springer new york aug 2009 (47 Ergebnisse)

Buch. Zustand: Neu. Neuware - It's been thirty-five years since people last trod the dusty plains of the Moon. Over the course of six landings from 1969 to 1972, twelve men explored, four-wheeled, dug and hiked across the lunar surface. Now, NASA has plans for a seventh landing on the Moon. This time, they want to stay. NASA's plans, dubbed the Constellation architecture, involve the largest launch vehicle ever built, new types of propulsion, and a six-person vehicle to ferry crews from Earth to the Moon. But NASA's plans go far beyond Luna. Eventually, the lessons learned on the Moon's outpost at Shackleton Crater will teach us how to live-permanently-on the most Earthlike world in our solar system, Mars. NASA will have company: plans for future lunar exploration are being drawn by Europe, Japan, China and India.While specific hardware and mission details will be in flux for some time, the overarching goals, strategies and inspiration for the seventh landing will not change. This book will choose a typical scenario for getting to the Moon that embraces the spirit of exploration embodied by NASA's Constellation architecture. Each chapter moves from a general description to the specific nuts-and-bolts of engineering and science. The Seventh Landing reveals the very latest strategies for how we'll get to the Moon, what we know today, what we want to find out, and what life will be like at the first true outposts on the Moon and Mars.

Taschenbuch. Zustand: Neu. Neuware -Cancer and aging are integrally related. Cancer incidence and mortality increase with age, with most cancer diagnoses and deaths occurring in patients aged 65 and older. The aging of the Baby Boomer population, along with an overall increase in life expectancy, points to a doubling of the U.S. population over age 65 by the year 2030. This demographic shift, combined with the known association of cancer and aging, is expected to bring about a rapid growth in the older cancer-patient population. It is clear that geriatric principles must become part of oncology care. The evaluation and development of treatment recommen- tions for an older adult with cancer can be challenging for many reasons. Tumor biology and response to therapy are affected by age. In addition, age-related factors may impact treatment patterns, tolerance, and efficacy. These age-related factors include functional status declines, comorbid conditions, changes in cognitive function, weakening of organ function, decreases in physiologic reserve, and faltering social support.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 356 pp. Englisch.

Buch. Zustand: Neu. Neuware -The main intended audience for this book is undergraduate students in pure and applied sciences, especially those in engineering. Chapters 2 to 4 cover the probability theory they generally need in their training. Although the treatment of the subject is surely su cient for non-mathematicians, I intentionally avoided getting too much into detail. For instance, topics such as mixed type random variables and the Dirac delta function are only brie y mentioned. Courses on probability theory are often considered di cult. However, after having taught this subject for many years, I have come to the conclusion that one of the biggest problems that the students face when they try to learn probability theory, particularly nowadays, is their de ciencies in basic di erential and integral calculus. Integration by parts, for example, is often already forgotten by the students when they take a course on probability. For this reason, I have decided to write a chapter reviewing the basic elements of di erential calculus. Even though this chapter might not be covered in class, the students can refer to it when needed. In this chapter, an e ort was made to give the readers a good idea of the use in probability theory of the concepts they should already know. Chapter 2 presents the main results of what is known as elementary probability, including Bayes¿ rule and elements of combinatorial analysis.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 360 pp. Englisch.

Buch. Zustand: Neu. Neuware - For any organization to perform and compete successfully, it must have the systems and processes in place to translate goals into achievable actions-and to measure and monitor results. Moreover, the organization must be able to adjust and adapt as market conditions, technologies, the competitive environment, government regulations, personnel, and other variables evolve, sometimes gradually and sometimes dramatically.In Delivering Results: Measuring What Matters, Babson College professors and management consultants, Lawrence Carr and Alfred Nanni, show managers how to avoid the common pitfalls and mistakes when setting corporate strategy, and instead create a management system-unique to their organization-that aligns internal resources with objectives, motivates and rewards employees, and continuously provides feedback. Illustrating their concepts with numerous real-life examples (both successes and failures), practical tools and models, and a glossary of key terms, the authors demonstrate that knowing how to create and direct management systems that deliver results is, in itself, a strategic resource.

Taschenbuch. Zustand: Neu. Neuware -Since the terrorist attack on the United States on September 11, 2001 and subsequent cases of anthrax in Florida and New York City, attention has been focused on the threat of b- logical warfare and bioterrorism. Biological warfare agents are de ned as ¿living org- isms, whatever their nature, or infected material derived from them, which are used for h- tile purposes and intended to cause disease or death in man, animals and plants, and depend for their efforts on the ability to multiply in person, animal or plant attacked.¿ Biological warfare agents may be well suited for bioterrorism to create havoc and terror in a civilian population, because they are cheap and easy to obtain and dispense. Infectious or contagious diseases have played a major part in the history of warfare ¿ deliberately or inadvertently ¿ in restricting or assisting invading armies over the centuries. In 1346, the Tartars catapulted plaque-infected bodies into Kaffa in the Crimea to end a 3-year siege. Blankets contaminated with smallpox to infect North American Indians were used by British forces in the 18th century. More recently, the Japanese released eas infected with plaque in Chinese cities in the 1930s and 1940s. Biological research programs for both offensive and defensive strategies have been developed by the United States, Britain, the former Soviet Union, and Canada; several other nations are thought to have such programs.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 292 pp. Englisch.

Buch. Zustand: Neu. Neuware -We all long for peace within ourselves, families, communities, countries, and throughout the world. We wonder what we can do about the multitude of con icts currently wreaking havoc across the globe and the continuous reports of violence in communities as well as within families. Most of the time, we contemplate solutions beyond our reach, and overlook a powerful tool that is at our disposal: forgiveness. As a genocide survivor, I know something about it. As the genocide unfolded in Rwanda in 1994, I was devastated by what I believed to be the inevitable deaths of my loved ones. The news that my parents and my seven siblings had indeed been killed was simply unbearable. Anger and bitterness became my daily companions. Likewise, I continued to wonder how the Hutus and Tutsis in Rwanda could possibly reconcile after one of the most horrendous genocides of the 20th century. It was not until I came to understand the notion of forgiveness that I was able to see the light at the end of the tunnel. Common wisdom suggests that forgiveness comes after a perpetrator makes a genuine apology. This wisdom informs us that in the aftermath of a wrongdoing, the offender must acknowledge the wrong he or she has done, express remorse, express an apology, commit to never repeating said harm, and make reparations to theextentpossible.Onlythencanthevictimforgiveandagreetoneverseekrevenge.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 328 pp. Englisch.

Buch. Zustand: Neu. Neuware -This groundbreaking text has been established as the market leader throughout the world. Profusely illustrated, Transmission Electron Microscopy: A Textbook for Materials Science provides the necessary instructions for successful hands-on application of this versatile materials characterization technique. For this first new edition in 12 years, many sections have been completely rewritten with all others revised and updated. The new edition also includes an extensive collection of questions for the student, providing approximately 800 self-assessment questions and over 400 questions that are suitable for homework assignment. Four-color illustrations throughout also enhance the new edition.Praise for the first edition:`The best textbook for this audience available.' ¿ American Scientist`Ideally suited to the needs of a graduate level course. It is hard to imagine this book not fulfilling most of the requirements of a text for such a course.' ¿ Microscope`This book is written in such a comprehensive manner that it is understandable to all people who are trained in physical science and it will be useful both for the expert as well as the student.' ¿ Micron`The book answers nearly any question - be it instrumental, practical, or theoretical - either directly or with an appropriate reference.This book provides a basic, clear-cut presentation of how transmission electron microscopes should be used and of how this depends specifically on one's specific undergoing project.' ¿ MRS Bulletin, May 1998`The only complete text now available which includes all the remarkable advances made in the field of TEM in the past 30-40 years.The authors can be proud of an enormous task, very well done.' ¿ from the Foreword by Professor Gareth Thomas, University of California, BerkeleySpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 840 pp. Englisch.

Buch. Zustand: Neu. Neuware - This text presents mathematical biology as a field with a unity of its own, rather thanonly the intrusion of one science into another.It updates anearlier successful edition and greatly expands the concept of the 'computer biology laboratory,' giving students a general perspective of the field before proceeding to more specialized topics. The book focuses on problems of contemporary interest, such as cancer, genetics, and the rapidly growing field of genomics. It includes new chapters on parasites, cancer, and phylogenetics, along with an introduction to online resources for DNA, protein lookups, and popular pattern matching tools such as BLAST. In addition, the emerging field of algebraic statistics is introduced and its power illustrated in the context of phylogenetics.A unique feature of the book isthe integration of a computer algebra system into the flow of ideas in a supporting but unobtrusive role. Syntax for both the Maple and Matlab systems is provided in a tandem format. The use of a computer algebra system gives the students the opportunity to examine 'what if' scenarios, allowing them to investigate biological systems in a way never before possible. For students without access to Maple or Matlab, each topic presented is complete. Graphic visualizations are provided for all mathematical results.Mathematical Biology includes extensive exercises, problems and examples. A year of calculus with linear algebra is required to understand the material presented. The biology presented proceeds from the study of populations down to the molecular level; no previous coursework in biology is necessary. The book is appropriate for undergraduate and graduate students studying mathematics or biology and for scientists and researchers who wish to study the applications of mathematics and computers in the natural sciences.

Buch. Zustand: Neu. Neuware -Poverty is a paradoxical state. Recognizable in the eld for any sensitive observer who travels in remote rural areas and urban slums and meets marginalized people in a given society, poverty still remains a challenge to conceptual formalization and to measurement that is consistent with such formalization. The analysis of poverty is multidisciplinary. It goes from ethics to economics, from political science to human biology, and any type of measurement rests on mathematics. Moreover, poverty is multifaceted according to the types of deprivation, and it is also gender and age speci c. A vector of variables is required, which raises a substantial problem for individual and group comparisons necessary to equity analysis. Multidimension- ity also complicates the aggregation necessary to perform the ef ciency analysis of policies. In the case of income poverty, these two problems, equity and ef ciency, have bene ted from very signi cant progress in the eld of economics. Similar achievements are still to come in the area of multidimensional poverty. Within this general background, this book has a very modest and narrow-scoped objective. It proposes an operational methodology for measuring multidimensional poverty, independent from the conceptual origin, the size and the qualitative as well as the quantitative nature of the primary indicators used to describe the poverty of an individual, a household or a sociodemographic entity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 232 pp. Englisch.

Buch. Zustand: Neu. Neuware -Since overall circuit performance has depended primarily on transistor properties, previous efforts to enhance circuit and system speed were focused on transistors as well. During the last decade, however, the parasitic resistance, capacitance, and inductance associated with interconnections began to influence circuit performance and will be the primary factors in the evolution of nanoscale ULSI technology. Because metallic conductivity and resistance to electromigration of bulk copper (Cu) are better than aluminum, use of copper and low-k materials is now prevalent in the international microelectronics industry. As the feature size of the Cu-lines forming interconnects is scaled, resistivity of the lines increases. At the same time electromigration and stress-induced voids due to increased current density become significant reliability issues. Although copper/low-k technology has become fairly mature, there is no single book available on the promise and challenges of these next-generation technologies. In this book, a leader in the field describes advanced laser systems with lower radiation wavelengths, photolithography materials, and mathematical modeling approaches to address the challenges of Cu-interconnect technology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 444 pp. Englisch.

Buch. Zustand: Neu. Neuware -Recent and rapid progress in the field of biotechnology has resulted in an increasing number of novel macromolecular drugs with great promise for further advanced research and clinical application. However, the delivery of these macromolecular drugs by routes other than the parenteral route is difficult. The pipeline of macromolecular drugs derived from biotechnology presents a challenging opportunity to develop practical dosage forms that could be dosed via the oral route. Given this, the successful oral delivery of macromolecular drugs presents an enormous opportunity. Oral Delivery of Macromolecular Drugs will provide an overview of the innovative oral delivery technologies that have demonstrated success in human testing and will go on to cite the challenges, strategies, and future trends that are to be expected.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch.

Buch. Zustand: Neu. Neuware -From Combinatorics to Philosophy: The Legacy of G. -C. Rota provides an assessment of G. -C. Rota's legacy to current international research issues in mathematics, philosophy and computer science.This volume includes chapters by leading researchers, as well as a number of invited research papers. Rotäs legacy connects European and Italian research communities to the USA by providing inspiration to several generations of researchers in combinatorics, philosophy and computer science.From Combinatorics to Philosophy: The Legacy of G. -C. Rota is of valuable interest to research institutions and university libraries worldwide. This book is also designed for advanced-level students in mathematics, computer science, and philosophy.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 280 pp. Englisch.

Buch. Zustand: Neu. Neuware -Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives¿basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins andvaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens¿ genomes provides opportunities that never before have been available¿identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated,replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process.The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 284 pp. Englisch.

Buch. Zustand: Neu. Neuware -Data Mining and Multi agent Integration aims to re ect state of the art research and development of agent mining interaction and integration (for short, agent min ing). The book was motivated by increasing interest and work in the agents data min ing, and vice versa. The interaction and integration comes about from the intrinsic challenges faced by agent technology and data mining respectively; for instance, multi agent systems face the problem of enhancing agent learning capability, and avoiding the uncertainty of self organization and intelligence emergence. Data min ing, if integrated into agent systems, can greatly enhance the learning skills of agents, and assist agents with predication of future states, thus initiating follow up action or intervention. The data mining community is now struggling with mining distributed, interactive and heterogeneous data sources. Agents can be used to man age such data sources for data access, monitoring, integration, and pattern merging from the infrastructure, gateway, message passing and pattern delivery perspectives. These two examples illustrate the potential of agent mining in handling challenges in respective communities. There is an excellent opportunity to create innovative, dual agent mining interac tion and integration technology, tools and systems which will deliver results in one new technology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.

Buch. Zustand: Neu. Neuware - The concept for this book came about following the publication of the volume Health Issues Confronting Minority Men Who Have Sex with Men, published by Springer in 2008. Consistent with its title, that work focused on speci c health issues identi ed by communities, researchers, and AIDS service providers that were and continue to be of concern . During the preparation of that volume, I received numerous telephone calls and e-mails from women in various parts of the country, asking why a book was not also being developed to address their often-neglected concerns. Accordingly,thetopicsaddressedinIdentitiesandSexualitiesofMinorityWomen were developed based on input from minority women who participated in focus groups conducted in diverse regions of the United States. These focus groups were held speci cally to provide an opportunity for sexual minority women in minority communities to identify those issues that from their perspective are most salient and relevant to their lives. It is notsurprising, in view of the variation in process by which the topics were identi ed, as well as the differences in perspective as- ciated with differences in sex and gender, that this resulting compilation of topics departs substantially from the focus of the companion text addressing health issues of minority men who have sex with men.

Buch. Zustand: Neu. Neuware - During the last half of the nineteenth century, a number of social and economic factors converged that resulted in the rural village of Deerfield, Massachusetts becoming almost entirely female. This drastic shift in population presents a unique lens through which to study gender roles and social relations in the late nineteenth and early twentieth century. The lessons gleaned from this case study will provide new insight to the study of gender relations throughout other historical periods as well.Through an intensive examination of both historical and archaeological evidence, the author presents a clear picture of the gendered social relations in Deerfield over the span of seventy years. While gender relations in urban settings have been studied extensively, this unique work provides the same level of examination to gender relations in a rural setting. Likewise, where previous studies have often focused only on relations between married men and women, the unique case of Deerfield provides insight into the experiences of single women, particularly widows and 'spinsters'. This work presents a unique contribution that will be essential for anyone studying the historical archaeology of gender, or gender roles in the Victorian era and beyond.

Buch. Zustand: Neu. Neuware - Generally individuals in history are known for a particular reason - they somehow influenced history. Very little is known about the ordinary person who lived in the past. But historical archaeologists - through their interpretation of the material culture and historic record - can study the past on an individual level. This brings archaeological interpretation from a micro to a macro level - as opposed to the traditional level of society to community to individual interpretation.The cases presented in this volume engage material culture that is owned or used by a single person and is thus associated with an individual at some point in its uselife. The volume takes bodkins, shoes, beads, cloth, religious items, grave goods, as well as subassemblages from well-defined contexts from New England, the Chesapeake, New Orleans, Hawaii, Spanish colonial America, and London in the pursuit of the individual and the textured interpretation this analytical scale provides.This volume promises to present innovative approaches to a host of archaeological materials, drawing widely on the range of archaeological research for the historical period today. Capitalizing on several topics and research threads with great currency, such as the examination of material culture and interest in various and intersecting lines of identity construction, as well as presenting an international and multiregional approach to these topics, this volume will be of interest to archaeologists, anthropologists, material culture scholars, and social historians interested in a wide variety of time periods and subfields.

Buch. Zustand: Neu. Neuware - In the United States, work is the key to economic success, as well as the major source of health care coverage and retirement security. While Europeans look to the State for these benefits, Americans for the most part do not. This system of employment-based benefits means that those disadvantaged in the labor market are also disadvantaged in terms of health care coverage and retirement security.The authors of this work examine the overrepresentation of Mexican Americans in low wage or service sector jobs, which rarely come with health insurance or retirement coverage. At all ages, Mexican Americans have lower rates of health insurance and retirement coverage than do other minority groups, such as African Americans or other Hispanic groups. Although employment in jobs that do not provide benefits is one major source of this disparity, other factors-including immigration history, citizenship status, and language proficiency-further block opportunities for upward mobility within the Mexican American population.In their analysis, the authors work to deemphasize the popular, cultural explanation for the economic disparities and focus on more practical, policy-based solutions. In each chapter, the authors identify and critique the factors that affect the economic security and health care access of individuals throughout the life course, suggesting policies for reform.This work will be of interest to anyone working in the fields of cultural studies, public healthand the sociology of work. With the focus on real world causes for the problems as well as potential solutions, policy-makers will also find this informative book an essential resource.

Buch. Zustand: Neu. Neuware - The academic study of diamonds is as multi-faceted as the precious stones themselves. Mineralogists and geographers have written about them, as have historians and economists and students of art and fashion. They each shine their light on a different aspect of this source of luminous radiance. But who would venture to describe the entire complicated worldwide system starting in the diamond mines and ending with the consumers of Western metropolises In The Mazzel Ritual: Culture, Customs and Crime in the Diamond Trade,Russian-Israeli cultural anthropologist and criminologist Dina Siegel follows the route of a diamond from the mines of Africa to the shops of Europe and the United States, as it passes through countless hands and places and is smuggled, stolen, cut, polished, sold, exchanged and, finally, worn as jewelry. In the course of this long and exciting journey, a wide range of people face all sorts of risks and criminality, as well as various moral and ethical judgments. Siegel describes the range of ethnic groups that are active in the diamond trade and the culture and customs that are specific to this business. She analyses the dangers and threats to the industry and aims to uncover the strategies and tactics to deal with them. Finally, this story of risk, trust and crime examines the vulnerability of diamond production and distribution to illicit and criminal activities.This book is about the diamond business itself as well as about those involved in it. It tells the story of people who simply cannot stay away from this expensive and alluring commodity.

Buch. Zustand: Neu. Neuware - Bioinformatics involves specialized application of computer technology to investigative and conceptual problems in biology and medicine; neuroinformatics (NI) is the practice of bioinformatics in the neurosciences. Over the past two decades the biomedical sciences have been revolutionized by databases, data mining and data modeling techniques. The Human Genome Project, which depended on informatics methods, has been the most well recognized bioinformatics undertaking. Bioinformatics has since been applied all across biology and medicine, and has also transformed almost every avenue in neuroscience. Yet in neuropsychology, NI perspectives remain largely unrealized. Ironically, NI offers enormous potential to the essential praxis of neuropsychology - assessing cognitive behavior and relating cognition to neural systems. Neuroinformatics can be applied to neuropsychology as richly as it has been applied across the neurosciences.Neuroinformatics for Neuropsychology is the first book to explain the relevance and value of NI to neuropsychology. It systematically describes NI tools, applications and models that can enhance the efforts of neuropsychologists. It also describes the implications of NI for neuropsychology in the 21st century - fundamental shifts away from the conventional modes of research, practice and communication that have thus far characterized the field. One of the foremost experts on the subject: Illustrates the vital role NI is playing throughout the neurosciences.Provides a sampling of NI tools and applications in neuroscience research, and lays out current organization structures that support NI.Describes the lack of NI in neuropsychology, differentiates between NI systems for neuropsychology and conventional computerized assessment methods, and proposes criteria for neuropsychology-specific NI systems.DescribesNI applications and models currently in use in neuropsychology, and NI models for neuropsychology that are being pioneered in phenomics research.Discusses potential obstacles and aids to NI in neuropsychology, including issues such as data sharing, standardization of methods, and data ontology. Projects the future of neuropsychological research and practice in light of the new generation of the internet, Web 2.0, geared to collective knowledge building.A vital introduction to a profound technological practice, Neuroinformatics for Neuropsychology is important reading for clinical neuropsychologists, cognitive neuroscientists, behavioral neurologists, and speech-language pathologists. Researchers, clinicians, and graduate students interested in informatics for the brain-behavioral sciences will especially welcome this unique volume.

Buch. Zustand: Neu. Neuware -Piezoelectricity has been a steadily growing field, with recent advances made by researchers from applied physics, acoustics, materials science, and engineering. This collective work presents a comprehensive treatment of selected advanced topics in the subject. The book is written for an intermediate graduate level and is intended for researchers, mechanical engineers, and applied mathematicians interested in the advances and new applications in piezoelectricity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 344 pp. Englisch.

Buch. Zustand: Neu. Neuware -Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book presents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 452 pp. Englisch.

Buch. Zustand: Neu. Neuware - Computational inference has taken its place alongside asymptotic inference and exact techniques in the standard collection of statistical methods. Computational inference is based on an approach to statistical methods that uses modern computational power to simulate distributional properties of estimators and test statistics. This book describes computationally-intensive statistical methods in a unified presentation, emphasizing techniques, such as the PDF decomposition, that arise in a wide range of methods.The book assumes an intermediate background in mathematics, computing, and applied and theoretical statistics. The first part of the book, consisting of a single long chapter, reviews this background material while introducing computationally-intensive exploratory data analysis and computational inference.The six chapters in the second part of the book are on statistical computing. This part describes arithmetic in digital computers and how the nature of digital computations affects algorithms used in statistical methods. Building on the first chapters on numerical computations and algorithm design, the following chapters cover the main areas of statistical numerical analysis, that is, approximation of functions, numerical quadrature, numerical linear algebra, solution of nonlinear equations, optimization, and random number generation.The third and fourth parts of the book cover methods of computational statistics, including Monte Carlo methods, randomization and cross validation, the bootstrap, probability density estimation, and statistical learning.The book includes a large number of exercises with some solutions provided in an appendix.

Buch. Zustand: Neu. Neuware -Stimulation of the immune system¿s ability to control and destroy tumors cont- ues to be the goal of cancer immune therapy; but the scope has rapidly expanded; approaches are constantly updated; new molecules are continually introduced; and immune mechanisms are becoming better understood. This book has no intention of covering every aspect of immune therapy but rather focuses on the novelty of cancer immune therapy in an attempt to give readers an opportunity to absorb the new aspects of immune therapy from a single source. In this regard, three areas were selected: cytokine immune therapy, cell-based immune therapy, and targeted immune therapy. In each of these three sections, only the novel aspects of immune therapy were described instead of attempting to cover any historical achievement. In the first section, Cytokine Immune Therapy, the IL12 family, IL18, IL21, IL24, IL28, and IL29 were emphasized in regard to the an- tumor function and application in treating tumors. Most of these selected cyt- ines were discovered in last 10 years. In the second section, Cell-based Immune Therapy, the focus was engineering potent immune regulatory or effector cells such as dendritic cells, T cells, and stem cells. Cell engineering design is primarily based on the increased understanding of the interaction of tumor antigen-presenting cells, antigen- specific effector cells, and the tumor microenvironment.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 356 pp. Englisch.

Buch. Zustand: Neu. Neuware -In recent years, new mathematical methods and tools have been developed and - plied extensively in the eld of aerospace engineering, for example, nite element method,computational uiddynamics, optimization,control,eigenvalues problems. The interaction between aerospace engineering and mathematics has been sign- cant in the past for both engineers and mathematicians and will be even stronger in the future. The School of Mathematics ¿Guido Stampacchiä of the ¿Ettore Majoranä FoundationandCentreofScienti cCultureisthemostappropriatesiteforaerospace engineers and mathematicians to meet. The present volume collects the papers p- sented at the Erice Workshop held on September 8¿16, 2007, which was organized in order to allow aerospace engineers and mathematicians from Universities, - search Centres, and Industry to debate advanced problems in aerospace engineering requiring extensive mathematical applications. Theeditorsarecon denttocapturetheinterestofpeoplefrombothacademiaand industry, particularly, young researchers working on new frontiers of mathematical applications to engineering. The workshop was dedicated to Angelo Miele, Professor at Rice University in Houston, on the occasion of his 85th birthday. Angelo Miele is both an eminent mathematician and a famous engineer, among other activities, able to conceive new scenarios for space exploration. He has been the advisor of many PhD students at Houston, who became well-known professors in universities worldwide and are speakers at this workshop.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 548 pp. Englisch.

Buch. Zustand: Neu. Neuware - For more than five decades Bertram Kostant has been one of the major architects of modern Lie theory. Virtually all his papers are pioneering with deep consequences, many giving rise to whole new fields of activities. His interests span a tremendous range of Lie theory, from differential geometry to representation theory, abstract algebra, and mathematical physics. Some specific topics cover algebraic groups and invariant theory, the geometry of homogeneous spaces, representation theory, geometric quantization and symplectic geometry, Lie algebra cohomology, Hamiltonian mechanics, modular forms, Whittaker theory, Toda lattice, and much more. It is striking to note that Lie theory (and symmetry in general) now occupies an ever increasing larger role in mathematics than it did in the fifties.This is the first volume (1955-1966) of a five-volume set of Bertram Kostant's collected papers. A distinguished feature of this first volume is Kostant's commentaries and summaries of his papers in his own words.

Buch. Zustand: Neu. Neuware - One of the greatest challenges facing modern global health is how to include the most marginalized and impoverished people in international efforts to promote social and economic development. In Disability and International Development disability rights are situated within the broader context of global health and the need for much greater inter-sector collaboration. Reports from a broad cross-section of low- and middle-income countries-locales as diverse as Zimbabwe, Bolivia, Kyrgyzstan, and Papua New Guinea-move beyond surface discussions of 'what is working' and 'what shows promise' to discuss political and governance contexts, the roles of disabled persons in research by outsiders, concurrent struggles (e.g., women's or children's rights), and instructive inroads made by community activists and national Disabled People's Organizations. The results are provocative, and offer new lenses for viewing both the issues and the populations they affect.Each of the book'schapters spotlights a topic as representative of the enormity and immediacy of challenges to inclusive global health, including:The impact of international human rights law on domestic law and local traditions.The effect of failed states on the lives of people with disabilities. Empowerment and advocacy: disability organizations and movements.HIV/AIDS interventions with disabled persons.Assistive technologies in low-income countries.Strategies for improving the lives of children with disabilities.Cross-disciplinary as well as cross-cultural, Disability and International Development will attract a wide audience of professionals in rehabilitation, social welfare and human rights; governmental and non-governmental organizations and disabled people's organizations; researchers and practitioners. It will also be relevant to those working in health and welfare administration, health policy, international aid and development, and human rights. In addition, graduate students in disability studies, public and global health and international development should find this an important guide to the future of these fields.

Buch. Zustand: Neu. Neuware - Mathematical Biology has grown at an astonishing rate and has established itself as a distinct discipline. Mathematical modeling is now being applied in every major discipline in the biological sciences. Though the field has become increasingly large and specialized, this book remains important as a text that introduces some of the exciting problems which arise in the biological sciences and gives some indication of the wide spectrum of questions that modeling can address.

Buch. Zustand: Neu. Neuware -Algebraic Cryptanalysis bridges the gap between a course in cryptography, and being able to read the cryptanalytic literature. This book is divided into three parts: Part One covers the process of turning a cipher into a system of equations; Part Two covers finite field linear algebra; Part Three covers the solution of Polynomial Systems of Equations, with a survey of the methods used in practice, including SAT-solvers and the methods of Nicolas Courtois.Topics include:Analytic Combinatorics, and its application to cryptanalysisThe equicomplexity of linear algebra operationsGraph coloringFactoring integers via the quadratic sieve, with its applications to the cryptanalysis of RSAAlgebraic Cryptanalysis is designed for advanced-level students in computer science and mathematics as a secondary text or reference book for self-guided study. This book is suitable for researchers in Applied Abstract Algebra or Algebraic Geometry who wish to find more applied topics or practitioners working for security and communications companies.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

Buch. Zustand: Neu. Neuware -Electron backscatter diffraction is a very powerful and relatively new materials characterization technique aimed at the determination of crystallographic texture, grain boundary character distributions, lattice strain, phase identification, and much more. The purpose of this book is to provide the fundamental basis for electron backscatter diffraction in materials science, the current state of both hardware and software, and illustrative examples of the applications of electron backscatter diffraction to a wide-range of materials including undeformed and deformed metals and alloys, ceramics, and superconductors.The text has been substantially revised from the first edition, and the authors have kept the format as close as possible to the first edition text. The new developments covered in this book include a more comphrensive coverage of the fundamentals not covered in the first edition or other books in the field, the advances in hardware and software since the first edition was published, and current examples of application of electron backscatter diffraction to solve challenging problems in materials science and condensed-matter physics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 428 pp. Englisch.