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Taschenbuch. Zustand: Neu. Mitochondria in Obesity and Type 2 Diabetes | Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases | Beatrice Morio (u. a.) | Taschenbuch | Englisch | 2019 | Elsevier Science | EAN 9780128117521 | Verantwortliche Person für die EU: Elsevier B.V., Radarweg 29, 1043 NX AMSTERDAM, NIEDERLANDE, productsafety[at]elsevier[dot]com | Anbieter: preigu. …

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Taschenbuch. Zustand: Neu. Bioenergetics of the Cell: Quantitative Aspects | Valdur A. Saks (u. a.) | Taschenbuch | vi | Englisch | 2012 | Springer | EAN 9781461375876 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Zustand: Gut. Zustand: Gut | Seiten: 472 | Sprache: Englisch | Produktart: Bücher | This volume continues the discussion of the problems of in vivo and in vitro. The recently solved X-ray structure of the mitochondrial creatine kinase and its molecular biology cellular bioenergetics - the tradition we started in 1994 by publication of the focused issue of Molecular and Cellular are analyzed with respect to its molecular physiology and Biochemistry, volume 133/134 and a book 'Cellular Bio­ functional coupling to the adenine nucleotide translocase, as energetics: role of coupled creatine kinases' edited by V. Saks well as its participation, together with the adenylate kinase and R. Ventura-Clapier and published by Kluwer Publishers, system, in intracellular energy transfer. The results of the Dordrecht -Boston. In the present volume, use of quantitative studies of creatine kinase deficient transgenic mice are methods of studies of organized metabolic systems, such as summarized and analyzed by using mathematical models of mathematical modeling and Metabolic Control Analysis, for the compartmentalized energy transfer, thus combining two investigation of the problems of bioenergetics of the cell is powerful new methods of the research. All these results, described together with presentation of new experimental together with the physiological and NMR data on the cardiac results. The following central problems of the cellular bio­ metabolic and mitochondrial responses to work-load changes energetics are the focus of the discussions: the mechanisms concord to the concept of metabolic networks of energy of regulation of oxidative phosphorylation in the cells in vivo transfer and feedback regulation.…

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Taschenbuch. Zustand: Neu. Neuware - Tout jeune enfant, Jean saisit sa disgrâce, avec effroi, dans le regard, dans les attitudes et dans l'expression mal contenue, de la répugnance des adultes: l'extraordinaire laideur d'un visage dépourvu du moindre attrait. Frank, quant à lui, voit son enfance enchantée effacée par un terrible arrachement aux siens. Malgré ces oukases, il leur faut, à tous les deux, commencer une autre vie afin de simplement survivre ou de trouver les voies si improbables d'un accomplissement magique. Leur rencontre éphémère mais fusionnelle, révélatrice et déterminante, changera leur destinée jusque-là chaotique. Ce que l'on apprend d'eux provient d'un récit polyphonique, parcellaire, nourri de lumière et de silence, qui trace et retrace les trames incertaines de leurs vies que l'on peut imaginer parfois s'apaiser où tout a commencé, à l'ombre douce des jupes ténébreuses des veuves.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume continues the discussion of the problems of in vivo and in vitro. The recently solved X-ray structure of the mitochondrial creatine kinase and its molecular biology cellular bioenergetics - the tradition we started in 1994 by publication of the focused issue of Molecular and Cellular are analyzed with respect to its molecular physiology and Biochemistry, volume 133/134 and a book 'Cellular Bio functional coupling to the adenine nucleotide translocase, as energetics: role of coupled creatine kinases' edited by V. Saks well as its participation, together with the adenylate kinase and R. Ventura-Clapier and published by Kluwer Publishers, system, in intracellular energy transfer. The results of the Dordrecht -Boston. In the present volume, use of quantitative studies of creatine kinase deficient transgenic mice are methods of studies of organized metabolic systems, such as summarized and analyzed by using mathematical models of mathematical modeling and Metabolic Control Analysis, for the compartmentalized energy transfer, thus combining two investigation of the problems of bioenergetics of the cell is powerful new methods of the research. All these results, described together with presentation of new experimental together with the physiological and NMR data on the cardiac results. The following central problems of the cellular bio metabolic and mitochondrial responses to work-load changes energetics are the focus of the discussions: the mechanisms concord to the concept of metabolic networks of energy of regulation of oxidative phosphorylation in the cells in vivo transfer and feedback regulation.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book describes the use of quantitative methods in studies in organized metabolic systems, such as mathematical modeling and Metabolic Control Analysis, for investigation of the problems of bioenergetics of the cell and also presents new experimental results. The following central problems of cellular bioenergetics are the focus of the discussions: the mechanisms of regulation of oxidative phosphorylation in cells in vivo in health and disease, the influence of fine intracellular structural organization on mitochondrial function, the intracellular networks of energy transfer and metabolic feedback signaling, the role of mitochondria in intracellular calcium cycling, and changes in mitochondrial membrane systems and cellular energetics under pathological conditions. Systematic studies from many laboratories presented in this volume convincingly show that many mitochondrial properties, including affinities for mitochondrial creatine kinase and its molecular biology are related to its molecular physiology and functional coupling to adenine nucleotide translocase, as well as its participation, together with the adenylate kinase system, in intracellular energy transfer. The results of the studies of creatine kinase-deficient transgenic mice are summarized and analyzed using mathematical models of the compartmentalized energy transfer, thus combining two powerful new research methods. All these results, together with physiological and NMR data on the cardiac metabolic and mitochondrial responses to workload changes, confirm the concept of metabolic networks of energy transfer and feedback regulation. The papers, mostly review articles, are written by the leading experts in the field who analyze their experience of research and give insights into the future development of this increasingly important area of biological sciences.…

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