Isbn: 9786139912087 - solid self micron emulsifying drug delivery system of rosuvastatin: noval drug delivery system (ssmedds) - rosuvastatin calcium (14 Ergebnisse)

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Taschenbuch. Zustand: Neu. Solid Self Micron Emulsifying Drug Delivery System of Rosuvastatin | Noval Drug Delivery System (SSMEDDS) - Rosuvastatin Calcium | Amit Vishwakarma | Taschenbuch | 92 S. | Englisch | 2020 | LAP LAMBERT Academic Publishing | EAN 9786139912087 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The objective of present research work was to develop a self-emulsifying drug delivery system of Rosuvastatin Calcium (RC) for increasing its solubility, and oral bioavailability. Solubility of RC was determined in various vehicles. Oil, Surfactant and Cosurfactant were selected based on the solubility and HLB (Hydrophilic lipophilic balance) value. To identify the microemulsion existing zone Pseudo-ternary phase diagrams were constructed. Solubility analysis was also done for optimization of formulation. The optimised microemulsion formulation was evaluated for Powder X-Ray Diffraction (XRD), SEM (Scanning electron microscopy) analysis, globule size, zeta potential and phase separation study. Average globule size and zeta potential of the optimized microemulsion formulation were found to be 30 nm, and -11.5 mV, respectively. The viscosity and conductivity data indicated that the microemulsion was of the o/w type.The solubility of RC was successfully enhanced up to 82.32%. Percent drug release at the end of 60 min was found to be 76.74 %. The solubility of Rosuvastatin Calcium was significantly enhanced after formulating into self-emulsify microemulsion. 92 pp. Englisch.…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The objective of present research work was to develop a self-emulsifying drug delivery system of Rosuvastatin Calcium (RC) for increasing its solubility, and oral bioavailability. Solubility of RC was determined in various vehicles. Oil, Surfactant and Cosurfactant were selected based on the solubility and HLB (Hydrophilic lipophilic balance) value. To identify the microemulsion existing zone Pseudo-ternary phase diagrams were constructed. Solubility analysis was also done for optimization of formulation. The optimised microemulsion formulation was evaluated for Powder X-Ray Diffraction (XRD), SEM (Scanning electron microscopy) analysis, globule size, zeta potential and phase separation study. Average globule size and zeta potential of the optimized microemulsion formulation were found to be 30 nm, and -11.5 mV, respectively. The viscosity and conductivity data indicated that the microemulsion was of the o/w type.The solubility of RC was successfully enhanced up to 82.32%. Percent drug release at the end of 60 min was found to be 76.74 %. The solubility of Rosuvastatin Calcium was significantly enhanced after formulating into self-emulsify microemulsion.…

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vishwakarma Amit-Amit Kumar VishwakarmaMaster of Pharmacy in Pharmaceutics from Amity University Uttar Pradesh, Lucknow.7 publication in indexed journals.Professional Experience6 yrs of rich experience in diabetes and metabolism ther.…

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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The objective of present research work was to develop a self-emulsifying drug delivery system of Rosuvastatin Calcium (RC) for increasing its solubility, and oral bioavailability. Solubility of RC was determined in various vehicles. Oil, Surfactant and Cosurfactant were selected based on the solubility and HLB (Hydrophilic lipophilic balance) value. To identify the microemulsion existing zone Pseudo-ternary phase diagrams were constructed. Solubility analysis was also done for optimization of formulation. The optimised microemulsion formulation was evaluated for Powder X-Ray Diffraction (XRD), SEM (Scanning electron microscopy) analysis, globule size, zeta potential and phase separation study. Average globule size and zeta potential of the optimized microemulsion formulation were found to be 30 nm, and -11.5 mV, respectively. The viscosity and conductivity data indicated that the microemulsion was of the o/w type.The solubility of RC was successfully enhanced up to 82.32%. Percent drug release at the end of 60 min was found to be 76.74 %. The solubility of Rosuvastatin Calcium was significantly enhanced after formulating into self-emulsify microemulsion.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 92 pp. Englisch.…