Sushil kumar kashaw (42 Ergebnisse)

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Zustand: New. Prof. Sushil K. Kashaw is a Professor and Raman Postdoctoral Fellow in the Department of Pharmaceutical Sciences at Dr. H.S. Gour University (A Central University) in Sagar, M.P. He has previously served as an academic and executive council member.

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Buch. Zustand: Neu. Neuware - This book comprehensively examines the applications of bioinformatics, computational chemistry, and artificial intelligence (AI) in the field of drug discovery and innovation. It provides foundational insights into bioinformatics and its applications, from cutting¿edge advancements in computational molecular phylogeny, structural bioinformatics, and metabolic computing to biological databases and data mining. In addition, this book covers critical aspects of data storage, retrieval, database structure, and annotation, providing a robust foundation for understanding the complexities in biological data management. It discusses computational protein modeling, molecular docking, pharmacophore modeling, quantitative structure-activity relationships, and innovative approaches for drug target identification. The chapters explore protein-ligand interactions, molecular dynamics simulations, density function theory, and the strategic endeavor of drug repurposing. Toward the end, this book discusses quality by design (QbD) in drug formulation, the transformative influence of AI and machine learning (ML) on drug discovery, computational tools for estimating pharmacokinetic parameters, and the conceptual underpinnings of computational genomics. This book will be useful for students, professionals, and researchers in the fields of pharmaceutical sciences, life sciences, pharmaceuticals, biotechnology, and computational biology.…

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Zustand: Gut. Zustand: Gut | Seiten: 52 | Sprache: Deutsch | Produktart: Bücher | Eine Wunde ist eine Verletzung der epithelialen Integrität der Haut, die auf eine Aggression oder ein Trauma zurückzuführen ist und durch eine Störung der Struktur und der Funktion des darunter liegenden normalen Gewebes hervorgerufen werden kann. Es wurde festgestellt, dass Hyperglykämie eine toxische Wirkung auf die Wundheilung durch die Bildung von fortgeschrittenen Glykierungsendprodukten hat, die die Bildung von Entzündungsmolekülen (TNF-, IL-1) fördern und die Kollagensynthese behindern. Mit dem hohen Glukosespiegel verändern sich auch die Zellmorphologie, die Proliferation nimmt ab, dem Granulationsgewebe mangelt es an Kollagen und die Differenzierung der Keratinozyten ist gestört. Hydrogele (HGs) sind Netzwerke aus dreidimensionalen Polymeren, die durch große Mengen eines Lösungsmittels aufgequollen sind. Die HGs haben eine flexible, gummiartige und weiche Textur, die dem menschlichen Gewebe ähnelt und sich hervorragend für die Wundbehandlung eignet. Hydrogele sind besonders vorteilhaft, weil sie Wasserverluste und Sekundärinfektionen verhindern, Wundflüssigkeiten absorbieren und für einen ausreichenden Gasaustausch sorgen können. Aufgrund der amorphen Struktur von Gellan-Gummi-Chitosan (GGCH) können Hydrogele (HGs) bis zu 99 % ihres Eigengewichts an Wasser aufnehmen.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Wound is a rupture in the epithelial integrity of the skin which consequenced from aggression or trauma and could be chased by disruption of the structure and role of underlying normal tissue. It has been stated that hyperglycaemia make a toxic effect on wound healing through the formation of advanced glycation end-products which persuade the creation of inflammatory molecules (TNF-, IL-1) and hindered with collagen synthesis. With the high glucose level also changes to cellular morphology, reduce proliferation, granulation tissue was lacking in collagen and abnormal differentiation of keratinocytes. Hydrogel (HGs) is the networks of three-dimensional polymer which swollen by huge amounts of a solvent. The HGs have flexible, rubbery and soft texture, resembles on human tissues with influential contention as wound application. Hydrogels are particularly advantageous because they can prevent water loss and secondary infection, absorb wound fluids and provide adequate gaseous exchange. Due to the amorphous structure of the Gellan gum -Chitosan (GGCH) Hydrogel (HGs) can take water up to 99% its own weight 56 pp. Englisch.…

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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 52 pp. Spanisch.

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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kashaw Sushil KumarDr. Sushil K. Kashaw is an Assistant Professor at the Harisingh Gour University, Sagar, India. He obtained his Postdoc from Wayne State University, Detroit, USA. He has 70 publications, five research grants, author. …

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 52 pp. Französisch.

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - La herida es una ruptura de la integridad epitelial de la piel que se produce como consecuencia de una agresión o un traumatismo y que puede estar perseguida por la alteración de la estructura y la función del tejido normal subyacente. Se ha afirmado que la hiperglucemia tiene un efecto tóxico en la cicatrización de heridas a través de la formación de productos finales de glicación avanzada que inducen la creación de moléculas inflamatorias (TNF-, IL-1) y dificultan la síntesis de colágeno. Con el alto nivel de glucosa también se producen cambios en la morfología celular, se reduce la proliferación, el tejido de granulación carece de colágeno y se produce una diferenciación anormal de los queratinocitos. Los hidrogeles (HG) son redes de polímeros tridimensionales que se hinchan con grandes cantidades de disolvente. Los hidrogeles tienen una textura flexible, gomosa y suave que se asemeja a la de los tejidos humanos, con una gran influencia en la aplicación en heridas. Los hidrogeles son especialmente ventajosos porque pueden evitar la pérdida de agua y la infección secundaria, absorber los fluidos de la herida y proporcionar un intercambio gaseoso adecuado. Debido a la estructura amorfa de la goma Gellan-Chitosan (GGCH), los hidrogeles pueden absorber agua hasta un 99% de su propio peso.…

Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Wound is a rupture in the epithelial integrity of the skin which consequenced from aggression or trauma and could be chased by disruption of the structure and role of underlying normal tissue. It has been stated that hyperglycaemia make a toxic effect on wound healing through the formation of advanced glycation end-products which persuade the creation of inflammatory molecules (TNF-, IL-1) and hindered with collagen synthesis. With the high glucose level also changes to cellular morphology, reduce proliferation, granulation tissue was lacking in collagen and abnormal differentiation of keratinocytes. Hydrogel (HGs) is the networks of three-dimensional polymer which swollen by huge amounts of a solvent. The HGs have flexible, rubbery and soft texture, resembles on human tissues with influential contention as wound application. Hydrogels are particularly advantageous because they can prevent water loss and secondary infection, absorb wound fluids and provide adequate gaseous exchange. Due to the amorphous structure of the Gellan gum -Chitosan (GGCH) Hydrogel (HGs) can take water up to 99% its own weightVDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 56 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 52 pp. Russisch.

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Sahu PrashantDr Prashant Sahu is a CSIR-Research Associate in DOPS, Dr H.S. Gour University, Sagar, India. He obtained his PhD degree from the same university and completed his master s degree from SIPS college Sagar. He published 2 .…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The concept of this book is focused on transdermal Nanogel therapy against skin cancer. Skin cancer is the type of cancer which arises from skin, invades other part of the body and one of the most common types of cancer with increasing number of cases worldwide. From last few decades the advancement of transdermal drug delivery system is on the peak and when the disease needle pointed towards cancer especially skin cancer, transdermal delivery systems emerged as the first choice of treatment by virtue of patient compliance. Nanogels are the nano-sized system of their parent hydro gels, establishing high water uptake ability, swelling capability, degradability, pH-sensitivity and shows promising role in controlled delivery of therapeutics, delivery of cell, wound healing and tissue engineering. The prime objective of this silhouette was to investigate the anticancer potential of transdermal nanogel consisting anticancer drug against melanoma. The book highlights the enhanced onsite targeting potential of nanogel encapsulating anticancer drug offering offers patient compliance, decreasing dose frequency and opening novel avenue against treatment of skin cancer in clinical platform.…

Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -La herida es una ruptura de la integridad epitelial de la piel que se produce como consecuencia de una agresión o un traumatismo y que puede estar perseguida por la alteración de la estructura y la función del tejido normal subyacente. Se ha afirmado que la hiperglucemia tiene un efecto tóxico en la cicatrización de heridas a través de la formación de productos finales de glicación avanzada que inducen la creación de moléculas inflamatorias (TNF-, IL-1) y dificultan la síntesis de colágeno. Con el alto nivel de glucosa también se producen cambios en la morfología celular, se reduce la proliferación, el tejido de granulación carece de colágeno y se produce una diferenciación anormal de los queratinocitos. Los hidrogeles (HG) son redes de polímeros tridimensionales que se hinchan con grandes cantidades de disolvente. Los hidrogeles tienen una textura flexible, gomosa y suave que se asemeja a la de los tejidos humanos, con una gran influencia en la aplicación en heridas. Los hidrogeles son especialmente ventajosos porque pueden evitar la pérdida de agua y la infección secundaria, absorber los fluidos de la herida y proporcionar un intercambio gaseoso adecuado. Debido a la estructura amorfa de la goma Gellan-Chitosan (GGCH), los hidrogeles pueden absorber agua hasta un 99% de su propio peso.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 52 pp. Spanisch.…