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Transmethylations and the Central Nervous System (Monographien aus dem Gesamtgebiete der Psychiatrie)
Andreoli, V. M. (Editor) / Agnoli, A. (Editor) / Fazio, C. (Editor)
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - V M. ANDREOLl, A. AGNOLI, and C. FAZIO The transfer of a methyl group from a donor to an acceptor compound is a fundamental biochemie al process long since known to biologists; the process is involved, for instance, in the metabolism of porphyrins, n…uc1eic acids, and fatty acids. Only recently, however, did transmethylation processes reveal their decisive role in CNS biochemistry - namely with the discovery that such processes are linked with the biogenie amines that have been conc1usively identified as the chemical mediators of neu ronal transmission and, more broadly, of behavior. The first suggestion that transmethylation processes might be involved in the origina tion of certain mental diseases came from Harley-Mason (1952), who noticed that many of the hallucinogenic substances known at that time contained methyl radicals, and par ticularly that mescaline represented the product of O-methylation of dopamine in posi tions 3, 4, and 5. This hypothesis was put forward when the O-methylation of catechol amines by catechol-O-methyltransferases had not yet been described. Harley-Mason further proposed that in the living organism the process of O-methyla tion might follow a 'deviant' metabolie pathway, and that the accumulation of abnor mal methylated metabolites endowed with hallucinogenic properties might be responsi ble for the implementation of some mental diseases, notably schizophrenia. He also called attention to a substance, 3,4-dimethoxyphenylethylamine (3,4-DMPEA) as a possible psychotogenic moleeule, on the strength of its capacity for producing cata tonia in experimental animals.

Les Documents graphiques photographiques. Analyse et conservation : Travaux du Centre de Recherches sur la Conservation des Documents Graphiques 1988-1990
Direction des Archives de France [ Flieder ( F. ) & Leclerc ( F. ) & Leroy ( M ) & Andreoli ( J.-C. ) & Simone ( V. de ) & Bonnas ]
Verlag: Archives Nationales // La Documentation Française
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Couverture souple. Zustand: Comme neuf. Edition originale. Paris 1991. 1 Volume/1. -- Comme Neuf -- Broché cousu. Format in-8°( 23,5 x 15,5 cm )( 378 gr ).----- 219 pages avec nombreux tableaux. ******************* ref 154.

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Rivista trimestrale di diritto e procedura civile. Diretta da: Antonio Cicu, Enrico Redenti, Tullio Ascarelli, Walter Bigiavi. Da: Anno I - 1947 a: Anno 68 - 2014
Andreoli M. - Ascarelli T. - Auletta G. - Azzariti G. - Barcellona P. - Bianca C.M. - Bigiavi W. - Bobbio N. - Carnelutti F. - Carraro L. - Carresi F. - Cassese S. - Cicu A. - Contursi Lisi L. - Dalmartello A. - Denti V. - Ferri L. - Formiggini A. - Furno C. - Galgano F. - Giampiccolo G. - Giorgianni M. - Gorla G. - Grassetti C. - Irti N. - Liebman E.T. - Mengoni L. - Messineo F. - Mignoli A. - Minervini G. - Minoli E. - Mirabelli G. - Natoli U. - Nigro M. - Oppo G. - Pino A. - Pizzorusso A. - Pugliatti S. - Redenti A. - Santoro Passarelli F. - Satta S. - Taruffo M. - Trabucchi A. et alii
Verlag: Giuffrè 1947-2014, Milano 1947
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Dal 1947 al 2014 per un totale di 68 annate. 10 tomi presentano delle scoloriture al dorso Collezione completa dei primi 68 anni della rivista Dal 1947 al 2014 per un totale di 68 annate in-8.

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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. V M. ANDREOLl, A. AGNOLI, and C. FAZIO The transfer of a methyl group from a donor to an acceptor compound is a fundamental biochemie al process long since known to biologists the process is involved, for instance, in t…he metabolism of porphyrins, nuc1eic .

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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -V M. ANDREOLl, A. AGNOLI, and C. FAZIO The transfer of a methyl group from a donor to an acceptor compound is a fundamental biochemie al process long since known to biologists; the process is involved, for instance, in the metabolism…of porphyrins, nuc1eic acids, and fatty acids. Only recently, however, did transmethylation processes reveal their decisive role in CNS biochemistry - namely with the discovery that such processes are linked with the biogenie amines that have been conc1usively identified as the chemical mediators of neu ronal transmission and, more broadly, of behavior. The first suggestion that transmethylation processes might be involved in the origina tion of certain mental diseases came from Harley-Mason (1952), who noticed that many of the hallucinogenic substances known at that time contained methyl radicals, and par ticularly that mescaline represented the product of O-methylation of dopamine in posi tions 3, 4, and 5. This hypothesis was put forward when the O-methylation of catechol amines by catechol-O-methyltransferases had not yet been described. Harley-Mason further proposed that in the living organism the process of O-methyla tion might follow a 'deviant' metabolie pathway, and that the accumulation of abnor mal methylated metabolites endowed with hallucinogenic properties might be responsi ble for the implementation of some mental diseases, notably schizophrenia. He also called attention to a substance, 3,4-dimethoxyphenylethylamine (3,4-DMPEA) as a possible psychotogenic moleeule, on the strength of its capacity for producing cata tonia in experimental animals. 196 pp. Englisch.

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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -V M. ANDREOLl, A. AGNOLI, and C. FAZIO The transfer of a methyl group from a donor to an acceptor compound is a fundamental biochemie al process long since known to biologists; the process is involved, for instance, in the metabolism of p…orphyrins, nuc1eic acids, and fatty acids. Only recently, however, did transmethylation processes reveal their decisive role in CNS biochemistry - namely with the discovery that such processes are linked with the biogenie amines that have been conc1usively identified as the chemical mediators of neu ronal transmission and, more broadly, of behavior. The first suggestion that transmethylation processes might be involved in the origina tion of certain mental diseases came from Harley-Mason (1952), who noticed that many of the hallucinogenic substances known at that time contained methyl radicals, and par ticularly that mescaline represented the product of O-methylation of dopamine in posi tions 3, 4, and 5. This hypothesis was put forward when the O-methylation of catechol amines by catechol-O-methyltransferases had not yet been described. Harley-Mason further proposed that in the living organism the process of O-methyla tion might follow a 'deviant' metabolie pathway, and that the accumulation of abnor mal methylated metabolites endowed with hallucinogenic properties might be responsi ble for the implementation of some mental diseases, notably schizophrenia. He also called attention to a substance, 3,4-dimethoxyphenylethylamine (3,4-DMPEA) as a possible psychotogenic moleeule, on the strength of its capacity for producing cata tonia in experimental animals.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 196 pp. Englisch.