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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This edition of the Proceedings of the 9th European Symposium on Structure-Activity Relationships: QSAR and Molecular Modelling held from September 7-11, 1992 in Strasbourg, France deals with various areas of structure-activity relationships and their applications in the design of new drugs. The approximately 175 contributions in the book highlight the interdisciplinary approach between QSAR, molecular modelling and databank-based research in the design and development process of new drug candidates, and demonstrates the efficacy of these techniques by introducing rationalization at a very early stage in the discovery of bioactive compounds. Internationally renowned specialists review methodologies in the field of SAR concepts and computer-assisted drug design, covering such topics as: De novo design X-ray and NMR-based drug design Parameters and interactions. Molecular modelling Molecular similarity 3D QSAR.…

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paperback. Zustand: New. Ship out in 2 business day, And Fast shipping, Free Tracking number will be provided after the shipment.Pub Date :2005-04-01 Publisher: The World Publishing Company innovative medicinal chemistry is the study and once studied abroad more than 50 young scholars to translate. and many people are still working or studying overseas. They grasp and understanding of foreign advanced technology and experience of drug research and development. eager to make their own applications for the development of the pharmaceutical industry in the motherland contribution. Book is divided into eight parts. 43 chapters. including pharmaceutical chemistry from drug discovery to all new drug. not only systematically expounded the traditional content. also details new drug research and development of the latest technologies and methods. as well as you the author personal experience in the application of these methods and techniques and insights. The content of the book translated accurate. easy to understand. the teachers and students of the the drug research workers and vulgar chemists engaged in pharmaceutical research. and the Medical Colleges is a rare reference books. the leadership of enterprises and research institutions decision-making is also an important reference value. About the author: Gamille-Georges Wermuth. Ph.D. Professor. Prestwick Chemical company founder. Organic Chemistry and a professor of medicinal chemistry in 1969 - 2002 for France. Louis Pasteur University College of Pharmacy. Early in the French Navy in Toulon. France. Centre d'Etudes Phys-iobiologiques Appliquees a la Marine serving two years on the medicinal chemistry generated strong interest. At that time. he is working under the guidance of Dr. Henri Laborit while the Dr. Henri Laborit I is the inventor of the artificial hibernation. and found that chlorpromazine (also called wintermin). Contents of Medicinal Chemistry Summary Chapter 1 A Brief History of drug development - from plant extracts to changes in gene technology in Chapter 2. the definition of medicinal chemistry and purpose. the three stages of the drug action and drug and disease classification in Chapter 3 drugs Determination of the effect. said the source of Chapter 6 Chapter 5 Chapter 4 drug target - the second part of the molecular mechanism of the drug action lead compound discovery of new lead compounds to explore methods and its own research methods drugs and lead compounds - The application of combinatorial chemistry of natural products Chapter 7 Chapter 8 Molecular Biology of the foundation in the development of new drugs Chapter 9 - Chapter 11 of Chapter 10 of the lead compound high-speed chemical library - the evaluation of drug-like network found by searching the database computer-aided screening Express - Internet and Medicinal Chemistry third part of the structure - activity relationship of basic research Chapter 12 homologues molecular diversity - polyethylene matter and biphenyl material Chapter 13 isostere replacement based molecular transformation Chapter 14 Chapter 15 Medicinal Chemistry of the ring structure of the transformation of the conformational constraints and steric hindrance optical isomers Chapter 18 Chapter 16 the same molecule the twin drugs and different molecular twin drugs of Chapter 17 drugs preliminary structure - activity relationship studies first four parts to replace the basic functional groups (qualitative and quantitative aspects of the structure - activity relationship) Chapter 21 of Chapter 20 of Chapter 19 of the effect of substituents functional groups in the drug - receptor interaction compounds the nature and quality of medicines quantitative Chapter 22 the fifth part of the structure - activity relationship stereochemistry stereochemical factors I receptor image and molecular model of Chapter 23 of the mechanism of drug action (conformational constraints. steric hindrance and hydrophobic packing) Chapter 24 pharmacophore identify and receptor image Chapter. …

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of the 9th European Symposium on Structure-Activity Relationships, September 7-11, 1992, Strasbourg, France This edition of the Proceedings of the 9th European Symposium on Structure-Activity Relationships: QSAR and Molecular Modelli.…

Buch. Zustand: Neu. Trends in QSAR and Molecular Modelling 92 | Proceedings of he 9th European Symposium on Structure-Activity Relationships: QSAR and Molecular Modelling September 7 -11, 1992, Strasbourg, France | C. G. Wermuth | Buch | Einband - fest (Hardcover) | Englisch | 1993 | Springer Netherland | EAN 9789072199133 | Verantwortliche Person für die EU: Springer Netherlands, Haberstr. 7, 69126 Heidelberg, buchhandel-buch[at]springer[dot]com | Anbieter: preigu Print on Demand.…

Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This edition of the Proceedings of the 9th European Symposium on Structure-Activity Relationships: QSAR and Molecular Modelling held from September 7-11, 1992 in Strasbourg, France deals with various areas of structure-activity relationships and their applications in the design of new drugs. The approximately 175 contributions in the book highlight the interdisciplinary approach between QSAR, molecular modelling and databank-based research in the design and development process of new drug candidates, and demonstrates the efficacy of these techniques by introducing rationalization at a very early stage in the discovery of bioactive compounds.Internationally renowned specialists review methodologies in the field of SAR concepts and computer-assisted drug design, covering such topics as: De novo designX-ray and NMR-based drug designParameters and interactions.Molecular modellingMolecular similarity3D QSAR.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 624 pp. Englisch.…

Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This edition of the Proceedings of the 9th European Symposium on Structure-Activity Relationships: QSAR and Molecular Modelling held from September 7-11, 1992 in Strasbourg, France deals with various areas of structure-activity relationships and their applications in the design of new drugs. The approximately 175 contributions in the book highlight the interdisciplinary approach between QSAR, molecular modelling and databank-based research in the design and development process of new drug candidates, and demonstrates the efficacy of these techniques by introducing rationalization at a very early stage in the discovery of bioactive compounds. Internationally renowned specialists review methodologies in the field of SAR concepts and computer-assisted drug design, covering such topics as: De novo design X-ray and NMR-based drug design Parameters and interactions. Molecular modelling Molecular similarity 3D QSAR. 624 pp. Englisch.…