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Taschenbuch. Zustand: Neu. Masterworks for Clarinet and Piano | Schirmer Books | Taschenbuch | Buch | Englisch | 1986 | Schirmer G Books | EAN 9780793554058 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu.
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Taschenbuch. Zustand: Neu. The Nuclear Envelope | Methods and Protocols | Sue Shackleton (u. a.) | Taschenbuch | xiv | Englisch | 2018 | Springer US | EAN 9781493980680 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Sprache: Englisch
Verlag: Springer New York, Springer US, 2018
ISBN 10: 1493980688 ISBN 13: 9781493980680
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume provides a wide rangeof protocols used in studying the nuclear envelope, with special attention tothe experimental adjustments that may be required to successfully investigatethis complex organelle in cells from various organisms. The Nuclear Envelope:Methods and Protocols is divided into five sections: Part I - Nuclear EnvelopeIsolation; Part II - Nuclear Envelope Protein Interactions, Localization, andDynamics; Part III - Nuclear Envelope Interactions with the Cytoskeleton; PartIV - Nuclear Envelope-Chromatin Interactions; and Part V - Nucleo-CytoplasmicTransport. Many of the modifications discussed in this book have only beencirculated within laboratories that have conducted research in this field formany years. Written in the highly successful Methods in Molecular Biologyseries format, chapters include introductions to their respective topics, listsof the necessary materials and reagents, step-by-step, readily reproduciblelaboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting edge and thorough, The Nuclear Envelope: Methods and Protocols is a timely resource for researchers who have joined this dynamic and rapidly growing field.
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Zustand: New. Editor(s): Collas, Philippe; Shackleton, Sue; Schirmer, Eric C. Series: Methods in Molecular Biology. Num Pages: 537 pages, 26 black & white illustrations, 77 colour illustrations, 19 black & white tables, 73 colo. BIC Classification: PSF. Category: (G) General (US: Trade). Dimension: 188 x 264 x 35. Weight in Grams: 1182. . 2016. 1st ed. 2016. hardcover. . . . .
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Sprache: Englisch
Verlag: Springer New York, Springer US, 2016
ISBN 10: 1493935283 ISBN 13: 9781493935284
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume provides a wide rangeof protocols used in studying the nuclear envelope, with special attention tothe experimental adjustments that may be required to successfully investigatethis complex organelle in cells from various organisms. The Nuclear Envelope:Methods and Protocols is divided into five sections: Part I - Nuclear EnvelopeIsolation; Part II - Nuclear Envelope Protein Interactions, Localization, andDynamics; Part III - Nuclear Envelope Interactions with the Cytoskeleton; PartIV - Nuclear Envelope-Chromatin Interactions; and Part V - Nucleo-CytoplasmicTransport. Many of the modifications discussed in this book have only beencirculated within laboratories that have conducted research in this field formany years. Written in the highly successful Methods in Molecular Biologyseries format, chapters include introductions to their respective topics, listsof the necessary materials and reagents, step-by-step, readily reproduciblelaboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting edge and thorough, The Nuclear Envelope: Methods and Protocols is a timely resource for researchers who have joined this dynamic and rapidly growing field.
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Zustand: New. Editor(s): Collas, Philippe; Shackleton, Sue; Schirmer, Eric C. Series: Methods in Molecular Biology. Num Pages: 537 pages, 26 black & white illustrations, 77 colour illustrations, 19 black & white tables, 73 colo. BIC Classification: PSF. Category: (G) General (US: Trade). Dimension: 188 x 264 x 35. Weight in Grams: 1182. . 2016. 1st ed. 2016. hardcover. . . . . Books ship from the US and Ireland.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - 'Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer.'.
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