Geraghty (Mehr als 3.800 Ergebnisse)

Paperback. Zustand: Fair. Original. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

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Paperback. Zustand: Good. Gripping, emotional and uplifting a novel about the true power of friendship. a tender, emotional and uplifting read I loved it Lucy Diamond A superb writer the Irish Jojo Moyes Irish Examiner.

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Zustand: Acceptable. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

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Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Hardback. Zustand: Very Good. Advances in medicine have made possible better treatments for widespread, familiar human illnesses like cancer, diabetes, and heart disease. Yet there are thousands of much less common diseases, most of genetic origin, each classed as rare because it afflicts only a small number of people. These patient groups were long ignored by a pharmaceutical industry that judged them too small to provide a return on the investment needed to develop an effective remedy. Yet these orphaned diseases collectively caused misery and expense, often far greater than did more common ailments, for tens of millions of individuals and their families. Forty years ago, a revolution that transformed the prospects of patients with rare diseases was lit by three sparks. The passage of the 1983 U.S. Orphan Drug Act resulted from public pressure brought by rare disease patients, their families, and advocates. The AIDS epidemic triggered additional activism, compounded when patients with the rare disease hemophilia became HIV-positive after infusion of tainted blood products. And the third spark was the emergence in the early 1980s of biotechnology companies like Genentech, Amgen, and Biogen employing then-new genetic engineering instead of conventional approaches to pharmaceutical development. Soon after, Genzyme became the first company to develop a treatment for a rare genetic disorder, Gaucher disease, which would come to transform the industry. Jim Geraghty has been a passionate participant in the orphan drug revolution since its inception--a leader in the field as a strategy consultant, biotechnology executive, and venture entrepreneur. His book is in part a history, with eyewitness accounts of advances as they occurred and portraits of the pioneering scientists and physicians, tireless activists, and visionary business leaders who made the revolution happen. And it tells deeply personal stories of patients and parents willing to risk new, untried therapies. But Geraghty also uses his exceptional experience and vantage point to look forward to the immense promise of the newest technologies like gene therapy and gene editing for the treatment of patients today and tomorrow. He concludes with thoughtful consideration of important questions. Why do drugs to treat orphan diseases cost so much? How can we ensure they are affordable? How can their effectiveness be responsibly assessed? And how can access to them be expanded internationally? This book graphically and poignantly illustrates how far an important healthcare revolution has come and reminds us that if not nurtured, it could end before its immense promise has been fulfilled.…

Paperback. Zustand: Good. One afternoon a hungry mosquito flies over a steamy swamp. Just behind her hovers a greedy dragonfly, and behind the dragonfly waits a famished frog. . . . And so the story goes, with each hungry creature too intent on its dinner to be aware of the danger stalking it from behind.…

Paperback. Zustand: Fair. One afternoon a hungry mosquito flies over a steamy swamp. Just behind her hovers a greedy dragonfly, and behind the dragonfly waits a famished frog. . . . And so the story goes, with each hungry creature too intent on its dinner to be aware of the danger stalking it from behind.…

Paperback. Zustand: Fair. First Edition. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

paperback. Zustand: Good.

paperback. Zustand: Fair.

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Zustand: very_good. Fast Free Shipping â" Very Good condition book with a firm cover and clean pages. Shows normal use and some light wear or limited notes markings. A solid, nice copy to enjoy.

Zustand: very_good. Fast Free Shipping â" Very Good condition book with a firm cover and clean pages. Shows normal use and some light wear or limited notes markings. A solid, nice copy to enjoy.

Zustand: Good. Item in very good condition! Textbooks may not include supplemental items i.e. CDs, access codes etc.

Mass Market Paperback. Zustand: Fair. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Paperback. Zustand: Very Good. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting.

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Hardcover. Zustand: Fair. First US. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Paperback. Zustand: Good. The authors of this collection are seven older women from diverse backgrounds who are members of a long-standing Hudson Valley writing group composed of academics, a social worker, a psychiatric nurse, a teacher, and a lawyer. Some are retired, some are still working, some are musicians. All are volunteers, activists, and artists. The sections of the book--Remembrance, Joy, Visibility, Resistance, Resilience, Transformation, Aging, and Bearing Witness--grew from the authors' individual passions and from their collective perspective of being women-of-a-certain-age in a culture that tends to render older women invisible, irrelevant. This collection is filled with honest, insistent poetry and prose that demands to be heard by readers of all ages, genders, and perspectives.…

Paperback. Zustand: Good. From the origins of the SAS behind Rommel's lines in the Sahara through the Malayan emergency, the Arabian skirmishes in Oman and Yemen, the debacle in Gibraltar and the regiment's unique role in the Gulf War, Tony Geraghty examines their successes and failures, the different ways successive British governments have exploited their expertise, their training methods and the skills the men acquire. He has spoken to the soldiers and officers who took part in the SAS' many operations, gaining insight into their activities, philosophy and morale. The author includes material on the Falklands campaign, the shoot to kill debate and previously unknown facts of the SAS' activity during the Gulf War. He has spoken to those who operated far behind the Iraqi lines and obtained previously unpublished photographs of their presence there. As with the original edition, this is a portrayal of a regiment always on call for the riskier military activities and who occupy a special place in the British Army. Tony Geraghty was the Sunday Times Defence Correspondent during the 1970s.…

Paperback. Zustand: Fair. Gripping, emotional and uplifting a novel about the true power of friendship. a tender, emotional and uplifting read I loved it Lucy Diamond A superb writer the Irish Jojo Moyes Irish Examiner.