equally asymetrical distribution for these substances has been established in vitro (MacIntosh, 1941; Feldberg and Mann, 1946; Feldberg and V ogt, 1948; MacIntosh and Oborin, 1953; Quastel, 1962; Mitchell, 1963; Krnjevic and Phillis, 1963; Aprison et al. , 1964; McLennan, 1964; Cohen, 1956). The in vitro determination of acetylcholinesterase (Koelle, 1950; Burgen and Chipman, 1951; Giacobini, 1959; Bennett et al. , 1966; Fahn and Cote, 1968; Miller et al. , 1969) presents the advan- tage of permitting the use of a substrate like ACh which is a normally occurring ester of choline so that the establishment of enzyme specificity is less questionable.
Sprache: Englisch
Verlag: Springer, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
- Softcover
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Paperback. Zustand: Brand New. 1972 edition. 56 pages. 9.60x6.69x0.13 inches. In Stock.
Sprache: Englisch
Verlag: Springer, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
- Softcover
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The earliest studies on the regional distribution of acetylcholinesterase (AChE) within the central nervous system were based on the determination of the amount of CO liberated by homogenates of selected areas in the presence of an ester of 2 choline… and a bicarbonate buffer. Using this biochemical approach, Burgen and Chipman (1951) were able to establish that acetylcholinesterase is not evenly distributed within the central nervous system. They found that the cerebellum, the lateral geniculate body, and the striatum contained a high concentration of AChE. The high concentration of AChE in the striatum could be correlated with a higher rate of acetylcholine synthesis. However, this was not the case for the cerebellum, where acetylcholine synthesis was very low. Other in vitro studies have been aimed at establishing the regional distribution of the other two components of the cholinergic system, cholinacetylase (ChA) and acetylcholine (ACh). An equally asymetrical distribution for these substances has been established in vitro (MacIntosh, 1941 ; Feldberg and Mann, 1946; Feldberg and V ogt, 1948; MacIntosh and Oborin, 1953; Quastel, 1962; Mitchell, 1963; Krnjevic and Phillis, 1963; Aprison et al. , 1964; McLennan, 1964; Cohen, 1956). The in vitro determination of acetylcholinesterase (Koelle, 1950; Burgen and Chipman, 1951; Giacobini, 1959; Bennett et al. , 1966; Fahn and Cote, 1968; Miller et al. , 1969) presents the advan tage of permitting the use of a substrate like ACh which is a normally occurring ester of choline so that the establishment of enzyme specificity is less questionable.
Sprache: Englisch
Verlag: Springer-Verlag Berlin and Heidelberg GmbH and Co. KG, DE, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
- Softcover
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Paperback. Zustand: New. 1972 ed. The earliest studies on the regional distribution of acetylcholinesterase (AChE) within the central nervous system were based on the determination of the amount of CO liberated by homogenates of selected areas in the presence of an ester of 2 choline and a bicarbonate buffer. Using this biochemi…cal approach, Burgen and Chipman (1951) were able to establish that acetylcholinesterase is not evenly distributed within the central nervous system. They found that the cerebellum, the lateral geniculate body, and the striatum contained a high concentration of AChE. The high concentration of AChE in the striatum could be correlated with a higher rate of acetylcholine synthesis. However, this was not the case for the cerebellum, where acetylcholine synthesis was very low. Other in vitro studies have been aimed at establishing the regional distribution of the other two components of the cholinergic system, cholinacetylase (ChA) and acetylcholine (ACh).An equally asymetrical distribution for these substances has been established in vitro (MacIntosh, 1941; Feldberg and Mann, 1946; Feldberg and V ogt, 1948; MacIntosh and Oborin, 1953; Quastel, 1962; Mitchell, 1963; Krnjevic and Phillis, 1963; Aprison et al. , 1964; McLennan, 1964; Cohen, 1956). The in vitro determination of acetylcholinesterase (Koelle, 1950; Burgen and Chipman, 1951; Giacobini, 1959; Bennett et al. , 1966; Fahn and Cote, 1968; Miller et al. , 1969) presents the advan- tage of permitting the use of a substrate like ACh which is a normally occurring ester of choline so that the establishment of enzyme specificity is less questionable.
Sprache: Englisch
Verlag: Springer, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
- Softcover
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Paperback. Zustand: Very Good. Dust Jacket may NOT BE INCLUDED.CDs may be missing. SHIPS FROM MULTIPLE LOCATIONS. book.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, Springer Berlin Heidelberg Dez 1972, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The earliest studies on the regional distribution of acetylcholinesterase (AChE) within the central nervous system were based on the determination of the amount of CO liberated by homogenates of selected areas in the presence of an es…ter of 2 choline and a bicarbonate buffer. Using this biochemical approach, Burgen and Chipman (1951) were able to establish that acetylcholinesterase is not evenly distributed within the central nervous system. They found that the cerebellum, the lateral geniculate body, and the striatum contained a high concentration of AChE. The high concentration of AChE in the striatum could be correlated with a higher rate of acetylcholine synthesis. However, this was not the case for the cerebellum, where acetylcholine synthesis was very low. Other in vitro studies have been aimed at establishing the regional distribution of the other two components of the cholinergic system, cholinacetylase (ChA) and acetylcholine (ACh). An equally asymetrical distribution for these substances has been established in vitro (MacIntosh, 1941 ; Feldberg and Mann, 1946; Feldberg and V ogt, 1948; MacIntosh and Oborin, 1953; Quastel, 1962; Mitchell, 1963; Krnjevic and Phillis, 1963; Aprison et al. , 1964; McLennan, 1964; Cohen, 1956). The in vitro determination of acetylcholinesterase (Koelle, 1950; Burgen and Chipman, 1951; Giacobini, 1959; Bennett et al. , 1966; Fahn and Cote, 1968; Miller et al. , 1969) presents the advan tage of permitting the use of a substrate like ACh which is a normally occurring ester of choline so that the establishment of enzyme specificity is less questionable. 56 pp. Englisch.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Materials and Methods.- Observations.- Motoneuronal Centers and Neighbor Regions.- Sensory Relay Centers and Neighbor Regions.- Specific Precerebellar Centers.- Other Well Outlined Centers.- Diffuse Reticular and Tegmen…tal Regions.- Midline and Paramedian N.
Sprache: Englisch
Verlag: Springer, Springer Dez 1972, 1972
Serie: Buch 45 von 173 - Advances in Anatomy, Embryology and Cell Biology
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Materials and Methods.- Observations.- Motoneuronal Centers and Neighbor Regions.- Sensory Relay Centers and Neighbor Regions.- Specific Precerebellar Centers.- Other Well Outlined Centers.- Diffuse Reticular and Tegmental Regions.- Midli…ne and Paramedian Nuclei of the Brain Stem.- Subependymal Regions.- Discussion.- 1. Cholinergic Transmission in the Nervous System.- 2. The Significance of a Positive AThChE Stain.- 3. The Distribution of Acetylthiocholinesterase in the Brain Stem.- Summary.- Abbreviations.- References.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 56 pp. Englisch.
