Robert n eisenman (35 Ergebnisse)
- Hardcover
Anbieter: ThriftBooks-Atlanta, AUSTELL, GA, USAThriftBooks-Atlanta
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Gebraucht - Gut
EUR 14,43
Versand nach gratisVersand innerhalb von USAAnzahl: 1 verfügbar
Hardcover. Zustand: Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.
- Softcover
Anbieter: Basi6 International, Irving, TX, USABasi6 International
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 54,59
Versand nach gratisVersand innerhalb von USAAnzahl: 3 verfügbar
Zustand: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press CSHL Press 2014
- Hardcover
Anbieter: Books Puddle, New York, NY, USABooks Puddle
Verkäufer/-in kontaktierenVerkäufer/-in mit 4 SternenZustand: Neu
EUR 135,61
EUR 3,48 VersandVersand innerhalb von USAAnzahl: 4 verfügbar
Zustand: New. pp. 400 Index.
- Hardcover
Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 142,88
EUR 2,30 VersandVersand innerhalb von USAAnzahl: 1 verfügbar
Zustand: New.
- Hardcover
Anbieter: Majestic Books, Hounslow, , Vereinigtes KönigreichMajestic Books
Verkäufer/-in kontaktierenVerkäufer/-in mit 4 SternenZustand: Neu
EUR 137,54
EUR 7,50 VersandVersand von Vereinigtes Königreich nach USAAnzahl: 4 verfügbar
Zustand: New. pp. 400 Illus.
- Hardcover
Anbieter: Mispah books, Redhill, SURRE, Vereinigtes KönigreichMispah books
Verkäufer/-in kontaktierenVerkäufer/-in mit 4 SternenZustand: Gebraucht - Wie neu
EUR 115,21
EUR 28,83 VersandVersand von Vereinigtes Königreich nach USAAnzahl: 1 verfügbar
Hardcover. Zustand: Like New. Like New. book.
- Hardcover
Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Gebraucht - Wie neu
EUR 145,62
EUR 2,30 VersandVersand innerhalb von USAAnzahl: 1 verfügbar
Zustand: As New. Unread book in perfect condition.
- Hardcover
Anbieter: Biblios, frankfurt am main, HESSE, DeutschlandBiblios
Verkäufer/-in kontaktierenVerkäufer/-in mit 4 SternenZustand: Neu
EUR 139,23
EUR 9,95 VersandVersand von Deutschland nach USAAnzahl: 4 verfügbar
Zustand: New. pp. 400.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes KönigreichRia Christie Collections
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 163,72
EUR 13,81 VersandVersand von Vereinigtes Königreich nach USAAnzahl: Mehr als 20 verfügbar
Zustand: New. In.
Sprache: Englisch
Verlag: Springer 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes KönigreichRia Christie Collections
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 163,72
EUR 13,81 VersandVersand von Vereinigtes Königreich nach USAAnzahl: Mehr als 20 verfügbar
Zustand: New. In.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 180,05
EUR 2,30 VersandVersand innerhalb von USAAnzahl: 15 verfügbar
Zustand: New.
Sprache: Englisch
Verlag: Springer 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 180,48
EUR 2,30 VersandVersand innerhalb von USAAnzahl: 15 verfügbar
Zustand: New.
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press 2014
- Hardcover
Anbieter: Books in my Basket, New Delhi, , IndienBooks in my Basket
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 165,92
EUR 20,00 VersandVersand von Indien nach USAAnzahl: 1 verfügbar
Hardcover. Zustand: New. ISBN:9781621820086.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
Anbieter: moluna, Greven, , Deutschlandmoluna
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 136,16
EUR 48,99 VersandVersand von Deutschland nach USAAnzahl: Mehr als 20 verfügbar
Zustand: New.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: moluna, Greven, , Deutschlandmoluna
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 136,16
EUR 48,99 VersandVersand von Deutschland nach USAAnzahl: Mehr als 20 verfügbar
Zustand: New.
Weitere BilderSprache: Englisch
Verlag: Springer 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
Anbieter: preigu, Osnabrück, Deutschlandpreigu
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 140,00
EUR 70,00 VersandVersand von Deutschland nach USAAnzahl: 5 verfügbar
Taschenbuch. Zustand: Neu. The Myc/Max/Mad Transcription Factor Network | Robert N. Eisenman | Taschenbuch | Current Topics in Microbiology and Immunology | vii | Englisch | 2014 | Springer | EAN 9783642421419 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]…springer[dot]com | Anbieter: preigu.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: Books Puddle, New York, NY, USABooks Puddle
Verkäufer/-in kontaktierenVerkäufer/-in mit 4 SternenZustand: Neu
EUR 214,72
EUR 3,48 VersandVersand innerhalb von USAAnzahl: 4 verfügbar
Zustand: New. pp. xii + 284 1st Edition.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: Buchpark, Trebbin, , DeutschlandBuchpark
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Gebraucht - Gut
EUR 123,56
EUR 105,00 VersandVersand von Deutschland nach USAAnzahl: 1 verfügbar
Zustand: Gut. Zustand: Gut | Seiten: 300 | Sprache: Englisch | Produktart: Bücher | Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the ¿big picture¿ and excessive zeal in pursuit of a single pixel might seem to bo…rder on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.
Sprache: Englisch
Verlag: Springer 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 168,73
EUR 62,26 VersandVersand von Deutschland nach USAAnzahl: 1 verfügbar
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the 'big picture' and excessive zeal in pursuit of a single pixel might seem to border… on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 168,73
EUR 63,36 VersandVersand von Deutschland nach USAAnzahl: 1 verfügbar
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the 'big picture' and excessive zeal in pursuit of a single pixel might seem to border on an…obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: Buchpark, Trebbin, , DeutschlandBuchpark
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Gebraucht - Sehr gut
EUR 127,27
EUR 105,00 VersandVersand von Deutschland nach USAAnzahl: 1 verfügbar
Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 300 | Sprache: Englisch | Produktart: Bücher | Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the ¿big picture¿ and excessive zeal in pursuit of a single pixel might…seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.
Sprache: Englisch
Verlag: Springer Verlag 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: Revaluation Books, Exeter, , Vereinigtes KönigreichRevaluation Books
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 236,61
EUR 14,41 VersandVersand von Vereinigtes Königreich nach USAAnzahl: 2 verfügbar
Hardcover. Zustand: Brand New. 1st edition. 282 pages. 9.00x6.00x0.50 inches. In Stock.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: Mispah books, Redhill, SURRE, Vereinigtes KönigreichMispah books
Verkäufer/-in kontaktierenVerkäufer/-in mit 4 SternenZustand: Gebraucht - Wie neu
EUR 242,30
EUR 28,83 VersandVersand von Vereinigtes Königreich nach USAAnzahl: 1 verfügbar
Hardcover. Zustand: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Gebraucht - Wie neu
EUR 276,22
EUR 2,30 VersandVersand innerhalb von USAAnzahl: 15 verfügbar
Zustand: As New. Unread book in perfect condition.
Sprache: Englisch
Verlag: Springer 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
Anbieter: Mispah books, Redhill, SURRE, Vereinigtes KönigreichMispah books
Verkäufer/-in kontaktierenVerkäufer/-in mit 4 SternenZustand: Gebraucht - Wie neu
EUR 245,86
EUR 28,83 VersandVersand von Vereinigtes Königreich nach USAAnzahl: 1 verfügbar
Paperback. Zustand: Like New. Like New. book.
Sprache: Englisch
Verlag: Springer 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
Anbieter: GreatBookPrices, Columbia, MD, USAGreatBookPrices
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Gebraucht - Wie neu
EUR 279,88
EUR 2,30 VersandVersand innerhalb von USAAnzahl: 15 verfügbar
Zustand: As New. Unread book in perfect condition.
Sprache: Englisch
Verlag: Springer 2006
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: BUCHSERVICE / ANTIQUARIAT Lars Lutzer, Wahlstedt, DeutschlandBUCHSERVICE / ANTIQUARIAT Lars Lutzer
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Gebraucht - Gut
EUR 369,90
EUR 39,95 VersandVersand von Deutschland nach USAAnzahl: 1 verfügbar
Hardcover. Zustand: gut. 2006. The Myc/Max/Mad Transcription Factor Network In deutscher Sprache. pages.
Verlag: Frederick R. Weisman Art Foundation Santa Monica, CA 1990
- Softcover
Anbieter: Specific Object / David Platzker, New York, NY, USASpecific Object / David Platzker
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Gebraucht
EUR 314,15
EUR 7,41 VersandVersand innerhalb von USAAnzahl: 1 verfügbar
5 vol.: vol. 1: 57 pp. ; vol. 2: 58 pp. ; vol. 3: 42 pp.; vol. 4: 66 pp. ; vol. 5: 50 pp.; 5 vol.: 23.2 x 14.6 cm. (each); glue bound; black-and-white; edition size unknown; unsigned and unnumbered; offset-printed Volumes I-V of "Summary of a Workshop," a biannual series of symposiums on contemporary art sponsored by the Frederi…ck R. Weisman Foundation and held at various North American locations. Each symposium was accompanied by a catalogue which summarized the conversations that took place. Volume I: "The Relationship Between Art and Architecture," held in Santa Monica, CA, January 21-22, 1989. Participants included: Frank O. Gehry, Daniel Buren, Jean-Louis Cohen, Cesar Pelli, Donald Judd, Irving Lavin, Germano Celant, Henry N. Cobb, Christopher Knight, Mildred Friedman, John Chamberlain, Peter Eisenman, Robert Irwin, Michael Graves, Nancy Wexler, Henry T. Hopkins, and Michael Rotondi. Volume II: "Art + Architecture + Society," held in Toronto, Canada, July 22-23, 1989. Participants included: Henry T. Hopkins, Michael Rotondi, Diana Agrest, Lynda Benglis, Scott Burton, Adele Freedman, April Greiman, Alanna Heiss, Craig Hodgetts, Walter Hopps, Catherine Ingraham, Eric Owen Moss, Matt Mullican, Larry Richards, David Ross, Alexis Smith, and Leon Whiteson. Volume III, "Art Fairs : Plans and Process," held in Los Angeles, CA, December 5-6, 1989. Participants included: O. Kelley Anderson Jr., Brian Angel, Dr. Alberto Anfossi, Rosina Gómez Baeza, Dr. Emil Bammatter, Thomas P. Blackman, Van Deren Coke, Michelle De Angelus, Milton Esterow, Anita Kaegi, Claudio Bruni Sakraischik, Allan Schwartzman, Leif Ståhle, Tamara Thomas, Robert Thomson. Volume IV, "Conservation and Contemporary Art," held in Richmond, VA, June 4-5, 1990. Participants included: Henry T. Hopkins, Billie Milam, Albert Albano, James Bernstein, Sharon Blank, Victoria Blyth Hill, Tom Branchick, William Leischer, Carol Mancusi-Ungaro, Ross Merill, Roy De Forest, Tim Ebner, George Herms, Duane Hanson, Rotraut Klein-Moquay, Ida Kohlmeyer, Miriam Shapiro, Paul Brach, Zora Sweet Pinney, and Nora Halpern Brougher. Volume V, "Support for the Arts in Unsupportive Times," held in Los Angeles, CA, December 4-5, 1990. Participants included: Nora Halpern Brougher, Henry T. Hopkins, Cee Scott Brown, Marie Cieri, Pamela Clapp, Gary Garrels, Stanley Grinstein, David Ireland, Steven D. Lavine, Bella Lewitzky, Lisa Lyons, Anne MacDonald, Peter Norton, Max Palevsky, Claire Peeps, Dr. Thomas Reese, Joy Silverman, Tina Summerlin, Ella King Torrey, Joel Wachs, and Frederick R. Weisman. "Twice each year the Frederick R. Weisman Art Foundation conducts workshops dealing with issues of importance to those involved in the creation, exposition, collection, conservation and education of international contemporary art in all of its manifestations. These workshops bring together approximately eighteen experts in closed session for two days. The topic is determined by the Foundation but the direction that conversation takes is determined by the participants. There is no agenda. The workshops are taped, transcribed, edited, published in the present form and distributed to participants, interested parties, museums and libraries." -- Henry T. Hopkins, director. Very Good / Fine. Set of 5 volumes. Light rubbing and yellowing of cover edges and light yellowing of pages, otherwise Fine. Contents clean and unmarked.
Sprache: Englisch
Verlag: Springer 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
- Print-on-Demand
Anbieter: Brook Bookstore On Demand, Napoli, NA, ItalienBrook Bookstore On Demand
Verkäufer/-in kontaktierenVerkäufer/-in mit 3 SternenZustand: Neu
EUR 126,26
EUR 5,50 VersandVersand von Italien nach USAAnzahl: Mehr als 20 verfügbar
Zustand: new. Questo è un articolo print on demand.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg Sep 2014 2014
Serie: Current Topics in Microbiology and Immunology, Buch 18 von 322. Buch 18 von 322 - Current Topics in Microbiology and Immunology
- Softcover
- Print-on-Demand
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, , DeutschlandBuchWeltWeit Ludwig Meier e.K.
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 160,49
EUR 23,00 VersandVersand von Deutschland nach USAAnzahl: 2 verfügbar
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the 'big picture' and excessive zeal in pursuit of a single pixel migh…t seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms. 296 pp. Englisch.
