Vijaykumar nagabandi (6 Ergebnisse)
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Taschenbuch. Zustand: Neu. Novel Techniques to Enhance Bioavailability of Poorly Soluble Drugs | Vijaykumar Nagabandi (u. a.) | Taschenbuch | 292 S. | Englisch | 2018 | LAP LAMBERT Academic Publishing | EAN 9783659894350 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]…preigu[dot]de | Anbieter: preigu.
Novel Techniques to Enhance Bioavailability of Poorly Soluble Drugs
Nagabandi, Vijaykumar, Tadikonda, Rama Rao, Narasimha, Jayav
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Therapeutic effectiveness of a drug depends upon the bioavailability and ultimately on the solubility of drug molecules. Solubility is one of the important parameter to achieve desired concentration of drug in systemic circulation tha…t produces pharmacological response. Currently only 8% of new drug candidates have both high solubility and permeability. Aqueous solubility of any therapeutically active substance is a key property; it governs dissolution, absorption and thus the In Vivo efficacy. For highly permeable and poorly soluble drug the rate of its oral absorption is often controlled by the dissolution rate in the gastrointestinal tract. The poor dissolution rate of waterinsoluble drugs is still a major problem confronting the pharmaceutical industry. There are several techniques to enhance the dissolution of poorly soluble drugs.The main objective of this work is to develop and explore new formulations for enhancing the bioavailability of highly permeable and poorly soluble nonsteroidal antiinflamatory drugs like Ketoprofen and Naproxen. To achieve this, it is planned to use different novel techniques such as liquisolid compacts and melt granulation. 292 pp. Englisch.
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Nagabandi VijaykumarDr. Vijaykumar Nagabandi, is currently working as Formulation Research Scientist, at Neuheit Pharma Technologies Pvt Ltd. His research is focussed on improving bioavailability of poorl…y soluble drugs. He authore.
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Therapeutic effectiveness of a drug depends upon the bioavailability and ultimately on the solubility of drug molecules. Solubility is one of the important parameter to achieve desired concentration of drug in systemic circulation that pr…oduces pharmacological response. Currently only 8% of new drug candidates have both high solubility and permeability. Aqueous solubility of any therapeutically active substance is a key property; it governs dissolution, absorption and thus the In Vivo efficacy. For highly permeable and poorly soluble drug the rate of its oral absorption is often controlled by the dissolution rate in the gastrointestinal tract. The poor dissolution rate of waterinsoluble drugs is still a major problem confronting the pharmaceutical industry. There are several techniques to enhance the dissolution of poorly soluble drugs.The main objective of this work is to develop and explore new formulations for enhancing the bioavailability of highly permeable and poorly soluble nonsteroidal antiinflamatory drugs like Ketoprofen and Naproxen. To achieve this, it is planned to use different novel techniques such as liquisolid compacts and melt granulation.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 292 pp. Englisch.
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Therapeutic effectiveness of a drug depends upon the bioavailability and ultimately on the solubility of drug molecules. Solubility is one of the important parameter to achieve desired concentration of drug in systemic circulation that pro…duces pharmacological response. Currently only 8% of new drug candidates have both high solubility and permeability. Aqueous solubility of any therapeutically active substance is a key property; it governs dissolution, absorption and thus the In Vivo efficacy. For highly permeable and poorly soluble drug the rate of its oral absorption is often controlled by the dissolution rate in the gastrointestinal tract. The poor dissolution rate of waterinsoluble drugs is still a major problem confronting the pharmaceutical industry. There are several techniques to enhance the dissolution of poorly soluble drugs.The main objective of this work is to develop and explore new formulations for enhancing the bioavailability of highly permeable and poorly soluble nonsteroidal antiinflamatory drugs like Ketoprofen and Naproxen. To achieve this, it is planned to use different novel techniques such as liquisolid compacts and melt granulation.
