mdpi ag mär 2018 (4 Ergebnisse)

Taschenbuch. Zustand: Neu. Neuware - Shape memory alloys (SMAs) have special property of the shape memory effect. After thermal treatment above the martensitic transition temperature, the alloys come back to the original shape when the alloys heat again after having cooled it to the temperature that is lower than the martensitic transition temperature. By means of this property, many industrial parts and systems were produced. This Special Issue 'Shape Memory Alloys 2017' is constructed articles reporting new and progressive research results, as well as reviews of particular classes of fundamental physics of the materials and their applications of SMAs. Through its 17 efficient articles, the reader will approach to researches related to SMAs with their peculiar magnetic, thermo-mechanical properties, superelasticity, plastic deformation and compression under pressure. These physical properties introduce a large number of applications as faster SMA actuators, application of medical devices, industrial joining parts, volts, and magnetic/mechanical/thermal sensors. These articles are intended scientific researchers, professional engineers, students to obtain a better understanding in this field lately.

Taschenbuch. Zustand: Neu. Neuware - Catechols are widely found in nature taking part in a variety of biological functions, ranging from the aqueous adhesion of marine organisms to the storage of transition metal ions. Catechol-based natural and biomimetic molecules have thus been the focus of intense research aimed at mimicking and translating this nature-inspired chemistry into new functional materials and systems with tailored properties. The aim of this book is to present a concise survey of the state-of-the-art of basic and applied research on bioinspired catechol systems. It collects several cutting-edge contributions from leading laboratories with a unifying theme of biomimetic principles and approaches. It is hoped that both practitioners and newcomers to the field will by fascinated by the unique potential of biomimetics to pursue new research and innovative solutions in biomedicine and technology.

Taschenbuch. Zustand: Neu. Neuware - A hallmark of inflammation is the accumulation of leukocytes, which can serve to remove pathogens and necrotic tissue, but may also damage healthy tissue and exacerbate the inflammatory response. Our understanding of leukocyte recruitment in inflammation was revolutionized in the late 1980s by the discovery of chemokines (chemotactic cytokines), a family of small, secreted proteins that induce migration of selective subsets of leukocytes. Shortly afterwards, chemokines were found to exert their functions through the now familiar chemokine receptors, members of the G protein-coupled receptor superfamily. As their physiological and pathological functions were elucidated, chemokine receptors have become popular targets for drug development in inflammatory diseases as well as cancer metastasis and HIV infection. Extensive research has revealed that the functions of chemokines and their receptors are regulated at numerous levels, including: genetic mutations/polymorphisms; control of expression levels; ligand internalization via functional or decoy receptors; intrinsic selectivity of chemokine-receptor binding; hetero- or homo-oligomerization of chemokines or of receptors; alternative signalling pathways; interaction of chemokines with glycosaminoglycans; post-translational modifications; and binding to pathogen-derived inhibitors. This Special Issue of IJMS focused on the natural and pharmacological mechanisms by which the activities of chemokines and their receptors can be regulated.

Taschenbuch. Zustand: Neu. Neuware - This Special Issue 'Advanced Nanoindentation in Materials' contains some of the latest developments in the field of small-scale contact mechanics for a wide range of materials and biological cells. The featured manuscript revealed a new ultra-high strain rate nanoindentation method that will enable new scientific understanding of time-dependent material properties. The book also presents unique material properties of super alloys and other structural materials characterized by indentation methods. In addition to engineering materials, deformation behaviors of live cancer cells on sharp pillar structures were discussed in this book with the hope to stimulate interest in the mechanical contact behaviors of biological cells.